Inner in Medical Technology

Adult Circumcision Reduces Risk of HIV Transmission Without Reducing Sexual Pleasure

... by researchers in Australia, shows that the inner foreskin has the largest concentration of ... 10 circumcised men, researchers found that the inner foreskin has a significantly higher density of ... than other areas of the foreskin. By removing the inner foreskin, circumcision removes the skin surface ...

Quark Pharmaceuticals Signs Collaboration Agreement With University of Michigan for Development of Proprietary SiRNA Compounds for Noise-Induced Hearing Loss

... compounds to relevant cochlear cells in the inner ear. The efficacy of the selected siRNA compounds ... trauma, the residence time of siRNA in the inner ear cells, and the duration of the therapeutic ... of oxidative stress associated diseases of the inner ear, lungs and additional organs of the body. ...

Sound Pharmaceuticals Files Second IND with the FDA for the Prevention of Chemotherapy Induced Hearing Loss in Advanced Stage Cancer

... treatment reduces glutathione peroxidase (GPx) activity in the mammalian inner ear resulting in hearing loss, tinnitus, vertigo and dizziness. GPx is the dominant catalytic antioxidant enzyme within the inner ear, and a loss of its activity results in irreparable damage to hair ...

Want a Reason to Love Your Lower Belly Fat? It's Rich in Stem Cells

... July 23 /PRNewswire-USNewswire/ -- Fat removed from the lower abdomen and inner thigh through liposuction was found to be an excellent source of stem ... The body areas that were liposuctioned were: lower abdomen, upper abdomen, inner knee, inner thigh, flank and hips. The study results found a significant ...

Pulmo BioTech Inc. Completes Bio-Distribution Studies

... case of PulmoBind, the chosen molecule was designed to bond only to the inner walls of the vascular system of the lungs. Because the molecule (code ... delivered radionuclide tagged molecule which specifically bonds to the inner walls of the circulatory system in the lungs, and by the use of an ...

St. Jude Finds 'Dancing' Hair Cells Are Key to Humans' Acute Hearing

... A new study shows how sounds are amplified in the inner ear, a finding that could explain how hearing loss can result from genetic ... entering the cochlea are severely diminished as they pass through the inner ear fluid. In their studies, Zuo and his colleagues have sought to ...

Video: FDA Approves INVEGA(R) SUSTENNA(TM) for the Acute and Maintenance Treatment of Schizophrenia

... SUSTENNA(TM), common side effects in the treatment of schizophrenia were reactions at the injection site, sleepiness, dizziness, feeling of inner restlessness, and abnormal muscle movements, including tremor (shaking), shuffling, uncontrolled involuntary movements, and abnormal movements of the ...

Cystic Fibrosis - Liposomal Tobramycin Receives Second Orphan Drug Designation Within Weeks

... cell is triggered when the liposomes undergo a fusion process with the outer membrane of the bacterial cell wall. Tobramycin then penetrates into the inner cell compartment and triggers bacterial cell death. For further information, please contact: Dr. Helmut Brunar, Ph.D., CEO Axentis ...

Data Demonstrates Long-Term Reduction In Seizure Frequency With Novel Once Daily Anti-Epileptic Zebinix(R)

... MADRS score (p<0.0001) and individual domains of the MADRS scale including pessimistic thoughts, concentration difficulties, apparent sadness and inner tension(8). These data were presented at the 28th International Epilepsy Congress held in Budapest, 28 June 2009 - 2 July 2009, the 8th ...

King Pharmaceuticals Showcases Data From Pain Pipeline of Medicines Designed to Deter Common Methods of Non-Therapeutic Use

... EMBEDA(TM) Capsules (ALO-01), a novel opioid formulation, contain pellets of an extended-release formulation of morphine sulfate surrounding an inner core of naltrexone hydrochloride. EMBEDA(TM) is intended to treat moderate to severe chronic pain. This 12 month open-label safety study evaluated ...

Boston Scientific Launches Third-Generation Platinum Chromium Drug-Eluting Stent

... thin biodegradable abluminal polymer that delivers a very low dose of paclitaxel to the wall of the treated vessel, and no polymer or drug on the inner surface of the stent. Integrating the Element Stent architecture and a platinum chromium alloy with an optimized drug release, the "Labcoat Element" ...

Optimer Pharmaceuticals Presents Results From Fidaxomicin Phase 3 Study for the Treatment of Clostridium difficile Infection

... CDI has become a growing problem in hospitals, long-term care facilities and in the community. It is a serious illness caused by infection of the inner lining of the colon by C. difficile bacteria, which produce toxins that cause inflammation of the colon, severe diarrhea and, in the most serious ...

Cystic Fibrosis - Orphan Drug Designation for Innovative Treatment Against Lung Infections by Axentis Pharma AG

... between tobramycin and the microbial cell is triggered when the liposomes attach to the outer cell membrane. Tobramycin then leaches into the inner cell compartment, which leads to rapid cell death. About cystic fibrosis Cystic fibrosis is the most common life-threatening hereditary ...

