Fast, Accurate Influenza A/B Antigen Detection
According to CDC data, influenza infections in this country cause more than 114,000 hospitaliz... in elderly and immunocompromised people; however, infections involving fulminant influenza strains are serious illnesses in any patient. Prompt diagnosis of infl......SSA, MRSA) can cause invasive and life-threatening infections such as osteomyelitis, septicemia, endocarditis, a...ecause of inadequate initial antibiotic treatment, infections with health care associated MRSA result in increased costs and worse outcomes compared to infections...West Nile Virus Screening and Diagnostics Technology Emerges In Step with North American Outbreak
...alth departments, established ArboNET to track WNV infections in the US. Data from ArboNet have documented the ...rth America. As of January, 2005, avian or animal infections have been reported from 47 states and Puerto Rico, and human infections have been reported in 40 sta...New Assays to Detect Disseminated Fungal Infections
...ergillus are common concerns. These multi-system infections remain difficult to diagnose and frequently end in death, with mortality rates such as 50% for disseminated candidiasis. As opportunistic infections, these fungi show an affinity for the critically ill, for example in the setting of immunosuppressio...Testing for Human Papillomavirus
...amous cell cancers of the cervix. Most genital HPV infections in women produce transient squamous cell abnormalities of the cervix that are resolved completely, and the probability of any one HPV infection progressing to cervical cancer is quite small. Nevertheless, cervical cancer represents the second most c...Avian (Bird) Flu: Is There a Role for Rapid Tests?
...ponding Editor Harvard Medical School With human infections of bird flu (avian influenza) reported in Asia and...d paucity of human resistance to the H5N1 subtype, infections could then reach pandemic proportions. This is particularly worrisome since the observed case fatal......een as well as clinically significantreductions in infections and thrombocytopenia. In addition asignificant reduction in febrile neutropenia was also observed.Febrile neutropenia is a life-threatening complication ofchemotherapy which often requires hospitalization and antibiotictherapy and may lead to death f......semodifying anti-rheumatic drugs (DMARDs), serious infections havebeen reported in some patients treated with ACTEMRA. About Rheumatoid Arthritis Rheumatoid arthritis is a progressive, systemic autoimmunedisease characterized by inflammation of the membrane lining in thejoints. This inflammation causes a loss......nti-microbial Peptide hLF1-11 for theprevention of infections in hemopoietic stem cell transplantpatients. AM-Pharma is based in Bunnik, The Netherlands with a staff of20. The company is financed by, amongst others, Forbion CapitalPartners, Inventages Venture Capital and Theratase plc. Onceproduct safety and e......tentiallyapplicable for the treatment of long term infections in thecolon. In the placebo controlled, randomize...lenable us to improve a range of products in colon infections andthus better meet patients' requirements." Further analysis of the data is ongoing. About Cosmo ...... development for the treatment ofrespiratory tract infections including CAP. For more information,please visit us on the web at <a target="_blank" href="http://www.advancedlifesciences.com/">http://www.advancedlifesciences.com . Forward-Looking Statements Any statements contained in this press release...Ceragenix Compound Shows Promise for Treating Lethal Cystic Fibrosis Infections
...o treat multidrugresistant Pseudomonas aeuroginosa infections which are a leadingcause of morbidity and mortalit...hout their lifetimes and the repeated bouts oflung infections scar the lung tissue and ultimately rob thepatients of their ability to breathe. "The conventional ...Chi-Med Announces Positive Phase II Proof-of-Concept Data for HMPL-004 in Ulcerative Colitis
...se inChina and South East Asia against respiratory infections andinflammation. This documentation enabled Chi-Med toaccelerate the clinical process for HMPL-004 by by-passing Phase Itrials, based on the FDA’s 2004 guidance on botanical drugproducts. HMPL-004 is currently also in Phase II trial in theUS ...... development for the treatment ofrespiratory tract infections including CAP. For more information,please visit us on the web at <a target="_blank" href="http://www.advancedlifesciences.com/">http://www.advancedlifesciences.com . Forward-Looking Statements Any statements contained in this press release...Vaccine Can Prevent Cervical Cancer and Precancerous Lesions
