OPAXIO(TM) Combined with Alimta(R) Well Tolerated in Dose-Ranging Study of Patients with Advanced Non-Small Cell Lung Cancer

... at the International Association for the Study of lung Cancer (IASLC) 13th World Conference on lung Cancer. The study demonstrated that in patients with advanced non-small cell lung cancer (NSCLC), the combination of OPAXIO ...

Sosei and Vectura Announce Start of Phase III Clinical Study With NVA237

... eventually lead to a largely irreversible loss of lung function. COPD is currently the fourth most ... causing illness. The total financial burden of lung disease in Europe amounts to nearly EUR102 ... billion. Vectura also develops products for other lung pathologies and non-respiratory diseases. ...

Transave Receives $2.2 Million Cystic Fibrosis Foundation Award for Development of ARIKACE(TM)

... ARIKACE for Once-Daily Treatment of Pseudomonas lung Infections MONMOUTH JUNCTION, N.J., June 25 ... an antibiotic that aims to treat Pseudomonas lung infections in cystic fibrosis (CF) and non-CF ... trial in U.S. CF patients with Pseudomonas lung infections and a preclinical study. The company ...

Alfacell Provides Shareholder Update

... and mandate a trial in non-small cell lung cancer to prospectively demonstrate increased tumor responses when Onconase is added to a standard lung cancer chemotherapy regimen." Another ... consideration, and input from highly respected lung experts, we have decided our path moving forward ...

Two-Year Data Show Patients Receiving SIMPONI(TM) (golimumab) Experienced Sustained Improvement in Signs and Symptoms of Psoriatic Arthritis and Ankylosing Spondylitis

... colon cancer (one patient) and small cell lung cancer (one patient) in patients receiving ... prostate cancer (one patient), and small cell lung cancer (one patient) in patients receiving ... (SIMPONI 50 mg) and one due to small cell lung cancer (SIMPONI 100 mg). About the ...

Heaviest Smokers Face Greatest Risk of Death After Lung Cancer Diagnosis

... common knowledge that smoking raises risks of lung cancer. And yet researchers haven't known whether continued smoking by lung cancer patients would increase the risk of the ... the relationship between death rates from lung cancer and how much a person smoked - have found ...

Peregrine Pharmaceuticals Highlights Promising Early Data From Its Three Phase II Bavituximab Cancer Trials

... with Carboplatin/Paclitaxel in Advanced lung Cancer - - 64% Objective Tumor Response in ... chemotherapy in one Phase II trial in advanced lung cancer and two Phase II trials in advanced breast ... the following: -- Non-Small Cell lung Cancer: Bavituximab in Combination with ...

PARI Pharma Reports Successful Phase Ib Clinical Results for Inhaled Liposomal Cyclosporine A and Gains FDA Orphan Drug Designation for the Prevention and Treatment of Bronchiolitis Obliterans

... Germany. "The long-term survival rate for lung transplant patients could be greatly improved ... Phase Ib clinical trial for L-CsA studied 12 lung transplant recipients, where five patients had double lung transplants and seven patients had ...

Proteolix Presents Phase 1b/2 Clinical Data for Carfilzomib in Advanced Solid Tumor Patients at the 2009 ASCO Annual Meeting

... to disease type, including non-small cell lung cancer, small cell lung cancer, ovarian cancer and renal cancer. The ... responses observed in renal cancer and small cell lung cancer patients. A total of 55 patients are ...

Video: Phase III Study Data With Vandetanib (Zactima(TM)) in Patients With Advanced Non-Small Cell Lung Cancer (NSCLC) Presented at American Society of Clinical Oncology

... Phase III ZODIAC study in advanced non-small cell lung cancer patients, with the investigational drug ... symptoms (ZODIAC: HR 0.78, P=0.002, FACT-L lung Cancer Subscale; ZEAL: HR 0.61, P=0.004, lung Cancer Symptom Scale). Overall survival in both ...

Ascenta Therapeutics Announces Multiple Presentations on AT-101 at 2009 ASCO Annual Meeting

... Discussion, May 30, 8:00 a.m.-12:00 p.m. lung Cancer Heist R, et al. A phase I/II study of ... patients with relapsed or refractory small cell lung cancer (SCLC) after prior platinum containing ... chemotherapy. Abstract #8106; Poster Board #R14; lung Cancer - Metastatic, May 30, 2:00 p.m.-6:00 p.m. ...

PARI Pharma's Nebulized DSCG Shows Results Similar to Inhaled Steroids in Asthma Studies Presented at ATS

... in mean asthma symptom scores without a change in lung function for both groups. These results were ... has similar effects on asthma control, symptoms, lung function, and FeNO levels as compared to ICS in ... holding chamber. The study compared various lung function parameters, such as forced expiratory ...

Results of Two Phase 3 CAPACITY Studies of Pirfenidone in IPF Presented at American Thoracic Society (ATS)

... In CAPACITY 2, 83% and 90% of surviving, lung transplant-free patients completed therapy per ... IPF patients with mild to moderate impairment in lung function. The primary endpoint of both trials ... studies who were living and had not received a lung transplant, completed their Week 72 study visit. ...

