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HEALTHPOINT-Sponsored Venous Leg Ulcer Clinical Trial Enrolls First Subject for Second Phase II Study

... for the treatment of venous leg ulcers. HP802-247 is a topical spray containing ... secondary to venous hypertension, venous leg ulcers are increasingly common, are costly, and ... Slade. "Based on an estimated 2.5 million venous leg ulcers in the United States alone and actual ...

Video: ev3 Inc. Announces First Patient Enrollments in DEFINITIVE LE Post-Market Study

... will evaluate one-year patency in patients with leg pain (claudication) and one-year limb salvage in patients with critical leg ischemia (CLI) and include third party review of ... Peripheral arterial disease (PAD) occurs when leg arteries become narrowed or blocked by plaque. ...

Healthpoint Initiates Phase II, Dose-Finding Study to Evaluate Effectiveness of a Unique Cell Based Therapy in Venous Leg Ulcers

... investigating the efficacy of HP802-247 in venous leg ulcers. HP802-247 is a topical spray containing ... to placebo plus standard care, in healing venous leg ulcers over a 12-week treatment period. ... subjects 18 years of age and older with venous leg ulcers of at least 6 week's, but not more than 24 ...

March 2009 Mayo Clinic Health Letter Highlights Knee Repair Surgery, Anxiety Disorder and Preventing Blood Clots

... is reconstructed with a piece of tendon from the leg or with a tendon from a donor cadaver. With ... also creates risks. Trauma or a fracture in the leg area or pelvis puts patients at especially high ... area of the affected leg. Typically only one leg is affected. ...

MEDIHONEY(TM) Dressings Shown to Help Improve Outcomes of Non-Healing Venous Leg Ulcers in Recent Case Series

... of a case series on eleven non-healing venous leg ulcers. These wounds had previously failed to ... Honey (MEDIHONEY) in Recalcitrant Venous leg Wounds: A Preliminary Case Series" was published ... of MEDIHONEY - particularly in non-healing venous leg ulcers - continues to grow. This case series ...

APTA Supports Surgeon General's 'Call to Action' to Prevent Deep Vein Thrombosis and Pulmonary Embolism

... called pulmonary embolus. The symptoms of leg DVT include swelling in one or both legs and ... symptoms experienced by people who fly, including leg cramping, toe cramping, and general lower-body ... aisle of the plane every hour or so to work the leg muscles and ease the back -- that is, if the ...

Pivotal National Trial Uses Newest Interventional Radiology Treatment to Bust Blood Clots in Legs

... with DVT (the formation of a blood clot in a leg vein). PTS, a common irreversible complication of ... to the veins, resulting in debilitating chronic leg pain, swelling, fatigue and/or skin ulcers. ... in the pooling of blood in the leg, chronic leg pain, swelling and fatigue and sometimes skin ...

Derma Sciences' MEDIHONEY(TM) Proven to Speed Healing in Stalled Leg Ulcers

... the healing rates of stalled venous leg ulcers. Prior to this study, no other advanced ... been shown to improve healing rates of leg ulcers. Physicians treat over 4 million leg ulcers in the US per year, at a cost exceeding ...

Randomized Controlled Clinical Trial Shows Derma Sciences MEDIHONEY(TM) Eradicates MRSA From Chronic Venous Ulcers

... and controlled clinical trial, looked at venous leg ulcers that had been proven to be non-healing ... paper "Bacteriological Changes in Sloughy Venous leg Ulcers Treated with Manuka Honey or Hydrogel: an ... of a large-scale randomized controlled trial on leg ulcers. Derma has two products in development: ...

Edwards' Resilient Trial Demonstrates Statistically Superior Results for Treating Peripheral Arterial Disease in the Leg

... - Arterial Blockages in the leg are Estimated to Affect 8 Million Americans ... are the major circulatory channels for the upper leg and knee. "The RESILIENT Trial is a randomized, ... is the major artery providing blood flow to the leg and extends behind the knee as the popliteal ...

Video: New Research Discovers Independent Brain Networks Control Human Walking

... are separate adaptable networks controlling each leg and there are also separate networks controlling leg movements, e.g., forward or backward walking. ... contrary to the currently accepted theory that leg movements and adaptations are directed by a ...

Clinician Reports Fast Healing of Intractable Wounds Using MEDIHONEY(R)

... South Florida, revealed details of a recently concluded 11-patient venous leg ulcer (VLU) case series involving the use of Derma Sciences' MEDIHONEY(R). ... and was the focus of a positive large-scale randomized controlled trial on leg ulcers. Derma's recently FDA cleared BIOGUARD(TM) Barrier Dressing is the ...

NHS National Innovation Centre Cites VNUS Closure(R) Procedure as Select Innovative Technology

... pressure in the legs as a result of venous reflux and faulty valves in the leg veins. Left untreated, venous reflux can lead to painful varicose veins, ... the lower limbs, and skin problems, such as itching, redness, eczema, and leg ulcers. For the past century, the traditional treatment for ...

