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Peptides in Medical Technology

Raptor Pharmaceuticals Receives Notices of Allowance for Two NeuroTrans(TM) Patent Applications

... generally cover the use of its proprietary RAP peptides in the delivery of diagnostic and therapeutic ... minimally invasive way by conjugating them to RAP peptides engineered by Raptor. Hundreds of ... the use of our NeuroTrans(TM) CNS targeting peptides and the extensive range of potential uses of ...

First Candidate from Esperance's Targeted Anti-cancer Platform, EP-100, Establishes Preclinical Proof of Concept

... a robust portfolio of small, novel oncolytic peptides to selectively destroy cancer cells that express ... on their surfaces. The positively charged peptides disrupt the negatively charged membranes of the ... These drug candidates, called membrane-disrupting peptides (MDPs), selectively kill cancer cells, including ...

Are Muramyl Peptides the Magic Bullet in Probiotics?

... effects of lysed probiotics are due to muramyl peptides in the cell fragments. "European doctors went ... a new bio-technology. In simple terms, muramyl peptides regulate the correlation between different ... system. When probiotics are lysed, the muramyl peptides become bio-available. The ...

Raptor Pharmaceuticals Provides Update of Product Programs

... first year of the collaboration, a number of RAP peptides were tested for their ability to cross the BBB. ... HepTide(TM) utilizes engineered RAP-based peptides conjugated to drugs to target their delivery to ... In neurodegenerative diseases, engineered RAP peptides called NeuroTrans(TM) are currently undergoing ...

Replikins LLC Finds West Nile Virus Replikin Count Has Reached Its Highest Recorded Value

... has discovered a new group of virus structural peptides within virus proteins, called replikins, ... measures the concentration of these specific peptides in virus proteins (Replikin Count(TM)). ... to come. Replikins LLC analysis of the West Nile peptides has provided advanced warning of the increase of ...

Radius' Investigational Bone Anabolic Agent, BA058, Increased Bone Mineral Density (BMD) at Key Fracture Sites in Phase 2 Clinical Trial in Postmenopausal Osteoporosis

... PTHrP (parathyroid hormone-related protein) and its analogs are critical peptides for promoting new bone formation. Though they act through the same ... play an important role in regulating bone remodeling in adults. While both peptides have demonstrated the ability to increase bone mineral density and bone ...

Swine Flu (H1N1) Infectivity to Increase Markedly and Lethality to Remain Low According to Latest Replikin* Peptide Genomic Data

... are based upon the company's discovery of replikins, a new group of peptides related to the rapid replication function in viral and other diseases. The ... predictive tools are based on the company's discovery of a new group of peptides related to rapid replication called Replikins, whose increase in ...

Intarcia Therapeutics, Inc. Announces Completion of Enrollment of ITCA 650 Phase 1b Study for the Treatment of Type 2 Diabetes

... technology that maintains stability of therapeutic proteins and peptides at human body temperature for extended periods of time. Exenatide, the ... edge are demonstrated by its abilities to stabilize proteins and peptides at above body temperature and to deliver them in a constant and consistent ...

Photos: Peptides Discovered to Alleviate Chemotherapy Side Effects

... After years of research, scientists at OncoNutrition(TM) have discovered peptides found in cow's milk that stimulate the body's own production of ... also increases ghrelin production, we were elated." The milk-based peptides in AminoAct(TM) are unlocked through a proprietary technology, and do not ...

Raptor Pharmaceuticals Provides Update on Targeting Platforms

... of RAP-based targeting platforms and potential therapeutics. RAP-based peptides engineered to withstand certain conditions, such as low pH, may bind better and demonstrate enhanced biological potency compared to proteins or peptides derived from the naturally occurring RAP sequence and will complement our ...

Raptor Pharmaceuticals Corp. Initiates Phase IIa Clinical Study for Convivia(TM)

... diseases. HepTide(TM) is designed to utilize engineered RAP-based peptides conjugated to drugs to target their delivery to the liver to potentially ... liver cancer and hepatitis. In neurodegenerative diseases, engineered RAP peptides called NeuroTrans(TM) are currently undergoing evaluation at Stanford ...

DSM Obtains Exclusive World-Wide License for Innovative Drug Delivery Technology

... rate and duration of release of their therapeutic payload. The technology can be used with a diverse group of drug candidates, from proteins, peptides and nucleic acids to small molecule drugs, thus expanding the possible application areas of DSM's Trancerta(R) platform. The license DSM obtained ...

FDA Submission of B-R-A-H-M-S MR-proANP Kryptor

... Kryptor Test. Atrial Natriuretic Peptide (ANP) is predominantly produced in the atrium of the heart and comprises 98% of the natriuretic peptides in the circulation. ANP is involved in natriuresis, diuresis, vasodilation and cardiovascular homeostasis. Although this peptide is unstable, ...

