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Nerve in Medical Technology

CeNeRx BioPharma Obtains Rights to Novel Drug Candidate for Prevention and Treatment of Neurodegeneration Disorders

... --Orally Active Enhancer of Human nerve Growth Factor Has Demonstrated Promising Activity ... orally active agent that enhances the effects of nerve growth factor (NGF). CeNeRx intends to initiate ... CXB909 is a downstream enhancer of the effects of nerve growth factor, an endogenously produced ...

Video: UCB Launches Vimpat(R) in the U.S. for Add-On Treatment of Epilepsy in Adults

... the activity of the nervous system to help nerve cells communicate. Sometimes sodium channels are abnormally overactive and nerve cells become too excited, which may produce a ... then regulates the activity of over-excited nerve cells, which may contribute to the control of ...

Metastatic Bone Disease Patients Can Walk in Lazarus' Footsteps

... and weak. As the bones are replaced with tumor, nerve endings in and around the bone send pain signals ... or cold to desensitize the bone by killing the nerve endings in the vicinity of the metastasis. Once the nerve endings are dead, interventional radiologists can ...

Got Pain?

... causing the fingers to curl toward the palm) and nerve pain, explains Dr. Osterman. But new treatments, like arthroscopy, collagenase injections, nerve wraps, desensitization techniques, therapeutic ... for patients with Dupuytren's contracture." nerve pain ( ...

Patient Enrollment in Urgent(R) PC SUmiT Clinical Trial Completed Ahead of Schedule

... compare the effectiveness of percutaneous tibial nerve stimulation (PTNS) using Urgent PC to a ... system is a proprietary, minimally invasive nerve stimulation device designed for office-based ... of neuromodulation therapy targets specific nerve tissue and disrupts the signals that lead to ...

Wrist Access Safer, Easier for Many Patients Undergoing Minimally Invasive Treatment of Blocked Heart Arteries

... keep it open. But there is a risk of bleeding and nerve damage at the femoral artery access site. To ... significantly reduces the risk of bleeding and nerve damage, suggests data on more than 5,000 ... used, there is a 2.8 percent risk of bleeding or nerve damage, according to studies. Most patients spend ...

MRI Emerges As Vital Resource in Treatment of Back Pain

... pathology including; diseases of the spinal cord, nerve roots, vertebrae, disks and blood vessels. With ... method available for patients with pacemakers, nerve stimulators, or those who suffer from ... to find out which disk is causing pain, which nerve is firing, which metabolites are present in ...

Sangamo BioSciences Provides Update on Company's 2008 Progress and 2009 Objectives

... significant improvements in measures of nerve health at 180 days post treatment. -- ... observed in improvement in measures of nerve health between placebo and treated subjects at ... with moderate to severe DN with a blocked nerve and SB-509-703 in stem cell mobilization. ...

PharmAthene Initiates Phase I Clinical Trial of Nerve Agent Bioscavenger Protexia(R)

... recombinant bioscavengers for prophylaxis against nerve agent poisoning," stated David P. Wright, ... that Protexia(R) used as a prophylactic against nerve agents might offer important benefits over medical countermeasures for nerve agent poisoning," continued Mr. Wright. ...

Protein Shown to Play a Key Role in Normal Development of Nervous System

... protein helps precise connections to form among nerve cells may provide a basis for eventual treatments ... promotes the growth of dendrites, both in nerve cell cultures and in the nervous system of mice. Dendrites are branching extensions of nerve cells that carry signals into the cell. The most ...

Quark Pharmaceuticals Announces First RNAi Drug Candidate Having a Novel, Proprietary Structure Covered by Quark Intellectual Property

... different animal models of acute and severe optic nerve injury. In collaboration with Prof. Ann Logan of ... of retinal ganglion cell (RGC) death by optic nerve crush (ONC). In a second study of QPI-1007 in ... and also in slow-progressing chronic optic nerve injuries such as glaucoma. QPI-1007 has the ...

PharmAthene Presents Data for Protexia(R) and Valortim(R) at 2008 BARDA Industry Conference / PHEMCE Stakeholders Workshop

... on the battlefield or civilian victims of nerve agent attacks. Valortim(R), in co-development ... may have efficacy as a therapeutic against nerve agent exposure. -- A study of Valortim(R) in a ... and degrade organophosphate poisons (e.g. nerve agents) before they cause neurological damage. ...

AMT Obtains License to Amgen's GDNF Gene to Develop Treatment for Parkinson's Disease with AMT's Proprietary Gene Therapy Platform

... is caused by degeneration and death of nerve cells in a specific part of the brain. These ... a substance necessary for communication between nerve cells involved in the coordination of ... by Parkinson's disease." Protect and improve nerve cells with GDNF The GDNF gene contains the ...

