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The International Myeloma Foundation Says Data Reported at a Global Medical Meeting in Greece Demonstrates Improved Survival for a Wide Range of Myeloma Patients

...atients todayis growing with positive results from mature studies, as well aspreliminary results from smaller trials," said Brian G.M. Durie,M.D. chairman and co- founder of the IMF. "What we are learningfrom using these novel combinations in myeloma is so promising thatour findings may become applicable to...

Apollo's human proteins boost stem cell research

...ls that are not fully developed, sogetting them to mature into specific cell types and controllingtheir growth is a tricky business. A percentage of stem cells willoften develop in the wrong way, which is a problem when researcherswant a large number of cells to grow in unison," said MrPriest. Human protei...

MaxCyte and Medinet to Present at the 13th Annual Meeting of the International Society for Cellular Therapy (ISCT) in Sydney, Australia

"Electroloading of mature dendritic cells with tumor lysatetriggers robust a.... The presentation is entitled "Electroloading of mature dendriticcells with tumor lysate triggers robust antigen-specific CTLresponse" and will discuss the ...

Human Genome Sciences Reports That a Phase 2 Study of LymphoStat-B Showed Significant Reductions in Disease Activity in Patients with Active Systemic Lupus Erythematosus

...ired for the development ofB-lymphocyte cells into mature plasma B cells. Plasma B cellsproduce antibodies, the body's first line of defense againstinfection. In lupus, rheumatoid arthritis and certain other autoimmunediseases, elevated levels of BLyS are believed to contribute to theproduction of autoanti...

Geron's Telomerase Inhibitor Cancer Drug Demonstrates Good Pharmacokinetics and Tolerability in Phase I/II Trial

...l data demonstrating the effects of GRN163Lon both mature and cancer stem cells in multiple myeloma, Geronwill initiate a clinical trial involving multiple myelomapatients," continued Dr. Colowick. "In addition, the company willbegin a fourth trial of GRN163L in combination with carboplatin andpaclitaxel in...

Fractionated Radioimmunotherapy With (90)Y-epratuzumab in Non-Hodgkin's Lymphoma Appears Safe and Active in a Phase I/II Study

...bodies targetingthe CD20 antigen on the surface of mature B-cells and B-cell tumorsas expressed by NHL cells. Immunomedics' epratuzumab is a humanizedmonoclonal antibody that targets the CD22 antigen on B-cells,including malignant B-cells. The internalizing property ofepratuzumab is believed to be well suit...

IDM Pharma Presents Preliminary Results from Phase II UVIDEM Melanoma Vaccine Clinical Trial

...ng rights to UVIDEM in melanoma. UVIDEM consistsof mature dendritic cells loaded with lysates from melanoma tumorcell lines. UVIDEM is produced in IDM Pharma GMP manufacturingfacilities in Irvine, California and in Paris, France. UVIDEM hasbeen administered to 143 patients in clinical development.Completion...

IDM Pharma Announces UVIDEM(R) and EP-2101 Data Presentations at 2007 ASCO Annual Meeting

...ng rights to UVIDEM in melanoma. UVIDEM consistsof mature dendritic cells loaded with lysates from melanoma tumorcell lines. UVIDEM is produced in IDM Pharma GMP manufacturingfacilities in Irvine, California and in Paris, France. UVIDEM hasbeen administered to 143 patients in clinical development.Completion...

Data to be presented at AAN Meeting -Study results of drug candidate for MS

...e survival and increased the number ofimmature and mature oligodendrocytes - cells that help form myelinin t...reasesoligodendrocyte numbers in both immature and mature lineages. Wepropose that FTY720P-mediated stimulation of S1P-Rs onoligodendrocytes may help limit de...

Heart Attack Patients Treated With Novel Stem Cell Therapy Experience Significant Improvement in Heart and Lung Function

... bonemarrow and have the potential to develop into mature heart cellsand new blood vessels. The MSC cells ar...re designed by nature to perform tissue repairin a mature adult. It is believed that these cells can be used inpatients unrelated to the donor, without reject...

Major Gene Study Uncovers Secrets of Leukemia

...l differentiation of immature progenitorcells into mature B lymphocytes. In ALL, the leukemic cells fail todifferentiate normally and remain blocked at an immature stage ofdevelopment. Locked in this state, the leukemic cells continue toproliferate, and this continual growth of leukemic cells eventuallykill...