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Data Available From Erbitux Phase III Study in First-Line Treatment of Advanced Lung Cancer
...metastatic squamous cell carcinoma of the head and neck for whomprior platinum-based therapy has failed. ...case of ILD reported in 796 patients with head and neck cancerreceiving ERBITUX in clinical studies. In clinical studies of ERBITUX, dermatologic toxicitie......untries for treatment of various types of head and neck cancer;and AeroLEF(TM), a proprietary, inhaled-delivery composition offree and liposome-encapsulated fentanyl in development for thetreatment of moderate to severe pain, including cancer pain. This press release may contain forward-looking statement......in American countriesfor the treatment of head and neck cancers. YM BioSciences has previously announced ...ountries fortreatment of various types of head and neck cancer; andAeroLEF(TM), a proprietary, inhaled-delivery composition of freeand liposome-encapsulated...Chi-Med Announces Positive Phase II Proof-of-Concept Data for HMPL-004 in Ulcerative Colitis
...andidate, HMPL-002, a radio-sensitizer for headand neck and non-small cell lung cancer, which is in Phase ...and China.HMPL-002, a radiosensitiser for head and neck and non-small celllung cancer, is in Phase I/II in the US and in proof-of-concept inChina. HMPL-004,......llular,endometrial, prostate, renal cell, head and neck cancers andhematological malignancies, as well as glioblastoma. The majorityof tumors expressing high levels of pAkt were high-grade, advancedstage or had other features associated with poor prognosis. HighpAkt is often seen in tumors that are resist...Solstice Neurosciences Presents Escalating Dose Study at International Congress in Istanbul, Turkey
...thefirst FDA-approved neurotoxin indicated for the neck pain andabnormal head position associated with cervical dystonia. Before administering MYOBLOC, physicians should consult the fullPrescribing Information. The most frequently reported adverseevents with MYOBLOC are dry mouth, dysphagia, dyspepsia, a...ApoCell's Cancer Predictive Index Helps Oncologists Select the Most Effective Targeted Drug Therapy
... showed the benefit of treating aggressive headand neck cancer patients with a combination of targeted mol...umors. This PDxIndex(TM) of patients with head and neck cancer showed a directcorrelation between the drug regimen and patient response. This newtechnology ...Extensive Clinical Data on Erbitux Presented at the 2007 ASCO Annual Meeting
... in first line recurrent and/or metastatichead and neck (mH&N) cancer, demonstrated that patients whor...ss thecontinuum of care for patients with head and neck cancer. ERBITUXnow offers patients a survival advantage in advanced local regionaldisease and in the...... (mCRC) and squamous cellcarcinoma of the head and neck (SCCHN). Two new studies presented at the meeting... metastatic squamous cell carcinoma of thehead and neck (SCCHN) – which is notoriously difficult totreat – first-line Erbitux combined with plat......re assessed in 112 patients with recurrenthead and neck cancer who received ADVEXIN. Overall, the percenta...ival and tumor growth control inrecurrent head and neck cancer patients. ADVEXIN has demonstratedclinical activity in a number of solid tumor types in multi......lung cancer, pancreatic,colorectal, and head & neck cancer. Approximately seventy-fivepercent of patients taking EGFRIs develop an associated skin rash.Loss of EGFR signaling has been hypothesized as a mechanism of skintoxicity in patients receiving EGFRIs. In vitro studies havesuggested that topicall......talcancer, squamous cell carcinoma of the head and neck and non-smallcell lung cancer. Merck KGaA, Darmstadt, Germany, licensed theright to market Erbitux outside the US and Canada from ImCloneSystems Incorporated of New York in 1998. In Japan, Merck KGaA hasco-exclusive marketing rights with ImClone Syst......tal cancer, squamous cell carcinoma of thehead and neck and non-small cell lung cancer. Merck KGaA is also investigating other cancer treatments,including the use of Stimuvax® (formerly referred to as BLP25Liposome Vaccine) in the treatment of non-small cell lung cancer.The vaccine was granted fast-t...... and Phase I/II studies arein progress in head and neck cancer. GenVec also uses itsproprietary adenovector technology to develop vaccines forinfectious diseases including HIV, malaria, foot-and-mouth disease,respiratory syncytial virus (RSV), and seasonal and pandemic flu.Additional information about Gen......mall cell lung,ovarian, breast, prostate, head and neck and other cancers. Commontoxicities were generally low-grade and manageable. Data from thisongoing trial were presented on Sunday, June 3, 2007, in a postertitled, "Phase 1 Trial of KOS-1584 (a Novel Epothilone) Using TwoWeekly Dosing Schedules," by ......l insolid tumors, including patients with head and neck cancer. "These data are particularly encouraging because theydemonstrate INGN 241 has clinical activity even in patients whohave failed previous therapies," said Sunil Chada, Ph.D., associatevice president, Clinical Research and Development at Int......ancing throughpre-marketing studies for head & neck and skin cancers inEurope, where it has CE Mark ac...tation, a U.S. Phase IIIpivotal study for head and neck cancer, and a Phase I/II trial forbreast cancer. Inovio's technology is protected by an extensivepat...... first line indication in advancedprimary head and neck cancer in the U.S. and Canada. CONTACT: Gavin de Windt of CEL-SCI Corporation,+1-703-506-9460 Web site: <a target="_blank" href="http://www.cel-sci.com/">http://www.cel-sci.com/ Ticker Symbol: (AMEX:CVM) Terms and conditions of use appl...Making Science Personal: Lilly Oncology to Unveil 76 Studies at ASCO 2007