...V types.The level of protection against persistent infections with HPV16/18at 6 and 12 months was 80·4% and 75·9%, respectively.The study extended earlier results of cross-protection against HPV45 and HPV 31, which cause up to 10% of cases of cervicalcancer. The authors say: "Our results show tha......e that, by preventing the most seriousforms of RSV infections from progressing to its most serious form,Synagis may help protect premature children without chronic lungdisease from recurrent wheezing in the first few years of life,'said Eric Simoes, MD, professor, Department of Pediatric InfectiousDiseases, Uni......ects were manageable and includedhypophosphatemia, infections and thrombocytopenia. No grade 3 orhigher peripheral neuropathy was observed. About Multiple Myeloma Multiple myeloma is the second most common hematologicmalignancy and although the disease is predominantly a cancer ofthe elderly (the average age ......t futureinfections with the same virus types. Some infections persist anddevelop into precancerous lesions, whic...tive and convenientcombination products to prevent infections that cause seriousmedical problems worldwide. In 2006, GSK Bio distributed more than1.1 billion dose...Replidyne Announces Positive Phase I Results for Topical Antibiotic REP8839
...sicians in theongoing fight against drug-resistant infections including MRSA, agrowing public health concern," s...ne antibiotic for treatment ofrespiratory and skin infections in adult and pediatric patients.Replidyne's second drug candidate, REP8839, is a topicalanti-infecti...... Staphylococcus aureus healthcare-associated infections (HAIs) reported to the Centers for Disease C...imated to be more than 2.5 times higher than infections from Staphylococcus aureus that are susceptible to methicillin. -- While there are a few na...Cethromycin Achieves Primary Endpoint in Pivotal Phase 3 Pneumonia Clinical Trial
... the UnitedStates. CAP and other respiratory tract infections are caused bypathogens such as Streptococcus pneum...tly the first-linetreatments for respiratory tract infections such as CAP. Asmacrolide and penicillin resistance grows and has the potential tocause more clinical...BioCryst Presents Phase I Peramivir Data at the Options for the Control of Influenza Conference
...f which at least 157have died. Almost all of these infections are believed to haveresulted from contact with infected poultry. About BioCryst BioCryst Pharmaceuticals, Inc. is a leader in the use ofcrystallography and structure-based drug design for the developmentof novel therapeutics to treat cancer, cardio...... antagonists, including HUMIRA. Many of theserious infections have occurred in patients on concomitantimmunosupp...ent should not be initiated inpatients with active infections until infections are controlled.HUMIRA should not be used by patients with active TB or othersevere ......f congestive heart failure, tuberculosisor serious infections in the study population. Three malignancieswere re...erculosis(TB), sepsis and pneumonia. Some of these infections have beenfatal. Tell your doctor if you have had recent or past exposure topeople with TB. Your doct......semodifying anti-rheumatic drugs (DMARDs), serious infections havebeen reported in some patients treated with ACTEMRA(TM). About Roche Hoffmann-La Roche Inc. (Roche), based in Nutley, N.J., is theU.S. pharmaceuticals headquarters of the Roche Group, one of theworld's leading research-oriented healthcare group......ave aninfection that won't go away or a history of infections that keepcoming back. People who have had tubercu.... The possible serious side effectsinclude serious infections and allergic reactions. Also, rare casesof certain kinds of cancers have been reported. People taki...Anti-TNF Golimumab Continues to Show Promise in Phase II Rheumatoid Arthritis Study
...eaths, cases oftuberculosis or other opportunistic infections were reportedthrough 52 weeks, and serious infections were uncommon. The mostcommon clinically relevant serious AEs through week 52 werepneumonia (three p......ssociated withtherapeutic response. No increase in infections or infectiousevents was observed over time. "We lo...reductions in immunoglobulins, with no increase in infections or infectious events over time. In addition, the 52-Week data showed that, in serologicallyac...Three New Drugs Mark New Era in Rheumatoid Arthritis Treatment
