Point of Care Strep Tests Speed Treatment, Lower Costs
...a reassay in those instances when RADT results are negative yet clinical findings support a diagnosis of Strep...ored at room temperature and includes positive and negative external controls. The OSOM Ultra Strep A Test from Genzyme, Cambridge, Mass., is a color immun...Rapid Whole Blood Testing for Infectious Mononucleosis Antibodies
...indicate a positive result; a red line indicates a negative test outcome. The product provides two visible ind...le the absence of a visible color band indicates a negative result. Regardless of test outcome, the control band includes a procedural indicator to assure the p...Fast, Accurate Influenza A/B Antigen Detection
...rapid tests, physicians should consider confirming negative tests with viral culture or other means....Monitoring Options Expand for Therapeutic Agents and Drugs of Abuse
...colorimetric reading indicating either positive or negative test results. Craig Medical Distribution, Inc., V...ests with at least one study suggesting that false negative tests can be as high as 6-40 percent in a certified laboratory, depending on the drug detected. All...Point of Care Cardiac Analyzers Yield Rapid Cardiac Marker Results
...enting with acute coronary syndrome (ACS) who have negative 12-lead EKGs. About 30% of patients previously considered to have unstable angina are now given a diagnosis of myocardial infarction without ST-segment elevation based on their cardiac troponin levels. Troponin levels additionally aid in risk strat...New Assays to Detect Disseminated Fungal Infections
...tection of Candida , Fungitell has demonstrated a negative predictive value of 100% and a favorable positive ...ccuracy, with positive predictive value of 70% and negative predictive value of 96%. Syscan3, made by Rockeby Biomed, is another ELISA test for host antibodies ...Testing for Human Papillomavirus
... and though less specific, HPV-positive women with negative or borderline cytology can be monitored by repeat testing, thereby reducing total colposcopy referrals while maintaining improved detection of precancerous lesions. Because of the low cancer risk and unknown natural history of HPV infection in men, ...Appendicitis: Evolving Tools to Diagnose a Classic Disease
...when appendicitis is suspected, a normal CRP has a negative predictive value near 100%. Antibody-based assays are available to determine CRP levels in well under an hour. Computed tomography (CT) of the abdomen is a mainstay and is particularly helpful if the appendix is visible on the scan. With oral or re...Avian (Bird) Flu: Is There a Role for Rapid Tests?
...her subtypes. An equally important question is the negative predictive value of rapid tests. The WHO points out that a negative result on a rapid test does not rule out avian flu infection. Obviously, failure to detect even one......a'sIncreased CV Risk, suggests, however, a greater negative responseby internists than endocrinologists. The GfK Market Measures study showed universal awareness of theNEJM report, though not all physicians recalled the exactpercentages. The internists, however, demonstrated the strongestnegative impact to th...Insmed Inc. to Present at C.E. Unterberg, Towbin Growth Conference
...ase, the biopharmaceutical industry may experience negative market trendsand other risks and challenges detailed in the Company'sfilings with the U.S. Securities and Exchange Commission,including the Company's Quarterly Report on Form 10-Q for thequarter ended March 31, 2007. Readers are cautioned not top...... response includes bothimmunofixation positive and negative readouts Contacts: Jennifer Snyder (media) Kyle Kuvalanka (investors) (617) 444-1439 (857) 498-0818 CONTACT: Media, Jennifer Snyder, +1-617-444-1439; Investors,KyleKuvalanka, +1-857-498-0818, both of Millennium ...Major New Review Supports the Broader Potential of CeNeS COMT Inhibitor Discovery Programme
...herapeutic utilityin addressing the poorly treated negative symptoms ofschizophrenia. This is in addition to t... hallucinations anddelusions as well as a range of negative symptoms, includingcognitive disturbances. Cognitive disturbances often preventschizophrenia patient......response includes bothimmunofixation positive and negative readouts Editors' Note: This press release is also available under theMedia section of the Company's website at: <a target="_blank" href="http://www.millennium.com/">www.millennium.com . Contacts: Jennifer Snyder (media) Kyle Kuvalanka (in......response includes bothimmunofixation positive and negative readouts Editors' Note: This press release is also available under theMedia section of the Company's website at: <a target="_blank" href="http://www.millennium.com/">www.millennium.com . Contacts: Jennifer Snyder(media) ......appearance of M-protein (a marker of tumorburden); negative immunofixation testing; no increase in size ornumber of lytic bone lesions; and disappearance of soft tissuetumors (plasmacytomas). "Partial" remissions and "minimal"responses represented lesser degrees of response based on the samecriteria. Worsenin...Gentium's Defibrotide Seen as Active in Multiple Myeloma
