prevalence

PSA TestingHow Much is Too Much?

...nd returned within five days. Given the widespread prevalence of prostate cancer the search for markers more accurate than PSA are now being widely sought. Prior to their availability, PSA testing, while in a far more limited role, will continue to perform useful work....

Controlling the Spread of Healthcare Associated Methicillin Resistant Staphylococcus aureus Requires Active Surveillance

...ureus isolates are methicillin resistant, with the prevalence of MRSA strains being almost as high in non-ICU as in ICU settings. MRSA is also common in long-term care facilities. MRSA may colonize mucosal or epithelial surfaces, the most common colonized site being the anterior nares. Sites of colonization a...

Non-Invasive Diagnostic Tests for Celiac Disease

...ge of 11 years before diagnosis. Although the true prevalence of CD is difficult to estimate because of its vari...ers among European and American Caucasians, with a prevalence in the general population that is likely close to 1%. The new serologic tests have altered the class...

Clinical Data Suggest Decreased Bleeding Risk in People With Severe Hemophilia A While Maintaining Factor VIII Levels Above One Percent

...le in the world have hemophilia, corresponding toa prevalence of 15 to 20 in every 100,000 males born worldwide. About ADAPT The ADAPT (Analysis of Data from ADVATE Prospective Trials)research program was initiated to further investigate and explorethe expanding ADVATE clinical study program database for addi...

International ENDORSE Study Shows That the Majority of Hospitalized Patients Surveyed are at Risk for VTE and Many do not Receive Recommended VTE prophylaxis

...tting. Lack of awareness and uncertainty about the prevalence ofpatients at risk for VTE are among the major rea... The main objectives of ENDORSE were to assess the prevalence ofVTE risk in the acute hospital care setting and to determine theproportion of at-risk patients who...

Cytos Biotechnology Reports Results from Phase IIa Study with CYT003-QbG10 in Patients Suffering from Atopic Dermatitis

... for the initiation andmaintenance of allergy. The prevalence of allergic diseases hasdramatically increased over the last decades, especially inindustrialized countries. It is estimated that today more than 20%of the world population suffers from allergic diseases1. AD is a certain type of eczema. It is a com...

Major New Review Supports the Broader Potential of CeNeS COMT Inhibitor Discovery Programme

...ubstantially over the nextdecade with an increased prevalence of the disease as a consequenceof the ageing population. COMT inhibitors currently have more thana 10% share of the Parkinson's disease market by value and theirusage is growing. About Schizophrenia Schizophrenia is a debilitating mentalillness char...

Speedel Reports Successful SPP635 Phase IIa Trial in Hypertension

...the blood to flow into the heart. Due to its wide prevalence and impact on cardiovascular health,hypertension is a major cause of disease and death in Europe andNorth America. More than one in three Europeans and North Americansover the age of 35 suffers from hypertension - but for the vastmajority of patients...

Tranzyme Pharma Presents Initial Phase IIa Data for its Novel Ghrelin Agonist, TZP-101, in Patients with Diabetic Gastroparesis

...etiology (36%), and post-surgical causes (13%).The prevalence rate of gastroparesis is especially high amongdiabetic patients, as up to 50% of diabetics worldwide are reportedto suffer from gastroparesis. Gastroparesis has seriousimplications in diabetic patients, where failure to tolerate foodand oral medicati...

Largest National U.S. Healthcare Facility MRSA Study Reveals Infection Rates Eight Times Greater Than Previous Estimates

... of1,237 U.S. healthcare facilities, examining the prevalence ofMethicillin-resistant Staphylococcus aureus (MRS...study. The surveytook a one-day "snapshot" of MRSA prevalence at these facilitiesbetween October and November 2006. The detailed survey looked atfacilities caring...

Arisaph Pharmaceuticals Announces Results of its Potent Smart DPP-4 Inhibitor, ARI-2243, at the ADA

...or healthcare problem throughout the worldwith the prevalence of the disease projected to double to 300million cases worldwide by the year 2025 according to the WorldHealth Organization. Certain statements in this press release, including statementsregarding the Company's research and development effort, theCo...

Nationwide MRSA Prevalence Study to Demonstrate Full Scope of 'Superbug' Threat Facing U.S. Healthcare Facilities and Patients

...IC: WHAT: -- First nationwide study of the prevalence of Methicillin-resistant Staphylococcus aure...m, in U.S. healthcare facilities. -- MRSA prevalence study findings significantly exceed previous estimates and will for the first time provide a p...

