Influenza in Medical Technology

Sanofi Pasteur Submits Supplemental Application for A(H1N1) Pandemic Vaccine to U.S. FDA

... a supplemental application for licensure of its influenza A(H1N1) 2009 monovalent vaccine. Responding to ... application requests the FDA's evaluation of the influenza A(H1N1) 2009 strain change, which is expected to ... officials in producing a vaccine against the influenza A(H1N1) 2009 virus ," said Wayne Pisano, ...

NOVAVAX Achieves Pandemic H1N1 Influenza Production Milestone

... (VLP) vaccine candidate against the H1N1 pandemic influenza virus under current good-manufacturing practices ... technology which is not dependent on growing influenza virus in eggs. Chicken eggs are used to produce almost all of the world's influenza vaccine supply. In addition, Novavax has ...

AlphaVax Announces Results from Initial Testing of Its H1N1 (Swine) Influenza Vaccine

... immunogenicity studies of its H1N1 (swine) influenza vaccine and will manufacture clinical trial ... provides several potential advantages over other influenza vaccine approaches in that vaccines can be ... vaccine will be based on two previous successful influenza vaccine trials run by AlphaVax, one carried out ...

BioCryst Pharmaceuticals Reports Positive Results of Shionogi & Co. Sponsored Phase 3 Studies of i.v. Peramivir for Influenza

... Osaka, Japan and conducted during the 2008-2009 influenza season. Shionogi and Green Cross Corporation, ... dosing over multiple days. The study enrolled 42 influenza patients at high-risk of serious complications ... are important, especially during the declared influenza pandemic, as they indicate the promise of ...

MJFF's Rapid Response Innovation Awards Hit Mid-2009 With Over $1 Million Funded in High-Risk/High-Reward Approaches to Parkinson's Disease

... a tenuous link between PD and certain strains of influenza virus; and a proof-of-principle approach to ... that the virulent H5N1 ("bird flu") strain of influenza virus can play a role in inducing parkinsonism. ... mostly based on cases from the Spanish influenza outbreak of 1918, documenting Parkinson's disease ...

Hand Washing with 4% CHG Antiseptic Kills Flu Viruses

... instructions. The strain tested was Swine Flu influenza A H1N1 A/Swine/Iowa/15/3. The time-kill ... comparator test product. "With any type of influenza outbreak, managing the spread of virus is the ... hands or other contact behaviors. With any influenza outbreak, good hand hygiene is extremely ...

Intercell AG Announces First Subject Enrolled in a Phase II Trial for the Further Development of Its Investigational Vaccine Enhancement Patch to Improve Pandemic Influenza Prevention in Collaboration With U.S. Department of Health and Human Services (HHS

... in combination with an injectable H5N1 pandemic influenza vaccine started today in the U.S. - The ... and improve protection against an H5N1 pandemic influenza outbreak with only a single dose vaccine ... VE Patch to improve prevention of H5N1 pandemic influenza with the start of a Phase II clinical trial. The ...

Novavax Completes Enrollment of Its Second Phase II Seasonal Influenza VLP Vaccine Clinical Trial

... its trivalent virus-like particle (VLP) seasonal influenza vaccine. This Phase IIa randomized, ... a VLP vaccine against the H3N2, H1N1, and B influenza strains that circulated in the 2008-2009 influenza season. This clinical trial represents another ...

Quest Diagnostics Introduces First Commercial Laboratory Test for Identifying the H1N1 Swine Flu Virus

... clinical specimens confirmed positive for influenza A H1N1 Swine-origin flu virus MADISON, ... chain reaction (PCR) test to aid in identifying influenza A H1N1 Swine-origin (H1N1) flu virus ("S-OIV" or ... known as the Swine Flu. The Focus Diagnostics influenza A H1N1 (Swine Flu) RNA Real-Time RT-PCR Test is ...

