immunity

BioSante Pharmaceuticals Announces New Findings for Potential Bird Flu Vaccine

...es per injection yet still confer a higherlevel of immunity than the currently approved vaccine," saidStephen M. Simes, president and chief executive officer ofBioSante. "These HAI study results confirm the BioVant antibodyresults previously reported and add to the data base for apotential BioSante improved B...

DOR BioPharma Announces Publication Describing Results of Its Multivalent Botulinum Toxin Vaccine BT-VACC

... results are the first thatdescribe the protective immunity elicited by a multivalent vaccinethat is active by the mucosal route. The vaccine consists of acombination of three non-toxic subunits of botulinum toxin thatinduced protection against the corresponding versions of thenatural toxins. The results pub...

Largest Cervical Cancer Vaccine Efficacy Trial Shows Cervarix Provides Excellent Protection Against Lesions Caused by Most Common Cancer-Causing Virus Types

... al. Enhanced humoral and memory B cellular immunity using HPV16/18 L1 VLP vaccine formulated with the MPL/aluminium salt combination (AS04)compared to aluminium salt only. Vaccine 2006 6. Viscidi R, Schiffman M, Hildesheim A, et al. Seroreactivity to Human Papillomavirus (HPV)...

New Flu Vaccine from PepTcell Could Provide Immunity Against All Strains of Influenza Virus

...liminate theneed for annual flu vaccination as the immunity generated targetsregions of the virus that remain ...trains of influenzaviruses to which humans have no immunity develop the ability toreplicate and spread efficiently in humans. Historically, pandemicshave occurr...

New Flu Vaccine From PepTcell Could Provide Immunity Against All Strains of Influenza Virus

...liminate theneed for annual flu vaccination as the immunity generated targetsregions of the virus that remain constant. The results also suggestthat FLU-v has the potential to provide effective protectionagainst a pandemic flu strain by enabling stockpiling and theinitiation of a worldwide vaccination program...

Orchestra Therapeutics Announces New Phase II Clinical Data on NeuroVax Demonstrating Marked Expansion of Regulatory T Cell Populations in Patients With Multiple Sclerosis

...to stimulate strong,disease-specific cell-mediated immunity in nearly all treatedpatients. NeuroVax(TM) appears to work in part by enhancing levelsof Foxp3+ Tregs, which may help regulate expression of pathogenic Tcells in MS patients. The three TCR peptides combined inNeuroVax(TM) correspond to one or more T...

News from the Battlefield of Metastatic Cancer: Epeius Biotechnologies Draws the Sword of Targeted Gene Delivery (Rexin-G) from the Stone of Chemistry and Physics

...ment of cellsinvolved in humoral and cell-mediated immunity in close proximityto the immunizing tumor antigens in a concerted effort to assist intumor eradication and to promote a cancer vaccination in situ.Featuring more than 40 histological plates, from surgical biopsiesand excised tumors, the paper provide...

Cell Genesys Reports Additional Data From Phase 2 Clinical Trial of GVAX Immunotherapy for Pancreatic Cancer

...se-freesurvival and treatment-associated antitumor immunity as measured bythe induction of T cell responses to the pancreaticcancer-associated antigen, mesothelin (p=.01). The new findingswere presented over the weekend by Daniel Laheru, M.D., assistantprofessor of medical oncology at Johns Hopkins Kimmel Can...

Vaxfectin-formulated Measles DNA Vaccine Elicits Long-term Protection and Sterilizing Immunity in Nonhuman Primates

...he Bill andMelinda Gates Foundation. "Sterilizing immunity is a rarely achieved ultimate goal invaccination," said Vijay B. Samant, Vical's President and ChiefExecutive Officer. "The ability to provide such complete immunitywith no adverse events offers proof of concept forVaxfectin(TM)-formulated DNA vaccin...

CytoGenix to Present at 2007 International DNA Vaccines Conference in Spain

...proven to be apotent means of providing protective immunity against viruses,bacteria and parasites in many species from fish to primates. Ouranimal tests demonstrate that DNA vaccines made with synDNA(TM)technology are not only effective in eliciting robust immuneresponses, but also provide protection against...

Data Published in The Lancet Show Gardasil was 100 Percent Effective in Preventing High-Grade Vulvar and Vaginal Lesions Caused by HPV Types 16 and 18

...at levels above baseline (Table 3).The duration of immunity following a complete schedule of immunizationwith GARDASIL has not been established. Table 3Summary of Anti-HPV cLIA Geometric Mean Titers in the PPI* Population-----------------------------------------------------------...

New England Journal of Medicine Publishes New Data on Gardasil, Merck's Cervical Cancer Vaccine

...at levels above baseline (Table 3).The duration of immunity following a complete schedule of immunizationwith GARDASIL has not been established. Table 3Summary of Anti-HPV cLIA Geometric Mean Titers in the PPI* Population-----------------------------------------------------------...

AVI BioPharma Reports Positive Pre-Clinical Influenza Data

...ly one to which the human populationhas no natural immunity and which has the ability to spread easilyfrom person to person. It is believed that emergence of avian fluby this general mechanism may have led to the worldwide pandemicsof 1918, 1957 and 1968. About AVI BioPharma AVI BioPharma develops therapeut...

Anadys Reports Preclinical Data Showing ANA773 Promotes Anti-Tumor Activity of Natural Killer Cells

...on human natural killer (NK) cellactivity. Innate immunity provides the first line of defense against tumorcells by inducing a broad immune response that includes thesecretion of cytokines and the stimulation of NK cells. NK cellsmediate anti-tumor activity by multiple mechanisms. NK cellsdirectly lyse tumor...

Baxter Announces Final Phase I/II Data and Initiation of Phase III Clinical Trial for Candidate Pandemic H5N1 Influenza Vaccine

... low doses, and induces substantiallevels of cross immunity against widely divergent H5N1 strains. Theopen-lab...idate vaccine to inducesubstantial levels of cross immunity against widely divergent H5N1strains. The Phase I/II trial tested four different antigenconcentrati...

New Study Confirms Role for Pertussis Immunization of Entire Family in Reducing Infant Pertussis

...ical communities. This is partly because pertussis immunity fromearly childhood vaccinations eventually wears off, leaving adultsand adolescents susceptible to the disease. The most current datafrom the United States Centers for Disease Control and Prevention(CDC) indicate that the number of pertussis cases i...

Researchers Use Poliovirus to Destroy Neuroblastoma Tumors in Mice

...tly how that immuneresponse occurred. “This immunity against neuroblastoma acquired by theanimals is still something of a mystery, one that we hope toaddress in future studies,” Toyoda said. “But it is anencouraging sign since neuroblastoma are known to relapse quitefrequently.” The ...