Lower in Medical Technology

Diabetes Gene Raises Odds of Lower Birth Weight

... 2 diabetes also predisposes children to having a lower birth weight. The finding sheds light on a ... a double whammy, in raising the risk of both lower birth weight and the development of type 2 ... called CDKAL1 , had a strong association with lower birth weight -- a finding that supports the ...

Analysis of Edoxaban Phase II Data Provides Insight Into Reduced Bleeding Events Seen in Once-Daily Dosing

... in patients taking edoxaban once a day, lower minimum concentrations and fewer bleeding events ... the most bleeding events. It may be that reaching lower Cmin levels with edoxaban once-a-day permits some ... and that may be the reason why bleeding rates are lower with once-daily dosing." "This Phase II ...

Results From Drug Trials and New Risk Factors Announced at International Alzheimer's Conference

... drugs are tested for how much they can lower beta amyloid levels. News Cases of ... May Raise Alzheimer's Risk; Moderate Alcohol May lower It Two studies from ICAD 2009 looked ... with PTSD. A second study suggests lower Alzheimer's risk among adults who consume ...

PTSD Associated With Higher Alzheimer's/Dementia Risk; Moderate Alcohol Consumption May Lower it

... with post-traumatic stress disorder (PTSD), and lower Alzheimer's risk among adults who consume ... Alcohol Intake Is Associated With Nearly 40% lower Risk of Dementia Moderate alcohol intake, ... (1-2 drinks per day) was associated with a 37% lower risk of dementia in participants with normal ...

Two-Year Data Show Patients Receiving SIMPONI(TM) (golimumab) Experienced Sustained Improvement in Signs and Symptoms of Psoriatic Arthritis and Ankylosing Spondylitis

... Joints of the hands, wrists, knees, ankles, feet, lower back and neck are commonly affected. Psoriasis ... is a prescription medicine. SIMPONI(TM) can lower your ability to fight infections. There are ... like shortness of breath or swelling of your lower legs or feet. Rarely, people using TNF ...

Studies Show AFRESA(R) Controls Post-Meal Sugar Levels With Less Weight Gain and Hypoglycemia Risk for Diabetes Patients

... with the added benefits of less weight gain and lower risk of hypoglycemia." AFRESA is a novel, ... baseline after a meal challenge was significantly lower in the TI+G group (37 vs. 54 mg/dL; p<0.0001). ... +/- 4.56, CI=0.0022) values were significantly lower with AFRESA than with RAA. Patients in the AFRESA ...

Paclitaxel Poliglumex (OPAXIO(TM)) Added to Cisplatin and Radiation Produces 45% Pathologic Complete Remissions in Patients With Esophageal Cancer

... Annual Meeting, patients with cancer of the lower esophagus had evidence of a high pathological ... therapy with 5-FU and cisplatin due to the lower incidence of severe gastrointestinal toxicity. It ... being reported in this study combined with the lower than expected gastrointestinal and other severe ...

PARI Pharma Reports Successful Phase Ib Clinical Results for Inhaled Liposomal Cyclosporine A and Gains FDA Orphan Drug Designation for the Prevention and Treatment of Bronchiolitis Obliterans

... target sites in the lung, which should lead to lower side effects than associated with systemic ... respectively. These results are significantly lower compared to oral therapy. In comparison, oral CsA ... [Knoop 2003]. L-CsA's favorable and significantly lower pharmacokinetic values were obtained for both ...

Lower Extremity Peripheral Vascular Stent and Balloon Catheter Markets to Exceed $180 Million in Europe by 2013

... focus, and new drug-eluting technologies to drive lower extremity procedures in Europe , according to ... the number of endovascular procedures that treat lower extremity peripheral artery disease in Europe is ... these factors will drive the markets for lower extremity PV stents and percutaneous transluminal ...

