neurons

Stanford Researchers Find Brain Pathway of Depression in Rats

...real time, enabling theresearchers to watch living neurons in action, across entire brainnetworks. The syste...tart, she said, was to look at theformation of new neurons in the hippocampus, a process thatneuroscientists have suggested is at the root of howantidepressant...

Expert Opinion Highlights Avigen's AV411 as Potential New Therapeutic for Neuropathic Pain and Opioid Withdrawal

...eand withdrawal. Glia cells surround and influence neurons thatsignal pain. The Expert Opinion in Investigational Drugs article, entitled"Ibudilast (AV411): A New Class Therapeutic Candidate forNeuropathic Pain and Opioid Withdrawal Syndromes," by lead authorAnnemarie Ledeboer, Ph.D., reports that, through ...

Resveratrol Studies Suggest Broad Implications for SIRT1 Activation in Neurodegenerative Diseases of Aging Such as Alzheimer's Disease

... It is well established that a progressive loss of neurons withage underlies a variety of debilitating neurological disordersincluding Alzheimer's Disease and Amyotrophic Lateral Sclerosis(ALS), neurodegenerative diseases which have been associated withreduced mitochondrial function. Sirtuins are a recently ...

Trophos Publishes ALS Article in Journal of Pharmacology and Experimental Therapeutics

...preclinical models in vivo, TRO19622 rescues motor neurons fromaxotomy-induced cell death in neonates and pro...raging that TRO19622 promotesthe survival of motor neurons in this extensive battery ofpreclinical models. These studies, along with the excellentclinical safe...

Pluristem's PLX Cells Demonstrate Potential to Treat Parkinson's Disease

...be differentiated into dopaminergic neurons. These neurons werefound to have properties favorable to cells, w... of elevated nurr1 mRNAlevels. Additionally, these neurons were found to secrete favorableneurotrophic factors such as GDNF, BDNF, IGF-1, and astrocytesmarkers...

Ivivi's PEMF Technology Significantly Improves Neuron Survival in Parkinson's Disease Model, Study Finds

...th reduce levels ofinflammation as well as protect neurons from inflammatoryeffects." "Dr. Casper's work d...ntial to delay orprevent the death of dopaminergic neurons could provide newopportunities for Ivivi." Andre' DiMino, Co-CEO, Ivivi Technologies noted, "Thisne...

Study Suggests Strattera Improved ADHD Symptoms in Patients With Comorbid Alcohol Abuse

...smore norepinephrine at work in the spaces between neurons in thebrain. Improved efficiency in the norepinephrine system isassociated with improvement in symptoms of ADHD.(4) Important Safety Information In some children and teens, Strattera increases the risk ofsuicidal thoughts. A combined analysis of 12...

Data to be presented at AAN Meeting -Study results of drug candidate for MS

...iscaused by the destruction of myelin, which helps neurons carryelectrical signals in the brain. MS is the most common inflammatoryand neurodegenerative disorder of the CNS, causing problems withmuscle control and strength, vision, balance, sensation and mentalfunction. MS typically presents in relapsing for...

Ceregene Presents Interim Phase 1 Clinical Data of CERE-110 for the Treatment of Alzheimer's Disease

...years, showing thatimproving the function of these neurons can significantly reducethe memory loss in this disease". About CERE-110 CERE-110 is composed of an AAV vector carrying the gene for NGF,a naturally occurring protein that maintains survival of nervecells in the brain. CERE-110 is surgically implan...

Phase III Data on Safinamide in Parkinson’s Disease Presented at American Academy of Neurology 59th Annual Meeting

... of dopamine, which is produced inthe dopaminergic neurons of the brain. Secondary symptoms mayinclude high level cognitive dysfunction and subtle languageproblems. Parkinson’s disease is both chronic andprogressive. ### Forward-looking statements Some of the statements in this press release areforw...

Ceregene Presents Long Term Follow-Up Data From Phase 1 Trial of CERE-120 Demonstrating Improved Motor Function in Parkinson's Patients

...region of the brain affected by thedegeneration of neurons in Parkinson's disease. CERE-120 was delivered at...th have been shown to benefit themidbrain dopamine neurons that degenerate in Parkinson's diseaseand are responsible for the major motor impairments. CERE-120 ...

Fragile X, Down Syndromes Linked to Faulty Brain Communication, Stanford Researcher Finds

... be completely disordered, withconnections between neurons making random paths like hairlinecracks racing across a breaking sheet of ice. But as the person oranimal begins to learn and remember, the more well-trodden paths,or cracks, connect in purposeful, yet unique ways. "No two nerve cells will always be...

Emisphere Technologies, Inc. Reports Clinical Data on Oral Delivery of GLP-1 and PYY

...ry presynaptic receptor, is highly expressed onNPY neurons in the arcuate nucleus, which is accessible toperipheral hormones. Peptide YY 3-36, a Y2R agonist, is releasedfrom the gastrointestinal tract postprandially in proportion to thecalorie content of a meal. It is believed that PYY may be animportant reg...