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Pressure in Medical Technology

R788 in TASKi3 Clinical Trial Does Not Meet Efficacy Endpoints in RA Patients Who Had Previously Failed Biologic Therapies - Results Incongruent

... dose group. The mean increase in blood pressure from baseline at 3 months, using a last ... patients in the 100 mg bid dose group had blood pressure medication adjusted or in some cases initiated ... For those patients who had their dose of blood pressure medications adjusted or initiated, their ...

FDA Approves Tekturna HCT(R) as Initial Treatment in Patients Unlikely to Achieve Their Blood Pressure Goals With a Single Agent

... to need multiple drugs to achieve their blood pressure goals. Tekturna HCT is a single-pill combination ... (HCTZ), one of the most commonly-used high blood pressure medications. The FDA approval of ... of Tekturna and HCTZ offered greater blood pressure reductions than either drug alone. "Up ...

Rigel's R788 Significantly Improves Rheumatoid Arthritis in Phase 2b Clinical Trial

... dose groups. The mean increase in blood pressure from baseline at 6 months, using a last ... 100 mg bid dose groups, respectively, had blood pressure medication adjusted or in some cases initiated ... with 7% of the placebo patients. The blood pressure was successfully reduced in these patients, and ...

Exenatide Once Weekly Provided Sustained Improvements in Glycemic Control With Weight Loss Over Two Years: DURATION-1 Interim Long-Term Data Presented at ADA 2009

... Improvements in Systolic Blood pressure and Triglycerides Also Observed NEW ORLEANS, ... loss, as well as improvements in systolic blood pressure and triglycerides, through two years of treatment ... was a significant reduction in systolic blood pressure (SBP). "These two-year DURATION-1 data ...

Ongoing Landmark ROADMAP Study Demonstrates Significant Improvement in Blood Pressure Control at One Year, According to Blinded Results

... May 8 /PRNewswire/ -- Blinded one-year blood pressure (BP) reduction data from the ongoing landmark ... the secondary objective was to measure cuff blood pressure (BP). The double-blinded one-year data ... physicians. "It is essential to manage blood pressure very aggressively in diabetics because their ...

New Data Shows Blood Pressure Reduction Therapy with BENICAR(R) and BENICAR HCT(R) Effectively Reduces Blood Pressure in Elderly Patients to Target Blood Pressure

... reduction in 24-hour ambulatory systolic blood pressure (SBP) of 25.7 mm Hg among patients with an ... also saw their 24-hour ambulatory diastolic blood pressure (DBP) drop a mean of 12.3 mm Hg. The BeniSILVER ... was designed to investigate the safety and blood pressure (BP)-lowering efficacy of BENICAR and BENICAR HCT ...

New Data Shows AZOR(R) (amlodipine and olmesartan medoxomil) Significantly Improves 24-Hour Ambulatory Blood Pressure

... from the AZ OR(R) T rial E valuating Blood pressure Reductions and C ontrol ( AZTEC ) demonstrated ... 24-hour ambulatory reductions in systolic blood pressure (SBP) of 21.4 mm Hg and diastolic blood pressure (DBP) of 12.7 mm Hg. In addition, 71 percent of ...

February 2009 Mayo Clinic Women's HealthSource Highlights Diabetes and Heart Disease, Going Vegetarian and Tinnitus

... twice a year. Blood pressure: High blood pressure is a common partner to diabetes. For people with ... has shown that most adults with high blood pressure and diabetes require multiple drug therapies to reach blood pressure goals. The bottom line: Risks and ...

NicOx' Naproxcinod Shows Robust Blood Pressure Results in Phase 3 Pooled Analysis

... Both naproxcinod doses showed a similar blood pressure profile to placebo, in contrast to naproxen which ... lead to the onset of new episodes of high blood pressure or worsening of pre-existing hypertension. Both ... of previous studies and show a similar blood pressure profile to placebo in a large population ...

Third Pivotal Phase 3 Study for NicOx' Naproxcinod Shows Positive Efficacy, Safety and Blood Pressure Results

... (GI) adverse event rate and a similar blood pressure profile to placebo. Naproxcinod is the most ... hip OA, in addition to providing reassuring blood pressure and safety data," said Thomas J. Schnitzer, MD, ... blood pressure profile The blood pressure data for naproxcinod 750 mg bid were consistent ...