Boehringer Ingelheim to Present New Phase II Clinical Data on Two Lead Oncology Compounds at ASCO 2009

... activity in advanced, second-line, non-small cell lung cancer (NSCLC) patients who have epidermal growth ... NSCLC patient population to date. About lung Cancer lung cancer is the world's most common cancer and ...

CMC ICOS Biologics and Implicit Bioscience Ltd Announce IC14 Antibody Manufacturing Agreement and Patent License

... a clinical-stage monoclonal antibody for acute lung injury (ALI). IC14 has a demonstrated safety ... on an accelerated basis." About Acute lung Injury Acute lung injury (ALI) is a severe inflammatory disease ...

Poniard Pharmaceuticals Reports First Quarter 2009 Financial Results and Provides a Corporate Update

... for the second-line treatment of small cell lung cancer, along with the independent Data ... for multiple indications beyond small cell lung cancer." Recent Clinical and Corporate Developments Small Cell lung Cancer In March, Poniard reached its ...

American Lung Association Offers Simple Tips to Protect Public Health and Minimize H1N1 Flu (Swine Flu) and Seasonal Flu Transmission

... public concern understandably grows. The American lung Association wishes to ease public concern by ... cold to H1N1 Flu (Swine Flu). "The American lung Association has been helping America respond to lung disease for more than 100 years now," said ...

Pharmaxis Announces Positive Results of Phase 3 Cystic Fibrosis Trial

... trial was to assess whether Bronchitol improves lung function as measured by a change in Forced ... a statistically significant improvement in lung function from baseline of 6.6% (p=0.001 versus placebo). lung function improved at week 6 and was sustained ...

Cystic Fibrosis - Orphan Drug Designation for Innovative Treatment Against Lung Infections by Axentis Pharma AG

... uses biocompatible lipids endogenous to the lung that are formulated into small liposomes. ... increased secretion deposits on mucous membranes. lung complications represent the most serious ... aeruginosa. Chronic inflammations then cause lung functions to become blocked. As well as the ...

Medarex Announces Preclinical Data from Multiple Research Programs Demonstrating Anti-Tumor Activity in Cancer

... membrane, that is expressed on most small cell lung cancers (SCLC). In in vitro preclinical ... and other cancers, including ovarian and lung cancer, and because of its limited expression in ... conjugate. In xenograft models of ovarian and lung cancer, MDX-1204, a fully human anti-mesothelin ...

Peregrine Pharmaceuticals Reports Positive Preliminary Data From Phase II Bavituximab Lung Cancer Trial

... locally advanced or metastatic non-small cell lung cancer (NSCLC) achieved an objective tumor ... published studies with current standard-of-care lung cancer treatments, and we are looking forward to ... Good Clinical Practices (GCP) guidelines. lung cancer is a major cause of cancer deaths ...

Genetic Source of Rare Childhood Cancer Found; Gene is Implicated in Other Cancers

... an inherited form of a rare, aggressive childhood lung cancer has uncovered important information about ... of age. The cancer progresses from air-filled lung cysts in the early stage to solid lung tumors in later stages. If detected in the ...

Prometheus and Rosetta Genomics Announce License and Collaboration Agreement

... squamous from non-squamous non-small cell lung cancer (NSCLC). When administered targeted ... asbestos exposure, from other carcinomas in the lung and pleura, a medically and legally important ... in patients diagnosed with adenocarcinoma in the lung who have been exposed to mesothelioma-related ...

American Lung Association Study to be Published in the 'New England Journal of Medicine' Finds Prescription Heartburn Medication Does Not Control Asthma Symptoms as Previously Thought

... reflux. A new study conducted by the American lung Association's Asthma Clinical Research Centers ... pain. Patients participating in the American lung Association's ACRC study were randomly given ... episodes, and there were no differences in their lung function or other asthma symptoms. These results ...

Pharmaxis Announces Milestone in Phase III Trial for Cystic Fibrosis

... of the trial is to demonstrate an improvement in lung function. Consistent loss of lung function is the leading cause of death of people ... airway surface of the lungs, and promote normal lung mucus clearance in order to ...

Poniard Pharmaceuticals Reports Fourth Quarter and Year End 2008 Financial Results and Provides a Corporate Update

... clinical trial for the treatment of small cell lung cancer, presenting data from our ongoing Phase 2 ... trial as a second-line treatment for small cell lung cancer (SCLC); ... picoplatin include a Phase 3 trial in small cell lung cancer and Phase 2 trials in metastatic ...

YM BIOSCIENCES ANNOUNCES NIMOTUZUMAB PRESENTATIONS TO BE MADE AT THE 100TH ANNUAL MEETING OF THE AMERICAN ASSOCIATION FOR CANCER RESEARCH AND EUROPEAN SOCIETY FOR MEDICAL ONCOLOGY

... These two indications - brain metastasis from lung cancer and palliative therapy in non-small cell lung cancer (NSCLC) - represent indications of high ... as more patients live longer. The incidence of lung cancer in the US is approximately 215,000 cases ...

