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mood in Medical Technology

Study Suggests New Treatment Approach May be Needed for Management of Depression in Some People With Bipolar Disorder

... is a mental illness characterized by severe mood instability that can be serious and disabling. The deep mood swings from high (mania) to low (depression) may ... along with family and friends. Drugs known as mood stabilizers have proven effective at controlling ...

Study Suggests Treatment with Paliperidone ER Significantly Improves Symptoms of Schizoaffective Disorder

... the symptoms of both schizophrenia and a major mood disorder. Patients with schizoaffective disorder ... previously prescribed anti-depressants and/or mood stabilizers during the duration of the trial, if ... to 0.008). Further, among patients with prominent mood symptoms as measured by the Young Mania Ratings ...

MJFF and Merck Serono (EMD Serono in North America) Join Forces on $2-Million Initiative to Drive Treatments for PD-Related Cognitive Dysfunction and Mood Disorders

... Parkinson's-related cognitive dysfunction and mood disorders. The funding is to be awarded under a new initiative, Cognitive Deficits and mood Disorders in Parkinson's Disease, made possible ... therapy. With the Cognitive Deficits and mood Disorders in Parkinson's Disease initiative, we ...

Large Controlled Trial of Widely Used Mood Stabilizers Demonstrates Efficacy in Pediatric Bipolar Disorder

... -- In the largest pediatric study of its kind on mood stabilizers, scientists from Cincinnati ... "Divalproex and lithium are the most widely used mood stabilizers for children and adolescents ... psychiatrist specializing in bipolar and other mood disorders at Cincinnati Children's. "Our study ...

New Data Published in Neurology Show Once-Daily Lamictal XR Significantly Reduced Partial Seizures in Patients with Epilepsy

... I disorder to delay the time to occurrence of mood episodes (depression, mania, hypomania, mixed ... of Lamictal in the acute treatment of mood episodes has not been established. Serious ... epilepsy. In clinical trials of bipolar and other mood disorders, the rate of serious rash was 0.08 ...

When It Comes to Natural Remedies for Hormonal Balance, the Proof Is in the Clinical Research

... of uncomfortable symptoms that can include hot flashes, night sweats, mood decline, and loss of libido. As common as these symptoms are, women's ... are profoundly important to a woman's health - hormones affect a woman's mood and cognitive function, they directly affect a woman's bone density, and ...

RISPERDAL(R) CONSTA(R) (Risperidone) Long-Acting Treatment Delayed the Time to Relapse in Patients with Bipolar I Disorder

... energy and ability to function. It is often characterized by debilitating mood swings from extreme highs (mania) to extreme lows (depression). Type I ... in the placebo group. The primary endpoint was time to relapse of any mood episode (depression, mania, or mixed). Time to relapse was ...

New Research Shows Nutrition 21's Chromium Histidinate Improves Markers for Mood and Carbohydrate Cravings

... brain serotonin levels. Increased serotonin levels are known to improve mood and decrease carbohydrate cravings. These results were presented at the ... a mechanism by which chromium histidinate and chromium picolinate improves mood and reduces carbohydrate cravings. The research by the U.S.D.A. provides ...

Cephalon Announces Positive Results From a Phase Two Study of NUVIGIL in Bipolar Depression

... People with bipolar disorders cycle between periods of manic or depressive mood and typically spend more time in the depressed phase of the illness. ... efficacy and safety of NUVIGIL (150 mg/day) as an adjunctive therapy to mood stabilizers in 257 patients with bipolar I disorder, who experienced a ...

Intra-Cellular Therapies Announces Successful Outcome of a Phase II Clinical Trial with ITI-007 in Patients with Sleep Maintenance Insomnia

... is common in patients with depression, bipolar disorder and other mood disorders, Alzheimer's disease (AD) and neurological disorders. For ... and in other sleep disorders such as sleep disorders in depression, other mood disorders, Alzheimer's disease and schizophrenia. ABOUT ...

Michael J. Fox Foundation Awards $2 Million for Research on Cognitive and Mood Symptoms of Parkinson's Disease

... clinical research projects under the Foundation's Cognitive Deficits and mood Disorders in Parkinson's Disease initiative, made possible by generous ... more satisfying life." The development of treatments for cognitive and mood symptoms of Parkinson's has been hindered by a lack of preclinical models ...

Current and Emerging Drugs Continue to Struggle for Patient Share in the Treatment of Major Depressive Disorder

... that a drug's long-term efficacy in preventing recurrence of depressive mood episodes in patients who suffer from major depressive disorder, is the ... Market finds that if an agent preventing recurrence of depressive mood episodes superior to that of sales-leading Wyeth's Effexor XR were to be ...

Arena Pharmaceuticals Presented Positive Phase 2a Clinical Trial Results of APD125 for the Treatment of Insomnia at 22nd Annual Meeting of the Associated Professional Sleep Societies

... in women. Common symptoms of acute insomnia are sleepiness, negative mood and impairment of performance. Chronic insomnia is often associated with fatigue, mood changes, difficulty concentrating and impaired daytime functioning. ...

