University of Michigan Study Shows SEQUENOM's MassARRAY Technology Identifies HPV Infections Missed by Standard Hybridization Test
... 15% of women in the study group determined to be
negative for the presence of human papillomavirus (HPV) in ... HPV in nearly half (46.7%) of women who tested
negative by the Hybrid Capture 2 (HC2) test, which is ... of the 75 cervical scraping samples that were
negative for high-risk HPV by the HC2 test were positive ...
Study Demonstrating Lurasidone Is Effective in Patients With Schizophrenia Published in The Journal of Clinical Psychiatry
... measures, including the PANSS (Positive and
negative Syndrome Scale) total score (-14.1 vs. -5.5; ... positive subscale (-4.3 vs. -1.7; p=0.006), PANSS
negative subscale (-2.9 vs. -1.3; p=0.025) and CGI-S ... The condition is characterized by positive and
negative symptoms, such as hallucinations, delusions, ...
CuraGen Updates CR011-vcMMAE Data at ASCO
... for metastatic disease was 4 (range 2-11). Triple
negative disease (ER/PR/Her-2 negative) was present in 44% ... (1 confirmed), including a patient with triple
negative disease. Fifty percent (50%) of patients showed ... or similar terms, variations of such terms or the
negative of those terms. Such forward-looking statements ...
Scientists at The Karmanos Cancer Institute in Detroit Identify Potential New Target for Breast Cancer Therapy
... target for aggressive hormone receptor
negative breast cancer tumors.
(Logo: ... scientists tested 84 cases of hormone receptor
negative human breast carcinomas and discovered that the ... in 74 percent of those cases. Hormone receptor
negative breast carcinoma is considered an aggressive ...
Video: Partnership Unites UCB with Consumer Product Innovator OXO(R)
... and antibody testing for histoplasmosis may be
negative in some patients with active infection. Empiric ... of tuberculosis in patients who tested
negative for latent tuberculosis infection prior to ... of tuberculosis in patients who tested
negative for latent tuberculosis infection prior to ...
First Candidate from Esperance's Targeted Anti-cancer Platform, EP-100, Establishes Preclinical Proof of Concept
... resistant ovarian cancer cells (OVCAR-3). As a
negative control, the study utilized LHRH receptor
negative SKOV-3 ovarian cancer cells. In in vitro ... and was slow-acting (p<0.005). LHRH receptor
negative SKOV-3 cells were significantly less sensitive to ...
FDA Approves an Expanded Indication for Peginterferon-Based Combination Therapy for Patients With Chronic Hepatitis C
... and prior relapsers (patients who were HCV-RNA
negative at the end of treatment and subsequently relapsed ... In the study, patients who were HCV-RNA
negative at week 12 were treated for a total of 48 weeks ... therapy should not be started until a report of a
negative pregnancy test has been obtained immediately ...
Novexel's NXL104/ceftazidime Combination Commences Phase II Clinical Trial in Hospital Patients With Complicated Urinary Tract Infections
... treat hospital infections that are
caused by Gram
negative bacteria, including those resistant to ... of hospital infections caused by
resistant Gram
negative bacteria. The start of our first Phase II ... will be targeting infections caused by Gram
negative bacteria,
including Enterobacteriaceae and ...
Most Cancer Treatment Studies Aren't Published, Study Finds
... trials. The researchers suspect that the rate of
negative results
is much higher in the studies that have ... Sponsors may not encourage
researchers to publish
negative results. For their part, medical journal
editors may be less enthusiastic about
negative studies.
However, publication ...
MacroChem Announces Phase 2 Data for EcoNail(R) in the Treatment of Onychomycosis
... as
negative mycology (negative fungal culture and
negative KOH) and clear nail
(as determined by expert ... 100% of patients had cultures that were
negative for dermatophyte
growth. Eight of the 37 patients ... of
negative mycology (negative fugal culture plus
negative KOH evaluation) at
48 weeks. The panel observed ...
