powder in Medical Technology

New Powder Speeds Healing of Difficult Foot Wounds

... ) This wound powder is especially promising for the nearly 24 million ... a reduction in amputation rates. "This new powder aggregates, or comes together, in an amazing ... and causes. The wounds were treated with the powder dressing once a week for four to eight weeks. ...

Studies Show AFRESA(R) Controls Post-Meal Sugar Levels With Less Weight Gain and Hypoglycemia Risk for Diabetes Patients

... (insulin human [rDNA origin]) Inhalation powder combined with basal insulin is comparable to ... requesting approval to market AFRESA Inhalation powder and the AFRESA Inhaler for use in adult patients ... product, consisting of AFRESA Inhalation powder pre-metered into single use dose cartridges and ...

AFRESA(R) Phase 3 Pulmonary Function Safety Data in Patients with Diabetes Presented at ADA

... (insulin human [rDNA origin]) Inhalation powder is a well-tolerated, ultra rapid acting insulin ... requesting approval to market AFRESA Inhalation powder and the AFRESA Inhaler for use in adult patients ... product, consisting of AFRESA Inhalation powder pre-metered into single use dose cartridges and ...

Muscadine Grape Skin Dietary Supplement Protects against Cancer Therapy Radiation Side Effects

... the preventative effects of Muscadine grape skin powder on irradiated mice. The mice consumed the powder two days before radiation and showed ... the effects of the Muscadine grape skin powder to pure resveratrol, which also showed evidence ...

Aerovance Initiates Phase IIb Clinical Trial with Aerovant(TM) for the Treatment of Uncontrolled Asthma

... IIb clinical trial, AeroTrial(TM), of inhaled dry powder Aerovant in patients with uncontrolled asthma. ... is a late-stage clinical study using a dry powder formulation and follows positive clinical data ... ( The Lancet 2007, 370: 1422-31). The dry powder formulation that will be used in AeroTrial was ...

Grapes May Aid a Bunch of Heart Risk Factors, U-M Animal Study Finds

... test diet and the control rats receiving no grape powder -- including some that received a mild dose of a ... failure was changed by the addition of grape powder to a high-salt diet," he says. "Although there are many natural compounds in the grape powder itself that may have an effect, the things that ...

Data Show Aerovance's Aerovant(TM) Inhalation Powder is Well Tolerated in Asthma Patients

... from a Phase I trial of its Aerovant inhalation powder that demonstrate good tolerability with no ... the lung, while the PK data confirm that the dry powder inhaler achieved the targeted lung dose. The data ... a single 10 mg dose of Aerovant inhalation powder via the EZ Aer(TM) Inhaler. Serial measurements ...

Phase III Clinical Studies of Aclidinium Bromide Show Statistical Significance vs. Placebo in Patients With Chronic Obstructive Pulmonary Disease (COPD)

... using the Genuair(R)(1) device, a multi-dose dry powder inhaler which operates by a 'one press and ... using a novel, state-of-the-art multidose dry powder inhaler (MDPI), Genuair(R). Genuair(R) was ... registered trademark for the Multiple-Dose Dry powder Inhaler (MDPI) and is pending regulatory ...

Concomitant Treatment With Nebulized Formoterol Fumarate and Tiotropium Provides Clinically Significant Improvements for COPD Patients

... treatment with tiotropium bromide inhalation powder (TIO; Spiriva(R), 18mcg) administered with ... been previously available in the U.S. in a dry powder formulation with twenty years of ... -- nebulizers, metered-dose inhalers, and dry powder inhalers -- nebulizers require no special ...

Anesiva Announces Publication of Phase 3 Zingo(TM) Data in the Journal Pediatrics

... (lidocaine hydrochloride monohydrate) powder intradermal injection, the company's fast-acting, ... Cannulation Pain After Fast-Onset Needle-free powder Lidocaine or Placebo Treatment), demonstrated ... is a needle-free system that delivers lidocaine powder into the skin and provides analgesia in one to ...