...stimate," "predict," "potential" or"continue," the negative of these terms and other comparableterminology. These statements are not historical facts but insteadrepresent the Company's belief regarding future results, many ofwhich, by their nature, are inherently uncertain and outside theCompany's control. It......at adversely affect fertility can alsocompound the negative impact of the disease on a patient's qualityof lif...tus. Women of childbearing potential should have a negative serumor urine pregnancy test with a sensitivity of at least 50 mIU/mLwithin one week prior to beginn......onstant tingles.Neuropathic pain has a significant negative impact on quality oflife. The precise causes of neuropathic pain are unknown, butconditions associated with the development of neuropathic paininclude diabetes mellitus, chemotherapy, shingles, HIV infection,and trauma. Patients are often prescribed......continues," "forecast," "designed," "goal," or the negative ofthose words or other comparable words to be uncertain andforward-looking. These factors and others are more fully discussedin Micromet's periodic reports and other filings with the SEC,including the "Risk Factors" sections of such reports. Any for...Insmed Inc. Welcomes Studies Linking IGFBP-3 to Prevention of Blindness in Premature Infants
...ease,the biopharmaceutical industry may experience negative markettrends and other risks and challenges detailed in the Company'sfilings with the U.S. Securities and Exchange Commission, includingthe Company's Quarterly Report on Form 10-Q for the quarter endedMarch 31, 2007. Readers are cautioned not to plac...HepaLife's PBS-1 Cells for Influenza Vaccine Production Prove Superior at International Conference
...estimate,""believe," "intend," or "project" or the negative of these words orother variations on these words or comparable terminology. Thereader is cautioned not to put undue reliance on theseforward-looking statements, as these statements are subject tonumerous factors and uncertainties, including but not l...... through March 31, 2007, itincurred net losses and negative cash flows from operatingactivities of approximately $22.7 million and $17.4 million,respectively. Management believes that the Company will continue toincur net losses and cash flow deficiencies from operatingactivities for the foreseeable future. B......t affect thetherapeutic activity of FSH or cause a negative immune systemresponse in patients. Modigene has an exclusive license withWashington University for use of the CTP with all proteins exceptfour endocrine proteins, which are licensed toSchering-Plough/Organon. ABOUT MODIGENE Modigene Inc. is a publi......," "continue," and other similar terminologyor the negative of these terms, but their absence does not meanthat a particular statement is not forward-looking. Suchforward-looking statements are not guarantees of future performanceand are subject to risks and uncertainties that may cause actualresults to diffe......acy has notbeen demonstrated in oestrogen receptor negative patients unlessthey had a previous positive clinic...endemonstrated in patients with oestrogen receptor negative status.Previously, the IES study has demonstrated an overall survivalbenefit for exemestane in only ......acy has not been demonstrated inoestrogen receptor negative patients unless they had a previouspositive clinic...endemonstrated in patients with oestrogen receptor negative status.Previously, the IES study has demonstrated an overall survivalbenefit for exemestane in only ...... anti-human antibodies (HAHAs). All patientstested negative at 24 weeks. Overall, 72% (300 mg p<0.001; 700 mg p=0.001; 1000 mgp=0.001) of patients treated with each of the ofatumumab dosesexperienced at least a moderate (moderate or good) EULAR responsecompared to 40% of patients receiving placebo at wee......, which normallydeclines with age, leading to many negative conditions commonlyassociated with aging. Noel Thomas Patton, Founder and Chairman of TA Sciences said:"Taken together, the results of the Pivotal 2005 Anti-Aging Trialof TA-65 provide the first proof ever recorded of the vast,powerful, and tangib......d both primary and secondary endpoints ofstudy; no negative drug-drug interaction was observed betweenvalopicitabine and ribavirin ~ CAMBRIDGE, Mass., June 12, 2007 /PRNewswire-FirstCall/ -- IdenixPharmaceuticals, Inc. today announced results from a phase II studydesigned to evaluate triple combination therap...IDM Pharma Presents Preliminary Results from Phase II UVIDEM Melanoma Vaccine Clinical Trial