Adlyfe Strikes Translational Medicine Partnership With Wyeth Pharmaceuticals for Alzheimer's Biomarker Assay

... plaque formation). These aggregates are associated with disease state progression in a number of brain-wasting and amyloid diseases. Pronucleon(TM) peptides have also been shown to cross the blood brain barrier when administered intravenously in animals and image amyloid aggregates in the brain. ...

Novel Product for Post Surgical Scar Formation Entering Clinical Development

... treatment for preventing harmful scarring and promoting wound healing after surgery. PharmaSurgics product concept is based on proprietary synthetic peptides which have strong anti-inflammatory and anti-infectious properties. The company was founded in 2005, based on extensive research by Dr. Inger ...

Long-term Follow Up Interim Data Show Nplate(TM) Increased and Sustained Platelet Counts in Adult Chronic ITP Patients

... chronic ITP. About Nplate Nplate, Amgen's first peptibody, is a novel engineered therapeutic fusion protein with attributes of both peptides and antibodies, but is distinct from each. Nplate works similarly to thrombopoietin (TPO), a natural protein in the body. Nplate stimulates the TPO ...

Nplate(TM) (Romiplostim) Receives Positive Opinion for Marketing Authorisation in the European Union

... life threatening. Nplate, a thrombopoietin (TPO) mimetic, is a novel engineered therapeutic fusion protein with attributes of both peptides and antibodies, but is distinct from each. Nplate works similarly to TPO, a natural protein in the body. Nplate stimulates the TPO receptor, which ...

Lytix Presents LTX-109 Anti-Microbial Data at ICAAC

... infections, as well as first-in-class oncology treatments. Lytix was established in 2003 to commercialise world-class research in the field of lytic peptides spun out by the founding scientists working in the University Hospital and University of Tromso in Norway. Operating out of a main office ...

Critical Pharmaceuticals Enter Sustained Release hGH Arena

... a Nottingham UK-based biotechnology company with proprietary drug delivery technologies for the sustained release and nasal delivery of proteins and peptides and labile or insoluble small molecules. Critical Pharmaceuticals was founded by Professor Steve Howdle in 2002 based on his world leading research ...

InNexus Lead Candidate DXL625 Outperforms Rituxan in Additional Animal Studies

... positioned to begin formal discussions with the FDA." About DXL(TM) Technology Platform DXL(TM) technology works by integrating self-binding peptides into monoclonal antibodies, potentiating target binding. Modified antibodies "cluster" upon engaging the target receptor site, resulting in ...

Favourable Six Months Follow-Up Results From Intercell's Phase II Therapeutic Hepatitis C Program

... patients. As previously reported in February 2008, in this trial the therapeutic Hepatitis C vaccine (IC41) comprising five synthetic T-cell peptides and Intercell's first-generation poly-Arginine adjuvant (IC30) disclosed a statistically significant reduction of viral load in the blood ...

Debiopharm and EPFL Sign Research Project Agreement to Identify Inhibitors of Signalling Pathways Controlling Cell Fate for Cancer Treatment

... signature of a research project with the Ecole Polytechnique Federale de Lausanne (EPFL), aimed at the identification of novel small molecules and peptides that interfere with pathways controlling cell fate specification. The project, named Debio 0826, could lead to the development of potential ...

Emisphere Announces Data From Independent Clinical Study of Effects of Oral GLP-1 on Glucose and Insulin Concentrations

... application of GLP-1 is cumbersome and impractical for chronic treatment regimens. Oral application of peptides is, however, difficult as peptides have a low oral bioavailability due to their molecular size and physico-chemical characteristics," said Prof. Beglinger. "Emisphere's oral delivery ...

Lilly and TransPharma Medical Announce Licensing and Development Agreement

... solution that enables the safe, reproducible and accurate delivery of a broad range of product candidates, including hydrophilic small molecules peptides and proteins. About Osteoporosis Osteoporosis is a debilitating disease that affects an estimated 75 million people in Europe, the U.S. and ....

Roche Moves Investigational Diabetes Drug, Taspoglutide, Into Phase III Clinical Trials

... controlled release properties. Ipsen is the originator of the concept of excipient free sustained release formulation applied to therapeutic peptides and proteins. Taspoglutide is being developed as a novel and innovative treatment for patients with type 2 diabetes mellitus, the fourth leading ...

Omega 3 Fatty Acids Bound to Phospholipids has Potential Benefit for Attention-Deficit Hyperactivity Disorder (ADHD)

... distributed exclusively in the United States by EuroPharma Inc, is a whole food omega-3 EPA/DHA complex which includes phospholipids and marine peptides as they naturally occur in salmon. Molecularly different from other omega-3's on the market, Vectomega(R) is said to be up to 10 to 50 times more ...

