Pathogen in Medical Technology

Pivotal Phase III Data Confirm the Efficacy and Safety of Arpida's Intravenous Iclaprim in Treating Patients With Complicated Skin and Skin Structure Infections

... ITT population who had an infecting Gram-positive pathogen isolated at baseline; -- The PP population ... as clinical failures. The causative pathogen distribution in the study population was ... aureus (S. aureus) as the predominant pathogen isolated at baseline (76.5 percent for ...

Rapid Test for Pathogens Developed By K-State Researchers Could Be Used to Detect Diseases Used By Bioterrorists

... out the specific genetic markers that set one pathogen apart from another and determine antibiotic ... be to develop a test that indicates how much of a pathogen is present, or rather how bad an infection is. ... days to isolate and identify each individual pathogen and generate their antimicrobial resistance ...

Pew Commission Says Industrial Scale Farm Animal Production Poses 'Unacceptable' Risks to Public Health, Environment

... employed in the system, increase pathogen risks and magnify opportunities for transmission ... prolonged worker contact with animals, increased pathogen transmission within a herd or flock, and the ... for food animals, and that stress can increase pathogen shedding in animals. Rural America Life ...

FreshFx Recognized for use in the Scalder as a Solution to the 'Yield/Pathogen Reduction Dilemma'

... of FreshFx solution used for OLR, then for pathogen control at the New York rinse and pickers, could ... About SteriFx SteriFx, Inc. provides pathogen control systems dedicated to reducing or ... offer a safe and revolutionary process for pathogen elimination for the food industry. Last month, ...

AdvanDx Launches Fast, 90 Minutes Protocol for All CE-IVD Marked PNA FISH(R) Tests in Europe

... pathogen Identification Results in 90 Minutes Direct from Positive Blood Cultures ... have shown that implementing PNA FISH tests reduced time to reporting of pathogen identification results by up to 48-72 hours, improved antibiotic selection ...

Mpex Pharmaceuticals Presents New Data on MP-376 in Cystic Fibrosis

... positive for P. aeruginosa at baseline. P. aeruginosa is a bacterial pathogen that is a leading cause of morbidity in CF patients. The great majority of CF patients over the age of 18 are chronically infected with this pathogen and chronic infection has been shown to lead to acute exacerbations and ...

Successful Results for Mymetics Corporation's Mucosal HIV/AIDS Vaccine Viral Challenge Significantly Exceeds Expectations

... on eliciting immune protection capable of interfering with late events of pathogen transmission, a generally accepted approach coupled, uniquely and most importantly, with early events of pathogen transmission, such as preventing virus entry across the mucosal tissues, ...

Vical Advances RapidResponse(TM) DNA Vaccine Platform Under $6 Million Grant from NIH

... disease such as influenza or SARS, an accidental release of a dangerous pathogen such as Ebola virus or Yersinia pestis (plague bacterium) from a ... or an intentional release of a weaponized or bioterrorist-modified pathogen designed to cause diseases such as anthrax or smallpox. Initial research ...

DuPont and USDA ARS to Collaborate on New E. coli Test in Beef

... Neb., and DuPont Qualicon will develop a new test for E. coli 0157:H7, a pathogen that led to more than 30 million pounds of ground beef being recalled in ... president -- DuPont Qualicon, said. E. coli O157:H7 is a food borne pathogen usually associated with eating undercooked, contaminated ground beef. Even ...

Trius Announces Positive Results From Phase 2 Clinical Trial of Torezolid in Patients With Complicated Skin and Skin Structure Infections

... at the late follow-up visit 21-28 days post treatment. Highlighting the growing problem of drug resistance in the community, MRSA was the primary pathogen in 72% of the microbiologically evaluable patients. "I was impressed by the rapid clinical effect of oral torezolid in curing severe skin ...

TriLink BioTechnologies, Inc. Announces Supply Agreement With Osmetech Molecular Diagnostics

... warfarin panel with the proprietary 4F2 marker, a venous thrombosis panel (Factor II, Factor V Leiden and MTHFR) and a RESPLEX(R) respiratory pathogen assay marketed in collaboration with Qiagen that is capable of detecting Swine Flu. For more information about the company and products, call (800) ...

Parasites That Live Inside Cells Use Loophole to Thwart Immune System

... insights. It reaffirms the notion that pathogens have an incredibly diverse way of manipulating their hosts. And it reveals a new pathway by which a pathogen can induce an enzyme that is normally not present in those macrophages and use the induction of that enzyme to its advantage." Murray emphasized ...

Doctor Declares War on Hospital Infections, Patents MRSA-Killing Machine

... to destroy virus, bacteria and spores within both line-of-site and primary shadow behind bed rails, door knobs and IV poles. TRU-D disinfected every pathogen on every surface, every time," said Deal. Clinical trials demonstrated that TRU-D destroyed the biological contaminates that cause MRSA, C. diff, ...

First Molecular Tem-PCR Test to Identify Multiple Forms of Staph and MRSA Obtains CLIA Certificate

... available for advanced research. Dr. Han overcame the limitations of traditional Real Time PCR (RT-PCR) technology, a test that can only identify one pathogen at a time. Another limitation of RT-PCR is that it does not identify the differentiation between the pathogens and/or their various strains in ...

