intestine

New Advances in Gastric Diagnostics: Smaller is Better

...n the capsule has been propelled through the small intestine system by normal peristalsis, the recorder is removed and the digital data downloaded into a computer for viewing. The Given capsulized system can provide images for the entire GI tract. It shows promise in diagnosing small bowel diseases including ...

Appendicitis: Evolving Tools to Diagnose a Classic Disease

...ndition occurs when the appendix, a blind pouch of intestine at the proximal colon, becomes obstructed by mucus, stool, or lymphatic tissue. Infection ensues, which can rapidly evolve to perforation and sepsis. The risk of these complications, already elevated for children and those over 50, rises as appende...

Non-Invasive Diagnostic Tests for Celiac Disease

...is an autoimmune inflammatory disease of the small intestine that is triggered in genetically susceptible persons by the ingestion of the gluten-containing grains wheat, rye, barley, and possibly oats. The condition is thought to result from the activation of both a T-cell and B-cell immune response, leading t...

Chi-Med Announces Positive Phase II Proof-of-Concept Data for HMPL-004 in Ulcerative Colitis

...red. Ulcerative Colitis generally affects thelarge intestine and Crohn’s Disease generally affects thesmall intestine. Ulcerative Colitis is the inflammation of the gut,which results in extensive ulceration of its inner surface withconsequential pain, loss of function and blood loss. Thedisease can requ...

An Investigational Study Released at ADA Showed that Initial Combination Therapy with Januvia (sitagliptin) and Metformin Led to Improvement in Markers of Beta Cell Function in Patients with Type 2 Diabetes

...sulinotropic polypeptide (GIP), arereleased by the intestine throughout the day, and levels are increasedin response to a meal. These hormones are rapidly inactivated by theenzyme, DPP-4. The incretins are part of an endogenous system involvedin the physiologic regulation of glucose homeostasis. When bloodgluc...

Late Breaking Data Released at ADA Showed that the Investigational Use of Januvia and Metformin as Initial Combination Therapy Provided Significant Glucose Lowering Efficacy over 54 Weeks in Patients with Type 2 Diabetes

...sulinotropic polypeptide (GIP), arereleased by the intestine throughout the day, and levels are increasedin response to a meal. These hormones are rapidly inactivated by theenzyme, DPP-4. The incretins are part of an endogenous system involvedin the physiologic regulation of glucose homeostasis. When bloodgluc...

Mymetics' HIV Vaccine Demonstrates First-Ever Production of Neutralizing IgA Antibodies in Non-Human Primate Model

... translocation at the genito-reproductive and intestine tracts and subsequent infection of target cells underlying the mucosal tissues, thereby preventing HIV entry and spreading in the body. 2- Focusing the immune response against conserved regions on gp41 that may induce protective a...

ChemoCentryx Presents Positive Phase 2 Clinical Data for Traficet-EN in Crohn's Disease at the Digestive Disease Week 2007 Conference

.... The trafficking of T cells tothe small and large intestine causes persistent inflammation thatmay result in Crohn's disease or ulcerative colitis -- the twoprincipal forms of IBD. In preclinical studies, the compound workedboth therapeutically and prophylactically in Crohn's disease.ChemoCentryx has complete...

UCB Presents Long-Term CImzia Data in Crohn's Disease

...l (GI) tract, most commonly at the end of thesmall intestine (the ileum) and in the large intestine (the colon).People with Crohn's disease may suffer all of their lives,experiencing an ongoing cycle ...

FDA approves MyocondaR IND for MAP in Crohn's Disease

.... The disease most commonly affects the lowersmall intestine and the large intestine. Symptoms of Crohn'sDiseas...rrhoea, fever and weight loss.In severe cases, the intestine can become blocked or obstructed,requiring surgery. Young patients with Crohn's Disease may also su...

Ulcerative Colitis (UC) Sufferers Find UC Quite Disruptive to Many Aspects of Daily Life

... autoimmune disease that causes inflammation inthe intestine and can lead to symptoms such as severe abdominalpain and cramping, uncontrollable bloody diarrhea several times aday, fatigue and weight loss. It is typically first diagnosed inpeople between the ages of 15 to 30 and is estimated to affectnearly 700...

Nuvelo Announces Publication of NU206 Study Results in Gastroenterology

...al lining andalleviating inflammation of the small intestine and colon. Inaddition, treatment with NU206 reduced the physiological symptomsof colitis, including weight loss, diarrhea, and rectalbleeding." The study investigated the efficacy of NU206 in reducing theseverity of colitis induced by dextran sulf...

Mymetics' HIV Vaccine Achieves Research Breakthrough, Eliciting Protective Antibody Response in Mucosal Tissues of Non-Human Primate Model

... translocation at the genito-reproductive and intestine tracts and subsequent infection of target cells underlying the mucosal tissues, thereby preventing HIV entry and spreading in the body. 2- Focusing the immune response against conserved regions on gp41 that may induce protective ...

Emisphere Technologies, Inc. Reports Clinical Data on Oral Delivery of GLP-1 and PYY

...rmonereleased from the distal portion of the small intestine thatinhibits proximal gastrointestinal events. Another important actionof GLP-1 is to induce satiety. About PYY Peptide YY 3-36 is produced by the gut and is released into thecirculation in response to food ingestion. Food intake is regulatedby the...

British Journal of Cancer Reports Preclinical Evidence of Positive Effect of Rice Bran on Intestinal Cancer

...r of precancerous adenomas in the stomachand large intestine of mice was observed. "The results show that the mice that received stabilized ricebran (30%) into their diets had a significant decrease in thenumber of intestinal adenomas compared to mice on the control diet.Rice bran also decreased intestinal he...