Kidney in Medical Technology

Amicus Therapeutics Commences Phase 3 Trial Evaluating Amigal(TM) for the Treatment of Fabry Disease

... primary endpoint of the change in the amount of kidney interstitial capillary GL-3, the substrate that ... endpoint will be the change in the amount of kidney interstitial capillary GL-3 as measured in kidney biopsies using histology. Secondary endpoints ...

Afinitor(R) Phase II Data Show Positive Results for Patients With Multiple Types of Lymphoma, Leading to Phase III Trial

... (5 mg and 10 mg tablets) to treat advanced kidney cancer after failure of treatment with sunitinib ... agencies globally for the treatment of advanced kidney cancer. Afinitor is being studied in multiple ... the prevention of organ rejection in heart and kidney transplant recipients. Certican was first ...

WORLD'S First Robotic Assisted Kidney Transplant Performed at Saint Barnabas Medical Center

... surgeon, Stuart R. Geffner, M.D., Director of kidney and Pancreas Transplant Surgery, Saint Barnabas ... Surgical System to successfully implant a kidney into a living recipient. This procedure revolutionizes kidney transplant surgery, taking an open procedure to ...

IMPACT Study Showed Longer Valcyte(R) (valganciclovir hydrochloride tablets) Treatment Demonstrated Better Protection Against Cytomegalovirus (CMV) Disease One Year Post-Transplant

... the incidence of CMV disease by 56% in high-risk kidney transplant patients within the first year ... Dr. Robert Gaston, Medical Director for kidney and Pancreas Transplantation and Professor of ... study for the prevention of CMV disease in kidney allograft recipients was a global, multi-center ...

Agennix Receives Fast Track Designation From FDA for Talactoferrin in Combination With Sunitinib for Renal Cell Carcinoma

... (RCC) RCC is the most common type of kidney cancer, accounting for approximately 90 percent of kidney tumors. According to the American Cancer Society, there are approximately 49,000 new cases of kidney cancer diagnosed each year in the United States. ...

Ongoing Landmark ROADMAP Study Demonstrates Significant Improvement in Blood Pressure Control at One Year, According to Blinded Results

... Olmesartan Medoxomil Prevents Onset of Early kidney Disease in Type 2 Diabetes Patients SAN ... (T2DM). Microalbuminuria is an early sign of kidney disease, as well as an important risk factor of ... Diabetes is among the leading causes of kidney failure.(4) High blood sugar levels and high ...

AUA Guideline: Full Kidney Removal Not Necessary for All Kidney Tumors

... kidney) is not the best treatment for most small kidney tumors because it puts patients at risk for chronic kidney disease and cardiovascular disease. ... are viable options for patients with early-stage kidney tumors, according to a new clinical guideline ...

Phase 3 Trial of Nexavar in Chemotherapy-Naive Patients with Advanced Melanoma Does Not Meet Primary Endpoint

... for the treatment of patients with advanced kidney cancer. Nexavar is also being evaluated by the ... breast cancer and as an adjuvant therapy for kidney and liver cancer. Important Safety ... hepatocellular carcinoma and advanced kidney cancer, hypertension may occur early in the ...

Osprey Pharmaceuticals U.S.A., Inc. Initiates Phase Ib Clinical Trial in IgA Nephropathy

... to Evaluate Safety of CCL2-LPM for Inflammatory kidney Disease SAN FRANCISCO, April 14 /PRNewswire/ ... the treatment of IgA nephropathy, an inflammatory kidney disease. Osprey Pharmaceuticals U.S.A. is ... axis plays a significant role in inflammatory kidney diseases such as IgA nephropathy and diabetic ...

Video: Afinitor(R) Approved in US as First Treatment for Patients With Advanced Kidney Cancer After Failure of Either Sunitinib or Sorafenib

... tumor growth or death in patients with advanced kidney cancer (4.9 vs. 1.9 months) and reduced the risk ... help us continue to offer patients with advanced kidney cancer new ways to battle their ... an unmet medical need for patients with advanced kidney cancer. Novartis has filed regulatory submissions ...

