Isolated in Medical Technology

Study Data Show Asacol(R) (Mesalamine) is Effective in Treating All Extents of Ulcerative Colitis Including Isolated Proctitis

... all extents of ulcerative colitis (UC), including isolated proctitis. The results showed that patients with isolated proctitis who took Asacol, dosed at 2.4 g/day for ... g/day to treat active UC flares in patients with isolated proctitis. This analysis included data from the ...

Landmark Study in The New England Journal of Medicine Shows HPV Testing Significantly Reduces Deaths from Cervical Cancer, Compared to other Methods Including Pap

... of hours -- a critical characteristic for women traveling to clinics from isolated villages and for those women who may need to be treated the same day. ... samples such as blood or tissue. Assay technologies are used to make such isolated biomolecules visible. QIAGEN has developed and markets more than 500 ...

New Analysis Shows Troubling Trend in Triglyceride Levels May Be Linked to Rising Rates of Obesity

... emphasis has been placed on controlling triglycerides. The rising rates of isolated high triglycerides seen over the last three decades underscore the need ... in 1976 to 33.7 percent in 2006, while the percentage of Americans with isolated high triglycerides also doubled from 2.4 to 5.5 percent. The study also ...

Pivotal Phase III Data Confirm the Efficacy and Safety of Arpida's Intravenous Iclaprim in Treating Patients With Complicated Skin and Skin Structure Infections

... patients in the ITT population who had an infecting Gram-positive pathogen isolated at baseline; -- The PP population excludes all patients with any ... groups with Staphylococcus aureus (S. aureus) as the predominant pathogen isolated at baseline (76.5 percent for iclaprim and 81.1 percent for linezolid), of ...

St. Jude Study Finds Treatment With New Drug Might Make Tumor Cells More Sensitive to Therapy

... the molecule to enhance its potency and specificity and move studies from isolated cells to mouse models. "Results of those mouse model studies would help ... with cancer," Kastan said. The St. Jude researchers demonstrated in isolated cells that irradiation activated ATM, which in turn triggered the normal ...

Delcath Updates Phase III Patient Enrollment as Pivotal Trial Accelerates, Durable Tumor Responses In Phase II Study Also Cited

... with metastatic melanoma in the liver who had previously received surgical isolated regional therapy and are therefore ineligible for admission to the pivotal ... stage company testing its percutaneous perfusion technology for the isolated delivery of high doses of therapeutic and chemotherapeutic agents. The ...

New Data Shows Ranexa(R) Increases Glucose-Stimulated Insulin Secretion

... increased glucose-stimulated insulin secretion (GSIS) in pancreatic islets isolated from animals and humans. The Company believes that the increase in GSIS ... today showed that ranolazine increased GSIS in a dose-dependent manner in isolated islets. Acute administration of ranolazine to animals also significantly ...

New Data From Large Safety Analysis of MYCAMINE Shows Favorable Clinical Safety Profile

... in patients with hypersensitivity to any component of this product. isolated cases of serious hypersensitivity (anaphylaxis and anaphylactoid) reactions (including shock) have been reported in patients receiving MYCAMINE. isolated cases of clinically significant hepatic dysfunction, hepatitis, worsening ...

Cryo-Cell Announces C'elle(SM) Research and Development Collaboration with Cryopraxis Cryobiology Ltd.

... for female stress urinary incontinence, a condition primarily caused by a deficiency in the muscles that affect urine flow. Since stem cells isolated from menstrual fluid have the ability to contract, research will determine whether injecting the cells into the urethra would restore the ...

First Potential Lupus-Specific Treatment in Sight

... the lupus patients who were treated with BENLYSTA had improvement in overall disease activity without clinically significant flare-ups in one or more isolated organs when compared to patients who received the placebo (inactive agent). The patients receiving BENLYSTA also were able to reduce their intake of ...

Alfacell Provides Shareholder Update

... ONCONASE is a first-in-class therapeutic product candidate based on Alfacell's proprietary ribonuclease (RNase) technology. A natural protein isolated from the leopard frog, ONCONASE has been shown in the laboratory and clinic to target cancer cells while sparing normal cells. ONCONASE triggers ...

CEL SCI Collaborators Demonstrate Novel L.E.A.P.S. Vaccines Immunize Mice Against Tuberculosis Antigens and Suggest Potential to Treat Swine and Other Influenzas

... production which is known to be protective with many viruses and pathogens. "It is very exciting to see the effect of L.E.A.P.S. vaccines on isolated human immature dendritic cells using a simple molecule, in two different instances," said Dr. Zimmerman. "I am hopeful that other L.E.A.P.S. ...

WORLD'S First Robotic Assisted Kidney Transplant Performed at Saint Barnabas Medical Center

... on the youngest pediatric patient in the state, performing New Jersey's first laparoscopic kidney donation surgery, and performing the state's first isolated pancreas transplant. He operates at both Saint Barnabas Medical Center and Newark Beth Israel Medical Center. Dr. Geffner received his ...