...d in patients with advanced head and neck squamous cell cancer -- GEMZAR(R) (gemcitabine HCl for injection) -- Phase III Study of GEMZAR Combination in Neoadjuvant (Pre-Surgical) Breast Cancer -- Abstract # 595: June 2, 2007; 2:00 p.m. -- Neoadjuvant......2] andHYTRIN(R)[3]) which relax the muscles in the neck of the bladderand in the prostate, but have no direct effect on the prostategrowth itself, and alpha reductase inhibitors (such asPROSCAR(R)[4] and AVODART(R)[5]), which can result in somereduction of the prostate size but have a very slow onset ofac...Inovio: DNA delivery technology shows positive human results
...ancing throughpre-marketing studies for head & neck and skin cancers inEurope, where it has CE Mark ac...tation, a U.S. Phase IIIpivotal study for head and neck cancer, and a Phase I/II trial forbreast cancer. Inovio’s technology is protected by anextensi...CEL-SCI Presents Long-Term Cancer Survival Data With Multikine
...rm overall survival in aPhase II study of head and neck cancer patients. The data werepresented on May 20,...tikine that wasconducted in patients with head and neck cancer (oral squamous cellcarcinoma -- OSCC). This final Phase II clinical trial was designedto asse...Inovio Biomedical's Partners to Present New Data from Two Cancer Immunotherapy Clinical Trials
...er(R), throughpre-marketing studies for head & neck and skin cancers inEurope, where it has CE Mark ac...tation, a U.S. Phase IIIpivotal study for head and neck cancer, and a Phase I/II trial forbreast cancer. Inovio's DNA delivery partners include Merck, Wyeth...GenVec Presents Research on New Ad35 Adenovector at ARVO
... and Phase I/II studies arein progress in head and neck cancer. GenVec also uses itsproprietary adenovector technology to develop vaccines forinfectious diseases including HIV, malaria, foot-and-mouth disease(FMD), respiratory syncytial virus (RSV), and seasonal and pandemicflu. Additional information abo......ountries fortreatment of various types of head and neck cancer; andAeroLEF(TM), a unique, inhaled-delivery composition of free andliposome-encapsulated fentanyl in development for the treatment ofmoderate to severe pain, including cancer pain. This press release may contain forward-looking statements, wh...Insmed Announces Promising Results From IPLEX Phase II Myotonic Muscular Dystrophy Clinical Study
... wasting and weaknessin the hands, forearms, legs, neck and face, as well as cataractsand cardiac arrhythmias, and eventually can become totallydisabled, dying usually from respiratory or cardiac failure. Atpresent, there is no treatment to reverse most of these symptoms.For more information about myotoni......nd, migraine attacks can also involvesymptoms like neck pain or sinus pain that are not traditionallyassoc... symptoms of sinuspain/pressure (39-44 percent) or neck pain/discomfort (59-61percent). "One of the challenges in migraine treatment is helping patientsg......fmetastatic colorectal cancer, as well as head and neck cancer isongoing. Important Product Safety Information As described below, the Vectibix Prescribing Informationincludes warning language: Dermatologic toxicities, related to Vectibix blockade of EGFbinding and subsequent inhibition of EGFr-mediate......se III clinical trial in advanced primary head and neck cancerpatients in the U.S. and Canada. CEL-SCI's other products, whichare currently in pre-clinical stage, have shown protection againsta number of diseases in animal tests and are being tested againstdiseases associated with bio-defense and avian fl......non-small cell lung,prostate, gastric and head and neck cancers. In connection with aSection 505(b)(2) NDA covering ANX-514, ADVENTRX must certify thatall applicable Taxotere patents have expired prior to themanufacture, use or sale of ANX-514. About Section 505(b)(2) Section 505(b)(2) of the U.S. Food,......eg; in combination with other AEDswere somnolence, neck pain and pharyngitis. In patients 6 years ofage and older with idiopathic generalized epilepsy experiencingprimary generalized tonic-clonic seizures, the most common adverseevent associated with Keppra® in combination with other AEDswas nasophary...Aranesp ``145 Study'' Shows No Difference in Survival in Patients with Small-Cell Lung Cancer
...umor progression in patients withadvanced head and neck cancer receiving radiation therapy whenadministered to target a hemoglobin of greater than 12 g/dL, -- Shortened overall survival and increased deaths attributed todisease progression at 4 months in patients with metastatic breastcancer receiving ch...ImClone Systems Showcases Extensive Research and Development Program at the AACR Annual Meeting