PharmAthene's Recombinant Butyrylcholinesterase (rBChE) May Play A Neuroprotective Role in Alzheimer's Disease

... part of the collaboration with Hebrew University, PharmAthene has an exclusive, worldwide license to the application of rBChE and its corresponding peptides for use in the field of Alzheimer's disease. About Protexia(R): Recombinant Human Butyrylcholinesterase (rBChE) Protexia is a pegylated form of ...

Neurobiological Technologies, Inc. and Buck Institute Partner to Develop Novel Treatment for Alzheimer's Disease

... the Buck are focused on a naturally occurring protein that has been shown in both cell culture and mice to inhibit the production of amyloid-B (AB) peptides while simultaneously facilitating the growth and preservation of nerve fibers in the brain. As part of this agreement, Neurobiological Technologies ...

Study Shows: New Blood Test Proven Six Times More Effective For Tuberculosis Control

... of a cell mediated immune response in TB-infected individuals. The T-cells of these individuals are sensitized to TB, and respond to stimulation with peptides simulating those expressed by the TB causing bacteria, secreting a cytokine called interferon-a. QFT accurately measures the interferon-a response in ...

Mersana Therapeutics Reports Phase I Results for XMT-1001 in Patients with Solid Tumors at AACR-NCI-EORTC International Conference

... platform. Fleximer is a novel, biodegradable and bio-inert polymer that can be chemically linked to drugs, including small chemical entities, peptides and biologics. Fleximer-based compounds can be individually designed to improve the therapeutic performance of drugs by modulating such properties as ...

Adlyfe Study on the Detection of Misfolded Proteins Published in the Journal Transfusion

... tests for amyloid diseases to the use of postmortem tissue. Adlyfe's novel technology is based on the synthesis of conformationally sensitive peptides (chains of amino acids that are smaller than proteins) which are created to target specific protein shapes associated with various diseases. The ...

Preclinical Data on Cytogen's Technology to be Reported at the AACR Annual Meeting

... random phage libraries: Epitope-specific peptides recapitulate antibody complementarity ... PSMA and MUC-1 antibodies and PSMA binding peptides target prostate xenografts. Presentation ... nanoparticles coated with active-transport peptides derived from phage libraries. The abstracts are ...

Helix BioMedix to Discuss Potential of Its Proprietary Peptides at the BIO International Convention

... peptides. These 'new generation' peptides are excellent drug candidates due to their low ... fungal infection models. Helix BioMedix's peptides are also currently bringing value-added ... leaders and skin care clinicians are identifying peptides as the next generation of cosmetic skin care ...

Opexa Presents Tovaxin Research at Federation of Clinical Immunology Societies Annual Meeting

... entitled "Identifying New Immunodominant Myelin peptides in Relapsing Remitting Multiple Sclerosis ... allowed Opexa to identify several myelin protein peptides from myelin basic protein (MBP), ... as being immunodominant, including some peptides never before reported, and others as being ...

Ceragenix Compound Shows Promise for Treating Lethal Cystic Fibrosis Infections

... effective than positively charged antibacterial peptides (LL-37) against a multidrug resistant strain of ... the presence of naturally occurring antimicrobial peptides such as LL-37 found in the lung fluid which form ... to the invaders' membranes, the antimicrobial peptides permeabilize and destroy the bacterial membranes ...

Generex Biotechnology Vaccine Strategy Presented at International Conference in London

... Company is currently conducting a Phase II clinical trial of one of its peptides in breast cancer patients and a Phase I trial in volunteers of other peptides for the potentially pandemic H5N1 avian influenza. In both of these ...

Ambrilia Highlights Encouraging Data for its HIV Integrase Inhibitor Program and Recent Developments at Annual Meeting

... a biopharmaceutical company developing novel small molecules and peptides to treat infectious diseases and cancer, held its Annual General and ... is a biopharmaceutical company developing novel small molecules and peptides to treat infectious diseases and cancer. Ambrilia's product portfolio ...

New Flu Vaccine From PepTcell Could Provide Immunity Against All Strains of Influenza Virus

... sequences in Flu-V are highly conserved across strains, and that these peptides are naturally presented on the surface of flu-infected cells, and ... Gregory A Stoloff, Wilson Caparros-Wanderly: Synthetic multiepitope peptides identified in silico induce protective immunity against multiple influenza ...