BioCryst Provides Peramivir Update and Reports First Quarter 2009 Financial Results

... peramivir through an EUA in the event of a severe influenza outbreak with significant hospitalizations. ... i.v. peramivir as a treatment option for an influenza emergency," said Jon P. Stonehouse, President and ... Peramivir Phase 2 Study Results for Seasonal influenza BioCryst also announced preliminary ...

New Study Shows Probiotic Strain Effective in Boosting Immune Response to Flu Virus

... immune marker, versus control upon exposure to influenza A in healthy adults who consumed a daily capsule ... of flu pandemics, many of which are variants of influenza A. (Logo ... in blood TNF-alpha levels upon exposure to influenza A in 10 healthy adults prior to and following a ...

American Lung Association Offers Simple Tips to Protect Public Health and Minimize H1N1 Flu (Swine Flu) and Seasonal Flu Transmission

... currently no vaccine for the H1N1 strain of the influenza virus, it is still important that people receive their annual influenza vaccination. Seasonal influenza and its complications are responsible for an ...

EPSScentral Responds to Pandemic Alert

... the face of WHO's phase 5 classification of the influenza A crisis. According to the WHO, phase 5 ... is ... to mitigating business disruption caused by influenza A, especially in these challenging economic ... and access to additional expert knowledge as the influenza A (aka H1N1, Swine Flu) or other pandemic ...

Smithfield Sends Update to Employees on Testing Process at Veracruz Joint Venture

... The media continues to cover the global A(H1N1) influenza outbreak on a minute-to-minute basis, and while ... bodies have confirmed that you cannot get A(H1N1) influenza from eating pork or pork products, and there is ... President Obama and others, that the A(H1N1) influenza virus is not transmitted by food and can only ...

Plasma Products Safe Despite Swine Influenza Outbreak, Assures International Biopharmaceutical Company Octapharma

... Plasma Derivatives The impending influenza pandemic will have implications for global ... have travelled to countries affected by the swine influenza outbreak or who have been in close contact with ... it inactive and unable to infect. All influenza viruses are lipid enveloped viruses and not very ...

USAID Provides $5M in Emergency Support as Swine Flu Spreads

... concern. On April 27, WHO raised the level of influenza pandemic alert to Phase 4, indicating an ... protective equipment from its avian and pandemic influenza stockpile to support ongoing response efforts by ... to support pandemic its Avian and Pandemic influenza prevention and preparedness activities across the ...

Progress Against Malaria and Other Infectious Diseases Among Highlights at Annual Vaccine Conference

... a bird-flu epidemic; and prevention of seasonal influenza among school-age children by holding in-school ... thousands of people." Improvements to Avian influenza Vaccine Researchers from sanofi pasteur ... made with the pandemic strain. Boosting influenza Vaccine Coverage among School-Age Children ...

Nobilon Advances First Vaccine Into Human Trials - Intranasal Influenza Vaccine Begins Phase I Clinical Development

... for SCH 900795, a new intranasal Live Attenuated influenza Vaccine (LAIV) for annual seasonal use. The ... vaccine is composed of the three attenuated influenza viruses recommended by the World Health ... device. The LAIV differs from most existing influenza vaccines, because it has been designed to offer ...

Children's Hospital Receives $6.7 Million Grant From Gates Foundation to Study Influenza Vaccine in Pregnant Women in Asia

... to help mothers protect their infants against influenza in this vulnerable time. Researchers led by ... by a Gates Foundation grant) showing that influenza vaccine not only prevents pregnant women from ... randomized trial in an urban setting, that the influenza vaccine protects both mothers and their ...

Data from Phase 2 Study of Peramivir in Patients Hospitalized with Influenza Presented at the XI International Symposium on Respiratory Viral Infections

... 2 study of peramivir in patients hospitalized for influenza was presented by the study's Principal ... options for the 200,000 patients hospitalized for influenza each year and we believe peramivir may be a ... knowledge of the clinical and virologic course of influenza in hospitalized patients who receive ...