Sangamo BioSciences Initiates Phase 2 Clinical Trial of Treatment for Amyotrophic Lateral Sclerosis (ALS)

... cell mobilization. VEGF-A has been shown to have nerve protection properties as well as promoting nerve, ... growth. In ALS, the motor nerves comprised of nerve cells in the brain and spinal cord that control ... voluntary muscles, gradually degenerate. As the nerve cells begin to die, the muscles weaken and ....

The University of Nottingham in the British Midlands Announces Breakthrough in Parkinson's Disease Research

... model with the type of brain degeneration, or nerve cell loss, seen in Lewy body disease and ... Lewy bodies is a key event in the development of nerve cell death associated with Parkinson's disease. ... will help us to figure out what happens when nerve cells die in Parkinson's and from this to ...

Device Blocking Stomach Nerve Signals Shows Promise in Obesity

... the 31 obese participants who received the vagal nerve blocking device, also called VBLOC(TM) vagal ... initial assessment of whether blocking the vagus nerve electrically could cause obese patients to ... it uses high-frequency electricity to block the nerve impulses between the brain and the stomach and ...

Headache Specialists Convene in Boston For 50th Annual American Headache Society Meeting

... in a variety of ways, such as by a virus, nerve damage or even medication. Morphine and ... Near-Daily Migraines Stimulating a nerve might be just the ticket to help relieve the pain of chronic migraine sufferers. Occipital nerve stimulation, in which an implanted ...

Sangamo BioSciences Announces Presentation of Phase 1b ZFP Therapeutic Data at American Diabetes Association Meeting

... were observed in measurements of nerve health and function in subjects with mild to ... SB-509 is designed to address the actual nerve damage. These data demonstrate that SB-509 may ... there was a trend towards improvement in nerve conduction velocity (NCV), a measure of the ...

Sangamo BioSciences Provides Update on Diabetic Neuropathy Clinical Programs

... of the endpoint in this trial -- recovery of nerve conduction velocity or NCV -- these additional ... in diabetic subjects that have unmeasurable nerve conduction velocity (NCV) in at least one of the ... with so-called "blocked nerves" or unmeasurable nerve conduction velocity measurements in the leg ...

Uroplasty Highlights Clinical Results From a Study of the Urgent(R) PC Neuromodulation System

... Study Results Comparing Percutaneous Tibial nerve Stimulation with Pharmaceutical Therapy at the ... minimally invasive percutaneous tibial nerve stimulation (PTNS) device designed for ... Multi-center Study Comparing Percutaneous Tibial nerve Stimulation with Pharmaceutical Therapy for ...

PharmAthene's Recombinant Butyrylcholinesterase (rBChE) May Play A Neuroprotective Role in Alzheimer's Disease

... to additional areas beyond organophosphorous nerve agent toxicity with potentially important ... against acute organophosphorous (OP) nerve agent toxicity. About Chemical Weapons Organophosphorous nerve agents, or anti-cholinesterase agents, ...

Study Finds Starion Instruments' Tissue Welding Technology Safe and Effective in Parotidectomy Procedures

... particular interest was the incidence of facial nerve palsy since this is one of the most severe ... postoperative complications of bleeding, facial nerve paresis, salivary fistula, and gustatory ... this instrument can be used close to the facial nerve and that no current passes through the patient, ...

Sangamo BioSciences Announces Completion of Enrollment of Phase 2 Clinical Trial of ZFP Therapeutic for Diabetic Neuropathy

... improvements in motor and sensory nerve conduction velocities (NCV) and a trend towards ... of vibration, electrophysiological testing using nerve conduction velocity (NCV) to assess the rate at ... the direct therapeutic effect of SB-509 on nerve regrowth. This test may provide an ...

Diamyd Updates Gene Therapy Program and Outlines Plans for Phase I Clinical Trial for Treatment of Cancer Pain

... NP2, the company's first drug candidate in its nerve targeting drug delivery system (NTDDS) gene ... license rights to a portfolio of patents for the nerve Targeting Drug Delivery System (NTDDS). This ... genes. The NTDDS has a natural affinity for nerve cells. Diamyd's initial NTDDS projects are ...

Dirucotide Does Not Meet Primary Endpoint in Phase III MAESTRO-01 Trial in Secondary Progressive Multiple Sclerosis

... MS is caused by damage to myelin, the protective sheath surrounding nerve fibers in the central nervous system, resulting in disrupted nerve impulses traveling to and from the brain and spinal cord(iii). Symptoms ...

July 2009 Mayo Clinic Health Letter Highlights a Positive Outlook, Bell's Palsy and Heart Valve Repair

... The disorder is often related to a viral infection. The nerve that controls facial muscles passes through a narrow corridor of bone on its way to the face. If the nerve becomes inflamed or swollen, typically due to a viral infection, it can ...