...ab patients on firstinfusion, and rates of serious infections were higher withrituximab patients than those given placebo. Patients takingabatacept had higher incidence of headache, dizziness and seriousinfections than placebo. And some patients taking tocilizumabexperienced headache and skin eruptions, stomati......r malignancies, tuberculosis or otheropportunistic infections were reported. Sixty-one percent ofpatients studie...ble sideeffects of ENBREL include: -0- -- Serious infections -- Many occurred in people prone to infection, such as those with advanced or poorly contro......ases. Idenix'scurrent focus is on the treatment of infections caused by hepatitisB virus, hepatitis C virus and HIV. For further information aboutIdenix, please refer to <a target="_blank" href="http://www.idenix.com/">http://www.idenix.com . Forward-looking Statements This press release contains "for......gram Background Worldwide, over 85 percent of HIV infections are the result ofsexual transmission in which mucosal tissues from the genital andanorectal regions have been exposed to HIV-1 present in semen orsecretions. According to a recent report from the InternationalAIDS Vaccine Initiative, "Since an effect......tients with chronic inflammatorydisorders, chronic infections and inherited diseases such asFamilial Mediterranean Fever. The kidney is the organ mostfrequently affected and progression to dialysis/end-stage renaldisease is the most common clinical manifestation of this disease.Currently, there is no approved t......in the future with these types. Naturallyoccurring infections with cancer-causing virus types may resolve onthei...is previous exposure may not protect againstfuture infections with the same virus types. Some infectionspersist and develop into precancerous lesions, which can a......tive and convenientcombination products to prevent infections that cause seriousmedical problems worldwide. GSK Bio is also developing innovativeimmunotherapy compounds to treat cancer patients. GlaxoSmithKline -- one of the world's leading research-basedpharmaceutical and healthcare companies -- is committed ......perienced grade 3 or 4fatigue (1.7%), grade 3 or 4 infections (4.0%) andpulmonary/respiratory grade 3 or 4 toxicities (3.0%). Preliminary data from Phase 2 trial evaluating satraplatin plusTaxol in non-small cell lung cancer also published in ASCOeducational book Preliminary data from an ongoing Phase 2 trial......perienced grade 3 or 4fatigue (1.7%), grade 3 or 4 infections (4.0%) andpulmonary/respiratory grade 3 or 4 toxicities (3.0%). Preliminary data from Phase 2 trial evaluating satraplatin plusTaxol in non-small cell lung cancer also published in ASCOeducational book Preliminary data from an ongoing Phase 2 trial...Targanta Study Shows Oritavancin Treatment Effective in a Mouse Model of Anthrax
...se 3 studies in complicated skin andskin structure infections (cSSSI) performed by former developersEli Lilly an...ercializing innovativeantibiotics to treat serious infections (either treated oracquired) in the hospital and other institutional settings. Itspipeline includes a......erculosis(TB), sepsis and pneumonia. Some of these infections have beenfatal. Tell your doctor if you have had r...REMICADE are: respiratory infections,such as sinus infections and sore throat, headache, rash, coughing,and stomach pain. Please read the Medication Guide for RE......ailable inEurope for the treatment of ocular viral infections for over 10years. This product has the potential to advance medical treatmentof herpes simplex keratitis in the U.S. Herpes simplex keratitis isa leading cause of corneal blindness in the United States." According to data published in the journal ......million are chronicallyinfected. The number of new infections per year has declined froman average of 240,000 in the 1980s to about 26,000 in 2004. CDCestimates the number of hepatitis C-related deaths could increaseto 38,000 annually by the year 2010, surpassing annual HIV/AIDSdeaths. About PEGASYS PEGASYS, ......nfected with HCV, and three to fourmillion new HCV infections occur annually. The U.S. Centers forDisease Control and Prevention has estimated that in the UnitedStates approximately 3.2 million people are chronically infectedwith HCV and approximately 25,000 new patients are infected eachyear. It is estimated t......ed for approximately 15% of allhospital-associated infections and 27% and 24% of all infectionsacquired in the m...tion Current therapy for these types of pulmonary infections reliesalmost exclusively upon high doses of intravenous antibiotics,which can be associated with sev......UA), held herethis week. Each year, urinary tract infections account for more than eightmillion physician visit...en occur inpeople who are susceptible to bacterial infections because of aweakened immune system. Complicated UTIs also may be caused bystructural or functional d...Data Suggest that Pegasys May be an Option in Hepatitis C Patients Unable to Tolerate Peg-Intron
...million are chronicallyinfected. The number of new infections per year has declined froman average of 240,000 in the 1980s to about 26,000 in 2004. CDCestimates the number of hepatitis C-related deaths could increaseto 38,000 annually by the year 2010, surpassing annual HIV/AIDSdeaths. About PEGASYS PEGASYS, ...Staphylococcus aureus vaccine development on track ? safe and immunogenic in Phase I clinicaltrials
