Myelin in Medical Technology

Myelin Removal Beads: Premium Efficiency for Neural Cell Separations and Antibody Stainings

... the worldwide and exclusive release of myelin Removal Beads. Myelin is a specialized membrane ... During preparation of single-cell suspensions, myelin membrane fragments represent the major ... Research Products at Miltenyi Biotec. "Removal of myelin leads to higher purity and recovery of ...

Heavy Marijuana Use May Damage Developing Brain in Teens, Young Adults

... suggest damage or an arrest in development of the myelin sheath that surrounds brain cells," said Ashtari. myelin provides a coating around brain cells similar to insulation covering an electrical wire. If myelin does not function properly, signaling within the ...

Modigene Awarded Israeli Government Grant to Support Development of Its Longer-Acting Interferon Beta

... from MS, an autoimmune neurological disorder affecting the insulating myelin layers of the brain and spinal cord. If unchecked, over time the immune system attack on myelin leads to poor coordination, severe disabilities and premature death. ...

Dirucotide Does Not Meet Primary Endpoint in Phase III MAESTRO-01 Trial in Secondary Progressive Multiple Sclerosis

... whether as a result of new information, future events or otherwise. (i) Wucherpfennig KW, Weiner HL, Hafler DA. T-cell recognition of myelin basic protein. Immunology Today, 1991; 12: 277-282. (ii) Ransohoff, R.M. Natalizumab for Multiple Sclerosis. New England Journal of Medicine, 2007 ...

Shire Enhances its Orphan Drug Pipeline With the Acquisition of a New Clinical Candidate for Metachromatic Leukodystrophy

... Symptoms and Patient Outlook Sulfatide accumulation in the central and peripheral nervous system leads to destruction of the myelin sheath (demyelination). MLD has a spectrum of disease which can arise in infants and young children with a range of symptoms, though most are related ...

Opexa Presents Tovaxin Research at Federation of Clinical Immunology Societies Annual Meeting

... poster, entitled "Identifying New Immunodominant myelin Peptides in Relapsing Remitting Multiple ... to identify several myelin protein peptides from myelin basic protein (MBP), myelin proteolipid protein (PLP) and myelin oligodendrocyte glycoprotein (MOG) as being ...

Opexa Therapeutics Reports Positive Top-line Data in Phase I/II Extension Trial with Tovaxin for Multiple Sclerosis

... demonstrated that T-cell vaccination depletes myelin reactive T-cells in peripheral blood. In the extension study patient population, the myelin reactive T-cell frequencies were reduced by 84% ... 12 months on study, respectively. Reductions in myelin reactive T-cell frequencies in the dose ...

Acorda Therapeutics Presents Data from its Phase 3 Study of Fampridine-SR in Multiple Sclerosis at the American Academy of Neurology Meeting

... but the smallest axons have a special covering of a fatty substance called myelin that acts as insulation to preserve and speed these nerve signals, much ... cord helps preserve the transmission of electricity. In MS, the myelin becomes damaged and the axon cannot effectively transmit electrical ...

Acorda Therapeutics Presents Fampridine-SR Data at ACTRIMS Meeting

... but the smallest axons have a special covering of a fatty substance called myelin that acts as insulation to preserve and speed these nerve signals, much ... cord helps preserve the transmission of electricity. In MS, the myelin becomes damaged and the axon cannot effectively transmit electrical ...

Data to be presented at AAN Meeting -Study results of drug candidate for MS

... - cells that help form myelin in the CNS. Stimulation of S1P receptors on oligodendrocytes may help limit demyelination and/or promote myelin repair. (Barske et al) In the third study, conducted in an established animal model of MS [experimental autoimmune encephalomyelitis (EAE) in ...