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AcelRx Announces Positive Phase 2 Results from a Study of ARX-01 Sufentanil NanoTabs in Treating Post-Operative Pain

... in patients undergoing elective unilateral knee replacement surgery. Additionally, an open-label ... PCA System in patients undergoing unilateral knee replacement surgery. AcelRx Chief Medical ... Ph.D., commented, "The Phase 2 results from both knee replacement and major abdominal surgery studies ...

Ferring Pharmaceuticals Unveils Six-Month Efficacy Data for EUFLEXXA(R) for the Treatment of Osteoarthritis Knee Pain

... was effective at decreasing the pain of knee osteoarthritis (OA) at 26 weeks. The study ... (VAS). The 586 patients with chronic idiopathic knee OA were randomized to treatment with either ... acid (HA) approved in the U.S. for treatment of knee pain due to osteoarthritis (OA). EUFLEXXA(R) is ...

March 2009 Mayo Clinic Health Letter Highlights Knee Repair Surgery, Anxiety Disorder and Preventing Blood Clots

... 9771. Active at 50? Still Prime for knee Repair Surgery A torn anterior cruciate ligament (ACL), a type of knee injury, doesn't have to permanently sideline ... a key ligament that stabilizes and supports the knee joint. It connects the thigh bone (femur) to the ...

Treating Knee Ligament Injuries

... is the most frequently injured ligament in the knee . It attaches to the femur (thigh bone) and the ... or meniscus (cartilage between the bones in the knee joint). Knowing whether other structures in the knee are involved is vital to treating these injuries. ...

Octogenarians: Not Too Old for Joint Replacement

... New study finds total knee replacement surgery can offer significant ... LAS VEGAS, Feb. 26 /PRNewswire-USNewswire/ -- knee replacement ( ... 80s can benefit both physically and socially from knee replacement surgery, also called ...

When to Have That Joint Replacement?

... poorer joint function before undergoing hip or knee replacement surgery, according to a new study ... joint function of more than 3,500 hip and knee replacement patients based on physical exams and ... components of the Harris Hip Score and the knee Society Score, which were used to quantify the ...

Orthopaedic Surgeon Shortage Predicted Due to Soaring Joint Replacement Procedures

... ), the number of patients requiring hip or knee replacement surgery is likely to soon outpace the ... ) and 72 percent of needed knee replacements ( ... an orthopaedic surgeon at OrthoCarolina Hip and knee Center in Charlotte. "This is life-changing ...

American Academy Of Orthopaedic Surgeons 2009 Annual Meeting 'Highlights and Hot Topics'

... to set expectations. Pro Athletes and knee Surgeries ( ... Football players who underwent knee repair surgery in college prior to joining the ... careers if they underwent a meniscectomy, or knee meniscus repair, instead of surgical ...

Kensey Nash Announces IDE Submission for Cartilage Repair Device

... year to repair damaged articular cartilage in the knee and a majority of these are repeat procedures, ... joint ultimately requiring partial or total knee replacement. The Company believes that an early ... and consequently reduce the number of radical knee joint replacement surgeries performed each year. ...

Cymbalta(R) Significantly Reduced Osteoarthritis Knee Pain in New Study

... "As our population ages, osteoarthritis of the knee is likely to become an increasing problem." ... and with no invasive therapy of the knee in the past three months, knee arthroscopy within ... the management of osteoarthritis pain of the knee and reflects Lilly's current beliefs. However, as ...

Anesiva Announces Adlea ACTIVE-1 Phase 3 Clinical Results, Ceasing of Zingo Commercial Operations and Restructuring

... to be confirmed in the upcoming ACTIVE-2 total knee arthroplasty study which uses the same four to 48 ... the results of the Adlea Phase 3 trial in total knee replacement surgery. "These are difficult but ... the results of the Adlea Phase 3 trial in total knee arthroplasty, and pursuing partnering ...

Study Shows EUFLEXXA(R) Patients Report Significant Improvements in Osteoarthritis of the Knee Pain over a Six Month Period

... saline (IA-saline) for the relief of pain in knee osteoarthritis (OA) at 26 weeks. The results of ... reaction to hyaluronate preparations or who have knee joint infections or skin diseases in the area of ... pain) (8.75%) and back pain (5%). Temporary knee pain and swelling may occur after injection with ...

NicOx Announces Second Naproxcinod Pivotal Phase 3 Study (302) Meets Efficacy Primary Endpoints and Supports Non-Detrimental Blood Pressure Effect

... completed 301 study in osteoarthritis of the knee and the ongoing 303 study in osteoarthritis ... in which 1020 patients with osteoarthritis of the knee were enrolled at around 150 clinical ... Patients had primary osteoarthritis of the knee of at least 3 months duration. The general safety ...