New Data for Abbott's TRILIPIX(R) (fenofibric acid) in Combination with Rosuvastatin Calcium Shows Improvement on Key Lipids for Cholesterol Management

... alone and TRILIPIX alone. No unexpected liver, kidney or muscle safety issues were identified in this ... by people with liver, gallbladder, or severe kidney disease, nursing mothers, or those allergic to ... away. Rarely, muscle-related problems can cause kidney damage and can be fatal. The risk of these side ...

DaVita Abstracts Accepted Into National Kidney Foundation's 2009 Spring Symposium

... Thirteen Abstracts Will Be Featured at Annual kidney Care Meeting EL SEGUNDO, Calif., March 25 /PRNewswire/ -- DaVita Inc., a leading provider of kidney care services for those diagnosed with chronic kidney failure and disease (CKD), in conjunction with ...

DaVita Abstracts Highlight Latest Research Developments at Annual Dialysis Conference

... Abstracts Reveal Ground-breaking Information on kidney Education and Modality Treatments EL ... -- DaVita Inc., a leading provider of kidney care services for those diagnosed with chronic kidney disease (CKD), in conjunction with DaVita ...

Quark Pharmaceuticals Presents at Asia TIDES Conference

... clinical studies for the prevention of acute kidney injury (AKI) and a Phase I/II clinical study for ... developed by Quark for the prevention of acute kidney injury (AKI) following major cardiac surgery and of delayed graft function in kidney transplantation. For the structure of these ...

Freezing Kidney Cancer: Hot Treatment Should Be New Gold Standard for Destroying Small Tumors

... March 9 /PRNewswire-USNewswire/ -- Freezing kidney tumors -- using a safe minimally invasive ... such an early stage is truly significant news for kidney cancer patients," he added. It's important ... options -- especially since the incidence of kidney cancer has been steadily increasing in this ...

For Old or Young Dialysis Patients, AV Fistulas Remain Pure Gold

... shows that for those individuals with chronic kidney disease, it doesn't matter if you're young or ... Lebanon, N.H. When kidneys fail -- called chronic kidney or end-stage renal disease -- treatment in the ... fistulas remain the gold standard of access for kidney dialysis patients. They last longer, need less ...

Quark Pharmaceuticals Announces Dosing of the First Patient in Phase I/II Clinical Trial for Systemically Delivered siRNA Drug Candidate for Delayed Graft Function

... kidney transplantation to be Quark's second indication ... (DGF) in patients undergoing deceased donor kidney transplantation. DGF represents Quark's second ... enrolling Phase I clinical trials in acute kidney injury (AKI). The multi-center, two-part ...

Synvista Therapeutics Announces Published Data Demonstrating Elevation of Carboxymethyl-Lysine (CML) Is Associated with Decline in Renal Function and Arterial Stiffness in Older Adults

... adults is independently associated with chronic kidney disease, and may be an independent predictor of ... adjusting for those that already had chronic kidney disease at the outset of the study. ... and damaging to organs such as the heart, kidney and skin among others. Collagen (a protein ...

Alexion Reports Positive Results from AEGIS Registration Study of Soliris in Japanese Patients With PNH

... Perhaps most noteworthy was the improvement in kidney function observed with eculizumab treatment. ... evaluate the effect of Soliris on Chronic kidney Disease (CKD), measured as an improvement or ... (3) Levey AS, Coresh J, Balk E, et al. National kidney Foundation Practice Guidelines for ...

First Clinical Experience With Soliris(R) in Treating Patients With Two Rare Complement-Mediated Diseases Presented at ASH Annual Meeting

... as reduced number of circulating platelets, and kidney damage. In two patients with aHUS, ... of blood vessels, often causing acute kidney injury and progressing to end-stage kidney disease. Those who survive aHUS often live with ...