Novavax Reports Positive Preclinical Results for a Novel, Broadly Cross-Protective H5N1 Pandemic Influenza Virus-like Particle (VLP) Vaccine Candidate

... for Development of the Next Generation of influenza Vaccines with Broad Protection Against Multiple ... results for a new broadly immunogenic pandemic influenza virus-like particle (VLP) vaccine candidate that ... important for inducing protection against influenza infection and severe disease. This ...

Novavax Presents Favorable Results from Phase I/IIa Pandemic Influenza Vaccine Program at World Health Organization Conference

... Organization Meeting on Evaluation of Pandemic influenza Prototype Vaccines in Clinical Trials, Novavax, ... Phase I/IIa human clinical trial of its pandemic influenza virus-like particle (VLP) vaccine candidate. The ... been shown to be important for protection against influenza disease. Novavax's VLP candidate is directed ...

USD 12.5 m Funding for the Development of Intercell's Vaccine Patch System for Pandemic Influenza From U.S. Department of Health and Human Services (HHS)

... funding of USD 12.5 m for Intercell's Pandemic influenza program. Intercell is developing a Pandemic influenza Vaccine Patch System that includes an ... in conjunction with an injected Pandemic influenza vaccine (manufactured by Solvay Biologicals, ...

Novavax Announces Top Line Results of Phase IIa Clinical Trial for Its Seasonal Influenza VLP (Trivalent) Vaccine Candidate

... follows positive results from its pandemic influenza vaccine Phase IIa trial in July 2008; plans to ... a Phase IIa human clinical trial of its seasonal influenza VLP (trivalent) vaccine candidate. The vaccine, ... to correlate with protection against seasonal influenza disease. The Phase IIa randomized, ...

Vical Pandemic Influenza Vaccines Achieve T-Cell Responses and Cross-Clade Reactivity in Humans

... Vaxfectin (R)-formulated H5N1 pandemic influenza DNA vaccines induced T-cell responses against a matching strain of influenza virus and demonstrated cross-clade antibody ... Vegas - December 9-11). H5N1 Pandemic influenza Vaccine Phase 1 Trial Update New data ...

Video: New Survey Finds Mothers See Influenza as a Serious Health Threat, but Often Don't Get Their Families Vaccinated

... American Lung Association's 2008 Faces of influenza survey underscores that mothers need to get ... percent of mothers in the United States consider influenza a severe and potentially life-threatening disease ... families are largely unaware they are at risk for influenza infection and to reinforce the need for greater ...

Video: Novartis Vaccines and PTA Battle Flu: Public Health Vaccination Initiative Urges Families 'Let's Fight Flu Together!'

... a national public health initiative for influenza vaccination for school-aged children, their ... on-site vaccinations provider, for a nationwide influenza vaccination campaign called "Let's Fight Flu ... During the 2008/2009 influenza season, "Let's Fight Flu Together!" vaccination ...

Vical Expands Applications of Vaxfectin(R) Adjuvant for Infectious Disease and Cancer Vaccines; 80% to 100% of High-Dose Responders in H5N1 Clinical Trials Still Responding at 6 Months

... agent with protein-based commercial seasonal influenza vaccine and with protein-based H5N1 pandemic influenza vaccine currently stockpiled by the U.S. ... that Vaxfectin(R)-formulated seasonal influenza vaccine generated broader, more balanced antibody ...

NOVAVAX Featured at Clinton Global Initiative 2008 Annual Meeting

... affordable methods of producing an H5N1 avian influenza vaccine and a seasonal influenza vaccine using the company's proprietary ... solutions for producing avian and seasonal influenza vaccines with portable equipment that can ...

Novavax Announces Favorable Results from Phase I/IIa Pandemic Influenza Vaccine Program

... Phase I/IIa human clinical trial of its pandemic influenza virus-like particle (VLP) vaccine candidate. The ... A/Indonesia/05/2005 avian influenza strain. Avian influenza emerged in humans in Indonesia in 2005 and ... to address an unmet need in pandemic influenza preparedness efforts being planned by health ...