Optigenex Inc. Signs New License and Distribution Agreement With Itochu Corporation of Japan

... normal physiological functions in adult life. Results of the study suggest that oral and topical AC-11(R) products, when combined, are an inner and outer beauty solution to help reverse the signs of premature aging. The French research, which was sponsored by Itochu, compliments earlier ...

Medgenics Announces Positive Data From Phase I/II Clinical Trial of EPODURE Treatment of Anemia in Chronic Kidney Disease

... mass-produced in animal cells." Medgenics' Biopump is a unique tissue-based platform technology that processes a toothpick sized sliver of the inner layer of the subject's skin and is intended to provide sustained-action protein therapy for the treatment of a range of chronic diseases, including ...

Pulmo BioTech Inc. Announces Dual Listing on Frankfurt Borse

... that market. About PulmoBind PulmoBind uses an intravenously delivered radionuclide tagged molecule which specifically bonds to the inner walls of the circulatory system in the lungs, and, by the use of an external Gamma Camera, allows an image of the integrity of the blood vessels ...

Late-Breaking Data Highlighting Research Advances in Several Blood Disorders to Be Presented At the American Society of Hematology Annual Meeting

... CA. Results from a study examining the ability of an investigational agent to improve endothelial dysfunction, a malfunction in the inner lining of blood vessels, in patients with sickle cell disease will be featured at a press conference on Saturday, December 6, at 9:30 a.m. "Abnormal ...

Study Published in Journal of Clinical Psychiatry Showed Once-Daily VYVANSE(R) (lisdexamfetamine dimesylate) Significantly Improved ADHD Symptoms in One of the Largest Controlled Stimulant Trials in Adults with ADHD

... "It is important for people to realize that in adults, the core symptoms of ADHD -- inattention, hyperactivity, and impulsivity -- may present as inner restlessness, a lack of focus and organization, poor time management, or an inability to finish tasks, which can impact adults' daily lives. In this ...

Bioheart Reports Promising Results From Preclinical Study of Adipose-Derived Acute Cell Therapy

... of circulating blood to the myocardium (heart). This results from the clogging of an artery, potentially due to a build-up of cholesterol in the inner wall of blood vessels that distribute blood to the heart muscle, or thrombosis (clot). This can lead to a part of the heart muscle becoming ...

Cystic Fibrosis Axentis Pharma Initiates Clinical Trial for Lung Infections

... between tobramycin and the microbial cell is triggered when the liposomes attach to the outer cell membrane. Tobramycin then leaches into the inner cell compartment, which leads to rapid cell death. For further information, please contact: Axentis Pharma AG, Brandschenkestrasse 60, ...

Intercell Announces Initiation of Further Phase II Clinical Trial of V710 an Investigational Vaccine to Prevent S. aureus Infection

... cause of hospital-acquired infections. In addition to bloodstream infections with a mortality rate of up to 35%, infections of bone, heart and other inner organs are leading to serious health complications, death and economic burden. Today, approximately 50% of S. aureus strains isolated in hospitals ...

Generex Biotechnology Corporation Initiation Coverage Review Issued By Scimitar Equity, LLC

... The Company's proprietary liquid formulations allow drugs typically administered by injection to be absorbed into the body by the lining of the inner mouth using the Company's proprietary RapidMist(TM) device. The Company's flagship product, oral insulin (Generex Oral-lyn(TM)), which is ...

Pulmo BioTech Announces Details of the Methodology for its Phase I Human Trials

... to dominate that market. About PulmoBind PulmoBind uses an intravenously delivered radionuclide tagged molecule which specifically bonds to the inner walls of the circulatory system in the lungs, and by the use of an external Gamma Camera allows an image of the integrity of the blood vessels ...

PulmoBioTech Announces Details of Its Regulatory Approval Experiments

... to dominate that market. About PulmoBind PulmoBind uses an intravenously delivered radionuclide tagged molecule which specifically bonds to the inner walls of the circulatory system in the lungs, and by the use of an external Gamma Camera allows an image of the integrity of the blood vessels ...

New Data Showed ACTOS(R) (pioglitazone HCl) Prevented Progression of Atherosclerotic Plaque Volume in Patients With Type 2 Diabetes

... was to compare the effects of ACTOS versus glimepiride, a sulfonylurea, on carotid intima-media thickness (CIMT), defined as the thickness of the inner lining of a patient's neck arteries. CIMT is an established surrogate marker of atherosclerosis. The CHICAGO analysis demonstrated a similar result ...

BioVascular Inc. Closes $10.87 Million Series C Financing

... of leech saliva (Hirudo medicinalis) and currently produced as a recombinant protein in yeast. The polypeptide is designed to be applied to the inner surface of the arterial wall during surgery. There, it coats exposed collagen fibrils and inhibits the binding of platelets to those fibrils. By ...