New Data on SEROQUEL XR(TM) in Treatment of Both Major Depressive Disorder and Generalized Anxiety Disorder Presented at APA Annual Meeting

... in men. Unlike normal emotional experiences of sadness, loss, or passing mood states, major depressive disorder is persistent and can significantly ... scale measures the severity of a number of depressive symptoms including mood and sadness, tension, sleep, appetite, energy, concentration, suicidal ...

Arena Pharmaceuticals Initiates Phase 2b Clinical Trial of APD125 for the Treatment of Insomnia

... in women. Common symptoms of acute insomnia are sleepiness, negative mood and impairment of performance. Chronic insomnia is often associated with fatigue, mood changes, difficulty concentrating and impaired daytime functioning. ...

New Clinical Data Further Supports Chromium Picolinate's Role in Enhancing Brain Activity in Older Adults

... respect to age (72 versus 73 years), education (15.8 versus 17.3 years), mood disturbance (11 versus 4.5 Profile of mood States score), and level of memory impairment (.89 versus .63 Clinical ...

FDA Approves Cymbalta(R) for Maintenance Treatment of Major Depressive Disorder

... M.D., an internationally recognized expert on depression and other mood disorders and a distinguished scholar at Lilly. "The American Psychiatric ... norepinephrine in the brain and spinal cord are believed to both mediate mood symptoms of depression and help regulate the perception of pain. Based on ...

Arena Pharmaceuticals Announces Positive Phase 2 Clinical Trial Results of APD125 for the Treatment of Insomnia

... in women. Common symptoms of acute insomnia are sleepiness, negative mood and impairment of performance. Chronic insomnia is often associated with fatigue, mood changes, difficulty concentrating and impaired daytime functioning. About ...

Labopharm files New Drug Submission with Health Canada for novel antidepressant

... was achieved for the primary endpoint (p value of 0.012). The majority of the secondary efficacy end points, including the HAMD-17 depressed mood item, the Clinical Global Impressions Severity (CGI-S) scale, the Montgomery Asberg Depression Rating Scale (MADRS) total score and a Responder's ...

British Woman Celebrates a Year of Living Cancer-Free

... then, but I haven't been. I've been working five days a week from 9 to 5. I've been feeling fine," Ms. Scott said. Her good health and good mood mark a sharp change from how she felt when she was diagnosed with acute myeloid leukemia (AML) four years ago. AML is a cancer of the myeloid line of ...

Estrogen Getting Cool Reception From Dermatologists for Mixed Results in Improving Appearance of Skin

... it once did and that it is drier than normal. In order to treat the most common symptoms associated with menopause -- including hot flashes, mood swings and vaginal changes -- physicians often prescribe hormone replacement therapy (HRT) to boost the body's estrogen levels that drop dramatically ...

Unlikely Treatment Identified by BrainCells Neurogenesis Platform Improved Clinical Outcomes in Patients Suffering From Depression

... including neurons. "Our study results provide the first prospective clinical validation of neurogenesis as a target for the treatment of mood disorders like depression, in contrast to the traditional focus on affecting serotonin function for antidepressant drug development," said lead ...

FDA Advisory Committee Votes in Favor of Zyprexa for Two Adolescent Indications

... Toward Recovery in Bipolar Disorder. Retrieved July 17, 2008 from http://www.medscape.com/viewarticle/441618 ; NARSAD (1996). How Prevalent are mood Disorders in Children and Adolescents? Retrieved July 17, 2008 from http://www.narsad.org/news/newsletter/specialreports/archchildmood.html ...

Video: UCB Launches Vimpat(R) in the U.S. for Add-On Treatment of Epilepsy in Adults

... 1 in 500. Patients should call their healthcare provider right away if they have new or worsening symptoms of depression, any unusual changes in mood or behavior, or suicidal thoughts, behavior, or thoughts about self harm that they have never had before or may be worse than before. To report ...

No Causality Found Between Black Cohosh and Liver Problems

... been widely used in Europe and also in North America to treat menopausal symptoms including hot flashes, night sweats, occasional irritability and mood swings. While extensive research has been published on this botanical, the question of liver safety has arisen in a few isolated cases. Now, with the ...

Addrenex Pharmaceuticals Reports Positive Results in Second Phase 3 Study of ADHD Medication

... regulate the body's response to stress and other physiologic factors. An overactive adrenergic system can trigger emotional outbursts, irritability, mood swings and other debilitating symptoms. Scientists have hypothesized that the adrenergic system is overactive in a subset of children with ADHD. ...

Unexpected Side Effect: Makes You Happier

... which were designed to improve visual speed, accuracy and expanse of processing, had significantly better outcomes in key measures related to mood in one-year and five-year follow-ups. Participants in the other three groups did not have similar beneficial outcomes on this measure. The ...

Johnson & Johnson Pharmaceutical Research & Development, L.L.C. Announces FDA Filings for Paliperidone Palmitate and INVEGA(R)

... for the use of INVEGA tablets for the treatment of schizoaffective disorder as monotherapy and for use in combination with antidepressants and/or mood stabilizers. The sNDA submissions include data from two international, 6-week double-blind placebo-controlled studies that evaluated the efficacy and ...