Latest RAD001 Study Results Show Further Increase in Time Without Tumor Growth in Patients With Advanced Kidney Cancer

... once-daily oral mTOR therapy for advanced kidney cancer EAST HANOVER, N.J., Sept. 16 ... of RAD001 (everolimus) for patients with advanced kidney cancer who have failed standard therapies. ... extended period of time in patients with advanced kidney cancer that progressed despite treatment with ...

RAD001 Granted Priority Review in the US Based on Potential to Fill Unmet Medical Need in Patients With Advanced Kidney Cancer

... therapy targeting mTOR to treat advanced kidney cancer EAST HANOVER, N.J., Sept. 9 /PRNewswire/ ... significant benefit in patients with advanced kidney cancer after failure of standard treatment. ... of standard treatment in patients with advanced kidney cancer, RAD001 more than doubled time without ...

Cylex Announces Plan for Multi-Center Trial of ImmuKnow(R) Assay in South Korea

... collaborate on studies of immunosuppression in kidney transplant patients and role of cell-mediated ... the ages of 15 and 60 who undergo an initial kidney transplant and who are randomly assigned to ... monitor the immune status of patients following kidney transplantation. "The working hypothesis of ...

New Data Support Role for Monitoring of Cell-Mediated Immunity in Adult Patients Following Renal Transplantation

... in independent study of adult kidney transplant patients COLUMBIA, Md., Aug. 21 ... for organ rejection or infection subsequent to kidney transplantation. Pablo Sanchez-Velasco and his ... in 81 immunosuppressed adults who underwent kidney transplantation. The objective of their study was ...

DaVita Strives to Improve Quality of Life and Reduce Overall Costs of Kidney Care Through Community-Based Education

... -- DaVita Inc., a leading provider of kidney care services for those diagnosed with chronic ... out to more than 100,000 Americans through its kidney Education and You(R) program, which offers health ... seminars and useful tools to help prevent kidney disease brought on by risk factors like diabetes ...

Isis Highlights Robust Drug Portfolio for Diabetes and Obesity at ADA Conference

... in controlling glucose re-absorption in the kidney and the target of ISIS 388626. In addition, Isis ... formation. -- Lowered SGLT2 mRNA levels in the kidney by approximately 80% in all species tested, ... models, lowering levels of SGLT2 in the kidney by an antisense drug demonstrated very potent ...

The Largest Ever Study of Diabetes Shows Intensive Glucose Control Reduces Serious Complications

... intensive treatment reduces the risk of kidney disease by one-fifth. Presented today at the ... serious complications, particularly the risk of kidney disease, one of the most serious and disabling ... (by 10%), with a one-fifth reduction in kidney disease (21%) and 30% reduction in the ...

University of Miami Team Confirms Value of Monitoring Cell-Mediated Immunity Pre- and Post-Transplant in Management of Kidney Transplant Recipients

... with Cylex ImmuKnow(R) in the management of post kidney transplant recipients," will be presented on June ... clinical findings in patients undergoing kidney transplantation." Dr Carreno is the Assistant ... Transplant Laboratories. Patients undergoing kidney transplantation were ...

Cryoablation Is Focus of 17 Clinical Studies at American Urological Association Annual Meeting

... invasive treatment for prostate cancer and kidney cancer." Highlights from the 17 studies ... survival rates (more than five years) of kidney cancer patients showed that laparoscopic kidney cryoablation is an effective treatment in ...

RAD001 More Than Doubles Time Without Tumor Growth After Failure of Standard Treatment in Patients With Advanced Kidney Cancer

... new treatment option for patients with advanced kidney cancer who have failed standard therapies. The ... show clinical benefit in patients with advanced kidney cancer who have experienced treatment failure ... cell carcinoma (RCC) In the United States, kidney cancer accounts for approximately 3% of all adult ...