NicOx Announces Favorable Blood Pressure Data for Naproxcinod in a Large ABPM Study

... results from a 118 patient Ambulatory Blood pressure Monitoring (ABPM) trial (the 111 study), which compared the 24-hour blood pressure profile of escalating doses of naproxcinod and ... was the mean 24-hour ambulatory systolic blood pressure (SBP) measured by ABPM over the whole study ...

Durezol(TM) in the Treatment of Uveitis and Ganciclovir in the Treatment of Herpetic Keratitis: Studies of Treatments for Leading Causes of Blindness to Be Presented

... experienced criterion increases in intraocular pressure (defined as a pressure of greater than or equal to 21 mmHg and a change ... cornea. It is important to monitor intraocular pressure when using ophthalmic steroids. The use of ...

Grapes May Aid a Bunch of Heart Risk Factors, U-M Animal Study Finds

... Research shows that grape intake lowered blood pressure and signs of heart muscle damage, and improved ... -- Could eating grapes help fight high blood pressure related to a salty diet? And could grapes calm ... from a research breed that develops high blood pressure when fed a salty diet. In all, after 18 weeks, ...

Sirion Therapeutics Announces Positive Pivotal Uveitis Data for Durezol(TM)

... experienced criterion increases in intraocular pressure (defined as a pressure of greater than or equal to 21 mmHg and a change ... cornea. It is important to monitor intraocular pressure when using ophthalmic steroids. The use of ...

Video: Sirion Therapeutics Launches Durezol for Postoperative Ocular Inflammation and Pain

... increase in intraocular pressure, defined as a pressure of greater than or equal to 21 mmHg and a change ... reduced inflammation and pain. Mean intraocular pressure for all study groups remained within the normal ... cornea. It is important to monitor intraocular pressure when using ophthalmic steroids. The use of ...

NicOx Announces Second Naproxcinod Pivotal Phase 3 Study (302) Meets Efficacy Primary Endpoints and Supports Non-Detrimental Blood Pressure Effect

... naproxcinod's non-detrimental effect on blood pressure and are consistent with those observed in the 301 ... A post hoc pooled analysis of the blood pressure data from the 301 and 302 studies showed a ... A pre-specified analysis of the pooled blood pressure data from the three phase 3 studies will be ...

Novo Nordisk New Data From a Phase 3 Study Confirms Clinical Benefits of Once-Daily Liraglutide in the Management of Type 2 Diabetes

... glucose lowering (HbA1c), weight loss, blood pressure reduction and improvements in beta-cell ... to a statistically significant decrease in blood pressure as seen in three of the other LEAD(TM) studies: ... while also consistently lowering weight and blood pressure and enhancing beta-cell function." About the ...

New Implant Device Remotely Monitors Heart Failure Patients at Northwestern Memorial's Bluhm Cardiovascular Institute

... A pressure sensor that is permanently implanted into the ... first researchers using a new wireless pressure sensor technology that allows them to track the pulmonary artery pressure of the subjects while these subjects remain at ...

August 2008 Mayo Clinic Women's HealthSource Highlights Avoiding Blood Pressure Increase at Menopause, Healthful Benefits of Dark Chocolate and Scheduling a Colorectal Exam

... extension 9751. Ways to Avoid Blood pressure Increase at Menopause Five steps to lower blood ... have a blood pressure advantage. Women's blood pressure starts out lower than men's, but the ... Women's HealthSource offers insights on blood pressure changes in women and steps to avoid high ...

NicOx Announces Top-Line Results From Naproxcinod 52-Week 301 Safety Extension

... the results showed that the patients' mean blood pressure was stable for 52 weeks following the completion ... naproxcinod does not increase blood pressure over time. Naproxcinod is NicOx' lead ... naproxcinod. Standardized controlled office blood pressure measurements (OBPM) were performed at each ...

NicOx Completes Enrollment of Two Ambulatory Blood Pressure Measurement (ABPM) Studies for Naproxcinod in Hypertensive OA Patients

... These trials are designed to assess the blood pressure profile of naproxcinod, in comparison to ibuprofen and naproxen, using the Ambulatory Blood pressure Monitoring (ABPM) technique. Results of both ... 2007. They will also complement the Office Blood pressure Measurements (OBPMs) being collected in each of ...

Pressure Cycling Technology (PCT) Results in a Higher Yield of Proteins and in the Extraction of Proteins Not Previously Identified in Cancer, Stroke, and IVF Studies

... These are very exciting results." About pressure BioSciences, Inc. pressure BioSciences, Inc. (PBI) is a publicly traded ... of a novel, enabling technology called pressure Cycling Technology (PCT). PCT uses cycles of ...