Interleukin Genetics to Present Important New Findings at 2008 World Congress on Osteoarthritis

... Variations Identify Predisposition to More Severe knee Osteoarthritis ... Genetics. The genetic test appears to identify knee OA patients who are likely to develop more severe ... strongly and significantly associated with severe knee OA, as measured on radiographs. In addition, ...

New Research Shows Physical Therapy as Effective as Arthroscopic Knee Surgery

... Journal of Medicine Study Questions Value of knee Surgery ALEXANDRIA, Va., Sept. 11 ... of arthroscopic surgery for osteoarthritis of the knee should encourage patients to consider physical ... of moderate to severe osteoarthritis of the knee as surgery. "This study offers hope and ...

Patients Taking Cymbalta(R) Reported Reduced Pain Severity of Osteoarthritis of the Knee in New Study

... that patients with osteoarthritis pain of the knee treated with 60 mg and 120 mg Cymbalta ... in pain associated with osteoarthritis of the knee according to the primary efficacy measure of mean ... increases with age.(2) Osteoarthritis of the knee is a common type of this disorder, impacting the ...

Anesiva Announces Pivotal Phase 3 Clinical Trial of Adlea(TM) for Reducing Post-Surgical Pain Following Total Knee Replacement

... candidate, in patients following total knee replacement surgery, is underway. In September ... surgical site in patients undergoing total knee replacement surgery. Having completed enrollment ... on the 15 mg and placebo groups. "Total knee replacement is a commonly performed orthopedic ...

Genzyme Announces Presentation of New Positive Data on Carticel(R)

... Carticel who experienced improvement in knee function at an early follow-up, sustained their ... of 3.4 points on the Modified Cincinnati knee Rating System). Patients were young (mean age of ... experienced significant improvement in their knee function (mean improvement of 4.3 in overall ...

Osteoarthritis: Which Treatments Work and Which Don't?

... society develops 25 treatment recommendations for knee and hip osteoarthritis ... released set of treatment recommendations for knee and hip osteoarthritis may help millions of ... recommendations for the worldwide treatment of knee and hip osteoarthritis. "What the committee did ...

Knee Pain? An Exclusive Study Engineers Cartilage to Match Patient's Own Tissue

... MINNEAPOLIS, Jan. 8 /PRNewswire/ -- Patients with knee cartilage injuries now have the opportunity to ... bones at a joint such as the knee; symptoms of knee cartilage defects include pain, swelling and catching. In the United States alone, knee pain ranks the second highest source of ...

Clinical Data Presented on OrthoGlide(R) Medial Knee Implant

... alternative to total knee replacement MINNEAPOLIS, Nov. 28 /PRNewswire/ ... today the availability of OrthoGlide Medial knee Implant initial clinical data. Data ... would have been candidates for an invasive Total knee Replacement (TKR) procedure." A summary of the ...

Cost-Effectiveness Study Supports Use of EUFLEXXA(TM) by Rheumatologists for Pain Relief in Patients with Knee Osteoarthritis

... in patients with osteoarthritis (OA) of the knee at the American College of Rheumatology's Annual ... treatment course of HA (EUFLEXXA(TM)) for knee OA, as compared with non-HA therapy, provides a ... About the Study The study of 160 patients with knee OA compared costs and the extension of ...

The OrthoGlide(TM) Medial Knee Implant Continues to be Accepted as an Alternative to Total Knee Replacement

... company's minimally invasive knee implant. MINNEAPOLIS, Nov. 6 /PRNewswire/-- ... announced today the OrthoGlide Medial knee Implant has been implanted in more than 300 ... a minimally invasive alternative to the current knee replacement options on the market continues to ...

Anesiva Defines Regulatory Pathway for Adlea with FDA

... -- one of which has already been planned in total knee replacement surgeries -- and the second trial ... instillation in bunionectomy and 15 mg in total knee arthroplasty) will be evaluated. Anesiva is ... 2 trial evaluating patients undergoing total knee and another trial in total hip replacement ...

Evidence of Benefit Lacking for Many Common Ways of Treating Osteoarthritis of the Knee

... because of their purported benefits to relieve knee pain caused by osteoarthritis and improve ... of benefit from arthroscopic surgery to clean the knee joint with or without removal of debris and loose ... that wears away the cartilage cushioning the knee joint, causing pain and reducing ...

Anesiva Initiates New Phase 2 Trial of Adlea(TM) for Pain Relief Following Knee Replacement Surgery

... post-operative pain in patients undergoing total knee replacement surgery, also called total knee arthroplasty (TKA). Adlea is a long-acting, ... chief executive officer of Anesiva. "In total knee replacement surgery, up to 80 percent of these ...

Risks of Delaying ACL Reconstruction in Young Athletes May Be Too High, Study Shows

... reconstruction of a torn ACL must be balanced against the risk of further knee damage by delaying treatment until closer to skeletal maturity. Our study ... increase in patellotrochlear injuries. Issues with instability in the knee were also increased significantly. Our results highlight and help quantify ...

