Preclinical Data Demonstrate Ability to Regenerate an Entire Bladder With Tengion Neo-Bladder Replacement(TM)
... Neo-Bladder Replacement Structurally Similar to
native Bladder by Six Months; Data Presented at May 18 ... and a regenerative
response that emulated the
native bladder," said Dr. Bertram. "These data
join the ... -- The regenerated bladder wall showed near
native pharmacological and electrophysiological ...
MGuard(TM) Coronary Stent System Approved in Israel
... MGuard(TM) are currently underway. The
MAGICAL Trial (MGuard in SVG and
native Coronaries Trial) is being conducted
in Brazil and the GUARD Trial (MGuard ... in human subjects who are candidates
for a PCI due to a narrowing of a
native coronary artery or a bypass graft.
Since November 2007, 24 patients out of ...
Phase 3 Data Regarding Anti-RSV Antibody To Be Presented at Pediatric Academic Societies (PAS) Annual Meeting
... (AEs) were similar
between the motavizumab and the placebo groups in these
native American
infants. The mortality rates were not statistically different ... (e.g., bone marrow transplant patients). Otherwise healthy
infants in some
native American populations have demonstrated rates of RSV
hospitalization that ...
MedImmune's Motavizumab Reduced RSV Hospitalizations by 83 Percent Among High-Risk Native American, Full-Term Infants in Placebo-Controlled Phase 3 study
... trial involved 1,410 full-term
infants less than six months of age in two
native American populations. In
previous medical studies these populations were ... infectious disease, MedImmune. Motavizumab was well tolerated in these
native American infants, with
an overall incidence and severity of adverse events ...
Scientists Discover Origin of Malaria
... -- Today scientists reported that they have discovered the origin of malaria, one of the deadliest diseases of humanity. Chimpanzees,
native to equatorial Africa, have been identified as the original source of the parasite that likely moved from them to humans via mosquitoes.
An ...
Researchers Create First Targeted Knockout Rats Using Zinc Finger Nuclease Technology
... Rats via Embryo Microinjection of Zinc Finger Nucleases," (Geurts, et al.) scientists used ZFNs to knock out an inserted reporter gene and two
native rat genes without causing measurable effects on other genes. Importantly, offspring of the ZFN-mutated rats also carried the modifications, ...
First Potential Lupus-Specific Treatment in Sight
... failure. Ninety percent of the people with lupus are women, and it is two to three times more common among African Americans, Hispanics/Latinos,
native Americans, and Asians. Lupus is unpredictable and potentially fatal, yet no satisfactory treatment or cure exists.
About the LFA
The ...
CeNeRx BioPharma Obtains Rights to Novel Drug Candidate for Prevention and Treatment of Neurodegeneration Disorders
... of R&D and Chief Medical Officer of CeNeRx. "In preclinical studies, our small molecule agent CXB909 has been shown to increase the action of
native NGF, but without the pharmacokinetic and administration challenges of recombinant NGF. Most notably, CXB909 crosses the blood brain barrier, has a ...
Lupus Foundation of America Fosters the Next Generation of Lupus Researchers by Awarding Gina M. Finzi Memorial Student Summer Fellowships to Five Students
... failure. Ninety percent of the people with lupus are women, and it is two to three times more common among African Americans, Hispanics/Latinos,
native Americans, and Asians.
About the Lupus Foundation of America
The LFA is the foremost national nonprofit voluntary health organization ...
Ferring Pharmaceuticals Unveils Six-Month Efficacy Data for EUFLEXXA(R) for the Treatment of Osteoarthritis Knee Pain
... derivative (Hylan G-F20) in normal rabbit knee joints. Clin Exp Rheumatol 20, 445-454.
(4) Goomer RS, Leslie K, Maris T, & Amiel D (2005).
native hyaluronan produces less hypersensitivity than cross-linked hyaluronan. Clin Orthop Relat Res 239-245.
...