Heart Disease Treatment Breakthrough

... to significantly reduce the build up of plaque in the arteries that can lead to heart attacks and stroke. Lycopene is the potent antioxidant isolated for its health-promoting properties from the Mediterranean diet ( http://www.ateronon.com/ ). Until now, scientists have been unable to find a ...

In Rare Disorder, a Familiar Protein Disrupts Gene Function

... childhood; now most children with the condition live into adulthood. CdLS has a wide range of severity, with the mildest form manifesting as apparent isolated mental retardation and/or autism. Krantz and colleagues investigated cohesin, a protein complex consisting of at least four proteins that form a ...

Siemens Corporate Research Develops RAPID2 System for Fast Discovery of Discriminative Pathogen Signatures

... SCR used its new system recently to quickly discover a DNA barcode for detecting the H1N1 Flu after they received the genomic sequences of the virus isolated from infected patients from the National Institute of Health (NIH). In addition to applications related to healthcare-associated infections ...

No Causality Found Between Black Cohosh and Liver Problems

... irritability and mood swings. While extensive research has been published on this botanical, the question of liver safety has arisen in a few isolated cases. Now, with the recent publication of Rolf Teschke, MD's re-evaluation of the four remaining cases held in question by the European Medicines ...

Two-Year Phase III Data Presented at AAN 61st Annual Meeting Show Positive Outcome of Cladribine Tablets in Patients With Multiple Sclerosis

... at week 14 of gestation in a cladribine-treated patient who became pregnant 6 months after completion of the study. Observed malignancies were isolated cases across different organ systems. The current ongoing clinical studies with Cladribine Tablets will provide data on a larger patient population ...

Affitech-Discovered Anti-PS Antibodies in Development by Peregrine Pharmaceuticals Show Excellent Functionality in Preclinical Studies

... the immune system. Additionally, PGN635 demonstrated encouraging signs of efficacy in a preclinical model of prostate cancer. Both antibodies were isolated using Affitech's unique MBAS (Molecule Based Antibody Screening) method for selection and improvement of fully human antibodies from large libraries. ...

Surveyed Neurologists Anticipate That Less Than 30 Percent of Their Use of Emerging Oral Agents in Multiple Sclerosis Will be in the First Line

... patients (the dominant multiple sclerosis subtype), they are less likely to prescribe disease-modifying therapies to patients with clinically isolated syndrome (early-stage multiple sclerosis). This is despite clinical studies indicating that early initiation of disease-modifying therapies can ...

Neuralstem's Human Stem Cells Integrate into Nervous System of Rats with Animal Model of ALS

... neurological degenerations." In a study conducted at Johns Hopkins Medical Institutions, laboratory-grown human neural stem cells (hNSCs) isolated from a fetal spinal cord region were grafted into the spinal cord of rats with a genetic mutation (SOD-1 G93A) that gives them a disease like a ...

Treating Knee Ligament Injuries

... Other nonsurgical treatments, such as gene therapy, growth factors, and small intestine submucosa, which is a naturally derived biomaterial isolated from the small intestine of pigs. All are currently in their early stages of use, but may hold some promise. Surgical treatment ...

Orthopaedic Injury: High Risk to Pregnant Women

... orthopaedic trauma often results from high-energy impact, such as car accidents, which may cause underlying damage to the placenta. "Even an isolated fracture can be the result of a high-energy event, and the impact can have a significant influence over fetal outcome," she noted. Dr. Cannada ...

Aching Back? Cholesterol Medication Might Help

... substance in the middle of the spinal disc.) The patients, ages 23 to 29, were undergoing surgery for herniated lumbar discs. Researchers then isolated the nucleus pulposus cells and eventually added Lovastatin, hoping to optimize the properties of the regenerative tissues. They hoped to maximize the ...

Blue Light Destroys Antibiotic-Resistant Staph Infection - Results Reported in Photomedicine and Laser Surgery Journal

... health threat. At present, fewer than 5% of staphylococcal strains are susceptible to penicillin, while approximately 40%-50% of Staph aureus isolated have developed resistance to newer semisynthetic antibiotics such as methicillin as well. Chukuka S. Enwemeka, Deborah Williams, Sombiri K. ...

Chemoembolization Improving as Liver Cancer Treatment

... beyond just palliation," said Glenn Stambo, M.D., vascular and interventional radiologist at St. Joseph's Hospital and Medical Center. "The more isolated the tumor and its blood vessel feeders, the better the chance for a complete cure." Improvements in Chemoembolization A multicenter Italian ...

Molecular Marker Identifies Normal Stem Cells as Intestinal Tumor Source

... models," Gilbertson said. "The tumorous tissue ultimately replaced the entire normal intestine. In terms of clinical importance, now that we have isolated both the normal, parental stem cells and the cancer stem cells, we can begin screening compounds that will affect the malignant stem cell but not the ...

