Near-Patient Testing: The Advantages of C-Reactive Protein in Hematological Testing
... an acute phase plasma protein, is involved in the innate inflammatory response and is a well known marker of systemic inflammation. CRP is secreted rapidly, within a few hours of the immunological insult, upon activation by specific cytokines. CRP is, therefore, a particularly sensitive and interesting to...Biothera's Imprime PGG Enhanced Effectiveness of Avastin in Cancer Study
...biological response modifier that enhancesspecific innate immune cell responses. Biothera has completed twoP...focus is developingpharmaceuticals that engage the innate immune system to fightcancer. Other applications include hematopoiesis (production ofblood cells) an......litis and malaria. CEL-1000 appears to activate innate (very early stage) and Th1type (cellular) immune r...protection against infection in animal models. The innate immunesystem is generally accepted to be the first line of defenseagainst infectious agents. CEL-10......ephalitis and malaria.CEL-1000 appears to activate innate (very early stage) and Th1 type(cellular) immune r... protectionagainst infection in animal models. The innate immune system isgenerally accepted to be the first line of defense againstinfectious agents. CEL-10...New Report Illuminates Ampligen's Unique Mechanism of Action
...l for theactivities of dsRNAs for the induction of innate immunity. Unlikethe toxic Poly I:Poly C, Ampligen ...towards theactivation of TLR-3 in the induction of innate immuneresponses. The closely allied compound, Poly I : Poly C, has been used inclinical trials but ...The Sturdier Sex?: Study by Pittsburgh Scientists Finds Female Stem Cells Work Better
...e male cells (95). This difference may arise from innate sex-related differences inthe cells' stress responses, according to Dr. Deasy, an assistantprofessor in the Departments of Orthopaedic Surgery andBioengineering at the University of Pittsburgh School of Medicineand School of Engineering, respectively...... developing therapeutics that utilize thispowerful innate response without the threat of a cytokine stormtha...i-infective peptide that selectively modulates the innate immuneresponse" in Nature Biotechnology (April 2007, vol. 25 No. 4) andwill be accessible online on ......lture have revealed elevations in componentsof the innate immune system that are consistent with Toll-likeReceptor activation, a postulated mechanism by which vaccineadjuvants accomplish their immunosensitization. Additionally, theanti-anthrax activity reported by Homspera is similarly consistentwith activa......withpotential therapeutic benefit -- they regulate innate and adaptiveimmunity, reduce nonproductive inflammation and stimulate cellproliferation. The Company's lead product candidate, NEUMUNE(R)(HE2100), has shown significant effects in models of AcuteRadiation Syndrome (ARS), a life-threatening condition ...