SYNTAX Analysis Finds Treatment With TAXUS(R) Express2(R) Stent System More Cost Effective Than Bypass Surgery in Patients With Complex Coronary Artery Disease

... Total medical costs at one year were also lower with PCI. Analysis of the data was presented by ... stays, increased quality adjusted life years and lower total costs. When coupled with safety and ... total medical costs for PCI were 25 percent lower than CABG at one year (8,295 pounds Sterling PCI ...

Results of Two Phase 3 CAPACITY Studies of Pirfenidone in IPF Presented at American Thoracic Society (ATS)

... dose of 1197 mg pirfenidone, respectively. The lower dose of pirfenidone in CAPACITY 2 was included to ... of IPF-related deaths during treatment was also lower among patients treated with pirfenidone. ... administered in three divided doses. The lower dose of pirfenidone in CAPACITY 2 provided safety ...

Metabolic Solutions Development Company Announces Preliminary Results from Phase IIa Clinical Trial

... Results show improved insulin sensitivity and lower glucose levels without the side effects of ... MSDC-0160, can improve insulin sensitivity and lower blood glucose levels in humans without the side ... (TZD) can improve insulin sensitivity and lower glucose similar to a traditional TZD," said Dr. ...

Journal of American College of Cardiology Article Reports Fewer Repeat Procedures With Boston Scientific's TAXUS(R) Liberte(R) Stent

... (R) Paclitaxel-Eluting Stent had numerically lower incidences of repeat procedures to treat ... Stent demonstrated a statistically significant lower restenosis rate compared to the Endeavor Stent, ... Liberte Stent had an approximately 23 percent lower restenosis rate at two years compared to the ...

The Injured Obese Child: Let's Give Him Some Ankle Support

... Obese Children are More Likely to Suffer from lower Body Injuries CINCINNATI, May 5 ... children are significantly more likely to have lower body injuries, such as in their ankles and legs. ... Societies in Baltimore. "The most common lower body injuries were sprains," said Wendy ...

Lexicon Pharmaceuticals Provides Clinical Pipeline Update and Reports 2009 First Quarter Results

... 2008. The decrease was primarily attributable to lower salary and benefit costs, due to reductions in ... in part by associated severance costs, as well as lower external research expenses. General and ... 2008. The decrease was primarily attributable to lower salary and benefit costs, due to reductions in ...

New Body of Research Suggests Statin Use Benefits Multiple Areas of Urologic Health

... that the use of statins--commonly prescribed to lower cholesterol--may benefit men with prostate cancer, erectile dysfunction or lower urinary tract symptoms (LUTS). Several key ... including adverse tumor features and lower risk of positive surgical margins. ...

Processed Tomato Products May Protect Against Inflammation, According to a Study Presented at the Experimental Biology Meeting

... products has been consistently associated with a lower risk of several types of cancer and coronary ... tomatoes was associated with significantly lower serum C-reactive protein. C-reactive protein is a ... experienced a C-reactive protein level that was lower in response to the high-fat meal. High-tomato ...

Glycotex' Investigational Compound GLYC-101 Achieves Accelerated Wound Closure Based on Interim Analysis

... carbon dioxide laser skin resurfacing on the lower eyelid area. The interim analysis was ... 0.1%, GLYC-101 1.0%, or placebo gel on one lower eyelid, and a different test article on the other lower eyelid applied topically to the laser-ablated ...

New Data for Abbott's TRILIPIX(R) (fenofibric acid) in Combination with Rosuvastatin Calcium Shows Improvement on Key Lipids for Cholesterol Management

... medicine that can be used along with diet to lower triglycerides and LDL (bad) cholesterol, and ... TRILIPIX can also be used along with diet to lower triglycerides and increase HDL cholesterol in ... more aggressive management of lipids, including a lower LDL goal for many patients, as well as more ...

SYNTAX Analysis Finds Treatment With TAXUS(R) Express2(TM) Stents More Cost Effective Than Bypass Surgery in Many Patients With Complex Coronary Artery Disease

... providing more quality-adjusted life years and lower net medical costs than CABG. For patients with ... study showed that total medical costs were $5,693 lower for PCI than for CABG for the initial ... for CABG) (p<0.001), and remained $3,590 lower for PCI than CABG through 12-month follow-up ...

