Immune in Medical Technology

Study Shows Cancer Vaccines Led to Long-Term Survival for Patients with Metastatic Melanoma and to Long Periods of Disease Control After Completion of Therapy

... derived from patients' own cancer cells and immune cells were well tolerated and resulted in ... with a vaccine that included each patient's own immune cells (dendritic cells) and 500 micrograms of granulocyte-colony stimulating factor (GM-CSF), an immune stimulator, three times a week and then monthly ...

CEL-SCI to Present Data from Multikine Clinical Trials at National Institutes of Health (NIH), National Cancer Institute (NCI) Seminar Series

... and the way Multikine imparts the patient's own immune response with the ability to mount a robust anti-tumor immune response against his/her tumor. Dr. Talor will ... Corporation is developing products that empower immune defenses. Its lead product is Multikine(R) which ...

Proteolix, Inc. Drug Candidate, PR-957, Prevents Disease Progression in Rheumatoid Arthritis Models by Selective Inhibition of the Immunoproteasome

... that contribute to cancer cell growth and immune signaling. It is a proven and validated target ... immunoproteasome, is found in many cells of the immune system. PR-957 selectively targets a subunit of ... of this subunit results in a decrease of the immune cell signaling cascade and a halt of the ...

Tolerx Presents Data at 69th Scientific Sessions of the American Diabetes Association

... diabetes, is a disorder of the body's immune system. In type 1 diabetes, the immune system attacks and destroys the insulin-producing ... candidates, TRX518 and TRX385, that enhance immune responses and are being evaluated for potential ...

CEL SCI Collaborators Demonstrate Novel L.E.A.P.S. Vaccines Immunize Mice Against Tuberculosis Antigens and Suggest Potential to Treat Swine and Other Influenzas

... tuberculosis (TB) antigens can elicit immune responses that would be protective against ... a cytokine that helps regulate the body's immune response, is considered to be a good indicator of ... technology, which induces an effective protective immune response without causing excessive amounts of ...

Peregrine Pharmaceuticals Highlights Promising Early Data From Its Three Phase II Bavituximab Cancer Trials

... a unique mechanism that allows the body's own immune system to recognize and act on the tumor and its ... Once bound, bavituximab alerts the body's immune system to attack the tumor blood vessels, ... of evidence supports the active role of PS in immune signaling, with recent research showing that ...

Three Independent Studies Include the ImmuKnow(R) Assay to Manage and Optimize Immunosuppression Therapy in Transplant Patients

... of the ImmuKnow assay in viral surveillance and immune function monitoring in 35 pediatric renal ... ImmuKnow is a noninvasive biomarker of immune function that assesses cellular immune status by detecting cell-mediated immunity (CMI) ...

Living Donor Kidney Transplants Using Alemtuzumab Pre-Conditioning and Tacrolimus Monotherapy: Long-Term Safety and Efficacy

... ImmuKnow is a noninvasive biomarker of immune function that assesses cellular immune status by detecting cell-mediated immunity (CMI) ... and other clinical indicators when assessing the immune status of any individual patient. About ...

New Therapy Enlists Immune System to Boost Cure Rate in a Childhood Cancer

... experimental therapy using elements of the body's immune system to improve cure rates for children with ... for cancer involves triggering the body's immune system to attack cancer cells. Monoclonal ... signaling proteins that regulate the body's immune responses. In the current study, Children's ...

Aethlon Medical to Present at the 2009 RedChip Small-Cap Investor Conference on June 16, 2009

... a first-in-class artificial adjunct to the immune system proven to capture infectious viruses and ... is a first-in-class artificial adjunct to the immune system proven to capture infectious viruses and ... exosomes that are secreted by tumors to kill-off immune cells. At present, over sixty-five (65) ...

Fate Therapeutics Announces First Patient Treated in Phase 1b Clinical Trial of FT1050 for Hematopoietic Stem Cell Support

... the reconstitution of a patient's blood and immune system." "For patients who need ... and eventually repopulate the patient's blood and immune system. Because FT1050 is believed to affect ... also often destroy the patient's normal blood and immune systems in the process. Therefore, hematopoietic ...

Agennix Receives Fast Track Designation From FDA for Talactoferrin in Combination With Sunitinib for Renal Cell Carcinoma

... associated lymphoid tissue (GALT), the largest immune organ in the body, orally administered ... and Natural Killer T-cells (NK-T) of the innate immune pathway and CD8+ lymphocytes of the adaptive immune pathway. Initiating ...

Novel Vaccine Approach Offers Hope in Fight Against HIV

... used a leapfrog strategy, bypassing the natural immune system response that was the target of all ... used substances aimed at stimulating the body's immune system to produce antibodies or killer cells that ... HIV vaccines have not elicited protective immune responses, just as the body fails on its own to ...