...by the decision of any advisorypanel, the possible negative impact that the opinion of the FDA'sOncologic Drug Advisory Committee that the results of the Company'sPhase III trial do not provide substantial evidence ofeffectiveness of JUNOVAN in the treatment of patients withnon-metastatic, resectable osteosar......ver AC-T in node positive and high risk node negative HER2 positive early breast cancer patients: Quality of Life (QOL) at 36 months follow-up -- Dr. Alexander Spira: Perifosine (P) an active agent in the treatment of patients with advanced sarcoma -- Dr. Alexander Spira: iTARGET: A ......2 patients were evaluated. Sixteen werefound to be negative for cancer (the adjuvant group) after surgerywhile the other 16 patients were found to have evidence ofrecurrent disease (the non-adjuvant group). Six weeks after liver surgery, both groups of patients receivedan initial dose of 40 - 50 mCi/m2 of ......, "will," "may", "should", "approximately",and the negative or other variations of those terms or comparableterminology, are forward-looking statements. Such statementsreflect management's current views, intentions, strategies andplans and are based on certain assumptions. Forward-looking statements involve ...IDM Pharma Announces UVIDEM(R) and EP-2101 Data Presentations at 2007 ASCO Annual Meeting
...by the decision of anyadvisory panel, the possible negative impact that the opinion ofthe FDA's Oncologic Drug Advisory Committee that the results of theCompany's Phase III trial do not provide substantial evidence ofeffectiveness of JUNOVAN in the treatment of patients withnon-metastatic, resectable osteosar...HepaLife Announces Scientific Presentation of PBS-1 Cell Line at International Influenza Meeting
...estimate,""believe," "intend," or "project" or the negative of these words orother variations on these words or comparable terminology. Thereader is cautioned not to put undue reliance on theseforward-looking statements, as these statements are subject tonumerous factors and uncertainties, including, but not ...New Pfizer Oncology Data Across Numerous Cancer Types to be Presented at ASCO
...ious types ofadvanced breast cancer including HER2 negative and positive, andpreviously treated advanced triple receptor negative (ER-, PR- andHER2-). The phase II and III randomized, open-label studies that arecurrently enrollin...Limiting Eligibility for Medical Studies Can Omit Women, African-Americans, Stanford Study Finds
...ict study eligibility criteria can haveunintended, negative consequences. In reviewing data from a pool of 100,000 alcohol treatmentpatients, Keith Humphreys, PhD, professor of psychiatry andbehavioral sciences, determined that women and African-Americanswere substantially more likely to be excluded from trea...Investigational Study Evaluates the Effectiveness of Aripiprazole in Adolescents With Schizophrenia
...Secondaryendpoints included the PANSS positive and negative subscales andthe Clinical Global Impression of Improvement (CGI-I) scale.Important safety measures included incidence of adverse events,discontinuation from study due to adverse events, and laboratorymeasures. Approximately 85 percent of 302 randomi......ore than 30 days in the past year,underscoring the negative impact of UC on patients' ability tofunction in the workplace. "Many patients with ulcerative colitis report experiencingextremely bothersome symptoms, that affect many areas of theirlives, including their ability to maintain full-time employment an......, "will," "may", "should", "approximately",and the negative or other variations of those terms or comparableterminology, are forward-looking statements. Such statementsreflect management's current views, intentions, strategies andplans and are based on certain assumptions. Forward-looking statements involve ...Antipsychotic Iloperidone Results Show Favorable Akathisia Profile
...ntagonism may provideefficacy against positive and negative symptoms of schizophrenia,while causing reduced EPS and hyperprolactinemia relative to otheravailable atypical antipsychotics. Iloperidone also appears to havea favorable weight and metabolic profile. In addition, Vanda isdeveloping a genetic blood t......y scale from 1-7. PANSS positive (7 items), negative (7 items), and general psychopathology (16 ...f symptoms in schizophrenia,including positive and negative symptoms as well as symptoms ofgeneral psychopathology, aggression, and depression. Efficacy wasasse...... UnitedStates. It is characterized by positive and negative symptoms suchas hallucinations, delusions, poverty of speech, disorganizedthought and emotional blunting. Severity of the symptoms and thechronic pattern of schizophrenia often cause a high degree ofdisability for patients and place a burden on famil...... dollars.Hospitalization is also associated with a negative impact onhealth-related quality of life in patients with Crohn'sdisease. Data from the Phase III, pivotal study, called CHARM, wereevaluated to assess the effect of ongoing treatment with HUMIRA onthe risk of hospitalization. At one year, this analy...Allos Therapeutics' PDX Granted Orphan Medicinal Product Designation by the European Commission
