pandemic

Avian (Bird) Flu: Is There a Role for Rapid Tests?

...e to the H5N1 subtype, infections could then reach pandemic proportions. This is particularly worrisome since the observed case fatality rate for human H5N1 infections has been over 50%. Furthermore, the H5N1 subtype shows resistance to two mainstays of influenza therapy, amantadine and rimantadine. While ...

Pharmexa A/S (DK) - Pharmexa presents data from influenza program

..." influenza virus vaccine against bothseasonal and pandemic viral strains. Mark Newman, Ph.D., SVP, Global R&D Laboratories, noted:"These data are very promising and important to us for two reasons.First, we were able to demonstrate protection of the HLA transgenicmice from lethal influenza virus chall...

New Flu Vaccine from PepTcell Could Provide Immunity Against All Strains of Influenza Virus

...rotect against all strains of influenza, including pandemic andannual, was presented today by PepTcell, at the...potential to provide effective protectionagainst a pandemic flu strain by enabling stockpiling and theinitiation of a worldwide vaccination program ahead of ano...

New Flu Vaccine From PepTcell Could Provide Immunity Against All Strains of Influenza Virus

...potential to provide effective protectionagainst a pandemic flu strain by enabling stockpiling and theinitiati...fective against allstrains of flu virus, including pandemic strains. Current flu vaccines only work against specific virus strains.As these strains mutate freq...

GenVec Announces Update of Safety and Efficacy Data from Pivotal Phase II/III PACT Study of TNFerade at ASCO

...espiratory syncytial virus (RSV), and seasonal and pandemic flu.Additional information about GenVec is available at www.genvec.comand in the Company's various filings with the Securities andExchange Commission. Statements herein relating to future financial or businessperformance, conditions or strategies an...

Novavax Pandemic Flu Vaccine Provided Protection Against a Lethal Challenge of Live Virus, Pre-Clinical Data Show

...wire-FirstCall/ -- Very low doses ofNovavax Inc.'s pandemic influenza vaccine provided protectionagainst a let... seasonalinfluenza vaccine is 15 micrograms. Other pandemic vaccines with noadjuvant have shown only modest levels of immunogenicity in humanswith doses as high...

Hemispherx Presents Potential Avian Influenza Treatment Breakthrough at Paris Conference

... demonstration of efficacy. "The threat of global pandemic illness from infectious diseaseputs the highest possible priority on finding therapeuticstrategies that can protect first responders and save patientlives," commented Dr. William Carter, Chairman and Chief ExecutiveOfficer of Hemispherx. "We are enco...

Iomai to Announce Results From Phase 1 Influenza Trial and Host Webcast Tomorrow

...dates in development:three targeting influenza and pandemic flu and one to prevent E.coli-related travelers' diarrhea. For more information on Iomai,please visit <a target="_blank" href="http://www.iomai.com/">http://www.iomai.com . CONTACT: Russell P. Wilson, Senior Vice President, ChiefFinancial Of...

CEL-SCI'S CEL-1000 Shown to Significantly Enhance Immune Response Against Avian Flu Antigen in Animals

...red forprotective immunity), and to biodefense and pandemic settings foranti-infectious vaccines. CEL-1000 has previously been shown to increase the antigenicityof hepatitis B virus (HBV). In challenge studies, CEL-1000 has alsopreviously been shown to protect animals against infection againstviruses and unr...

VGX Pharmaceuticals' Novel HIV and Pandemic Influenza DNA Vaccine Candidates Trigger Robust Immune Responses and Protection in Pre-Clinical Models

...SS WIRE)--May 23, 2007 - VGX Pharmaceuticals'novel pandemic influenza vaccine candidates triggered protectiveimmune responses in pre-clinical challenge studies, according todata presented for the first time today at the Third InternationalConference on DNA Vaccines in Malaga, Spain. VGX scientists created fou...