Texas Back Institute Leads Way in New Facet Joint Clinical Trial

... is a spinal implant intended for the treatment of patients with chronic leg and/or back pain caused by spinal stenosis. It's part of a category of ... compresses the spinal cord and nerve roots that are causing lower back and leg pain. Specifically, TFAS replaces the degenerated facet joints with an ...

Sangamo BioSciences Announces Presentation of Phase 1b ZFP Therapeutic Data at American Diabetes Association Meeting

... cohort. Cohorts 1 and 2 will receive a single treatment of 30 mg into one leg or 60 mg (30 mg in each leg) of SB-509, respectively, by intramuscular ... and this infection may spread to the bone, necessitating amputation of the leg or foot. More than 60 percent of non-traumatic lower-limb amputations in ...

Sangamo BioSciences Provides Update on Diabetic Neuropathy Clinical Programs

... nerves" or unmeasurable nerve conduction velocity measurements in the leg showed recovered and improved NCV after a single treatment with SB-509 and ... and this infection may spread to the bone, necessitating amputation of the leg or foot. More than 60 percent of non-traumatic lower-limb amputations in ...

Large, Long-Term Study Shows Avandia Has No Increased Overall Cardiovascular Risk Compared to Other Commonly Used Diabetes Medicines

... Avandia, including bone fractures, which were higher in the group randomized to Avandia and were seen mostly in the bones of the arm, hands, lower leg and feet, and predominantly in women. Among patients randomized to Avandia, the results for the following prespecified secondary endpoints also ...

Back to Normal: Surgery Improves Outcomes for Spine Patients

... the aging process. More Information : SPORT is the first comprehensive study to look at different ways of treating low back and leg pain and how effective they are for patients. The trial was funded by the National Institutes of Health (NIH) in recognition of how prevalent back ...

Glycerin Proven to Improve Bruising and Swelling Caused By Trauma to Skin

... is bruising. I have seen a significant decrease in bruising after treatments with an application of Bruise Relief(TM). Post-procedural Botox and leg vein injections (sclerotherapy) may also benefit from this single post-procedural application." Glycerin, a humectant, attracts water and helps ...

New Study Using Combination of Bioengineered Skin and Stem Cells Shows Promise in Treatment of Non-Healing Wounds

... how bioengineered skin plays a critical role in this procedure. "The concept of using bioengineered skin to heal difficult wounds, such as leg and foot ulcers, previously has been shown to be effective for chronic wounds but, in our experience, has not by itself been consistently useful in ...

New Cancer Treatment Stops Aggressive Sarcomas

... (MFH) that arose in the largest bone of his leg. The cancer spread throughout his lungs, despite aggressive surgery that replaced most of his leg with metal implants. The second patient was losing a battle with desmoplastic small round cell tumor (DSRCT), a very rare and aggressive cancer. ...

Early Switch from IV to Oral Meds Is Effective for Children with Acute Bone Infection

... Typically caused by the common bacteria Staphylococcus aureus , osteomyelitis usually appears as a fever with some discomfort in a child's leg or arm resulting from the bone infection. The average age of children with the condition is five years. The traditional treatment has been to ...

Wrist Access Safer, Easier for Many Patients Undergoing Minimally Invasive Treatment of Blocked Heart Arteries

... make it safer and easier on patients. To access the arteries, an interventional physician makes a small incision in the groin at the top of the leg and advances a thin tube (catheter) through the femoral artery to the site of the blockage. A tiny balloon is then inflated to open up the artery, ...

VA-NIH Study Offers Hope for Parkinson's Patients

... improvements in symptoms such as tremors or stiffness. Many were also developing side effects from the drugs, such as involuntary face, arm or leg movements. Researchers followed the patients for six months, finding: Patients who received DBS gained an average of 4.6 hours ...

Do You Know You're Having a Stroke?

... stop a stroke from spreading and greatly limit damage. Stroke symptoms include: * Sudden numbness, weakness, or paralysis of your face, arm or leg -- usually on one side of the body * Sudden difficulty speaking or understanding speech (aphasia) * Sudden blurred, double or decreased ...

Kleinert Kutz Hand Surgeons Perform Fifth U.S. Hand Transplant in Record Time at Jewish Hospital Hand Care Center

... for all of our hand transplant patient's pioneering efforts, which help us constantly improve the way we help amputees and reconstruct arm and leg defects." Breidenbach stated, "With each patient we want to do two things -- improve the way we reconstruct the defect and decrease the ...

Facet Solutions Announces Completion of 6 Month Follow-Up in US Pilot Study

... Study. The results show a 78% reduction in Oswestry Disability Index (ODI) scores, and an 80% reduction in Visual Analog Scores (VAS) for symptomatic leg pain. Geoff Pardo, President & CEO for Facet Solutions, added, "We are very pleased with these early results, which thus far not only demonstrate ...

