Corgenix Reports New Clinical Data Correlating AtherOx Technology With Vascular Disease
... patients with autoimmunediseases such as systemic lupus erythematosus (SLE) andanti-phospholipid syndrome. The study looked at 113 SLE patients(94 with secondary anti-phospholipid syndrome and 19 without) andconcluded the measurement of anti-AtherOx is significantly betterthan conventional anti-cardiolipi......rica, Inc. and more than 1.5 million Americanswith lupus have been awaiting the preliminary findings of the...ceuticalCompany. Development of new treatments for lupus patients iscritical because many of the drugs currently used to treat thedisease are toxic and can c......e in the induction phase of patientssuffering from lupus nephritis. Although response rates were similar in... of the studyare consistent with those observed in lupus nephritis patientsreceiving immunosuppressive therapy. Overall incidence of adverseevents was compar......7, in anexperimental model of the disease systemic lupus erythematosus(SLE), can replace prednisolone, an anti-inflammatorycorticosteroid widely used in a broad range of differentinflammatory diseases, among them SLE. Several symptoms commonly associated with SLE, such as hematuria(blood in the urine) and......ed quality of life inpatients with active systemic lupus erythematosus (SLE). The52-week and 76-week result...ent. About Systemic Lupus Erythematosus Systemic lupus erythematosus (SLE) is a chronic,life-threatening disease. The Lupus Foundation of America estimates...... and severe lupus. At present, there is nocure for lupus and no new lupus drug has been approved in the U.S.in the last 40 years. The Company is conducting clinical trialswit...Immunomedics Reports Initial Clinical Results With Hpam4 For Pancreatic Cancer Therapy
... and severe lupus. At present, there is nocure for lupus and no new lupus drug has been approved in the U.S.in the last 40 years. The Company is conducting clinical trialswit...... and severe lupus. At present, there is nocure for lupus and no new lupus drug has been approved in the U.S.in the last 40 years. The Company is conducting clinical trialswit...Promising Results with Epratuzumab and Chemotherapy in Children with Acute Lymphoblastic Leukemia
... and severe lupus. At present, there is nocure for lupus and no new lupus drug has been approved in the U.S.in the last 40 years. The Company is conducting clinical trialswit......d with certain autoimmunediseases such as systemic lupus erythematosus (SLE). Current dataindicates that levels of BLyS and APRIL are elevated in patientswith rheumatoid arthritis, SLE and B-cell malignancies. Atacicepthas been shown to affect several stages of B-cell development andmay inhibit the surviva......ted to cause exacerbation oractivation of systemic lupus erythematosus. Lithium Interaction Lithium generally should not be given with thiazides. Adverse Events In clinical trials, the withdrawal rates due to adverse events(AEs) were similar with BENICAR and BENICAR HCT to placebo: BENICAR(2.4 pe......ion orprogressive liver disease, diabetes, gout or lupus erythematosus.Common side effects include dizziness, light-headedness, low bloodpressure, dehydration and stomach irritation. About King Pharmaceuticals King, headquartered in Bristol, Tennessee, is a verticallyintegrated branded pharmaceutical com......mmune disorders including thyroiditis, RA,systemic lupus erythematosus, psoriasis, pulmonary disorders(dyspnea, pulmonary infiltrates, pneumonitis and pneumonia, someresulting in patient deaths), urticaria, angioedema,bronchoconstriction, anaphylaxis, retinal hemorrhages, and cottonwool spots. In the PEGI......ovel strategy to treat autoimmune diseases such as lupus withdecreased morbidity," said Ramkumar Mandalam, ...a widerange of therapeutic applications, including lupus and otherautoimmune disorders, as well as for cancer and blood disorders,"commented Bruce Cohen, Cel......our key areas of focus are thedisease pathology of lupus and the role of B cells inautoimmunity," said Anth...the skin, joints, blood and kidneys.Treatments for lupus include anti-inflammatory drugs,antimalarials, corticosteroids and drugs approved for otherpurposes,...Critical Therapeutics Announces the Publication of New Preclincial HMGB1 Data in Nature Immunology
...at HMGB1 may contribute to the diseasepathology of lupus and supplement earlier research suggesting thata therapeutic antibody to HMGB1 may provide protection in chronicinflammatory disease. As we work in collaboration with MedImmune,Inc., to develop monoclonal antibodies (MAbs) directed towardsHMGB1, this......mmune disorders including thyroiditis, RA,systemic lupus erythematosus, psoriasis, pulmonary disorders(dyspnea, pulmonary infiltrates, pneumonitis and pneumonia, someresulting in patient deaths), urticaria, angioedema,bronchoconstriction, anaphylaxis, retinal hemorrhages, and cottonwool spots. In the PEGI...... may produce a clinical picturesimulating systemic lupus erythematosus (SLE) includingglomerulonephritis. If SLE-like symptoms occur, discontinuation ofBiDil should be considered. Residua have been detected many yearsafter discontinuation of hydralazine. Symptomatic hypotension mayoccur with even small dos...La Jolla Pharmaceutical Provides Update on Interim Antibody Results From Riquent Lupus Phase 3 Trial
... (abetimussodium), its drug candidate for systemic lupus erythematosus("lupus" or "SLE"). The updated analy...ry of renal disease and with antibodies todsDNA. A lupus renal flare is a potentially life-threateningincrease in inflammation targeting the kidney. A renal ...La Jolla Pharmaceutical Announces Positive Interim Antibody Results From Riquent Lupus Phase 3 Trial
... (abetimus sodium), its drugcandidate for systemic lupus erythematosus ("lupus" or "SLE").Analyses of inter...raging data which should attract attentionfrom the lupus community since a reduction in antibodies to dsDNAis a biomarker we associate with clinical improvem...