Vical's Vaxfectin Adjuvant With Needle-free Delivery Enhances DNA Vaccine Performance; Yields Antibody Responses Comparable to Electroporation Without Tolerability Issues

...sting ofa Vaxfectin(TM)-formulated DNA vaccine for pandemic influenza,anticipated in the second half of 2007, and to continuedexploration of Vaxfectin(TM)'s use in optimizing efficacy andsafety for future prophylactic or therapeutic applications." Both studies were conducted in rabbits with DNA vaccinesenc...

IR BioSciences Announces Promising Data from Study of Its Compound Homspera

...tem responsiveness tovaccines for diseases such as pandemic avian influenza, seasonalinfluenza, and perhaps ot... the World Health Organization notes,when the next pandemic virus strain emerges, it could circle theglobe in three months and cause significant morbidity andmo...

Novavax Reports Positive Pre-Clinical Study Results from Live Virus Challenge to Pandemic Flu Vaccine

...avax is developing vaccines to protectagainst H5N1 pandemic influenza, seasonal flu and other viraldiseases. Novavax's particulate vaccines closely matchdisease-causing viruses while lacking the genetic material to causedisease, which provides potential for greater immune protection atlower doses than current...

Peramivir Protects Mice From Lethal H5N1 Infection

... the use of this drug tocontrol influenza during a pandemic MEMPHIS, Tenn., May 01, 2007 /PRNewswire-USNewswir... might offer humans significant protectionduring a pandemic of the avian influenza virus H5N1, according toresults of mouse studies conducted by investigators a...

AVI BioPharma Reports Positive Pre-Clinical Influenza Data

...nd cause disease in humans. The current influenza pandemic in birds throughout Asia, EasternEurope and Turkey is caused by the H5N1 subtype. It is thought thatco-infection of humans or certain animals (such as pigs) with bothH1N1 and H5N1 can lead to a reassortment or recombination of viralparticles, resulti...

Iomai Dose-Ranging Trial Demonstrates Needle-Free Patch Vaccine for Travelers' Diarrhea Stimulates Immune Response Even at Low Doses

...studies of theIomai booster patch for seasonal and pandemic influenza." Travelers' diarrhea sickens between...idates in development:four targeting influenza and pandemic flu and one to prevent E.coli-related travelers' diarrhea. For more information on Iomai,please visi...

GenVec Announces New Research at AACR on Selectivity and Mechanism of Action of TNF-Based Anti-Cancer Therapy

..., malaria, foot-and-mouth disease,and seasonal and pandemic flu. Additional information about GenVecis available at www.genvec.com and in the Company's various filingswith the Securities and Exchange Commission. Statements herein relating to future financial or businessperformance, conditions or strategies a...

Vical's Vaxfectin Adjuvant Achieves Dose-Sparing Effect With Seasonal Influenza Vaccine

...tial to ease the anticipatedshortage of stockpiled pandemic influenza vaccine and the limitedglobal vaccine ma...-sparing effectwith the government-stockpiled H5N1 pandemic influenza vaccine,also produced by sanofi pasteur. Since neither Fluzone(R) nor thesanofi pasteur H5...

Rapid Response was Crucial to Containing the 1918 Flu Pandemic

...istent riddles of thedeadly 1918 Spanish influenza pandemic is why it struck differentcities with varying seve...suggest that a primary lesson of the 1918influenza pandemic is that it is critical to intervene early, saysAnthony S. Fauci, M.D., director of NIHs National Ins...

Novavax Vaccine Provides Robust Immune Response, Pre-Clinical Data Show

...en isolated from humans andis identified as having pandemic potential. "This is the first time Novavax has me...avax is developing vaccines to protectagainst H5N1 pandemic influenza, seasonal flu and other viraldiseases. Novavax's particulate vaccines closely matchdisease...

Baxter Announces Final Phase I/II Data and Initiation of Phase III Clinical Trial for Candidate Pandemic H5N1 Influenza Vaccine

...ase I/II data for itsadjuvant-free investigational pandemic H5N1 influenza vaccine andplans to initiate a Phas...date vaccine isthe first cell-based candidate H5N1 pandemic vaccine to undergoclinical evaluation. Final Phase I/II Data Presented Final data from the Phase I...