Anesiva Announces Pivotal Phase 3 Trial of Zingo(TM) Meets Primary Endpoint and Significantly Reduces Venous Access Pain in Adults

... Zingo(TM) (lidocaine hydrochloride monohydrate) powder intradermal injection system compared to placebo ... system that delivers sterile lidocaine powder into the skin and provides topical, ... Zingo(TM) (lidocaine hydrochloride monohydrate) powder intradermal injection system, to reduce pain ...

Carrington Subsidiary DelSite Initiates Critical Toxicology Studies of Its Nasal Powder Bird Flu Vaccine

... Development Milestone - Novel, Nasal powder Vaccine Delivery Technology IRVING, Texas, Aug. ... animal toxicology studies of its GelVac(TM) nasal powder influenza vaccine, incorporating an H5N1 (bird ... I human safety study of the GelVac(TM) nasal powder H5N1 vaccine in late 2007. The toxicology studies ...

ASMANEX(R) (Mometasone Furoate Dry Powder Inhaler) Now Approved in Japan for the Treatment of Bronchial Asthma in Adult Patients

... received marketing approval for ASMANEX TWISTHALER (mometasone furoate dry powder inhaler) for the treatment of bronchial asthma in adults.(1) "We are ... inhaled corticosteroid to treat bronchial asthma in an innovative dry powder inhaler device," Koestler added. "Schering-Plough K.K. has received eight ...

ULURU Inc. to Present Altrazeal(TM) Clinical Evidence and Advanced Therapeutic Research at the Diabetic Foot Global Conference (DFCon) 2009

... diabetic foot ulcers is detailed in a poster titled "Properties of a Novel powder Wound Dressing and Clinical Experience in Diabetic Foot Ulcers." This work presents the use of Altrazeal(TM) Transforming powder Dressing in the treatment of four separate ulcers in diabetic patients. ...

Forest Laboratories, Inc. and Laboratorios Almirall, S.A. Provide an Update on the Aclidinium Bromide Clinical Development Program

... is administered to patients using a novel, state-of-the-art multidose dry powder inhaler (MDPI), Genuair(R)(2). Genuair(R) was designed with an intuitive ... is the proposed registered trademark for the Multiple-Dose Dry powder Inhaler (MDPI) and is pending regulatory approval. ...

American Dairy Provides Business Update

... of the leading producers and distributors of premium infant formula, milk powder and soybean, rice and walnut products in China, today provided a business ... of the leading producers and distributors of premium infant formula, milk powder and soybean, rice and walnut products in China. Feihe Dairy is ...

ProFibrix Steps up Recombinant Fibrinogen Program With PER.C6(R) License From Crucell

... is based on fibrinogen derived from human blood plasma and is a unique dry powder topical hemostat that stops acute and severe bleeding during surgery or ... is based on a mixture of fibrinogen and thrombin and is a unique dry powder topical tissue sealant that stops acute and severe bleeding after trauma ...

Clinical Trial Data on the Safety and Efficacy of Concomitant Formoterol Fumarate/ Tiotropium Treatment for COPD

... (LABA) that has been previously available in the U.S. in a dry powder formulation and has twenty years of worldwide experience. Perforomist(TM) ... to deliver bronchodilators -- nebulizers, metered-dose inhalers, and dry powder inhalers -- nebulizers require no special technique or coordination, as ...

Targanta Presents First Data Demonstrating In Vitro Activity and In Vivo Efficacy of Prodrugs in Osteomyelitis Models

... of bovine bone powder. Most were found to bind near quantitatively to bone powder and released the parent fluoroquinolone at various rates. In this in vitro study, the high affinity displayed by the compounds for bone powder and their ability to regenerate active parent compound over time suggests ...

