lipids

Low-Density Cholesterol Subfractions: Not all LDL-C Particles are Created Equal

...of cardiac events. In 1988, a study on cholesterol lipids and CAD noted that 75 percent of patients who suffer myocardial infarctions have normal levels of HDL-C and LDL-C (Castelli, Can J Cardiol 1988 4A:5A). These insufficiencies have led to the revision of the guidelines and additional studies to measu...

Lpath Demonstrates 'First-in-Class' AMD Results With Its Lead Drug Candidate, Sphingomab

...ieldof medical science whereby bioactive signaling lipids are targetedfor treating important human diseases. Lpath's lead productcandidate, Sphingomab, is a monoclonal antibody against a validatedcancer target, sphingosine-1-phosphate (S1P), and has demonstratedcompelling results in preclinical studies agai...

Data Presented at ASH Demonstrate Nebivolol Lowers Blood Pressure as Long-Term Monotherapy and in Combination Therapy

...clinically significant changes in glucose or lipids were seen with nebivolol monotherapy during the study. -- "Addition of the Beta-Blocker Nebivolol to Ongoing Therapy in the Management of Mild-to-Moderate Hypertension" by Alan H. Gradman, MD, Chief, Division of Cardiovascular Diseases...

Safety Analyses of Clinical Data for Bifeprunox in Patients with Schizophrenia Showed a Favorable Weight and Lipid Profile, Similar to Placebo

... profile similar to placebo. -- Weight, BMI and lipids were assessed in patients with acute exacerb...e in six-week studies, and body weight and lipids in all studies. * In patients who received bifeprunox, weight decreases and improvemen...

Study Presented at ACC Shows Treatment With ISIS 301012 Added to Statins for Only 5 Weeks Results in 75% of Patients Achieving LDL-C Levels Less Than 100 mg/dL and 50% of Patients Achieving LDL-C Levels of Less Than 70 mg/dL

...th similarly favorable effects on otheratherogenic lipids NEW ORLEANS and CARLSBAD, Calif., March 26, 2007/PRNewswire-FirstCall/ -- Isis Pharmaceuticals, Inc. announced newresults from its Phase 2 clinical trial of ISIS 301012coadministered with statins presented today at the of CardiologyAnnual Scientific ...