Cymbalta(R) Significantly Reduced Osteoarthritis Knee Pain in New Study

... - 5 Dimension. About Cymbalta Serotonin and norepinephrine in the brain and spinal cord are believed to both mediate core mood symptoms and help regulate the perception of pain. Based on preclinical studies, Cymbalta is a balanced and potent reuptake inhibitor of serotonin ...

Clinical Trial Results on the Sleep-Promoting Effects of Vanda Pharmaceuticals' Circadian Regulator Tasimelteon (VEC-162) Published in The Lancet

... and to maintain sleep as compared to placebo-treated patients. The body's circadian clock plays significant roles in regulating sleep, mood as well as cardiovascular and metabolic processes.(3)(4) Circadian rhythm sleep disorders include insomnia associated with shift work (overnight, ...

Lilly Withdraws Application for Additional U.S. Indication for Cymbalta(R) for Chronic Pain

... About Duloxetine Serotonin and norepinephrine in the brain and spinal cord are believed to both mediate core mood symptoms and help regulate the perception of pain. Based on preclinical studies, Duloxetine is a balanced and potent reuptake inhibitor of serotonin ...

Raptor Pharmaceuticals to Collaborate with Centre Hospitalier Universitaire d'Angers for Phase II Clinical Trial in Huntington's Disease

... Huntington's, which results in the degeneration of certain nerve cells in the brain. The disease is characterized by uncontrollable movements and mood swings or depression, followed by dementia. About Cysteamine and DR Cysteamine Cysteamine is approved for sale by the FDA and European ...

CeNeRx BioPharma Initiates Phase II Clinical Trial of Its Novel Antidepressant Agent Tyrima(TM)

... triple-action mechanism of Tyrima elevates the levels of three key neurotransmitters (serotonin, norepinephrine and dopamine) that positively affect mood and anxiety, compared to the one or two neurotransmitters addressed by most current antidepressant drugs. This triple-action mechanism has the ...

Forest Laboratories, Inc. and Gedeon Richter Plc Announce Positive Phase II Results with the Investigational Antipsychotic Cariprazine in Patients with Acute Mania Associated with Bipolar I Disorder

... in Bipolar Disorder Bipolar disorder, also known as manic depression, is a serious medical illness most commonly characterized by extreme shifts in mood ranging from crippling "lows" (depression) to intense "highs" (mania).(1) During the manic phase of the illness, the person may feel euphoric or ...

New Data Show Efficacy of Zebinix(TM) in the Treatment of Epilepsy

... was also measured using the Montgomery Asberg Depression Rating Scale (MADRS). Zebinix(TM) demonstrated a significant improvement in depressive mood and symptoms from baseline (p<0.0001).(6) Notes to Editors About partial seizures and their treatment Epilepsy is one of the most common ...

Nationwide Survey Shows Infertility Patients Prefer ENDOMETRIN(R) Compared With Other Progesterone Supplements

... of less than two percent. ENDOMETRIN is expected to have adverse reactions to other drugs containing progesterone (breast tenderness, bloating, mood swings, irritability, and drowsiness). About Ferring Pharmaceuticals Ferring Pharmaceuticals, part of the Ferring Group, a privately ...

Addrenex Pharmaceuticals Announces Positive Phase III Clinical Results for Clonicel to Treat ADHD

... the body's adrenergic system is in overdrive, producing excessive levels of the stress hormone adrenaline. Such symptoms include emotional outbursts, mood swings, insomnia and hyperreactivity to stress. "We conducted a well-powered, randomized clinical trial to demonstrate that Clonicel may be ...

Genaera Releases Phase 1 Data and New Preclinical Data on the CNS Function of Trodusquemine (MSI-1436) at CBI Obesity Summit

... (Cmax) was observed across the range of doses studied. Values for a wide range of endocrine and metabolic biomarkers as well as evaluations of mood and cognition were also found to be stable in subjects receiving all levels of the drug or placebo during the trial. These positive Study ...

More Than 300 New Medicines Being Developed for Mental Illnesses

... of the disaster, notes a recent Harvard University study. However, in the case of Hurricane Katrina, the researchers found the contrary: Anxiety or mood disorder has been increasing by 30 percent and more. "We are releasing this report in Louisiana in view of the upcoming third anniversary of ...

CeNeRx BioPharma Finalizes Plans to Initiate Phase II Trials for Its Novel Antidepressant Agent Tyrima(TM) Using Innovative Brain Imaging Study

... triple-action mechanism of Tyrima elevates the levels of three key neurotransmitters (serotonin, norepinephrine and dopamine) that positively affect mood and anxiety. In contrast, most current antidepressant drugs affect only a single neurotransmitter. However, unlike these older MAOIs, the selectivity ...
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(Date:8/22/2014)... reductase (DHCR24) is a multifunctional enzyme ... and has neuroprotective and cholesterol-synthesizing activities. ... caused by amyloid β deposition. Dr. ... University in China constructed two recombinant ... DHCR24 expression specifically in neuronal cells. ...
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