InspireMD Announces the Enrollment of the 1st Patient in the MGuard iMOS Registry, the Registry Will Enroll 1000 Patients
... in larger and less homogenous populations."
Currently, two clinical trials with Mguard(TM) are underway. The GUARD
Trial (MGuard in SVG and
native Coronaries Trial) is being conducted in
Brazil, where the Principal Investigator is Dr. Alexandre Abizaid and the
MAGICAL Trial (MGuard in Acute ...
New Analysis Evaluated Impact of Genetic Variation on Response to Prasugrel
... Y, Jang IJ, Shin SG, Bleavins MR, Williams JA, Paulauskis JD, Wilner KD. Pharmacokinetics/genotype associations for major cytochrome P450 enzymes in
native and first- and third-generation Japanese populations: comparison with Korean, Chinese, and Caucasian populations. Clin Pharmacol Ther. 2008 ...
Abbott's Market-Leading XIENCE V(R) Shows Increasing Clinical Advantages Over TAXUS(R) Express2(TM)/TAXUS(R) Liberte(TM) Between Two and Three Years
... controlled clinical trial comparing XIENCE V to TAXUS in 300 patients (223 XIENCE V patients, 77 TAXUS patients) with either one or two de novo
native coronary artery lesions. Patients from Europe, India and New Zealand were enrolled in the trial between July 5, 2005, and Nov.15, 2005.
The ...
New Hope to Beat Cancer
... (Y-TIL) trial is a phase 2 clinical trial being offered with technical support from the National Cancer Institute (NCI) in Bethesda, Md. Milwaukee
native Jeff Capstran participated in an earlier stage of this trial at NCI. Capstran had stage-four metastatic melanoma, a diagnosis that few survive, but ...
Ambrx and Merck Serono Expand Collaboration Through ARX424 Multiple Sclerosis Drug Development Alliance
... biopharmaceutical company with a broad biologics platform that allows it to create best-in-class protein therapeutics, including improved versions of
native proteins and therapeutic antibodies. Its most advanced product candidate, ARX201, is a long-acting human growth hormone drug candidate partnered ...
Franco Nuschese Tapped by Robert C. Gallo Foundation for AIDS and Virus Research
...
Nuschese is president of Georgetown Entertainment Group LLC, the management company for many diversified business enterprises. Nuschese, a
native Italian, is a 20-year veteran of hospitality conglomerates in the gaming industry and principal owner of Cafe Milano. He is a member of the boards ...
ELAD(R) Liver Support System Study Initiated at Multiple U.S. Centers
... there is a worldwide shortage of livers for transplant. ELAD was designed to address both problems since it may support regeneration of a patient's
native liver, or maintain sufficient liver function until a transplant organ is available.
VTI Chairman and CEO Terry Winters, Ph.D., said, "With the ...
Thoratec Says Interim Data Analysis Demonstrates Statistical Superiority for the HeartMate II(R) in Destination Therapy Trial
... II can pump up to 10 liters of blood per minute and is
designed to provide long-term cardiac support. The device is implanted
alongside a patient's
native heart and takes over the pumping ability of the
weakened heart's left ventricle. It is easier to implant than prior devices,
and with only one ...
Two-Year Follow-Up Data Demonstrates Preservation of Adequate Mitral Valve Area in Patients Treated with the MitraClip(R) System
... the surgical procedure pioneered by
Ottavio Alfieri, MD. The resulting double orifice has an inherently smaller
cross sectional area compared to the
native mitral valve. In a preliminary
study published in Catheterization and Cardiovascular Interventions in 2006,
Dr. Herrmann and colleagues demonstrated ...
Siemens Introduces New Standard of Care for Breast Ultrasound
... perform measurements and other routine tasks to achieve a whole new level of accuracy and efficiency. For example, syngo(R) eSieCalcs(TM)
native tracing software features proprietary border detection technology to facilitate lesion or anatomical structure boundary segmentation and syngo ...