UNT Health Science Center's Groundbreaking Research Applied to Protecting Brain After Traumatic Injury

... In 1994, Simpkins discovered that estrogens were protective to nerve cells and subsequently has demonstrated that, if administered soon after brain injury in animals, estrogens can protect nerve cells and reduce neurological deficits. Application of these discoveries ...

Data Demonstrates Long-Term Reduction In Seizure Frequency With Novel Once Daily Anti-Epileptic Zebinix(R)

... Epilepsy is characterised by abnormal firing of impulses from nerve cells in the brain. In partial-onset seizures, these bursts of electrical ... Nerve impulses are triggered via voltage-gated sodium channels in the nerve cell membrane. Treatment of partial-onset seizures, the most common ...

Autism Genes Discovered; Help Shape Connections Among Brain Cells

... Neuronal cell-adhesion molecules are important because they affect how nerve cells communicate with each other, thought to be an underlying problem in ... Ubiquitins are a class of enzymes that eliminate connections among nerve cells, and are involved with processing and degrading neuronal ...

Study Shows Leconotide, an Investigative Calcium Channel Blocker, Has Potential as a Selective, Efficacious, Non-Opioid Pain Treatment

... or rate of electrical firing or production of chemical messengers in nerve cells. Calcium antagonists block calcium channels. There are many types ... heart and blood vessels to lower blood pressure). Calcium channels in nerve cells are involved with many functions (e.g., pain, memory and control of ...

Roskamp Institute Identifies New Class of Drugs to Treat Alzheimer's Disease

... response. This inflammatory response is thought to be detrimental to nerve cells, eventually causing their destruction. Recent research at ... more amyloid, and researchers have found that a specific receptor on the nerve cell surface, known as CXCR2, is an interface between inflammation and new ...

Aiming at Multiple Alzheimer's Proteins May be Key to Success

... an accumulation of beta amyloid protein "plaques" around the brain's nerve cells and tau protein "tangles" within these cells is connected to a ... of both beta amyloid and tau, before they begin to affect the brain's nerve cells. "Alzheimer's disease is a complex ailment and may have overlapping ...

Uroplasty Enrolls First Patients in Urgent(R) PC Clinical Trial

... is a minimally invasive, office-based, nonsurgical, percutaneous tibial nerve stimulation (PTNS) device that treats these symptoms. The Company believes ... PC system, which we believe is the only FDA-approved minimally invasive nerve stimulation device designed for office-based treatment of urinary urgency, ...

FDA Lifts Clinical Hold on Genta's Tesetaxel, a Leading Oral Taxane

... myelosuppression (low blood counts) and peripheral neuropathy (disabling nerve damage). With administration as an oral capsule, tesetaxel was developed ... unlike other oral taxanes that are currently in clinical development, nerve damage has not been a prominent side effect of tesetaxel. Thus, the drug ...

Alseres Pharmaceuticals, Inc. to Address a Congressional Briefing on Paralysis Research and the Spinal Cord Injury Community at 'Working 2 Walk' in Washington, DC, April 13-15, 2008

... CETHRIN with the aim of providing a first-ever therapeutic option for nerve repair to patients with acute spinal cord injury, we are committed to the ... initiatives. CETHRIN, a recombinant-protein-based drug designed to promote nerve repair after acute spinal cord injury, demonstrated positive interim ...

NeurogesX Announces Preliminary Results from Second Phase 3 Clinical Trial in HIV-DSP

... About PHN and HIV-DSP PHN is a painful condition affecting sensory nerve fibers. It is a complication of shingles, a second outbreak of the ... Following an initial infection, some of the virus can remain dormant in nerve cells. Years later, age, illness, stress, medications or other factors ...

Sangamo BioSciences Reports 2007 Fourth Quarter and Year-End Financial Results

... sensory testing and clinically relevant trends toward improvement in nerve conduction velocity in subjects with mild to moderate diabetic ... on stem cell mobilization, ALS, cancer, HIV/AIDS, neuropathic pain, nerve regeneration, Parkinson's disease and monogenic diseases. Sangamo's core ...

Ceregene Presents Long-term Follow-up From Phase 1 Trial of CERE-120 in Parkinson's Disease

... in the United States. It is caused by a reduction in dopamine containing nerve cells of the midbrain. Dopamine is a neurotransmitter involved in ... clinical programs include CERE-110, an AAV2 based vector expressing nerve growth factor that is currently in Phase 1/2 studies for the treatment ...