New Study Shows That telmisartan has Greater Renoprotective Potential Thanlosartan in Hypertensive Patients With Type 2 Diabetes

...ients as well as healthcare systems worldwide. The prevalence of diabetes isprojected to increase at an alarmin...56(3):213-215. (3) Wild S et al.Global prevalence of diabetes: estimates for the year 2000 andprojections for 2030. Diabetes Care 2004; 27:1047- ...

Remicade Two Year Data in Ankylosing Spondylitis Show Improvement in Spinal Mobility and Spinal Inflammation

...paign, estimates that on theEuropean continent, AS prevalence ranges from 0.2 to 1 percent ofthe entire population. The Spondylitis Association of Americaestimates that between 350,000 and one million people in the U.S.suffer from Ankylosing Spondylitis. About REMICADE REMICADE is a monoclonal antibody that s...

Neurocrine Biosciences Announces New Research Studies Presented at APSS Reveal Significant Under-Diagnosis of Insomnia

... -- The purpose of this study was to examine the prevalence and clinical characteristics of subtypes of insomnia in the general population. -- According to a survey of 14,997 U.S. adults, 43.3% of respondents self-reported sleeping difficulties related to insomnia; compared to only 8....

Valopicitabine Combined with Standard of Care Cleared Hepatitis C Virus in 72% of Patients Who Completed 12 Weeks of Treatment in a Phase II Trial

...er transplantation in the United States.(2) As the prevalence ofsevere liver disease attributable to hepatitis C rises, deaths dueto complications from hepatitis C infection, currently 8,000 to10,000 per year in the United States, are increasing and areexpected to triple by 2010.(3) Conference Call Information...

Pilot Phase 3 Results of NovaCardia's KW-3902 for Acute Congestive Heart Failure Presented at Late-Breaking Session of Heart Failure Congress 2007

...ng the early stages of cardiovasculardiseases, the prevalence of CHF is increasing. Approximately550,000 new cases of CHF are reported in the United States eachyear, according to the AHA. About NovaCardia NovaCardia is a clinical-stage pharmaceutical company focused ondeveloping drugs to treat major cardiovas...

Trial Results with Intranasal Fentanyl Hold Promise for Treatment of Breakthrough Pain in Cancer

...uthor%5D">Camell H . Breakthrough cancer pain: prevalence andcharacteristics in patients in Catalonia, Spain. <a target="_blank"href="javascript:AL_get(this,%20'jour',%20'J%20Pain%20Symptom%20Manage.');"> Journal of Pain and Symptom Management 2002;24:45–52 <p class="Bulletedlistnumbers...

Cogane Data Presented at ‘11th International Congress of Parkinson’s Disease and Disorders’

...ts the gradual loss of dopaminergicneurones. The prevalence of the disease is estimated to be 100 to 200 per100,000 population (Source: Datamonitor). In the US alone, thereare estimated to be one million patients with diagnosed Parkinson'sdisease with associated healthcare costs to the economy of $25billion (...

Clinical Data Reported on Vidaza in Hematologic Malignancies and Advanced Solid Tumors

...h Vidaza should not nurse. About MDS The highest prevalence of MDS is in patients over 60 years ofage. According to the American Cancer Society and the AplasticAnemia and MDS International Foundation, there are approximately10,000-30,000 new cases of MDS in the United States each year.Survival ranges from six...

Soliris Effective in PNH Patients With History of Aplastic Anemia and Myelodysplastic Syndromes

...lp hematologists-oncologists better understand the prevalence andclinical characteristics of PNH in patients with bone marrowdisorders. Many of these patients may benefit from treatment withSoliris. Data from EXPLORE may also help us define and implementscreening protocols for PNH." PNH is a rare, disabling an...

In New Study, Duloxetine Was Equally Effective, Regardless of Switch Method, in Reducing Painful Symptoms in Ssri Non- or Partial-responders with Depression

...gat study entry. This new analysis focused on the prevalence and severity of painfulsymptoms following the switch to duloxetine and in relation toswitch method. The study participants, as a group, had average painscores indicating clinically significant physical pain. Ten weeksafter switching to duloxetine, pa...

AEterna Zentaris' Partner, Spectrum, Discloses Detailed Phase 2 Data for Ozarelix, in BPH at Annual AUA Meeting

... According to Decision Resource, in2004, the total prevalence cases of BPH in the major pharmaceuticalmarkets was estimated at 56 million men and is expected to increaseto 65 million cases by 2014. The BPH market is a significantmarket, with current annual sales of more than $2.6 billion. About AEterna Zentari...