Data Presented at the American Psychiatric Association (APA) Annual Meeting Demonstrate Iloperidone's Efficacy and Safety, With Low Rates of Movement and Metabolic Adverse Events
... (p=0.000093) -- The highest sensitivity and
negative predictive value were seen with rs9643483 ... 2005 Sep 22;353(12):1209-23.
(1) Positive and
negative Symptom Scale Total (PANSS-T) (2) PANSS
negative (PANSS-N), PANSS Positive (PANSS-P) (3) Brief ...
SEROQUEL XR(TM) Receives Approval From FDA for Maintenance Treatment of Schizophrenia
... is measured on 30-item Positive and
negative Syndrome Scale (PANSS) scale. Each symptom was ... scale from 1-7. PANSS positive (7 items),
negative (7 items), and general psychopathology (16 ... Kay SR, Fiszbein A, Opler LA. The positive and
negative syndrome scale (PANSS) for schizophrenia. ...
BiPar Begins Phase 2 Study of Lead PARP Inhibitor in Triple-Negative Breast Cancer Based on Overexpression Biomarker Data
... that are estrogen-negative and
progesterone-
negative were more likely to overexpress PARP, as ... even more likely to be overexpressed in
triple-
negative tumors. That suggests that PARP inhibition may be ... and progesterone-negative and
90 percent of HER2-
negative patients. PARP is a well-characterized and ...
INVEGA(TM) Significantly Reduced Symptoms of Schizophrenia Compared to SEROQUEL(R) in Acutely Ill, Hospitalized Patients
... the PANSS, which includes positive symptoms,
negative symptoms,
disorganized thoughts and uncontrolled ... (hallucinations and delusions) and
negative symptoms (depression,
blunted emotions, and ... National Prescription Audit). (b) Positive and
negative Syndrome Scale for Schizophrenia (PANSS) is ...
AspenBio Pharma Reports Strong Results with Appendicitis Triage Blood Test from Large Multiple Hospital Study
... risk of sending
patients home because of a false
negative diagnosis. The bottom line is we
believe we can ... 99.9). Practically,
this means a patient with a
negative AppyScore has an extremely low
likelihood of ... for life threatening mis-diagnoses. The false
negative diagnosis
of appendicitis could become much less ...
Genetic Differences Predict Anti-Inflammatory Benefits From Nutritional Products
... after botanical
treatment than those who tested
negative for the IL-1 gene variations. The
genetic test ... No CRP
effect was observed in the IL-1 genotype
negative subjects. "We have known for many years that ... genetic groups based on being either
positive or
negative for the IL-1 gene variations that are associated ...
Schering-Plough Announces U.S. Filing of Mometasone Furoate/Formoterol Fumarate Combination for the Maintenance Treatment of Asthma
... for ASMANEX TWISTHALER.
You are encouraged to report
negative side effects of prescription drugs to the FDA. Visit ... FORADIL AEROLIZER is initiated.
You are encouraged to report
negative side effects of prescription drugs to the FDA. Visit ...
UPDATE: US Oncology Research Network Participates in Phase III Follow-up Study to BiPar's Investigational Cancer Drug BSI-201
... of BSI-201 which is a very promising new treatment for metastatic triple
negative breast cancer," says Dr. O'Shaughnessy. "We expect that accrual will be ... with gemcitabine and carboplatin.
Phase II of the study in triple
negative breast cancer patients found that BSI-201 + G/C resulted in a ...
SIMPONI(TM) (golimumab) Receives Positive Opinion From CHMP for Once-Monthly Subcutaneous Treatment of Rheumatoid Arthritis, Psoriatic Arthritis and Ankylosing Spondylitis
... or highly significant risk factors for tuberculosis infection and have a
negative test for latent tuberculosis. Patients receiving SIMPONI should be ... tuberculosis during and after treatment, including patients who tested
negative for latent tuberculosis infections.
The use of TNF blocking agents ...
Dainippon Sumitomo Pharma Announces Lurasidone Phase III Data in Patients With Schizophrenia
... was associated with greater improvement on both the Positive and
negative Syndrome Scale (PANSS) total score (primary endpoint) and the Clinical ... and genetic factors. The condition is characterized by positive and
negative symptoms, such as hallucinations, delusions, disorganized thinking, lack ...