...survival in patients with locallyadvanced head and neck cancer (Bonner et al, N Engl J Med.2006;354:567.) In vitro studies presented show enhanced anticancereffects with ERBITUX in combination with radiation in non-smallcell lung cancer cells and in combination with HDAC or Srcinhibition in colon cancer c......erapy for squamous cell carcinoma of the head& neck (SCCHN). The data were presented at the Annual Mee...oped totreat late stage, locally advanced head and neck cancer and iscurrently enrolling patients in its TARGET trial, a pivotal PhaseIII global clinical tr......astatic breast cancer, pancreatic cancer, head and neck cancerand hormone refractory prostate cancer. AVEO's proprietary HumanResponse Prediction(TM) Platform offers an opportunity to exploitAV-412's unique characteristics and will provide further insightinto potential clinical settings, tumor subtypes an...... and Phase I/II studies arein progress in head and neck cancer. GenVec also uses itsproprietary adenovector technology to develop vaccines forinfectious diseases including HIV, malaria, foot-and-mouth disease,and seasonal and pandemic flu. Additional information about GenVecis available at www.genvec.com ......metastatic squamous cell carcinoma of the head and neck for whomprior platinum-based therapy has failed. ...case of ILD reported in 796 patients with head and neck cancerreceiving ERBITUX in clinical studies. In clinical studies of ERBITUX, dermatologic toxicitie...... and prostate cancers, as well as lung andhead and neck cancers. Dr. Koul and colleagues at MDACC conducted the studies incollaboration with Dr. Lynn Kirkpatrick, Biomira's Chief ScientificOfficer, under a grant from the U.S. National Institutes ofHealth. About PX-866 PX-866 is an inhibitor of the phos......umor progression in patients withadvanced head and neck cancer receiving radiation therapy whenadministered to target a hemoglobin of greater than 12 g/dL; -- shortened overall survival and increased deaths attributed todisease progression at 4 months in patients with metastatic breastcancer receiving ch...Introgen Presents ADVEXIN Biomarker Data at Major Cancer Conference
...ival and tumor growth control inrecurrent head and neck cancer patients. ADVEXIN has demonstratedclinical activity in a number of solid tumor types in multiplephase 1, 2 and 3 clinical trials conducted worldwide. About INGN 241 INGN 241 is being tested in a Phase 2 clinical trial forpatients suffering f......l trials, onein ovarian cancer and one in head and neck cancer, and plans toinitiate one or more additional Phase II trials, including one incolorectal cancer in 2007. About Access Access Pharmaceuticals, Inc. is an emerging biopharmaceuticalcompany that develops and commercializes propriety products fo......etylase (HDAC) inhibitor, inpatients with head and neck cancer" will be presented in a postersession on Tuesday April 17 from 8:00 am - 12:00 pm. Dr. MissakHaigentz Jr. et al of the Albert Einstein College of Medicine, theDana-Farber Cancer Institute and National Cancer Institute/CTEP areauthors. About R...Data Available from Erbitux Phase III Study in First-Line Treatment of Advanced Pancreatic Cancer
...metastatic squamous cell carcinoma of the head and neck for whomprior platinum-based therapy has failed. ...case of ILD reported in 796 patients with head and neck cancerreceiving ERBITUX in clinical studies. In clinical studies of ERBITUX, dermatologic toxicitie...Survival Data Available From Erbitux Study in First-Line Treatment of Advanced Head and Neck Cancer
...emotherapy in recurrent and/or metastatic head and neck cancermeets primary endpoint of improving overall ...metastatic squamous cell carcinoma of the head and neck (SCCHN).The randomized, multi-center study, known as EXTREME, studied morethan 400 patients treated ...Survival Data Available from Erbitux Study in First-Line Treatment of Advanced Head and Neck Cancer
... metastatic squamous cell carcinoma of thehead and neck (SCCHN). The randomized, multi-center study, known...otherapy onoverall survival in metastatic head and neck cancer," said EricRowinsky, M.D., Chief Medical Officer and Senior Vice President ofImClone Systems....Inovio Biomedical's DNA Delivery Technology Significantly Enhances Potency of HIV DNA Vaccine
...lser(R), through pre-marketing studiesfor head and neck cancer and skin cancers in Europe, where it hasCE Mark accreditation, a U.S. phase III pivotal study for head andneck cancer, and a phase I/II trial for breast cancer. Inovio's DNAdelivery partners include Merck, Wyeth, Vical, University ofSouthampto......trials, as well asfrom a Phase 2 trial in head and neck cancer, in mid-2007. ARQ 501is an activator of the DNA damage response/checkpoint pathwayregulated by the E2F-1 regulatory protein and is the lead productfrom the Company's Activated Checkpoint Therapy (ACT) platform. The American Association for ...Other ContentscataractscataractscataractscathetercathetercathetercathetercathetercathetercatecholaminescauterizecausticcellulitephonesphonesphonescesareancesareanOther TagsWHIWHIWHIWHIWHIWHI
(Date:5/16/2008)...ugars attached to a hormone produced in the pituit...y 50 percent, a research group at Washington Unive...he change appears to alter a reproductive "thermos...stem that may one day be used to enhance human fer... reproductive hormones such as estrogen and testos...