New Flu Vaccine from PepTcell Could Provide Immunity Against All Strains of Influenza Virus

... sequences in Flu-V are highly conserved across strains, and that these peptides are naturally presented on the surface of flu-infected cells, and ... Gregory A Stoloff, Wilson Caparros-Wanderly: Synthetic multiepitope peptides identified in silico induce protective immunity against multiple influenza ...
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(Date:11/30/2009)...a colorless and odorless radioactive gas that is p... is a product of uranium decay and is found in tra...nd groundwater as well as building materials, plan...tration is expressed as the amount of radiation th...s in a liter of air; thus the units are picocuries...
(Date:11/26/2009)...have at last worked out a way of using recordings ... populations. This is the first time sound recordi...nto accurate estimates of bird species, population...ish Ecological Society,s Journal of Applied Ecolo... to a major advance in our ability to monitor whal...
(Date:11/26/2009)...erg, 27 November 2009 What are the bare essential...to produce a cell that can survive on its own? Can...understand how an entire organism functions as a s...cientists in a partnership between the European Mo...ermany, and the Centre de Regulacio Genmica (CRG) ...
Breaking Biology News(10 mins):Health Physics Society recommends considering action for indoor radon below current guidelines 2Ecologists sound out new solution for monitoring cryptic species 2First-ever blueprint of a minimal cell is more complex than expected 2First-ever blueprint of a minimal cell is more complex than expected 3New Mobile STAR Cranial Center of Excellence Vehicle Brings Cutting Edge Treatment to Satellite Communities 56758 1New Mobile STAR Cranial Center of Excellence Vehicle Brings Cutting Edge Treatment to Satellite Communities 56758 2New Mobile STAR Cranial Center of Excellence Vehicle Brings Cutting Edge Treatment to Satellite Communities 56758 3New Mobile STAR Cranial Center of Excellence Vehicle Brings Cutting Edge Treatment to Satellite Communities 56758 4New Mobile STAR Cranial Center of Excellence Vehicle Brings Cutting Edge Treatment to Satellite Communities 56758 5Tetraphase Presents Study Results for Novel Classes of Antibiotics from its Breakthrough Synthetic Chemistry Platform at ICAAC 2009 13979 1Tetraphase Presents Study Results for Novel Classes of Antibiotics from its Breakthrough Synthetic Chemistry Platform at ICAAC 2009 13979 2Video 3A U S Department of Health and Human Services Joins Ad Council and Warner Bros Pictures to Combat Childhood Overweight and Obesity 56755 1Video 3A U S Department of Health and Human Services Joins Ad Council and Warner Bros Pictures to Combat Childhood Overweight and Obesity 56755 2Video 3A U S Department of Health and Human Services Joins Ad Council and Warner Bros Pictures to Combat Childhood Overweight and Obesity 56755 3Video 3A U S Department of Health and Human Services Joins Ad Council and Warner Bros Pictures to Combat Childhood Overweight and Obesity 56755 4Video 3A U S Department of Health and Human Services Joins Ad Council and Warner Bros Pictures to Combat Childhood Overweight and Obesity 56755 5
(Date:11/30/2009)..., CHICAGO, Dec. 1 A study using ...aluate brain function revealed that adults who wer...n injury. The results were presented today at the ...h America (RSNA). ,, "What we have found is tha...ure," said the study,s lead author, Kim Cecil, Ph....
(Date:11/30/2009)... , WAYNE, Pa., Nov. 30 /PRNewswire-FirstCall/... WKN: A0YCND) has elected William "Bill" R. Field...Fields, age 59, is Chairman of Intersource Co. Ltd...l, Inc. Previously, Mr. Fields served as Chairman ... Inc. from 2002 to 2003, President and Chief Execu...
(Date:11/30/2009)... , ATLANTA, Nov. 30 Kool Smi...Initiative," with national recognition as one of...by Chief Technical Architect, Mark Blomquist, Kool...ure to support the electronic health records syste...es. With this roll-out now complete, Kool Smiles ...
(Date:11/30/2009)..., IRVINE, Calif., Nov. 30 A revo...s, referring physicians, and patients with seamles...ts with just the click of a button was announced t... providers of image management, visualization and ...workflow and doing away with the cumbersome and co...
(Date:11/30/2009)...ess radiation dose was equivalent to 113 chest X-r...althDay News) -- More than half of patients who ha...necessary imaging tests that expose them to extra ..., 978 CT abdominal and pelvic series were performe...of the patients were 30 to 50 years of age. The re...
Breaking Medicine News(10 mins):Health News:Childhood Lead Exposure Causes Permanent Brain Damage 2Health News:Childhood Lead Exposure Causes Permanent Brain Damage 3Health News:VitaminSpice Elects Bill Fields to the Board of Directors 2Health News:Kool Smiles Named Among 2009 InfoWorld 100 2Health News:Candelis Announces Revolutionary Cloud-Hosted Data Services 2Health News:Candelis Announces Revolutionary Cloud-Hosted Data Services 3Health News:CT Scan Patients May Get Unnecessary Imaging 2
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