CMC ICOS Biologics and Implicit Bioscience Ltd Announce IC14 Antibody Manufacturing Agreement and Patent License

... infection. CD14 triggers activation of the innate immune response to bacterial components including ... pathway. Lung inflammation in response to innate immune activation through the TLR pathway is a primary ... WA that develops drugs which modulate the host immune response to disease. Its business model is to ...

New Study Shows Probiotic Strain Effective in Boosting Immune Response to Flu Virus

... Bacillus coagulans boosts a key immune marker in healthy people CLEVELAND, May 5 ... coagulans GBI-30, PTA-6086, increases the body's immune response to the flu virus(1). Study data showed ... in T-cell production of TNF-alpha, a key immune marker, versus control upon exposure to influenza ...

Doctors Urge Precaution to Shield Against Swine Flu

... to boost the natural defenses of the body's immune system against strains of influenza. Scientists predict that the aspect of immune defense called "acquired immunity" will also be ... by previous flu illnesses, and stored in the immune system's memory, will be ineffective. Therefore, ...

Data Presented at AUA Demonstrate PROVENGE Significantly Prolongs Survival for Men With Advanced Prostate Cancer in Pivotal Phase 3 IMPACT Study

... but elusive aspiration to harness a patient's own immune system to fight cancer," said Philip Kantoff, MD, ... specifically designed to engage the patient's own immune system against cancer. "The results from ... use live human cells to engage the patient's own immune system with the goal of eliciting a specific ...

An Independent Study Reports on the Utility of ImmuKnow(R), the Cylex(TM) Immune Cell Function Assay, for Monitoring Heart Transplant Recipients

... ) In the largest immune monitoring experience in heart transplantation, ... results suggest that ImmuKnow as a non-invasive immune monitoring is indeed a promising means for ... of the applicability of the ImmuKnow immune function assay in effective management of heart ...

Studies Presented at AACR Annual Meeting Highlight Multiple Immunomodulatory Mechanisms of Peregrine's PS-Targeting Antibodies

... Ability of PS-Targeting Antibodies to Reverse the immune Suppressing Effects of Tumors by Changing the ... and Mobilizing Key Components of the immune System - - Studies Confirm Peregrine's ... One study confirms the anti-tumor effects and immune stimulating ability of a fully human anti-PS ...

New Australian Drug Holds Hope of Major Breakthrough in Treating Terminal Blood Cancers

... -- Australian medical research company immune System Therapeutics Ltd (IST) has launched a ... have shown that the antibody works with the human immune system to induce death of the cancer cells. It is ... 2 9514 4060 Alan Liddle - +61 2 9514 7437 immune System Therapeutics www.ISTL.com.au ...

CEL-SCI Corporation Releases Letter to Shareholders

... proves that it is possible to harness the human immune system against a patient's own cancer. ... a new class of drugs called "Immune SIMULATORS". immune SIMULATORS simulate the way our natural immune system acts in defending us against cancer. As ...

Pharmacyclics Initiates Phase 1 Clinical Trial of Novel Oral Btk Inhibitor for Refractory B-cell Non-Hodgkin's Lymphoma

... may be useful in the treatment of a number of immune mediated diseases. B-cells are a type of white ... normally play an important role in the body's immune response. However, when B-cells are overactive, the immune system produces inflammatory cells and antibodies ...

Study Confirms: Your Hidden Food Allergies Are Making You Fat

... been shown by a unique lab test to excite their immune response. The authors, led by Dr. M. Akmal of the ... avoidance of foods that were shown to be immune reactive according to blood testing through a ... and a pioneer in the study of the hormonal and immune system effects of foods, reviewed the findings ...

Novel Valortim(R) Mechanism of Action Data Presented at the Keystone Symposia on Molecular and Cellular Biology

... Human Dendritic Cell-Mediated Adaptive immune Response to B. Anthraci s. Valortim(R) is a ... anthrax toxin, Valortim(R) augments the immune system's ability to kill anthrax bacilli. In an ... Cross remarked, "These latest studies using human immune cells provide additional evidence of the role of ...

New Hope to Beat Cancer

... cancer research study that trains the patient's immune system to kill cancer cells. (Logo: ... a sample of the tumor. The T cells, which are the immune system's killer cells, are extracted from the ... to attack the cancer cells. The patient's normal immune system is then temporarily suppressed using ...

IBT Laboratories to Launch New Pneumococcal Antibody Avidity Test at AAAAI Meeting, Booth 729

... builds on company's suite of tests to evaluate immune function LENEXA, Kan., March 12 /PRNewswire/ ... on the company's suite of assays evaluating immune function. "IBT Laboratories was one of the first ... into the strengths and weaknesses of a patient's immune system." IBT offers the widest range of ...

Laser Burn Injuries in One Eye Can Disrupt Protective Immune Privilege in Both Eyes, Study Finds

... to lose a special protective ability known as immune privilege. immune privilege protects the eye without the inflammation of the body's normal immune response, which can further damage delicate eye ...