Faith and Civil Society Leaders Call for Truth and Leadership in U.S. HIV Prevention Efforts
... pandemic.
WHO:
Serra Sippel, Executive Director, Center for Health and Gender Equity (CHANGE)
Max Siegel, Counselor for
native Health Services
Rev. William G. Sinkford, President, Unitarian Universalist Association of Congregations
Grace Sedio, Bomme Isago ...
Raptor Pharmaceuticals Provides Update on Targeting Platforms
... and researchers at Raptor will test RAP sequence variants
designed to withstand temperatures, pH and other conditions that normally
cause
native receptor complexes to fail.
Todd C. Zankel, Ph.D., Chief Scientific Officer of Raptor, commented,
"We are thrilled with the opportunity to work ...
Sanvar(R) (Debio 8609) for Esophageal Variceal Bleeding
... acetate) is a synthetic octapeptide analogue of
the naturally-occurring somatostatin hormone. It has similar
pharmacological properties to
native somatostatin, but exhibits a longer
duration of action. It is the only somatostatin analogue to have
demonstrated statistically significant benefits ...
Study Results Show Epratuzumab Provided Clinically Meaningful Reduced Disease Activity in Patients With Lupus
... Symptoms and diagnosis occur most often between the ages of 15
and 45. In the U.S., lupus is more common in African Americans, Latinos,
Asians, and
native Americans than in Caucasians.
A Lupus Foundation of America survey demonstrated the potential
economic impact of the disease, as two of three lupus ...
Just in Time for Winter, a New Berry That's Good for Your Health
... and Cranberries
NOTTINGHAM, England, Oct. 16 /PRNewswire/ -- A little known berry,
Sambucus nigra L, otherwise known as black elderberry, that is
native to
most of Europe, northwest Africa and southwest Asia, is making itself known
this year here in the United States in the form of a dietary ...
First Town Hall Meeting on Inequities in Clinical Trials to Take Place at the Harlem Hospital Center on October 20
... who participated in clinical trials to test new
cancer drugs from 1995 to 1999 were African Americans, Asian/Pacific
Islanders, Hispanics and
native Americans.
More than an issue of fairness, EDICT also documented the consequences
of not engaging communities in recruiting patients for research ...
12-Month ATLANTA Trial Data Show Sustained Benefit of Catania(TM) Stent in Treatment of De Novo Coronary Lesions
... Coronary Stent System with NanoThin Polyzene(R)-F
surface modification for symptomatic ischemic heart disease due to de novo,
obstructive lesions of
native coronary arteries. The trial was sponsored by
CeloNova BioSciences, Inc., maker of the CATANIA(TM) stent.
At 12 months, in an unusually complex FIM ...
Study Shows EUFLEXXA(R) Patients Report Significant Improvements in Osteoarthritis of the Knee Pain over a Six Month Period
... derivative (Hylan G-F20) in normal rabbit knee
joints. Clin Exp Rheumatol 20, 445-454.
(3) Goomer RS, Leslie K, Maris T, & Amiel D (2005).
native hyaluronan
produces less hypersensitivity than cross-linked hyaluronan. Clin Orthop
Relat Res 239-245.
(4) Leopold SS, Warme WJ, Pettis PD, & Shott ...
Wacker Validates Scalability of Anticalin(R) Production With E.coli Secretion Technology and Will Produce Pieris First Clinical Candidate PRS-050
... production of proteins. At the core of
the technology is a proprietary E. coli K12-strain, developed by Wacker, to
secrete recombinant proteins in
native form. Production of clinically
relevant proteins via direct extracellular secretion offers a far more cost
effective approach to biopharmaceutical ...
Results Published in the Journal 'Cancer' Demonstrate that Oral Talactoferrin Alfa is Active as Monotherapy in Previously Treated Patients with Metastatic Renal Cell Carcinoma
... Associated Lymphoid Tissue
(GALT), in infants. Talactoferrin is produced in Aspergillus niger, a
filamentous fungus, and is structurally identical to
native human
lactoferrin in all material respects, differing only in its glycosylation.