...,""continue," and other similar terminology or the negative of theseterms, but their absence does not mean that a particular statementis not forward-looking. Such forward-looking statements are notguarantees of future performance and are subject to risks anduncertainties that may cause actual results to diffe...Data Suggest Cymbalta Improved Functioning in Patients with Generalized Anxiety Disorder
..., it can bedifficult to diagnose(1) and may have a negative impact on aperson's ability to function properly in work, family and socialsituations.(2) "This study underscores the importance of treating all of themany symptoms of GAD and reducing the global functional impairmentassociated with the disorder," s...... with chronichepatitis B (HBeAg positive and HBeAg negative chronic hepatitis Bwho have compensated liver disease and evidence of viralreplication and liver inflammation). PEGASYS is dosed at 180mcg as a subcutaneous injection takenonce a week. COPEGUS is available as a 200mg tablet, and isadministered orall......iral load (>800,000 IU/ml), a well-established negative predictive factor forSVR. Patients received daily injections of omega interferon (25mcg) for up to 48 weeks. The endpoints for this clinical trial wereearly viral response (EVR), defined as a 2-log reduction in HCV RNAafter 12 weeks of treatment, and......eatingpatients infected by hospital-acquired, gram negative pneumonia,many of whom were infected by resistant gram negative pathogens,"said Michael S. Niederman, M.D., chairman of the Department ofMedicine at the Winthrop-Un...Data Suggest that Pegasys May be an Option in Hepatitis C Patients Unable to Tolerate Peg-Intron
... with chronichepatitis B (HBeAg positive and HBeAg negative chronic hepatitis Bwho have compensated liver disease and evidence of viralreplication and liver inflammation). PEGASYS is dosed at 180mcg as a subcutaneous injection takenonce a week. COPEGUS is available as a 200mg tablet, and isadministered orall......therapy shouldnot be initiated until a report of a negative pregnancy test hasbeen obtained immediately prior to initiation of therapy. Women ofchildbearing potential and men must use effective contraception (atleast two reliable forms) during treatment and during the 6- monthpost-treatment follow-up period. ...... Overall, 73% of subjects were naive (i.e., PCR negative andseronegative for all 4 vaccine HPV types) to al...aining 3 types. In subjects who were naive (PCR negative and seronegative) to all4 vaccine HPV types, CIN, genital warts, VIN, and VaIN caused by anyof the 4...Accelreon Pharma's ACE-031Shown to Increase Muscle Mass in Preclinical Studies
...rine models of musculardystrophy. ACE-031 inhibits negative regulators of muscle toincrease muscle mass and st...ction. ActRIIBbinds to myostatin (GDF-8) and other negative regulators of musclemass and strength. Over-expression of myostatin has been shown tocause a loss in...New Survey Finds Troubling Data on American Asthma Sufferers
...e more severe andfrequent symptoms and a generally negative attitude toward theirasthma condition than other asthma sufferers; however, they arealso more avid seekers of information to help them better managetheir asthma. -- Overdosing. While eight-in-ten (81 percent) asthma sufferers take the indi...Acceleron Pharma's ACE-031 Increases Muscle Mass and Strength in Preclinical Studies
...rine models ofmuscular dystrophy. ACE-031 inhibits negative regulators of muscleto increase muscle mass and st...ction. ActRIIB binds to myostatin(GDF-8) and other negative regulators of muscle mass and strength.Over-expression of myostatin has been shown to cause a loss i...New England Journal of Medicine Publishes New Data on Gardasil, Merck's Cervical Cancer Vaccine
... Overall, 73% of subjects were naive (i.e., PCR negative andseronegative for all 4 vaccine HPV types) to al...aining 3 types. In subjects who were naive (PCR negative and seronegative) to all4 vaccine HPV types, CIN, genital warts, VIN, and VaIN caused by anyof the 4...Gardasil Demonstrates Up to 100% Efficacy
...Gardasil® compared toplacebo in women who were negative to the relevant HumanPapillomavirus types (6, 11, 16 and/or 18) when they started thestudy, remained free of infection with the relevant HumanPapillomavirus types through month 7, received all three doses ofGardasil® within one year and had no pr......ith hotflashes and night sweats and did not have a negative effect onsexual function. The data were presented at the 55th Annual Meeting of the ofObstetricians and Gynecologists (ACOG) in San Diego. Pristiq iscurrently under review by the U.S. Food and Drug Administration(FDA) and could be the first non-horm...Early Results of the CellCept Spare the Nephron Study Examine Kidney Function
...etus. Women of childbearingpotential should have a negative serum or urine pregnancy test witha sensitivity of at least 50 mIU/mL within one week prior tobeginning therapy even where there has been a history ofinfertility, unless due to hysterectomy. Women of childbearing potential must use effective contrac...