Pharmacopeia's First-in-Class Investigational Therapy PS433540 Achieves Statistically Significant Reductions in Blood Pressure in Hypertensive Patients

... of action may have a positive effect on diabetic kidney disease." Patients with diabetes are at an ... high blood pressure and diabetic kidney disease. Up to 73 percent of patients with ... of diabetic patients will progress to diabetic kidney disease,(6) a devastating disease that ...

Strength and Innovation of Novartis Oncology Products and Pipeline With Potential to Improve Patient Treatment Demonstrated by More Than 170 Abstracts at ASCO Annual Meeting

... new treatment option for patients with advanced kidney cancer who have failed standard therapies will be ... the prevention of organ rejection in heart and kidney transplant recipients. Certican was first ... other bisphosphonates have been known to cause kidney damage. Prior to each infusion, your doctor will ...

Data From Ortho Biotech-Sponsored Studies to be Presented at National Kidney Foundation 2008 Spring Clinical Meetings

... (DARB), evaluate medical costs related to chronic kidney disease (CKD) patients with hypertension ... Stimulating Agents in Patients with Chronic kidney Disease Patrick Lefebvre, M.A., Groupe ... Cost Considerations of Predialysis Chronic kidney Disease Patients Receiving Erythropoietic ...

St. Jude Study Offers New Hope for Children With Kidney Tumors Deemed Inoperable

... Surgeons were able to save part of each kidney in patients with bilateral Wilms tumor, ... preoperative imaging studies suggesting that kidney preservation might not be possible. "Many ... in an attempt to eradicate the cancer. If one kidney is removed and the cancer recurs in the other ...

BioNumerik Pharmaceuticals and ASKA Pharmaceutical Co. Announce Results from Phase III Clinical Trial of Tavocept(TM)

... reductions in chemotherapy-induced kidney damage and vomiting SAN ANTONIO and TOKYO, ... reduction in cisplatin-induced kidney damage (nephropathy) and a statistically ... to the study's size. Other side effects such as kidney damage and chemotherapy-induced vomiting were ...

Dynamis Therapeutics, Inc. Discovers RAGE Inhibitor

... to Develop Disease Treatments for Diabetic kidney Disease and Retinopathy, Each ... to the arsenal of drugs to treat diabetic kidney disease, retinopathy, microvascular disease, ... Therapeutics to develop a treatment for diabetic kidney disease and blindness. Diabetes and ...

Northwestern Memorial Transplant Program Initiates New Study

... Study seeks to wean certain kidney transplant recipients off anti-rejection drugs ... study that seeks to transplant stem cells from a kidney donor's bone marrow into the recipient, with the ... Sharon Flood of Pingree Grove, Ill. donated her kidney to her brother Steven Yelk of Gurnee, Ill., ...

Genzyme Corporation Selects Diplomat Specialty Pharmacy for 2008 Renagel Medicare Part D Assistance Program

... dedicated to products and services focused in kidney disease, rare inherited disorders, orthopedics, ... of serum phosphorus in patients with Chronic kidney Disease (CKD) on dialysis. The Renagel Part ... and commitment to patients with Chronic kidney Disease will help support Genzyme's premier ...

Kibow Biotech Obtains Australian, Chinese and Indian Patents Protecting the Composition and Basic Technology Behind Its Oral Probiotic Formulation for Chronic Kidney Failure

... "Compositions and Methods for Augmenting kidney Function," under national review in all of ... immense potential to our company products for kidney failure applications worldwide." About Kibow ... Biotics in slowing the progression of chronic kidney failure or helping patients feel better. Kibow is ...

Long-Term Soliris(R) Therapy Improved or Stabilized Kidney Function in Patients With PNH

... with PNH, hemolysis can cause thromboses, kidney disease, liver dysfunction, disabling fatigue, ... and anemia.(1-3) Impaired kidney function is common among patients with PNH, (4-8) ... of death in 8 to 18 percent of PNH patients. (9) kidney damage in PNH patients is likely due to ...