(Date:5/16/2008)...show that CAPHOSOL ( www.caphosol.com ), an advanc...ositis (OM) and improves quality of life for cance...herapy. These data will be reported in two separa...entation and one tomorrow as a poster session, at ...ociety (ONS). These data confirm that CAPHOSOL is ...
(Date:5/16/2008)...f Forest Research presents the preliminary finding...ndscape-scale experiments on how forest management...e Blacks Mountain Interdisciplinary Research team ...rsity, Oregon State University, U.C. Riverside, Un...ety scientists collaborating in research on large-...
(Date:5/16/2008)...ree homes for their children have led to an ever-i...cterial soaps and cleaning agents. But the active ...e under scrutiny by the EPA and FDA, due to both e...closely related antimicrobials, triclosan and tric...s triclosan (TCS) has long captured the attention ...
Breaking Biology News(10 mins):Disabling mouse enzyme increases fertility 2CAPHOSOL relieves oral mucositis and improves quality-of-life in cancer patients 2CAPHOSOL relieves oral mucositis and improves quality-of-life in cancer patients 3CAPHOSOL relieves oral mucositis and improves quality-of-life in cancer patients 4Pioneering landscape-scale research releases first findings 2New study links fate of personal care products to environmental pollution and human health concerns 2New study links fate of personal care products to environmental pollution and human health concerns 3Brookings 3A Donor Perspectives on Innovative Financing for Global Health 3748 1Brookings 3A Donor Perspectives on Innovative Financing for Global Health 3748 2Pacific Valley Bank Approves 2416 7 Million Loan to Mee Memorial Hospital for Healthcare Services in South Monterey County 3745 1Pacific Valley Bank Approves 2416 7 Million Loan to Mee Memorial Hospital for Healthcare Services in South Monterey County 3745 2Pacific Valley Bank Approves 2416 7 Million Loan to Mee Memorial Hospital for Healthcare Services in South Monterey County 3745 3Concentra Offers Flu Vaccines to Keep America Working 523 1Concentra Offers Flu Vaccines to Keep America Working 523 2Stevens researchers provide new information about mass spectrometry 1269 1Stevens researchers provide new information about mass spectrometry 1269 2(Date:5/16/2008)...ire/ -- As tropical storms,continue to batter the ...,Cyclone Nargis are vulnerable to diseases and oth...stance, as exposure to the foul weather and,malnut...., "The people living in these conditions urgentl... get back on their feet," said David Meltzer,seni...
(Date:5/16/2008)...of Children Still in Danger, NEW YORK, May 16 /PR...rtising Council today announced a partnership to d...service announcements (PSAs) filmed by A-List,cele...el Madden, David,Duchovny, Tea Leoni, and Paul Rud...yclone. The Ad Council is distributing the new tel...
(Date:5/16/2008)...ire-FirstCall/ -- Nationwide,Health Properties, In...David,M. Boitano to Senior Vice President and Seni... contribution to NHP over the last several years a...versification strategy,successes. Dave has been re...ents for NHP, leveraging his vast experience and r...
(Date:5/16/2008)...l/ -- CryoCor, Inc. (Nasdaq:,CRYO), a medical devi...hythmias, announced today that on May 8, 2008, two...omplaint in the Superior Court of the State,of Cal... each member of the,Board of Directors of CryoCor,...mplaint is styled Secondido, et al. v. CryoCor, In...
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