ActivBiotics Receives Orphan Drug Designation from the European Medicines Agency for Superoxide Dismutase Mimetic, M40403, in Oral Mucositis Indication

... at risk of developing oral mucositis. In addition to killing tumor cells, radiation therapy also adversely affects surrounding tissues including the inner lining (mucosa) of the mouth. The resulting "oral mucositis;" is the number one patient-reported debilitating side effect of cancer therapy. The ...

EntreMed Commences Phase 2 Study With MKC-1 in Ovarian/Endometrial Cancers

... with approved chemotherapeutic agents. Endometrial cancer, the most common cancer found in women's reproductive organs, starts in the inner lining of the uterus (endometrium). The American Cancer Society estimates that there will be approximately 39,000 new cases of cancer of the uterine ...

Nobel Laureate Dr. Gunter Blobel to Speak at Florida Atlantic University

... Howard Hughes Medical Institute. He will present a lecture entitled, "Nucleo-cytoplasmic Traffic," highlighting his groundbreaking research on the inner workings of the cell. Blobel has spent years investigating and learning how proteins are delivered to their proper location to perform their ...

Do-It-Yourself Cardiac Bypass Surgery: All You Need is Walking Shoes

... case of a heart attack. And exercise can boost these blood vessels. Exercise dramatically increases blood flow through the coronary arteries. The inner lining of the arteries responds to this "stress" much as it does to the stress of atherosclerosis, by stimulating collateral blood vessels to ...

Indevus Pharmaceuticals Reports Positive Results of Phase II Octreotide Implant Trial

... formulation of octreotide in a six-month implant utilizing the Company's patented Hydron technology. The implant is inserted subcutaneously in the inner aspect of the upper arm and is specifically designed to provide a continuous release of octreotide, a long-acting octapeptide that mimics the natural ...

Quark Pharmaceuticals, Inc. Announces First Systemic siRNA Dosing in Humans

... on novel targets and therapeutic concepts discovered using BiFAR(TM) and designed for the treatment of oxidative stress associated diseases of the inner ear, lungs and additional organs of the body. Quark is headquartered in Fremont, California and operates research and development facilities in ...

New Data from the Framingham Heart Study Supports PAT Technology to Diagnose Early Cardiovascular Disease

... device that reliably detects a pathology called endothelial dysfunction. The condition refers to an impairment of the endothelial layer, which is the inner tissue lining of the blood vessels and is emerging as a key precursor for the development of atherosclerosis -- a major component in cardiac disease, ...

Data Presented at the American Heart Association Scientific Sessions 2007 Demonstrated Increased HDL with ACTOS(R) (pioglitazone HCl) Slowed the Progression of Carotid Intima-Media Thickness in Patients with Type 2 Diabetes

... 4 through 7, 2007 in Orlando, Florida. Results revealed that reduced progression of carotid intima-media thickness (CIMT), the thickness of the inner lining of a patient's carotid, with ACTOS was associated with increased HDL cholesterol and decreased insulin levels when compared to glimepiride. An ...

Boston Scientific Carotid Artery Stenting Trials Produce Positive Three-Year Results

... a self-expanding stent with a braided, closed cell design. Closed-cell configurations are designed to increase lesion coverage and provide a smooth inner lumen to help facilitate delivery and retrieval of ancillary devices. The FilterWire EZ System -- an advanced technology designed for simplicity and ...

Studies Show Body Mass Index Has No Effect on Resolution and Healing of GERD Symptoms

... Poster Award. The other study examined GERD patients with erosive esophagitis, a condition in which stomach acid wears away, or erodes, the inner lining of the esophagus over time. Results of both studies showed despite whether a patient with GERD is considered obese or not, treatment should ...

Quark Pharmaceuticals Appoints New Chief Medical Officer

... on novel targets and therapeutic concepts discovered using BiFAR(TM) and designed for the treatment of oxidative stress associated diseases of the inner ear, lungs and additional organs of the body. Quark is headquartered in Fremont, California and operates research and development facilities in ...

Quark Pharmaceuticals Files Patent Application Covering Novel Chemical Modifications to its RNAi Molecules

... on novel targets and therapeutic concepts discovered using BiFAR(TM) and designed for the treatment of oxidative stress associated diseases of the inner ear, lungs and additional organs of the body. Quark is headquartered in Fremont, California and operates research and development facilities in ...

Quark Pharmaceuticals Extends Research Agreement with State University of New York for Proprietary siRNA Compounds for Acute Hearing Loss

... on novel targets and therapeutic concepts discovered using BiFAR(TM) and designed for the treatment of oxidative stress associated diseases of the inner ear, lungs and additional organs of the body. Quark is headquartered in Fremont, California and operates research and development facilities in ...

Quark Pharmaceuticals, Inc. Presented Positive Preclinical Results of Systemic RNAi Compound for Acute Renal Failure (ARF)

... on novel targets and therapeutic concepts discovered using BiFAR(TM) and designed for the treatment of oxidative stress associated diseases of the inner ear, lungs and additional organs of the body. Quark is headquartered in Fremont, California and operates research and development facilities in ...