BN ImmunoTherapeutics Updates on Phase I/II Studies With Breast Cancer Vaccine

... response. Evidence of vaccine-induced anti-HER2 immune response was detected in approximately 70% of ... HER2 positive breast cancer; however the overall immune response was moderate. Additionally BN ... new vaccine induced up to 20-fold higher T-cell immune response as compared to the original version. ...

Update of Long-Term Data on Brain Cancer Patients Receiving DCVax(R)-Brain Continues to Show Striking Improvements in Delay of Disease and Survival

... vaccine that takes a patient's own master immune cells and the biomarkers from that patient's own tumor tissue, and activates the master immune cells so they can mobilize the full immune system to recognize and kill the tumor cells. The ...

Nplate(R) Approved in the European Union for the Treatment of Chronic Immune (Idiopathic) Thrombocytopenic Purpura (ITP)

... for the treatment of splenectomised adult chronic immune (idiopathic) thrombocytopenic purpura (ITP) ... bleeding - are destroyed by the patient's own immune system. Low platelet counts leave adult ITP ... T, Epidemiology and pathophysiology of immune thrombocytopenic purpura. European Journal of ...

Scientists Unmask Genetic Markers Associated With Psoriasis

... the role of several genes in mediating the immune responses that result in psoriasis," says Goncalo ... three genes may predispose people to chronic immune responses that ultimately result in psoriasis. ... with psoriasis. Together, these genes limit immune responses. Genetic alterations in this "brake" ...

Study Demonstrates that AHCC(R) Enhances Immune System by Increasing the Production of Key Dendritic Cells

... significance of AHCC for maintaining a healthy immune system PURCHASE, N.Y., Jan. 6 /PRNewswire/ ... AHCC (Active Hexose Correlated Compound) enhances immune function by increasing the number of dendritic cells (DCs). DCs are a key part of the immune system responsible for presenting foreign ...

Novavax Announces Top Line Results of Phase IIa Clinical Trial for Its Seasonal Influenza VLP (Trivalent) Vaccine Candidate

... but also anti-neuraminidase and cell mediated immune responses. We believe these attributes of the ... wild-type virus, they are able to induce potent immune response. Novavax's VLP vaccine may be ... viral proteins important for inducing a broad immune response including two surface proteins, ...

SARS Vaccine Achieves Neutralizing Responses in First U.S. Human Trial

... CD4+ T cells help direct the appropriate immune resources against specific pathogens. CD8+ T ... part of the pathogen itself, and can prime the immune system as well as induce antibody and ... administered on a repeat basis without unwanted immune responses. Additionally, DNA vaccines have the ...

Long-term Follow Up Interim Data Show Nplate(TM) Increased and Sustained Platelet Counts in Adult Chronic ITP Patients

... (romiplostim) in adult patients with chronic immune thrombocytopenic purpura (ITP). Chronic ITP is ... -- are destroyed by the patient's own immune system. Low platelet counts leave adult ITP ... of thrombocytopenia in patients with chronic immune (idiopathic) thrombocytopenic purpura (ITP) who ...

Kiadis Pharma Announces Positive Clinical Results for ATIR(TM) in Mismatched Bone Marrow Transplantations

... Graft versus Host Disease (GvHD) and allow early immune reconstitution following a mismatched bone marrow ... on the study. "Our study shows a rapid immune reconstitution in transplanted patients provided with ATIR(TM) treated immune cells from mismatched donors. Without ATIR(TM) ...

IBT Laboratories Expands its Menu of Tests for Immune Deficiency

... tests to evaluate the response of patients whose immune systems may be compromised due to a primary ... than was possible before. "We rely on our body's immune system to defend us from infectious disease. When ... assessment of the capabilities of the patient's immune system to respond to challenge by microorganisms. ...

Nplate(TM) (Romiplostim) Receives Positive Opinion for Marketing Authorisation in the European Union

... The CHMP recommends Nplate for adult chronic immune (idiopathic) thrombocytopenia purpura (ITP) ... that increases platelet production and avoids immune suppression in adult chronic ITP patients," ... -- are destroyed by the patient's own immune system. Low platelet counts leave adult ITP ...

Over $10 Million of CSL Behring's Privigen Was Sold in the U.S. During the Third Quarter of 2008

... 2008. Privigen is the newest brand of intravenous immune globulin (IVIG) and was launched in the ... of thousands of donors and is used to treat immune deficiencies, inflammatory and autoimmune ... monitor hospital utilization rates of intravenous immune globulin products. The data captured in this ...

Vical Completes Enrollment and Reports Positive Interim Data in CMV Vaccine Phase 2 Trial

... in developing countries. While a healthy immune system typically protects an infected person ... eliminating the infection, and those whose immune systems are not fully functional are at high risk ... can induce both antibody and cellular immune responses, but pose a potential safety concern, ...