...dquo;. About Staphylococcus aureus and nosocomial infections Hospital?acquired infections are one of the major causes of deathand serious illness worldwide, resulting in an annual burden of ...Migenix to Present Celgosivir Phase II Hepatitis C Results at Digestive Disease Week 2007
...nd preclinical), the prevention ofcatheter-related infections (Phase III) and the treatment ofdermatological diseases (Phase II). MIGENIX is headquartered inVancouver, British Columbia, Canada with US operations in SanDiego, California. Additional information can be found at<a target="_blank" href="http://w......rt of vaccination as well as events thatarose from infections that were acquired after the start ofvaccination. ...as well as the impact of GARDASIL on the course of infections present at the start of the vaccination.Note 4: Table 2 does not include disease due to non-vaccine ......tive and convenient combination productsto prevent infections that cause serious medical problemsworldwide. In 2006, GSK Bio distributed more than 1.1 billion dosesof vaccines to 169 countries in both the developed and thedeveloping world – an average of 3 million doses a day. Ofthose vaccine doses, appro...New England Journal of Medicine Publishes New Data on Gardasil, Merck's Cervical Cancer Vaccine
...cine became more apparent, aslesions caused by new infections with vaccine HPV types wereobserved in the placebo...rt of vaccination as well as events thatarose from infections that were acquired after the start ofvaccination. The impact of GARDASIL in the general populatio...Gardasil Demonstrates Up to 100% Efficacy
...become exposed at some point in life. , , Genital infections with Human Papillomavirus are very common withthe majority of infections occurring in adolescence or earlyadulthood. , EU indication of Gardasil® According to the lice...... to be the leading cause of lower respiratorytract infections in infants in the United States, we are veryencour...tions, the leading cause of lowerrespiratory tract infections in infants in the United States. RSVis the most common respiratory infection in infancy or childhood...Bema Fentanyl Demonstrates Substantial Transmucosal Delivery In Absolute Bioavailability Study
...echnology on Bioral AmphotericinB targeting fungal infections and considering products targeted atother acute conditions including emesis and insomnia in theBEMA(TM) technology. The company's headquarters are located inMorrisville, North Carolina and its principal laboratory is locatedin Newark, New Jersey. For...Alnylam Reports Results of Human Experimental Infection Model with Respiratory Syncytial Virus
...RSV) RSV is a highly contagious virus that causes infections in boththe upper and lower respiratory tract. RSV infects nearly everychild at least once by the age of two years and is a leading causeof hospitalization due to respiratory infection in children and inpeople with compromised immune systems, and othe...Pacgen Announces Positive Results from Phase I/II Trial of Novel Antifungal Drug
...d anti-fungal drug candidate targetingoral Candida infections in immunocompromised patients and patientswith sal...histatin proteins. Current treatments for Candida infections are not effective ineliminating the infection, can have serious side effects, havesignificant potent......biotic, which is used totreat pneumonia, acne, and infections of the skin, genital andurinary systems, and the central nervous system. In a smallproof-of-concept trial of 10 RRMS patients, minocyclinedemonstrated an 84 percent relative reduction in mean totalGd-enhancing lesions and was well tolerated, and data...Data to be presented at AAN Meeting -Study results of drug candidate for MS
... FTY720 weredose-dependent upper respiratory tract infections (mainlynasopharyngitis) and dyspnea, plus diarrhea and nausea. FTY720treatment was associated with initial dose-dependent decreases inheart rate and expiratory air flow. Clinically asymptomaticincreases in alanine aminotransferase (liver enzyme) and ......biotic, which is used totreat pneumonia, acne, and infections of the skin, genital andurinary systems, and the central nervous system. In a smallproof-of-concept trial of 10 RRMS patients, minocyclinedemonstrated an 84 percent relative reduction in mean totalGd-enhancing lesions and was well tolerated, and data...Abbott's Investigational Treatment ABT-874 Shows Positive Results in Phase II Psoriasis Study
...mmation of the nose and pharynx),upper respiratory infections and headache. "We're very excited about these promising Phase II results,"said Eugene Sun, M.D., vice president, Global PharmaceuticalClinical Development at Abbott. "In all but one of the dosinggroups in this study, at least 90 percent of patients ......ons, were balanced betweentreatment groups. Herpes infections were slightly more common inpatients treated with TYSABRI. Serious opportunistic and otheratypical infections have been observed in TYSABRI-treated patients,some of whom were receiving concurrent immunosuppress...