Schering-Plough Highlights Hepatitis C Clinical Data Presentations at the European Association for the Study of the Liver (EASL) Annual Meeting
... high baseline viral load (greater than or equal to 600,000 IU/mL), both
negative factors for achieving SVR.
Eligible patients were randomized to one ...
Pregnancy
REBETOL therapy should not be started until a report of a
negative pregnancy test has been obtained immediately prior to planned initiation ...
Ground-Breaking Combination of All-Oral Agents Demonstrates Potential as Hepatitis C Treatment Regimen
... of adult patients with chronic hepatitis B (HBeAg positive and HBeAg
negative chronic hepatitis B who have compensated liver disease and evidence of ... anemia).
COPEGUS THERAPY SHOULD NOT BE STARTED UNLESS A REPORT OF A
negative PREGNANCY TEST HAS BEEN OBTAINED IMMEDIATELY PRIOR TO INITIATION OF ...
Roche and Pharmasset Initiate Phase IIb Clinical Trial of R7128, Most Advanced Nucleoside Polymerase Inhibitor in Development for Chronic Hepatitis C
... of adult patients with chronic hepatitis B (HBeAg positive and HBeAg
negative chronic hepatitis B who have compensated liver disease and evidence of ... anemia).
COPEGUS THERAPY SHOULD NOT BE STARTED UNLESS A REPORT OF A
negative PREGNANCY TEST HAS BEEN OBTAINED IMMEDIATELY PRIOR TO INITIATION OF ...
Novexel's NXL104/ceftazidime Combination Commences Second Phase II Clinical Trial in Hospital Patients With Complicated Intra-Abdominal Infections (cIAIs)
... is being developed to treat hospital infections that
are caused by Gram
negative bacteria, including those resistant to many
currently used antibiotics. ... combination with the cephalosporin antibiotic
ceftazidime for serious Gram
negative infections, and the oral streptogramin
antibiotic, NXL103, for the ...
Medarex Announces Initiation of Phase 1b Clinical Development Program with MDX-1106 for the Treatment of Cancer
... binding of PD-1 with one of two ligands (PD-L1 or PD-L2) is an important
negative regulation pathway that suppresses or inhibits activated lymphocytes. ... as a strong correlation between increased PD-L1 expression on tumors and a
negative survival prognosis in cancer patients. Preclinical studies indicate that ...
Hologic Releases the Results of the Cervista(TM) HPV Clinical Trials
... of the study were
as follows:
-- 100% CIN3 detection and a corresponding
negative predictive value of
100%. Patients with CIN3 are at the highest risk of ... -- The sensitivity of the test for CIN2+ was 92.8%, with a
corresponding
negative predictive value of 99.1%. Patients with CIN2 are at
risk of developing ...
Study Suggests Treatment with Paliperidone ER Significantly Improves Symptoms of Schizoaffective Disorder
... Mean modal dose for the higher dose (12mg/day) group
(b) Positive and
negative Syndrome Scale for Schizophrenia (PANSS) is a
standard rating scale used ... from absent to extreme,
and these are divided into both positive and
negative symptoms
(c) Mean modal dose for the lower dose (6mg/day) group
(d) ...
Deer Farm Industry in Michigan Issues Statement on the Negative CWD Test Results at Kent County Deer Farm
... for CWD. The
deer farm industry is issuing the following statement on the
negative CWD
test results on the rest of the herd at the Kent County Farm.
The ... received welcome news when the Department
of Agriculture released the
negative CWD test results from tested herd at
the location of Michigan's first CWD ...
New Survey Explores the Impact of Insulin Injections and Communications Between Patients and Healthcare Providers
... 14 percent of individuals surveyed felt that the
insulin injections had a
negative impact on their life (three percent
experience a major
negative impact/11 percent experience a moderate
negative impact) and more than 29 ...
Soyfoods Do Not Impact Sperm Count
... with a decrease in fertility.