MicroDose Announces Positive Results From the QDose Inhaled Insulin Glucose Clamp Study

... MicroDose's proprietary electronic inhaler technology and Vectura's dry powder insulin formulation. The QDose inhaled insulin product offers dose ... delivery technologies with generic drug substances. MicroDose's dry powder inhaler platform is a handheld, low cost, breath activated technology ...

Sosei and Vectura Announce Start of Phase III Clinical Study With NVA237

... NVA237, a once-daily, long-acting muscarinic antagonist (LAMA) for the treatment of chronic obstructive pulmonary disease (COPD). NVA237 is a dry powder formulation for oral inhalation of glycopyrronium bromide, a LAMA with a rapid onset of activity. The study has now appeared on clinicaltrials.gov ...

ProFibrix Initiates Phase II Clinical Trial of its Lead Topical Hemostat Product Fibrocaps(TM)

... before the end of 2009. Fibrocaps is based on a mixture of two essential blood clotting proteins, fibrinogen and thrombin, and is a unique dry powder topical tissue sealant that rapidly stops bleeding after or during surgery. Fibrocaps has major advantages over existing liquid tissue sealants: it ...

PARI Pharma's Nebulized DSCG Shows Results Similar to Inhaled Steroids in Asthma Studies Presented at ATS

... the hygroscopic nature [the ability to attract water molecules] of DSCG, and its tendency to grow in size upon inhalation when administered via a dry powder or metered dose inhaler (DPI or MDI). This assumption is supported by in-vitro study results previously published by PARI Pharma and other studies ...

Pharmaxis Announces Positive Results of Phase 3 Cystic Fibrosis Trial

... In a trial which recruited a wide range of patients with varying disease severity, Bronchitol showed significant health benefits. As the first dry powder formulation to publish positive results in cystic fibrosis it promises convenience for patients who have complex daily schedules dominated by ...

Optigenex Inc. Signs New License and Distribution Agreement With Itochu Corporation of Japan

... including harmful effects of UV radiation from over exposure to the sun, stress, environmental pollution and other toxins. In its standard bulk powder form, AC-11(R) supplement may be consumed orally or combined with liposomes and other delivery mechanisms for topical application on the skin. ...

Pharmaxis Announces New Drug Application Submission for Aridol(TM)

... Pharmaxis formally proposes that the FDA approve a new pharmaceutical for sale and marketing in the U.S. There is currently no FDA approved dry powder bronchial challenge test available in the U.S. and Aridol is the first test of this kind that comes complete and ready to use. Alan Robertson, ...

MannKind Reports Successful Completion of Device Bioequivalence Trial

... clinical trials in order to make the device more rugged and less costly to manufacture. Clinical trial subjects were administered AFRESA Inhalation powder from the same bulk lot, according to a randomized two-way crossover protocol, consistent with the standard requirements of bioequivalence testing. As ...

Plastic Surgeons Warn of Malnutrition in Body Contouring Patients

... the official medical journal of the American Society of Plastic Surgeons (ASPS). Optimizing nutrition with the addition of supplements, such as powder drinks and multi-vitamin tablets formulated for massive weight loss patients, is vital to successful body contouring surgery, the study reveals. ...

Nebulized Perforomist(TM) Inhalation Solution Provided Prolonged Bronchodilation and Increased Patient Satisfaction Compared to Albuterol/Ipratropium MDI

... 24 to 30 million. About Nebulization Of the three types of devices used to deliver bronchodilators - nebulizers, metered-dose inhalers, and dry powder inhalers - nebulizers require no special technique or coordination, as the medication is converted into a fine mist that the patient inhales through ...

Landmark COPD Trial UPLIFT(R) Shows SPIRIVA(R) HandiHaler(R) Sustained Lung Function Improvements Over Four Years

... capsule. Only use the HandiHaler device to take the SPIRIVA capsule. Do not use the HandiHaler to take any other medications. Do not get SPIRIVA powder in your eyes. The most common side effect with SPIRIVA is dry mouth. Others include constipation and problems passing urine. For a complete list of ...