Anesiva Defines Regulatory Pathway for Adlea with FDA

... and end-stage osteoarthritis. Because it selectively acts on pain-sensing nerve endings, Adlea does not affect other nerve fibers necessary for sensory or motor sensations and proprioception. ...

Anesiva Initiates Phase 2 Trial with Adlea(TM) for Pain Relief Following Total Hip Replacement Surgery

... and end-stage osteoarthritis. Because it selectively acts on pain-sensing nerve endings, Adlea does not affect other nerve fibers necessary for sensory or motor sensations and proprioception. ...
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(Date:12/4/2009)... (EEG) is widely used by physicians and scientists...cal disorders. However, it has remained largely un...xact view of what is happening inside the brain. S...al Cybernetics in Tbingen, Germany, have now found...hin the brain to that measured with EEG. These fin...
(Date:12/4/2009)...hallenging accepted thinking about amyloids the f...uch as Alzheimer,s and Parkinson,s and may open u...s believed that amyloid fibrils - rope-like struct... - are inert, but that there may be toxic phases d...ause disease. , But in a paper published today ...
(Date:12/3/2009)...ew information and adapt to changes in our daily e..., appears to lie in the minute junctions where ner...NYU Langone Medicine Center researchers. The study...ure . , The scientists, led by Wen-Biao Gan, Ph...nce at NYU School of Medicine, discovered that a d...
Breaking Biology News(10 mins):How to read brain activity? 2New therapy targets for amyloid disease 2Lifelong memories linked to stable nerve connections 2UnisourceDirect 26amp 3B 238482 3B Web Site Now Offering Products to Maintain a Healthy School Environment 56865 1UnisourceDirect 26amp 3B 238482 3B Web Site Now Offering Products to Maintain a Healthy School Environment 56865 2UnisourceDirect 26amp 3B 238482 3B Web Site Now Offering Products to Maintain a Healthy School Environment 56865 3GENova to acquire three new drug target patents worth in excess of 241 billion in royalty fees 56862 1GENova to acquire three new drug target patents worth in excess of 241 billion in royalty fees 56862 2GENova to acquire three new drug target patents worth in excess of 241 billion in royalty fees 56862 3President Obama Misleads Public on Health Care for Illegal Aliens 3B Illegal Aliens Would Benefit Under H R 3200 56859 1President Obama Misleads Public on Health Care for Illegal Aliens 3B Illegal Aliens Would Benefit Under H R 3200 56859 2
(Date:12/4/2009)...s Claim That Health Reform Bills Will Increase Def...re/ -- Despite claims that the pending health refo...ever lets Medicare savings take effect, Congress h... it enacted in the past two decades to take effect... the Center on Budget and Policy Priorities shows....
(Date:12/4/2009)...atic weight loss can be an effective way to improv...he Swedish medical university Karolinska Institute...study began benefited most from weight loss. , ...ffective treatment strategy for sleep apnoea in ob...ers involved in the study. , Sleep apnoea the t...
(Date:12/4/2009)... Pure Power Mouthguard (PPM) - certified Dr. Nas...e dental treatment and options , ...- Miami dentist Dr. H.A. Nassery contributes to ...ental problems in young athletes and offering the ... diagnosed and treated Ashley Kimmel, a student at...
(Date:12/4/2009)...ot clear enough to recommend its use, experts say ...- Cancer patients, glaucoma patients and others ca...alysis shows that it can help multiple sclerosis (...at are the hallmark of the debilitating autoimmune...binoids in MS appears to be comprehensive, and sho...
(Date:12/4/2009)...TON and HOUSTON, Dec. 4 .... (Nasdaq: CYBX ) announced today that Vagus Ner...ed implantable medical device for the treatment of...ntations at the American Epilepsy Society,s (AES)... Hynes Convention Center in Boston, Massachusetts....
Breaking Medicine News(10 mins):Health News:Congress Has Allowed Most Previous Medicare Cuts to Take Effect, New Study Shows 2Health News:Congress Has Allowed Most Previous Medicare Cuts to Take Effect, New Study Shows 3Health News:Congress Has Allowed Most Previous Medicare Cuts to Take Effect, New Study Shows 4Health News:Weight-loss proves effective cure for sleep apnea 2Health News:Weight-loss proves effective cure for sleep apnea 3Health News:Miami Dentist Dr. H.A. Nassery Treats Local Teen Golf Star and Helps Improve Her Performance 2Health News:Review Finds Marijuana May Help MS Patients 2Health News:Review Finds Marijuana May Help MS Patients 3Health News:NYU Langone Medical Center Study Shows VNS Therapy is a Safe and Effective Treatment for Refractory Epilepsy 2Health News:NYU Langone Medical Center Study Shows VNS Therapy is a Safe and Effective Treatment for Refractory Epilepsy 3
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