Obesity may be the explanation for the
negative findings of this study.
Dr. Chavarro found high soyfood intakes are ... first to find this
correlation. The research on soy in men has not found a
negative impact on
male hormones but rather has suggested a preventive effect in ...
Pharmasset Announces Initiation of Combination Study of Clevudine and Viread(R) for HBV by French National Agency for Research on AIDS and Viral Hepatitis (ANRS)
... of both drugs administered to 150
treatment-naive hepatitis B e-antigen
negative HBV-infected patients for 96
weeks. At that time, all therapy will be ... ability to provide a sustained virologic
response in patients with eAg
negative chronic HBV infection, as either
monotherapy or in combination, offering ...
New Meta-Analysis Confirms Safety Profile for NeoRecormon in Treating Anaemia in Cancer Patients
... in the British Journal of Cancer Reports That
NeoRecormon use has no
negative Impact on Overall Survival or Tumour
Progression
A new meta-analysis of ... shows that treating anaemia with
NeoRecormon(R) (epoetin beta) has no
negative impact on survival, tumour
progression or deaths caused by blood clots, ...
IDM Pharma Announces Phase 2 Follow-Up Data Showing IDM-2101 is Well Tolerated With Positive Survival Trend in Non-Small Cell Lung Cancer Patients
... with IDM-2101, compared to a parallel
external control group of HLA-A2
negative non-treated patients.
"We continue to be encouraged by the positive ... are as follows:
-- One-year survival IDM-2101 patients versus HLA-A2
negative patients (n=72) but otherwise comparable group -- 60 percent versus ...
St. Jude Study Shows How T Cell's Machinery Dials Down Autoimmunity
... through the T cell receptor could
give rise to a subtle failing in
negative selection, which gives rise over
a long period of time to a few overly ... very big reduction in T cell
receptor signal strength to have a defect in
negative selection."
The study also showed that different T cell functions ...
Overview of Asenapine Data from Olympia Trial Program Presented at American Psychiatric Association Annual Meeting
... patients, asenapine produced 19- to
20-point reductions in Positive and
negative Syndrome Scale (PANSS) total
score and was significantly superior to ... of approximately 400 patients with acute
schizophrenia was considered a
negative trial, as the active-control
(olanzapine) differentiated from placebo ...
BiPar Sciences Expands Phase 2 Clinical Trials of BSI-201, a Novel DNA Repair Inhibitor, in Ovarian Cancer
... 15,000 annually in the United States. Patients with the
hereditable BRCA-
negative form of the disease account for about 15 percent
of the patient ... The company is currently conducting a Phase 2 trial of BSI-201 in
triple-
negative breast cancer and is collaborating with the New Approaches
to Brain Tumor ...
Pew Commission Says Industrial Scale Farm Animal Production Poses 'Unacceptable' Risks to Public Health, Environment
... in a study
released today.
Commissioners have determined that the
negative effects of the IFAP
system are too great and the scientific evidence is ... first developed simply to help increase farmer productivity
and that the
negative effects were never intended. Regardless, the
consequences are real and ...
Supportive Oncology Services Accrues One Million Cancer Patient Self-Reported Assessments
... of PROs in caring for the patient and
potentially predicting and avoiding
negative outcomes has been recognized
by the Institute of Medicine (Cancer Care for ... and we expect they will be useful in predicting and
avoiding untoward
negative events, thereby improving the patients' ultimate
health outcome."
About ...
Early Research Suggests Umbilical Cord Blood Cell Therapy May Reduce Progression of Alzheimer's Disease
... result from such
matters; decreases in asset valuations; any continued
negative effect from
adverse publicity in the past year regarding the Company's business
operations; any
negative consequences resulting from deriving, shipping and
storing specimens at a ...
Increasing Dairy Milk Production with Electrolyzed Drinking Water
... over the course of the study showed the EAU treated water was
consistently
negative for coliform organisms such as E. coli and other
bacteria. Blood chemistry ... "forecasts,"
"potential," or "continue," or similar terms or the
negative of these
terms. Although we believe that the expectations reflected in ...