Survey Shows Parents' Best Intentions Out of Step with Expert Recommendations in Protecting Kids from Flu

... (44 percent) say their child has ever received an influenza vaccine.(1) Furthermore, only about half (48 ... Practices (ACIP) expanded their annual influenza vaccination recommendations to include ... "the flu," is a contagious disease caused by the influenza virus.(3) The flu, much like the common cold, ...

Karolinska Institutet to Test Vical's Vaxfectin(R) Adjuvant With Preventive Vaccine against HIV Under Sponsorship of Swedish Institute for Infectious Disease Control

... Phase 1 trial of the company's H5N1 pandemic influenza DNA vaccines marked the first time ... testing with the company's H5N1 pandemic influenza DNA vaccines. Vaxfectin(R) has also demonstrated a dose-sparing effect with the commercial seasonal influenza and government-stockpiled H5N1 pandemic influenza ...

Karolinska Institute to Test Vical's Vaxfectin(R) Adjuvant with Preventive Vaccine against HIV Under Sponsorship of Swedish Institute for Infectious Disease Control

... Phase 1 trial of the company's H5N1 pandemic influenza DNA vaccines marked the first time ... testing with the company's H5N1 pandemic influenza DNA vaccines. Vaxfectin(R) has also demonstrated a dose-sparing effect with the commercial seasonal influenza and government-stockpiled H5N1 pandemic influenza ...

Inverness Medical Innovations Receives USDA Licensure of the BinaxNOW(R) Avian Influenza Virus Type A Antigen Test Kit

... market and distribute the BinaxNOW(R) Avian influenza Virus Type A Antigen Test Kit. Test results are ... Responding to a USDA-identified need for a rapid influenza test for veterinary use, Inverness sought and has ... test (ICT) that detects influenza A nucleoproteins in chicken, turkey and duck ...

Sanofi Pasteur Shipping First Doses of Influenza Vaccine for the 2008-2009 Season in the US

... began shipping influenza vaccine (Fluzone(R), influenza Virus Vaccine) in the United States for the ... planned to be completed in October. This year's influenza vaccine contains three new strains of ... virus. The three strains for the new influenza vaccine formulation were confirmed by the FDA's ...

BioCryst Reports Positive Preliminary Results of a Shionogi & Co., Ltd. Sponsored Phase II Study of I.V. Peramivir for the Treatment of Influenza in the Outpatient Setting

... a positive rapid antigen test indicating acute influenza illness. Subjects were randomized to receive ... may have as a potential treatment for influenza in this setting. With the advent of influenza virus resistant to currently ...

Vical Announces Breakthrough for Pandemic Influenza DNA Vaccines With Preliminary Human Data

... responses against H5N1 pandemic influenza in humans. DNA vaccines are fundamentally ... company's Vaxfectin(R)-formulated H5N1 pandemic influenza DNA vaccines demonstrated for the first time ... that an adjuvanted DNA vaccination against H5N1 influenza is well-tolerated and can induce impressive ...

Start of Phase I Study for Intranasal Pandemic Influenza Vaccine deltaFLU

... leading experts in the field of live attenuated influenza vaccines. The novel influenza vaccine deltaFLU differs from a conventional influenza vaccine in three major characteristics and in the ...

Sinovac Initiates Phase II Volunteer Enrollment for Split Viron Pandemic Influenza (H5N1) Vaccine

... Phase II clinical trial for its split pandemic influenza vaccine. The preliminary results from this ... reactions in children compared to whole-viron influenza vaccine. Sinovac's split pandemic influenza ... vaccine available in China against the H5N1 influenza virus. About Sinovac Sinovac Biotech Ltd. is ...

Vical Advances RapidResponse(TM) DNA Vaccine Platform Under $6 Million Grant from NIH

... large populations, such as pandemic influenza or severe acute respiratory syndrome (SARS). The ... of the company's Vaxfectin(R)-formulated pandemic influenza DNA vaccines, and expects to release results by ... emerging potentially pandemic disease such as influenza or SARS, an accidental release of a dangerous ...