338 Patient Pivotal Trial Demonstrates Safety and Effectiveness of Polidocanol Sclerotherapy Product for Varicose Vein Treatment

... Isotonic saline (a placebo control). Patients were followed for 26 weeks (6 months) with standardized photography of a defined 10x10 cm area of the leg at baseline, 12 weeks and 26 weeks. These photographs were rated by the treating physicians and two blinded evaluators, which served as the basis for ...

Diffusion Pharmaceuticals Announces Initiation of a Phase I/II Clinical Trial in Patients with Peripheral Arterial Disease (PAD)

... factor to morbidity and mortality worldwide. PAD is a manifestation of systemic atherosclerosis in which arterial blockages lead to decreased leg blood flow. During exercise or walking this decreased blood flow and the corresponding decrease in available oxygen frequently lead to pain and ...

Omeros Announces Publication of Clinical Results for OMS103HP in Arthroscopy: The Journal of Arthroscopic and Related Surgery

... were monitored for safety, and efficacy endpoints assessed over the 30-day postoperative period included measurements of knee function and motion, leg muscle strength, pain and return to work. Results of the study demonstrated a statistically significant improvement in knee function, range of ...

New Minimally Invasive Surgical Procedure Restores Quality of Life in Patients With Potentially Debilitating Spinal Condition

... the canal, squeezing and irritating the nerves that branch out from the spinal cord. This compression causes patients to experience low back pain, leg fatigue and pain, and, in severe cases, a significant reduced capacity for physical activity, including walking. Designed to remove the bone and ...

Halozyme Therapeutics Announces Positive Findings With Pegylated Enzyme in Prostate Cancer Models

... metastases. For the HA-producing xenograft PC3 model, animals received an intramuscular inoculation with PC3 prostate carcinoma cells in the hind leg in order to generate tumors with high IFP. When tumor volume reached 400-500 mm(3), a high tumor burden, animals were randomized to receive one of ...

Dr. Christopher Moore to Form ProDerm LP to Fund CVBT Wound Healing Trial

... "I am extremely impressed with CVBT's wound healing drug, which I believe has the potential to treat patients for diabetic ulcers and venous stasis leg wounds better than any of the current products on the market. The active pharmaceutical ingredient (API) is truly remarkable," said Dr. Moore. PDLP ...

Cardiovascular Researchers Use MEDIHONEY(TM) on Sternal Infections Following Open-Heart Procedures

... product has been shown to be effective in a variety of wounds and burns, and was recently the focus of a large scale randomized controlled trial on leg ulcers. For more information about Derma Sciences, Inc., visit its home page on the Internet at http://www.dermasciences.com . Contact: Derma ...

Alseres Pharmaceuticals Announces 12 Month Interim Results from the Phase I/IIa Cethrin(R) Clinical Trial in Acute Spinal Cord Injury

... A component of this scale is the assessment of change in Motor Score. The measurement is made by assessing five muscle groups in each arm and leg on a 0-5 point scale for a total of 100 motor points. Using this assessment, the total change in motor function can be measured. The Clinical ...

Innocoll Announces Dosing of First Patient in US Phase 2 Clinical Trial to Investigate CollaRx(R) GENTAMICIN TOPICAL for the Prevention of Diabetic Foot Infections

... can lead rapidly to the infection spreading, with the possibility of tissue necrosis, gangrene, osteomyelitis, and ultimately the prospect of a lower leg amputation. Currently there are no antibiotics on the market specifically indicated for the prevention of diabetic foot infections. There is also ...

Edwards Lifesciences Announces First Implants in U.S. Study of Minimally-Invasive Pulmonic Valve

... pericardial valve is compressed onto a balloon to the approximate diameter of a pencil, threaded through the patient's circulatory system from the leg using the RetroFlex transfemoral delivery system and deployed across the patient's pulmonary valve. The valve replacement is accomplished as a ...

Study Results of GAMMAGARD S/D and GAMMAGARD LIQUID in Patients with Mild-to-Moderate Alzheimer's Disease Announced

... and prolonged periods of immobilization. Various minor reactions, such as mild to moderate hypotension, headache, fatigue, chills, backache, leg cramps, lightheadedness, fever, urticaria, flushing, slight elevation of blood pressure, nausea and vomiting, may occasionally occur. For full ...

New Deep Vein Thrombosis (DVT) Registry Data Show Clot Quickly Removed, Blood Flow Restored in Large Patient Registry

... Sixty-eight percent of the patients' thrombi were in the iliac vein (large thigh vein), 19 percent in the smaller femoropoliteal veins (in the leg area), and 13 percent in the subclavian vein (arm and neck area). Thrombus is generally classified by how long it has been present in the body; ...

MacroChem Announces Presentation of Pexiganan Phase 3 Study Results for Topical Treatment of Diabetic Foot Infection

... (osteomyelitis) or progressive gangrene, and are the major immediate cause of lower limb amputation. Diabetes is now the top cause of non-traumatic leg amputations in the developed world. Furthermore, foot ulcers are now the most frequent cause of diabetes-related hospitalizations. Thus, diabetic ...
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