Study Shows Use of AdvanDx's PNA FISH(TM) Test was Associated with an 82% Reduction in Intensive Care Unit Mortality Rates from Staphylococcus aureus Bloodstream Infections

... of the patient's blood (i.e. a blood culture) turns positive with bacteria and yeast. Rapid and accurate identification of the specific infecting pathogen is crucial to ensure early and appropriate therapy and save patient lives. About PNA FISH(TM) PNA FISH is an easy-to-use and highly sensitive and ...

Forest Laboratories Announces Positive Results from Phase III Clinical Studies of Ceftaroline for the Treatment of Complicated Skin and Skin Structure Infections

... adult patients (702 CANVAS I and 694 CANVAS II), with cSSSI caused by gram-positive and gram-negative bacteria. Over 30% of patients with a confirmed pathogen had a MRSA infection. Ceftaroline was statistically proven non-inferior to the combination of vancomycin plus aztreonam. Ceftaroline treated ...

AdvanDx Submits Yeast Traffic Light PNA FISH(TM) for FDA 510(k) Clearance for Detection of Candida species in Positive Blood Cultures

... of the patient's blood, i.e. a blood culture, turns positive with bacteria and yeast. Rapid and accurate identification of the specific infecting pathogen is crucial to ensure early and appropriate therapy and save patient lives. About PNA FISH(TM) PNA FISH is an easy-to-use and highly sensitive and ...

Quigley Announces Successful Poultry Study of Chickens With Infectious Bronchitis; Plans to Approach the Poultry Industry for Potential Commercialization

... Infectious Bronchitis Virus (IBV). The data from the study indicated that QR448(a) is efficacious against an IBV challenge in two week old specific pathogen free (SPF) chicks, confirming previous results indicating that treatment with QR448(a) before or after viral exposure has the potential to lessen or ...

PARI's eFlow Delivers Alnylam RNAi Therapeutic in Phase II Study

... is the most common cause for infant hospitalization (more than 100,000 hospitalizations annually in the U.S.), and the virus is a significant pathogen in the elderly. The RNAi therapeutic agent ALN-RSV01 is a small interfering ribonucleic acid (siRNA) targeting the messenger RNA of the RSV N gene ...

Researchers Identify Virus Possibly Responsible for Declining Honeybee Population Using 454 Sequencing Technology from Roche

... School of Public Health, and colleagues sequenced DNA and RNA samples that were extracted from collapsing and healthy bee colonies in search of any pathogen responsible for the collapse. The research identified five major bacterial groups, four lineages of fungi and seven types of viruses. While most of ...

Baxter Awarded Pandemic Advanced Supply Contract from the Department of Health

... and seasonal influenza vaccines in the United States. Baxter's candidate vaccine's antigen composition and structure closely resembles the actual pathogen circulating in nature. The candidate vaccine induces an immune response that is similar to the body's defense against a natural virus, without the ...

Vaxiion Researchers Discover Novel Vaccine Delivery System in Collaboration with San Diego State University

... paper was published today, in the March 8th issue. While most vaccines contain live micro-organisms, the 'minicell' vaccine studied mimics the live pathogen response without any risk of infection, making it particularly useful for immunizing children, the elderly and those with compromised immune ...

Arpida Announces Promising Results of "First-In-Man" Studies With AR-709

... activity against streptococci in general and, importantly, against multi-drug resistant Streptococcus pneumoniae, the most relevant pathogen in community-acquired pneumonia. Moreover the compound has been shown to be highly effective in preclinical pneumonia models of infection both ...

Baxter Announces Final Phase I/II Data and Initiation of Phase III Clinical Trial for Candidate Pandemic H5N1 Influenza Vaccine

... Baxter's candidate H5N1 vaccine is derived from H5N1 strain A/Vietnam/1203/2004. Its antigen composition and structure closely resembles the actual pathogen circulating in nature. The candidate vaccine induces an immune response (both cell and antibody mediated) that is similar to the body's defense ...

Scientific Results Presented At ECCMID Demonstrate Well- Differentiated Profile of Basilea's Two Phase III Anti- infective Compounds

... against several strains of Aspergillus fumigatus including an itraconazole-resistant strain (P1951). Aspergillus fumigatus is the most frequent pathogen among the difficult-to-treat invasive mould infections. Poster P987 showed that isavuconazole is completely bioavailable, supporting early switch ...

New Report Illuminates Ampligen's Unique Mechanism of Action

... such as otherwise lethal viruses and even various forms of cancer. When the dormant alarm signals of TLRs are activated (as by exposure to a pathogen or a stimulant agent such as Ampligen(R)), TLRs in effect cause an overreaction, driving the body to proliferate broad-spectrum defenses against many ...

Pacgen Announces Positive Results from Phase I/II Trial of Novel Antifungal Drug

... effect, increasing the cure rate and reducing the time to relapse. About Candida Infection Candida albicans is the most common fungal pathogen among immune-compromised, hospitalized patients, accounting for roughly 50-60% of all bloodstream fungal isolates. Opportunistic growth of Candida ...

Near-Patient Testing: The Advantages of C-Reactive Protein in Hematological Testing

... of onset ( e.g. during leukemia induction therapy, which may be associated with a pre-existing infection), and fever monitoring, associated with pathogen identification in only 25-30% of these cases, leading to emergency requirements in some instances. Based on solid clinical analysis and a few simple ...