CyberKnife Radiosurgery for Lung Cancer Sees Increased Interest and Continued Rapid Growth

... announced today significant growth in CyberKnife lung cancer treatments in calendar year 2008. The number of lung cancer patients treated with CyberKnife ... rapid adoption of CyberKnife radiosurgery, with lung being the leading extracranial indication by ...

Pharmaxis Announces New Drug Application Submission for Aridol(TM)

... and effective products to help people living with lung diseases, and we look forward to working closely ... Reference American lung Association. Epidemiology & Statistics Unit, ... disease (COPD), PXS25 for the treatment of lung fibrosis and PXS4159 for asthma. Founded in ...

Ascenta Therapeutics Announces Positive Preliminary Results with AT-101 in Docetaxel Refractory Prostate Cancer

... trials in both prostate cancer and non-small cell lung cancer, is the lead compound in Ascenta ... cause of cancer deaths among American men after lung cancer. Approximately half of all patients with ... prostate cancer and non-small cell lung cancer (with Taxotere(R) [docetaxel]), B-cell ...

Rosetta Genomics Announces Commercial Availability of its First MicroRNA-Based Diagnostic Test; Will Host Teleconference to Discuss Launch of Future Tests

... a specificity of 91% in identifying squamous cell lung cancer. Classification accuracy was measured in a ... of accurately identifying squamous cell lung cancer patients has been receiving growing ... miRview(TM) squamous classifies non-small cell lung carcinoma samples into two histological groups: ...

Research Highlights New Approaches to Prevent Blood Clots in Several High-Risk Patient Populations Including Largest Study Ever to Examine Use of Blood-Thinning Medication in Patients With Cancer

... In this study, 1,166 patients with advanced lung (279), colon (235), breast (165), ovarian (143), ... Fifteen of these events occurred in patients with lung cancer (4 percent in the nadroparin arm and 8.8 ... disproportionately higher incidence of events in lung and pancreatic cancer patients, further studies ...

NovaRx Appoints Industry Veteran as President and COO

... prove to be a safe and effective treatment for lung cancer patients. My clear priority is to ensure ... for the treatment of progressive non-small cell lung cancer. Lucanix(R), which was utilized ... are for the treatment of advanced non-small cell lung cancer, the majority of other forms of cancer are ...

Poniard Pharmaceuticals Announces Management Changes and Focus on Development and Commercialization of Picoplatin

... of picoplatin in the treatment of small cell lung cancer, currently targeted for 2010. "We ... ongoing Phase 3 registration trial in small cell lung cancer is on track, with the potential to ... include a Phase 3 trial in small cell lung cancer and Phase 2 trials in metastatic ...

American Lung Association Celebrates 101st Annual Christmas Seals Campaign

... in the mail this month, courtesy of the American lung Association. These decorative holiday stamps are ... tradition dating back to 1907 when the lung Association led efforts to conquer tuberculosis. ... Toomey President and CEO of the American lung Association. In 1907, tuberculosis ...

Video: New Survey Finds Mothers See Influenza as a Serious Health Threat, but Often Don't Get Their Families Vaccinated

... American lung Association's 2008 Faces of Influenza survey ... according to a new survey from the American lung Association. To view the Multimedia News ... Toomey, president and CEO of the American lung Association. Only 38 percent of moms say ...

Mpex Pharmaceuticals Announces Initiation of a Phase 2 Clinical Trial of Aerosol MP-376 in COPD

... duration and severity of acute exacerbations, lung function, quality of life and functional status. ... with COPD results in inflammation that causes lung damage, as well as predisposes patients to acute ... and potentially result in slowing decline in lung function, improving quality of life, and reducing ...

Pivotal Data Showed SYMBICORT(R) Improved Lung Function in Adults with COPD

... Aerosol significantly improved lung function and was well-tolerated in patients with ... SUN trials demonstrated that SYMBICORT improved lung function and was well-tolerated by study patients ... placebo.(2) -- The incidence of other potential lung infections (e.g., bronchitis) was generally ...

PTC Announces Data Showing That PTC124 Causes Statistically Significant Improvements in Chloride Channel Function in Cystic Fibrosis Patients

... patients had nonsense-mutation CF, pathological lung infection, and CF-induced pancreatic ... not yet experienced irreversible disease-related lung injury. These data in pediatric patients support ... 85 percent of the patients had chronic CF-related lung infection and pancreatic insufficiency. Study ...

Mpex Pharmaceuticals Presents New Data on MP-376 in Cystic Fibrosis

... period. In addition, FEV1, a standard measure of lung function, showed dose-related improvements ... in anaerobic environments common in the CF lung from thickened mucous layers -- Reduced ... its potency in anaerobic environments in the lung more effectively compared to other classes of ...