Pressure BioSciences, Inc. Announces $850,000 NIH SBIR Phase II Award for the Development of a New PCT-dependent System for Improved Biomarker Discovery, Diagnostics, and Drug Discovery

... and tissues using the Company's patented pressure cycling technology ("PCT"). The Grant is for a ... and related diseases." About pressure BioSciences, Inc. pressure BioSciences, Inc. (PBI) is a publicly traded ...

Blood Pressure Lowering Effect of Hypertension Treatment Device Further Validated in New Studies

... five posters focus on RESPeRATE's effect on blood pressure as measured by 24-hour ambulatory blood pressure monitoring. Three of the posters also present new ... of obtaining vascular risk parameters from blood pressure measurements. The fifth poster demonstrates the ...

New Study Shows BENICAR(R) (olmesartan medoxomil) Reverses Blood Vessel Damage Independent of Blood Pressure Lowering

... Stage 1 hypertension, independent of the blood pressure lowering effects of these agents.(1) In the ... is defined by the JNC 7 as systolic blood pressure (SBP) of 140-159 mm Hg or diastolic blood pressure (DBP) of 90-99 mm Hg.(21) VIOS Study Results ...

NicOx Announces Blood Pressure Analysis From 301 Phase 3 Study for Naproxcinod at EULAR

... announced an additional analysis of the blood pressure data from the 301 phase 3 study, showing ... as naproxen, have the tendency to raise blood pressure to an extent that may increase the rate ... efficacy endpoints (p<0.001). Patients' blood pressure was also measured in the study, with a well ...

New Study Linking 'High Normal' Blood Pressure to Significant Cardiovascular Risk

... as having "high normal" systolic blood pressure through traditional cuff blood pressure measurement may be at serious cardiovascular ... SphygmoCor(R) is a non-invasive central blood pressure assessment technology that has been used by ...

NicOx Completes Patient Enrollment in Third Naproxcinod Pivotal Phase 3 Study

... information on naproxcinod's blood pressure profile in comparison to another ... are known to have the tendency to elevate blood pressure to an extent that may increase the rate of ... patients are undergoing standardized blood pressure measurements at each visit to the clinical center ...

Seven Presentations by Two Independent Research Groups Highlight Advantages of Pressure Cycling Technology (PCT) at Scientific Symposia in Philadelphia, Boston, and New York City

... the advantages of the Company's patented pressure cycling technology (PCT) at three different ... and enhanced analysis of samples. About pressure BioSciences, Inc. pressure BioSciences, Inc. (PBI) is a publicly traded ...

Pharmacopeia's First-in-Class Investigational Therapy PS433540 Achieves Statistically Significant Reductions in Blood Pressure in Hypertensive Patients

... Novel Approach to Blood pressure Management NEW ORLEANS, May 16 ... (DARA), showed statistically significant blood pressure reductions in a Phase 2a study in patients with ... in mean 24-hour diastolic ambulatory blood pressure as well as seated blood pressure. In this ...

Azor(TM) Reduces Blood Pressure in Difficult to Treat Special Populations

... Blood pressure reductions demonstrated in Blacks, ... with high BMI)(3) or require lower blood pressure to achieve control (those with diabetes).(4) ... ABOUT THE ANALYSES RACE/ETHNICITY: Blood pressure control in patients with hypertension ...

New Data Shows 45 Percent of Patients with Stage 1 Hypertension Reached Normotension with BENICAR(R) and BENICAR HCT(R)

... 1 hypertension were able to reach a goal blood pressure (BP) of BENICAR HCT ... Detection, Evaluation and Treatment of High Blood pressure (JNC 7) defines this level as normotension. The ... were able to reach the < 140/90 mm Hg blood pressure goal recommended by the JNC 7 (placebo: ...

Microwave Treatments for Enlarged Prostate Cause Blood Pressure Surges

... prostates experience significant surges in blood pressure that could raise their risk of a heart attack ... found that 42 percent experienced systolic blood pressure surges of more than 30 mm Hg, while 5 percent had ... paper. "Anecdotal reports of adverse blood pressure events during and after transurethral ...

Lotrel, a Single-Pill Combination for Treating High Blood Pressure, Reduced Cardiovascular Events by 20% in High-Risk Patients

... combinations of commonly used high blood pressure medicines in reduction of cardiovascular ... therapies in this study and exceptional blood pressure control rates were ... trial demonstrate that high-risk, high blood pressure patients treated with Lotrel(R) (amlodipine ...