ViroPharma Submits Comments on Vancocin(R) Draft Bioequivalence Guidance

... with CDI. By focusing exclusively on the lower GI tract, the December 2008 Draft Guidance fails ... infections - which occur in both the upper and lower GI tract. OGD's Q1Q2 sameness standard is ... after antibiotic therapy, can colonize the lower gastrointestinal tract where it may produce ...

Harvard Study Shows Folic Acid, B Vitamins in Animi-3(R) May Prevent Vision Loss

... B vitamins, including B6, B12, and folic acid, lower risk of developing age-related macular ... approximately 34 percent of the women had a lower risk of developing any type of AMD, while 41 percent had a lower risk of more severe forms of AMD. "What's ...

Boston Scientific Submits Final Modules to FDA for Approval of Second-Generation Small Vessel and Long Lesion Stents

... Liberte Long Stent. "In the ATLAS study, lower target lesion revascularization (TLR) rates contributed to a significantly lower rate of MACE, including heart attacks, with the ... TAXUS Liberte Atom Stent reported significantly lower nine-month angiographic in-segment late loss ...

Why Wait for an Anti-Aging Drug? Researchers Interviewed on CBS-TV's 60 MINUTES Discover Longevinex(R) Nutriceutical Matrix Activates 9-Fold More Longevity Genes than Plain Resveratrol

... longevity genes than plain resveratrol at a far lower dose than previously reported. (Photo: ... doses that shortened the lives of lab animals. lower doses, like those found in 3-5 glasses of red ... the fact the red-wine-drinking French exhibit 30% lower mortality rates from heart disease despite their ...

ISTA Pharmaceuticals Announces Positive Results for Phase IIb Study of Ecabet Sodium

... II clinical trial studying the potential of a lower strength of Xibrom to treat the signs and ... eye disease in the first half of 2009. Once this lower strength Xibrom trial is completed, we will make ... the results of future or ongoing studies with lower strength Xibrom, ISTA's intention to select one ...

Longevity Seekers Advised to Consume Modest Doses of Red Wine Molecules in Dietary Supplements (Longevinex(R)) Rather than Mega-Dose Resveratrol Alone

... wine drinkers have cardiac mortality rates 30% lower than North Americans despite their high-calorie, ... studies show modest doses of red wine lower mortality rates over abstention or ... heard about the 2008 report, says Sardi. lower dose resveratrol accompanied by an array of other ...

ASGE Urges Patients to Seek a Qualified Endoscopist Before Undergoing a Colonoscopy for Colorectal Cancer

... study finds that colonoscopy is associated with lower death rates, but raises concerns about detection ... found that colonoscopy is associated with lower death rates from colorectal cancer, however, the ... safe procedure that examines the lining of the lower intestinal tract called the colon or large ...

K-State Researcher Finds Correlation Between Childhood Obesity and Asthma

... children with higher levels of body fat and lower levels of physical activity had greater amounts ... found that the higher the body fat and the lower the level of activity of the child, the more ... students that had higher levels of body fat and lower levels of activity, Rosenkranz said it is ...

New Keppra XR(TM) Data Highlight Its Role for Patients with Partial-Onset Seizures

... patients taking Keppra XR once-daily had lower rates of some adverse events versus levetiracetam ... experienced statistically significantly lower rates of adverse events related to nervous system ... Keppra XR-treated patients reported numerically lower rates of psychiatric disorders (i.e., ...

Studies Examine Quality of Care for Hospitalized Sickle Cell Disease Patients and Effective Methods for Detecting Risk of Stroke in Children With This Disorder

... and several other factors, confirmed that a lower volume of sickle cell patients was associated ... with length of hospital stay or cost; however, lower status trended toward higher mortality in adult ... the risk of stroke, to determine whether lower hemoglobin saturation was associated with a ...