Talactoferrin is an orally administered protein that mediates ...
Positive Mid-Term Results on CryoValve(R) SG Pulmonary Human Heart Valve Presented at Western Thoracic Meeting
... defective aortic valve is removed and
replaced with his own pulmonary valve. The CryoValve SG is then surgically
implanted in place of the removed
native pulmonary valve.
The CryoValve SG pulmonary human heart valve received market clearance
from the FDA in February 2008. The market clearance was ...
Bionovo's Drug Candidate for Menopausal Symptoms Shows Effect on Neural Pathways Related to Temperature Regulation
... data were presented at the
Endocrine Society 90th Annual Meeting. Bionovo showed that, in neurons
differentiated from mouse stem cells and expressing
native estrogen
receptors, MF101, an estrogen receptor beta selective modulator, regulated
calcium levels, which are related to temperature regulation.
...
BioElectronics Announces Profitability Breakeven and Additional Clinical Trials
... medical
device as have numerous other international record for agencies.
About David G. Genecov, MD FACS FAAP
Dr. David G. Genecov is a
native of Dallas, Texas. After finishing his
undergraduate degree in the Plan II Honors Program at the University of
Texas, he completed his medical ...
IDM Pharma Announces Phase 2 Follow-Up Data Showing IDM-2101 is Well Tolerated With Positive Survival Trend in Non-Small Cell Lung Cancer Patients
... officer, IDM Pharma, Inc.
About IDM-2101
IDM-2101 includes nine CTL epitopes from four tumor associated antigens
(TAA) including two proprietary
native epitopes and seven modified, or
analog, epitopes and one universal epitope a source of T-cell help.
Tolerance to TAA, which is a failure of the ...
Study Finds Disparities in Breast Cancer Treatment Even Among Fully-Insured African-American and Caucasian Women
... Hispanic women and the second most common cause of cancer death in
Caucasian, African-American, Asian/Pacific Islander, and American
Indian/Alaska
native women.
"In an effort to improve overall quality of cancer care, it's critical
to examine disparities in treatment facing different populations," ...
BioElectronics Announces Major Clinical Trials
... medical
device as have numerous other international record for agencies.
About David G. Genecov, MD FACS FAAP
Dr. David G. Genecov is a
native of Dallas, Texas. After finishing his
undergraduate degree in the Plan II Honors Program at the University of
Texas, he completed his medical ...
CureDM's Diabetes Therapy Achieves Major Development Milestone
... HIP to improve its
bioavailability with recent dose response studies indicating that the
dosage used in man may be as much as 100-fold lower than the
native form.
HIP is a 14-amino acid human peptide derived from a specific human gene
responsible for populating the pancreas with islets, which contain ...
Statement From the Lupus Foundation of America Regarding the Release of Top-Line Results From a Study of Rituxan for the Treatment of Lupus
... are women of childbearing age (ages 15-45). Lupus is two to three
times more common among women of color, including African Americans,
Hispanics,
native Americans and Asians.
About the Lupus Foundation of America
The LFA is the nation's foremost nonprofit voluntary health
organization ...
Agennix Initiates A Randomized Double-Blind, Placebo-Controlled Phase 2 Study of Oral Talactoferrin in Severe Sepsis
... immune system, including the GALT, in infants. Talactoferrin
is produced in Aspergillus niger, a filamentous fungus, and is structurally
identical to
native human lactoferrin in all material respects, differing
only in its glycosylation.
About Agennix
Agennix is a private biotechnology company ...
Thoratec Announces FDA Approval of HeartMate II(R) for Bridge-To-Transplantation
... per minute, the
full output of a healthy heart, and is designed to provide long-term
cardiac support. The device is implanted alongside a patient's
native heart
and takes over the pumping ability of the weakened heart's left ventricle.
It is easier to implant than prior devices, and with only one moving ...