AcelRx Initiates a Phase 2 Study to Evaluate Functionality of Its ARX-01 Sufentanil NanoTab PCA System

... for post-operative pain management in patients undergoing unilateral knee replacement surgery. AcelRx Chief Executive Officer, Thomas Schreck, ... 2 studies evaluating the efficacy and safety of Sufentanil NanoTabs in knee replacement and major abdominal surgery patients. Now with this third ...

Oakwood Surgeons Perform World's First 3D Surgery Without Special Glasses

... Gold Seal of Approval from The Joint Commission for its hip and knee replacement program which includes the latest in minimally invasive technology, and a 14 bed sub-acute specialized unit for hip and knee replacement patients. To learn more about OHH please visit ...

Beating Blood Clots after Joint Replacement

... LAS VEGAS, Feb. 26 /PRNewswire-USNewswire/ -- As the number of hip and knee replacements skyrocket into the coming years, patients and orthopaedic ... available." More than 700,000 primary total hip and knee replacements are performed each year in the United States, and that number ...

Anesiva Announces FDA Approval of Supplemental New Drug Application to Expand Zingo(TM) Indication

... of reduced post-surgical pain versus placebo (p=0.03) following total knee arthroplasty (TKA, or total knee replacement surgery) at four to 48 hours after surgery. The trial also met ...

Research Highlights New Approaches to Prevent Blood Clots in Several High-Risk Patient Populations Including Largest Study Ever to Examine Use of Blood-Thinning Medication in Patients With Cancer

... Enoxaparin Every 12 Hours for Thro m boprophylaxis Af t er Total knee Replace m ent: RECOR D 4 [Abstract #35] Alexander G.G. ... enoxaparin, for the prevention of venous thromboembolism following total knee replacement surgery without significantly increasing the risk of bleeding. ...

Positive Phase II Study of Pacira's EXPAREL(TM) (DepoBupivacaine) in Total Knee Arthroplasty Presented at International College of Surgeons World Congress

... of EXPAREL(TM) (DepoBupivacaine) in patients who underwent total knee arthroplasty, or TKA, showed that the novel, sustained-release analgesic ... Center for Health Statistics. It is expected that the number of total knee replacement procedures will increase as our population continues to age. ...

Nuvo Research presents positive Phase III study results for Pennsaid at leading rheumatology conference

... is efficacious for the relief of symptoms in patients with symptomatic knee osteoarthritis," said Dr. Marc C. Hochberg, Head, Division of Rheumatology ... (arm 2) indicating that DMSO alone is ineffective against the symptoms of knee osteoarthritis (p greater than 0.05). There was no difference between ...

Omeros Announces Publication of Clinical Results for OMS103HP in Arthroscopy: The Journal of Arthroscopic and Related Surgery

... assessed over the 30-day postoperative period included measurements of knee function and motion, leg muscle strength, pain and return to work. Results of the study demonstrated a statistically significant improvement in knee function, range of motion, quadriceps and hamstring muscle strength, pain ...

Orthokine Treatment is Effective for Knee Arthritis, Even After Two Years

... August 5 /PRNewswire/ -- The results of a two-year representative study of knee osteoarthritis, published in the internationally renowned journal ... determine which one produces the best long-term results for treatment of knee osteoarthritis. A total of 310 patients received a series of injections ...

NicOx Completes Patient Enrollment in Third Naproxcinod Pivotal Phase 3 Study

... obtained in the 301 phase 3 study, in patients with osteoarthritis of the knee (see press release of October 27, 2006). These data demonstrated superior ... studies have produced a lower rate of positive efficacy results than knee studies. Nevertheless, we believe the stringent criteria applied to the ...

New Study Suggests Tapentadol IR for Acute Pain Is Associated With Improved Gastrointestinal Tolerability Compared to Oxycodone IR

... this study, patients with low back pain or pain from osteoarthritis of the knee or hip were treated with a flexible dose of 50 mg or 100 mg of tapentadol ... of 878 patients with low back pain or pain from osteoarthritis of the knee or hip studied the tolerability of long-term exposure (90-days) to ...

Financial Results for Full Year 2007: NicOx Significantly Advances Clinical Programs

... -- The 301 study was conducted in patients with osteoarthritis of the knee and has provided successful efficacy and blood pressure results which ... -- The 302 study started enrolling patients with osteoarthritis of the knee in the U.S. in April 2007 and the enrollment of 1020 patients was ...

NicOx Completes Enrollment in Second Pivotal Phase 3 Study for Naproxcinod and Provides Development Update

... and safety trial in which 1020 patients with osteoarthritis of the knee have been enrolled at 150 clinical sites throughout the United States. ... of the trial (39 weeks). Patients have primary osteoarthritis of the knee of at least 3 months duration. The trial has recruited both hypertensive ...
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