Rib-X Pharmaceuticals Reports Positive Top-Line Results from Phase 2 Study of Delafloxacin

... complicated skin and skin structure infections (cSSSI). Additionally, when evaluated in vitro against the Gram-positive and Gram-negative organisms isolated from patients within this trial, delafloxacin was shown to be the more active compound overall, including its activity against Staphylococcus aureus ...

Alfacell Provides ONCONASE(R) NDA Submission Update

... ONCONASE is a first-in-class therapeutic product candidate based on Alfacell's proprietary ribonuclease (RNase) technology. A natural protein isolated from the leopard frog, ONCONASE has been shown in the laboratory and clinic to target cancer cells while sparing normal cells. ONCONASE triggers ...

Reprogrammable Cell Type Depends on a Single Gene to Keep Its Identity

... entered the reprogrammed mutant lymphatic vessels. Finally, the researchers used a trick that enabled them to block the ability of isolated cultured LECs to produce the Prox1 proteins to further demonstrate that Prox1 activity is required by LECs to maintain their identity. ...

Trellis(R) Peripheral Infusion System Removes Blood Clots in Largest Reported Prospective Endovascular DVT (Deep Vein Thrombosis) Patient Series

... Bacchus Vascular, Inc. (Santa Clara, CA) successfully breaks up the blood clot in most patients in about 20 minutes. This technique, called isolated pharmacomechanical thrombolysis, restores blood flow more quickly and safely than current catheter-directed thrombolysis (CDT) techniques. It ...

American Heart Association Journal Report: Surgical Residents Perform Heart Surgery as Effectively as Staff Surgeons

... underwent elective surgery, while about 15 percent underwent urgent or emergency surgery. Of the procedures the majority of the patients received isolated CABG. Resident cases: Staff cases: CABG 79.2 percent CABG 87 percent AVR 11.2 percent AVR 6.6 percent Combined 9.6 ...

Bioheart Reports Promising Results From Preclinical Study of Adipose-Derived Acute Cell Therapy

... patients soon after they have a heart attack." "The results of these Bioheart preclinical studies affirm our belief that the adipose-derived cells isolated from adipose tissue by the TGI System have the potential to assist in the treatment of a variety of medical conditions, including heart attacks," ...

Merck Serono Announces Initiation of the ORACLE MS Trial to Evaluate Cladribine Tablets in Patients at Risk of Developing Multiple Sclerosis

... placebo-controlled, international trial. It will involve more than 600 patients considered at risk of developing MS due to a recently experienced isolated demyelinating event (e.g. optic neuritis, myelopathy or brainstem syndrome) and having MRI brain scans consistent with early signs of MS. Study ...

Merck Serono Completes Enrollment in the REFLEX Trial of Rebif(R) in Patients at Risk of Developing Multiple Sclerosis

... believe the REFLEX study will provide valuable insights." A total of 517 patients considered at risk of developing MS due to a recently experienced isolated demyelinating event (e.g. optic neuritis, myelopathy or brainstem syndrome) and having magnetic resonance imaging (MRI) brain scans consistent with ...

Quigley Anti-Viral Compound QR448(a) Successfully Prevents Transmission of Infectious Bronchitis in Chickens

... birds from each colony were identified and infected with a full dose of the commercially available Arkansas type IBV vaccine virus and isolated for 2 hours. Due to safety, exposure and handling concerns of IBV in a large scale experiment, Arkansas type vaccine virus was recognized ...

Bionovo Reports on Metabolic Studies Related to Its Menopausal Hot Flash Drug Candidate

... and Experimental Therapeutics, Drug Metabolism and Disposition, entitled "Oxidative In Vitro Metabolism of Liquiritigenin, a Bioactive Compound isolated from the Chinese Herbal Selective Estrogen Beta-Receptor Agonist MF101." Liquiritigenin is one of the active compounds of MF101, Bionovo's ...

Catheter Ablation System for Atrial Fibrillation Shows Reduced Procedure Time, Remarkable Safety Profile and Excellent Outcomes in Two Clinical Studies

... Vein Ablation Catheter (PVAC(TM)) and GENius(TM) Multi-Channel Radiofrequency (RF) energy generator from Ablation Frontiers, 100% of the veins were isolated in 97 minutes (+/- 32 minutes) with just 20 minutes (+/- 9 minutes) of fluoroscopy. No complications were observed and 82% of the patients ...

Intercell Announces Initiation of Further Phase II Clinical Trial of V710 an Investigational Vaccine to Prevent S. aureus Infection

... heart and other inner organs are leading to serious health complications, death and economic burden. Today, approximately 50% of S. aureus strains isolated in hospitals worldwide are resistant to multiple antibiotics, rendering staphylococcal disease management increasingly difficult and challenging. ...

Want a Reason to Love Your Lower Belly Fat? It's Rich in Stem Cells

... trials in this country." In the study, 23 female patients having liposuction in at least four different body areas agreed to have their fat isolated for adult stem cells and analyzed to determine stem cell concentrations. The body areas that were liposuctioned were: lower abdomen, upper abdomen, ...