Forest Laboratories, Inc. and Cypress Bioscience, Inc. Announce Positive Results of Phase III Study for Milnacipran as a Treatment for Fibromyalgia Syndrome

...nited States afterosteoarthritis. Despite the high prevalence and severity of thissyndrome, there are no treatments specifically approved for FMS inthe United States or elsewhere and the addressable patientpopulation is not yet well established. For more information aboutfibromyalgia, visit <a target="_blan...

Positive Clinical Data on CC-10004 Confirms Potential as Novel Oral Approach to Treating Inflammatory Diseases

...patients and theirfamilies. Despite the burden and prevalence of inflammatorydiseases, there have been relatively few innovative breakthroughsin identifying their cause, treatment or cure. About CC-10004 CC-10004 is a member of a proprietary pipeline of novel smallmolecules with anti-inflammatory activities t...

New Studies Evaluating NexiumIn Pediatric GERD To Be Presented At Annual Digestive Disease Week Meeting

...atric uses have not been established. The exact prevalence of GERD in children is unknown. However,GERD can l...e such study, a practice-based surveylooked at the prevalence of GERD symptoms in 3-17 year oldchildren. The study included 566 parents of otherwise healthy 3-9ye...

Hypertension Education Foundation Survey Results Announced At American Society For Hypertension Annual Meeting Suggests Improved Control Of High Blood Pressure, But Misconceptions Still Exist

...." Misperceptions Persist The survey reveals the prevalence of some ongoingmisunderstandings about hypertension, and highlights that somemisperceptions were more prevalent in certain ethnic groups thanothers. For example, nearly a quarter (22%) of African-Americansurvey respondents held the belief that HBP me...

New Data Highlights Potential of SPP100 (Tekturna) as Gold Standard Therapy in Treatment of Hypertension

...patients. This may be clinically usefulbecause the prevalence of isolated systolic hypertension isincreased in elderly patients, and elevated systolic blood pressureis difficult to control. * Aliskiren 150 and 300 mg monotherapy wasequally well tolerated in elderly and younger patients, and in menand women with...

Data Published in The Lancet Show Gardasil was 100 Percent Effective in Preventing High-Grade Vulvar and Vaginal Lesions Caused by HPV Types 16 and 18

...neral population of American women with respect to prevalence of HPVinfection and disease at enrollment. Analyse...DASIL, described above, willdepend on the baseline prevalence of HPV infection related to vaccinetypes in the population vaccinated and the incidence of HPV infec...

Ulcerative Colitis (UC) Sufferers Find UC Quite Disruptive to Many Aspects of Daily Life

...rd ofit but know little about it, even though UC's prevalence approachesthe numbers for HIV/AIDS and Parkinson's in the United States. More than two-thirds of UC patients report that having UC isembarrassing to them (70 percent) and that they are reluctant totell people about their condition (66 percent). With...

Isis Pharmaceuticals Updates Its Positive Phase 2 Data for ISIS 301012 in Familial Hypercholesterolemia Patients

...ple, but heterozygous FH ismuch more common with a prevalence of approximately one in every500 people. ABOUT ISIS PHARMACEUTICALS, INC. Isis is exploiting its expertise in RNA to discover and developnovel drugs for its product pipeline and for its partners. TheCompany has successfully commercialized the world...

New England Journal of Medicine Publishes New Data on Gardasil, Merck's Cervical Cancer Vaccine

...neral population of American women with respect to prevalence of HPVinfection and disease at enrollment. Analyse...DASIL, described above, willdepend on the baseline prevalence of HPV infection related to vaccinetypes in the population vaccinated and the incidence of HPV infec...

Avanir Pharmaceuticals Presents IEED Prevalence and Updated Zenvia Long-Term Safety Data at AAN Annual Meeting

...g Zenvia(TM)(dextromethorphan / quinidine) and the prevalence of InvoluntaryEmotional Expression Disorder (IEED)...or their caregivers, weresurveyed to determine the prevalence of IEED symptoms. The resultsindicate that at least 1.8 million neurologic patients in the U.S.suffe...

Amsterdam Molecular Therapeutics BV to present preclinical proof-of-concept data on its gene therapy AMT-020 to treat acute intermittent porphyria

...individuals,however, in some regions of Sweden the prevalence of the diseasecan be as high as 60-100 cases per 100,000 population. Women aremore commonly affected than men. About the Centro de Investigación Médica Aplicadaat the University of Navarra CIMA is a biomedical research project which a...

Mircera Effective in Stabilising Haemoglobin Levels in Elderly Patients With Kidney Disease on Dialysis

...thly maintained stable haemoglobin levels." The prevalence of CKD patients on dialysis is projected to grow7 per cent per year and it is estimated that by 2010, there will beover 2 million people worldwide on dialysis.(i) These results, based on a pooled analysis from two large MIRCERAPhase III maintenance ...