Landmark ONTARGET(TM) Trial Demonstrates Micardis(R) is Equally Effective as Ramipril, with Fewer Discontinuations, in a Broad High-Risk Cardiovascular Population

... patients with normal blood pressure or controlled high blood pressure, and resulted ... risk reduction benefits beyond lowering blood pressure in this high-risk population;(1) these benefits ... cardiovascular patients with normal blood pressure or controlled high ...

Use of PressureWire(R) Yields a More Accurate Assessment of Translesion Pressure Gradients in Peripheral Vasculature, Two New Studies Report

... gradients when compared to catheter-derived pressure gradient (CPG) measurements, according to a paper ... Entitled "Physiologic Evaluation of Translesion pressure Gradients in Peripheral Arteries: Comparison of ... Using this low profile PressureWire for arterial pressure measurement yields a more accurate assessment of ...

Novel PCT Method Unveiled by Pressure BioSciences, Inc. and Collaborators at the Harvard School of Public Health

... animal, plant, and microbial research." About pressure BioSciences, Inc. pressure BioSciences, Inc. (PBI) is a publicly traded ... of a novel, enabling technology called pressure Cycling Technology (PCT). PCT uses cycles of ...

Pharmacopeia Initiates Second Phase 2 Hypertension Study with PS433540 (DARA)

... from baseline in mean seated systolic blood pressure for each dose of PS433540 with placebo. ... include comparisons of changes in blood pressure for each dose of PS433540 with irbesartan. "We ... as reductions in systolic and diastolic blood pressure in non- hypertensive healthy subjects. PS433540 ...

Financial Results for Full Year 2007: NicOx Significantly Advances Clinical Programs

... 301 study) and data from an Ambulatory Blood pressure Monitoring trial at the American Heart ... including a pooled analysis of the Office Blood pressure Measurements, ahead of a projected New Drug ... and has provided successful efficacy and blood pressure results which were presented at the American ...

Pharmacopeia Completes Enrollment in Phase 2 Hypertension Study with PS433540 (DARA)

... that DARA can effectively lower blood pressure in this patient population." Results from Phase ... PS433540 can be expected to lower blood pressure in hypertensive patients. Additional data from ... as reductions in systolic and diastolic blood pressure in non-hypertensive healthy volunteers. ...
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(Date:11/24/2009)... , Rocket science is opening new doors to underst... affect the hearing of a marine mammal or if they...rial sized X-ray scanners that NASA uses to detect...rockets is now allowing scientists to peek inside ... detailed three-dimensional replicas of a whale,s ...
(Date:11/24/2009)... , The atomic-level action of a remarkable class ...y researchers with the Lawrence Berkeley National ... protein crystallography beamline at the Advanced ...tal roles in gene expression and replication, and ... as well as infectious agents, such as the human p...
(Date:11/24/2009)... , BATON ROUGE Antarctica has long held secret... and until recently, there has been very little in...d beneath miles of ice for millions of years. Now,...luding LSU have been funded to the tune of $10 mi...or NSF, to get to the bottom of things literally....
Breaking Biology News(10 mins):Rocket science leads to new whale discovery 2Atomic-level snapshot catches protein motor in action 2Atomic-level snapshot catches protein motor in action 3Atomic-level snapshot catches protein motor in action 4LSU gets to the bottom of things -- in Antarctica 2Judge Rules on SEIU Lawsuit 50208 1Judge Rules on SEIU Lawsuit 50208 2National Expert on Prescription Drug Abuse Addicted Physicians Available for Media Interviews From Hazelden 50206 1National Autism Association Teams Up With 12 Organizations to End Abusive Restraint and Seclusion in Schools 50203 1National Autism Association Teams Up With 12 Organizations to End Abusive Restraint and Seclusion in Schools 50203 2
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(Date:11/26/2009)...wswire/ -- The diabetes population in the United S...d annual medical spending on the disease is projec...y, according to a study published in the December ...Diabetes ® Program (NCDP), a program of Novo ...the University of Chicago. ,, According to the ...
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(Date:11/26/2009)...ons announces a highly effective and unconventiona...to make an economic recovery. , ...he type of challenge that could send ailing holida...vid Benton, business growth expert and author of t...The Rfactor Intensive . “Fear is one of th...
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