Established Safety Profile of Spiriva Confirmed by 30 Rigorously Controlled Clinical Trials and the Landmark Trial UPLIFT

... capsule. Only use the HandiHaler device to take the Spiriva capsule. Do not use the HandiHaler to take any other medications. Do not get Spiriva powder in your eyes. The most common side effect with Spiriva is dry mouth. Others include constipation and problems passing urine. For a complete list of ...

Second Pivotal Phase 3 Trial In Cystic Fibrosis Begins

... in the lungs of patients with cystic fibrosis, bronchiectasis and chronic obstructive airway diseases. Bronchitol is a patented, inhalable dry powder formulation of mannitol that can be administered by a convenient, hand- held pocket sized device. Cystic fibrosis is a fatal disease, affecting more ...

MicroDose Technologies Announces Achievement of Phase I Clinical Milestone Triggering First Milestone Payment Under Collaboration with Merck & Co., Inc.

... Merck & Co., Inc., through a Merck affiliate, has been achieved, triggering the first payment under the global license agreement for MicroDose's dry powder inhaler (DPI) technology announced in March 2008. This milestone signals the initiation by Merck of a Phase I clinical study of an investigational ...

AstraZeneca Submits an sNDA for SYMBICORT(R) for the Treatment of Asthma in Children as Young as Age Six

... asthma previously treated with inhaled corticosteroid therapy.(3) In this study, SYMBICORT was compared to budesonide pMDI and formoterol dry powder inhaler.(3) A second study evaluating this dose included 351 subjects ages 6 to 11 years old.(4) Results from both studies demonstrated that ...

Study Analyzed SYMBICORT(R) in Children with Persistent Asthma

... symptoms, nighttime rescue medication use and rescue medication-free days in patients taking SYMBICORT compared to those taking formoterol dry powder inhaler (DPI) or budesonide pressurized metered-dose inhaler (pMDI). Results were presented today at the International Conference of the American ...

Concomitant Use of Nebulized Formoterol Fumarate and Tiotropium Provides Significant Improvement in Dyspnea, COPD Symptoms and Rescue Medication Use over Tiotropium Alone

... 24 to 30 million. About Nebulization Of the three types of devices used to deliver bronchodilators -- nebulizers, metered-dose inhalers, and dry powder inhalers -- nebulizers require no special technique or coordination, as the medication is converted into a fine mist that the patient inhales through ...

Forest and Almirall Announce Positive Results of Clinical Studies for Aclidinium Bromide, a Novel, Long-Acting Anticholinergic for the Treatment for COPD

... tiotropium (18 mcg) arm was included as an active control. The study demonstrated aclidinium (200 mcg and 400 mcg), administered via a multi-dose dry powder inhaler, significantly increased trough (24-hour) forced expiratory volume in one second (FEV1) -- an important measure of lung function -- on Day 29 ...

Annual Conference on Vaccine Research to Highlight Not Only Health Benefits But Also Economic Gains

... for each pathogen. These are the first results to show efficacy with one vaccine against all four pathogens. The vaccine has been constituted as a powder allowing for long shelf life, stability at different temperatures and administration in a variety of ways including subcutaneous injection and as a ...

Dr. Peter Nash, Ph.D. Joins Mach One Corporation as Chief Scientist

... ), the company currently manufactures and sells Immunogam (TM) , a colostrums replacement, supplement and prophylactic, in sterile powder form, which can be administered orally or intravenously. VDx is also further developing a proprietary procedure to allow for large scale ...

U.S. Food and Drug Administration Approves ORENCIA(R) (abatacept) for the Treatment of Moderate-to-Severe Polyarticular Juvenile Idiopathic Arthritis (JIA) in Patients Six Years and Older

... is not recommended for use concomitantly with other biologic RA therapy, such as anakinra. For adult patients with RA, ORENCIA, a lyophilized powder for intravenous infusion, should be administered by a healthcare professional as a 30-minute intravenous infusion at a fixed dose based on body ...