Addex Reports Positive Results in Phase IIa Clinical Trial With ADX10059 in Migraine

...h an attackduration of between 4 and 72 hours. The prevalence of migraine isestimated at 12%, affecting approximately 30 million people in theUnited States. The disabling nature of migraine often results in asignificant deterioration in quality of life for the sufferers andhas a significant impact upon their wo...

Antares Pharma Announces Positive Results from Application Site Study for Anturol

...ny age, it is most commonamong the elderly, with a prevalence of 33% to 61% in people overage 65. Despite its rising prevalence with age, OAB is treatable atevery age. In recent published reports the market is described asone of...

Idenix Reports Results from Two Phase IIb Studies of the Combination of Valopicitabine and Pegylated Interferon in Hepatitis C Genotype-1 Patients at the 42nd Annual Meeting of the European Association for the Study of the Liver

...er transplantation in the United States.(4) As the prevalence ofsevere liver disease attributable to hepatitis C rises, deaths dueto complications from hepatitis C infection, currently 8,000 to10,000 per year in the United States, are increasing and areexpected to triple by 2010.(5) About Idenix Idenix Pharma...

First Pharmacoeconomic Analysis with Long-Term Data Showed Copaxone Was More Cost-Effective Than Interferon Beta Therapies for Treatment of Relapsing-Remitting Multiple Sclerosis (RRMS)

...sease of thecentral nervous system with an overall prevalence rate ofapproximately 400,000 people. The annual cost of MS (in 1994 $US)is estimated to be between $6.8 and $13.6 billion, composed largelyof indirect costs for formal/informal care and lost earnings.Previous research finds that costs associated with...

First-of-its-Kind National Report Reveals Estimated High Prevalence and Heavy Cost of Type 2 Diabetes Complications in America

...swire/ -- A first-of-its-kindreport looking at the prevalence and cost of type 2 diabetescomplications shows tha...ted complications in the United States. Dataon the prevalence of diabetes-related complications were derivedfrom the National Health and Nutrition Examination Sur...

Large Study Shows that Presence of Neutralizing Antibodies Did Not Predict Clinical Response to Betaseron Treatment

...271)using the myxovirus protein A assay (MxA). The prevalence ofpersistently high neutralizing antibodies in the Australian cohort,which included patients regardless of clinical response toBetaseron, was 37%. This finding was similar to the reportedincidence seen in Betaseron clinical trials. The incidence ofpe...

Trichomoniasis: Most Common Curable STD in U.S. Affects 7.4 Million Annually

...f the men did not show symptoms (1). "Despite its prevalence and the consequences of leaving ituntreated, routine testing is not being conducted fortrichomoniasis," stated Dr. Jane Schwebke, professor of infectiousdiseases at the University of Alabama at Birmingham. "Becausepatients may not experience symptoms...

Safety Analyses of Clinical Data for Bifeprunox in Patients with Schizophrenia Showed a Favorable Weight and Lipid Profile, Similar to Placebo

...particularly because of our concerns aboutthe high prevalence of metabolic syndrome in this patientpopulation," says Herbert Y. Meltzer, M.D., Professor of Psychiatryand Director of the Division of Psychopharmacology, VanderbiltUniversity Medical Center. "If approved, bifeprunox may be animportant alternative f...

Increasing Proportion of Cardiovascular Disease Due to Diabetes Over the Last 50 Years

... time periods and there was also an increasein the prevalence of obesity. “Increasing Cardiovascular Burden Due to Diabetes: theFramingham Heart Study” is published in the March 27th issueof Circulation and is also currently available online (March 12Rapid Access issue). Caroline Fox, M.D., lead...

The American Liver Foundation Urges Cautious Optimism about CDC Report on Declining Acute Hepatitis Infection Rates

...hat affect over fivemillion Americans and that the prevalence of chronic hepatitis Cinfection is actually increasing. This is in response to thearticle "Surveillance for Acute Viral Hepatitis -- United States,2005," published by the CDC in their publication Morbidity andMortality Weekly Report. Acute, or short...

Alzheimer's Growth Shows Need for Increased FDA Funding

...he onset or progression ofAlzheimer's disease, the prevalence could soar to 7.7 millionpeople with the disease by 2030 and 16 million by the middle of thecentury. More information on the Alzheimer's Association report canbe found at <a target="_blank" href="http://www.alz.org/news_and_events_rates_rise.asp"...