Observational Study Finds Changes in Medicare Reimbursement for Erythropoiesis-Stimulating Agents Associated With Increased Need for Blood Transfusion

... 1.1 vs. pre-NCD 0.5, p= 0.0089). Significantly lower mean Hb levels (g/dL) were reported in the ... agents (ESAs) to target higher versus lower hemoglobin levels (13.5 vs. 11.3 g/dL; 14 vs. 10 ... when administered ESAs to target higher versus lower hemoglobin levels (13.5 vs. 11.3 g/dL; 14 vs. 10 ...

More Than 200 Abstracts at ASH and SABCS Reveal Potential Compelling Patient Benefits From Novartis Oncology Current and Pipeline Therapies

... to tolerate the reintroduction of Gleevec at a lower dose with or without concomitant corticosteroids ... therapy with Exjade may be reinitiated at a lower dose followed by gradual dose escalation, if the ... Exjade may be interrupted. Reintroduction at a lower dose with escalation may be considered in ...

Dronedarone (Multaq(R)) Reduced the Incidence and Duration of Hospitalization in Patients with Atrial Fibrillation

... of dronedarone, previously demonstrated in lower risk populations studied in the EURIDIS(1), ... of CV hospitalization or death was 26% lower for those receiving dronedarone (p=0.096). These ... than 50 mm or left ventricular ejection fraction lower than 40 percent). Patients with decompensated ...

Study Suggests Treatment with Paliperidone ER Significantly Improves Symptoms of Schizoaffective Disorder

... to patients on placebo (p=0.003). The lower dose group [5.7 mg/day](c), however, did not show ... more patients in both the higher and lower dose groups achieved overall response (defined as ... negative symptoms (c) Mean modal dose for the lower dose (6mg/day) group (d) Clinical Global ...

Grapes May Aid a Bunch of Heart Risk Factors, U-M Animal Study Finds

... that received the grape-enriched diet powder had lower blood pressure, better heart function, ... hydrazine, along with a salty diet also had lower blood pressure, but their hearts were not ... In the meantime, Bolling says, people who want to lower their blood pressure, reduce the risk of heart ...

Abbott's XIENCE V(TM) Drug Eluting Stent Outperforms TAXUS(R) in Key Efficacy and Safety Endpoints Out to Two Years

... Confirms Patients Treated with XIENCE V Are at lower Risk of Experiencing Death, a Heart Attack or a ... years. XIENCE V also demonstrated significantly lower clinical events rates than TAXUS in the key ... subgroup analysis, we saw encouraging trends of lower event rates between one and two years for ...

Taxus Atlas Studies Reinforce Safety and Efficacy of Boston Scientific's Next-Generation Taxus Liberte Stent

... (TVR) rate through three years was significantly lower for the TAXUS Liberte Stent group (6.1 percent ... difference was driven mainly by the 67 percent lower rate of target lesion revascularization (TLR) in ... groups. The study also reported a significantly lower adjusted rate of ARC definite/probable stent ...

Bionovo's MF101 Shows Statistically Significant Improvement in Sleep Disturbance from Hot Flashes

... to the placebo (p=0.05). Women randomized to the lower dose of MF101 also had a greater reduction of ... time awakenings from hot flashes compared to the lower dose and the lower dose was more effective than placebo. These data ...

Resveratrol Longevity Science Makes Dramatic U-Turn, But Resveratrol Supplements Remain Unchanged

... Resveratrol, Sirtuin1 gene Target Discredited; lower Dose, Array of Small Molecules ... fed a plain standard calorie diet. Animals on the lower dose (360 milligram human equivalent) lived ... gene activators would be required, a much lower dose of resveratrol (100 milligrams human ...

Nation's Foremost Health Care Leaders Kick Off Summit Focused on Zero-Tolerance Approach to Hospital-Acquired Infections

... for an October deadline when Medicare will lower reimbursement rates for certain preventable ... health care industry. As of Oct. 1, Medicare will lower or eliminate reimbursement for 11 ... the 11 preventable conditions that will receive lower or no Medicare reimbursements, the top three most ...