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Hormone in Medical Technology

TWO NEW KLRI PEER-REVIEWED PUBLICATIONS: Hormone Therapy May Reduce Atherosclerosis in Women Close to Menopause; Growth Hormone May Increase Risk of Diabetes, Improve Lipid Profile in Men

... (KLRI) has published two new publications on hormone therapies and their effects on reducing the risks ... that there are certain benefits to menopausal hormone therapy (HT) in newly postmenopausal women, but ... DC VA Medical Center, tests the effects of growth hormone (GH) therapy, both combined with sex steroids and ...

Estrogen Getting Cool Reception From Dermatologists for Mixed Results in Improving Appearance of Skin

... 29 /PRNewswire-USNewswire/ -- For many women, hormone replacement therapy (HRT) can alleviate the ... and vaginal changes -- physicians often prescribe hormone replacement therapy (HRT) to boost the body's ... For example, one study examined whether low-dose hormone therapy improved aging skin in 485 women who were ...

Bionovo's Estrogen Receptor Beta Selective Drugs Have Unique Gene Expression and Cell Type Specificity

... ERb selective compounds compared to the natural hormone estradiol, which non-selectively regulates both ... a number of genes differently than estradiol, a hormone therapy commonly used to treat women's health ... might be safer than current estrogens used in hormone therapy. The study also demonstrates the cell ...

Neurocrine Biosciences Presents Elagolix Data

... "An orally active gonadotropin releasing hormone antagonist with no long-term bone risk would be a ... in the treatment of endometriosis and other hormone dependent diseases. These safety results support ... to examine the impact of a gonadotropin releasing hormone (GnRH) antagonist on prostate tissue. The animal ...

When It Comes to Natural Remedies for Hormonal Balance, the Proof Is in the Clinical Research

... Femmenessence: Proven to Regulate hormone Levels in Women SAN FRANCISCO, June 12 ... and exiting menopause are in a bind. As hormone levels fluctuate and decline, they experience a ... limited. Researchers reported in 2002 that the hormone replacement therapy Prempro(R), which introduces ...

Scientists at The Karmanos Cancer Institute in Detroit Identify Potential New Target for Breast Cancer Therapy

... a promising new therapeutic target for aggressive hormone receptor negative breast cancer tumors. ... Karmanos scientists tested 84 cases of hormone receptor negative human breast carcinomas and ... EZH-2 was expressed in 74 percent of those cases. hormone receptor negative breast carcinoma is considered ...

Genomic Health Study Shows Breast Cancers in Men Display Very Similar Gene Signatures to Those in Women

... cancer patients had higher mean expression of the hormone receptor genes, likely due to the different ... of triple-negative breast cancer compared with hormone receptor-positive disease, as well as the ... gene expression between the triple negative and hormone receptor positive groups, including genes for ...

Ongoing Landmark ROADMAP Study Demonstrates Significant Improvement in Blood Pressure Control at One Year, According to Blinded Results

... Olmesartan Medoxomil Angiotensin II is a hormone that interacts with a receptor on arterial blood ... angiotensin II stimulates the release of another hormone that causes enhanced sodium and chloride (salt) ... blood vessels and antagonizing the release of the hormone which causes salt retention and increased blood ...

New Data Shows Blood Pressure Reduction Therapy with BENICAR(R) and BENICAR HCT(R) Effectively Reduces Blood Pressure in Elderly Patients to Target Blood Pressure

... (R) and BENICAR HCT (R) Angiotensin II is a hormone that interacts with a receptor on arterial blood ... angiotensin II stimulates the release of another hormone that causes enhanced sodium and chloride (salt) ... blood vessels and antagonizing the release of the hormone which causes salt retention and increased blood ...

Methadone Frequently Causes Menopausal Symptoms in Young Women

... estradiol, progesterone and testosterone hormone levels to menopausal levels, even in women less ... with estradiol, progesterone or testosterone hormone levels, in the post menopausal range." A ... often decrease rapidly, with bioidentical hormone replacement. Bone density increases exceeding ...

Ferring Pharmaceuticals Launches Phase IIIB Trial of Degarelix as Intermittent Therapy

... a new injectable gonadotropin-releasing hormone (GnRH) receptor antagonist approved by the U.S. ... Drug Administration (FDA) for the treatment of hormone sensitive advanced prostate cancer. The ... Degarelix is an injectable gonadotropin-releasing hormone (GnRH) receptor antagonist approved by the U.S. ...

Radius Initiates Phase 2a Clinical Trial of RAD1901 in Menopausal Hot Flashes

... symptoms without side effects associated with hormone therapy-- CAMBRIDGE, Mass., March 24 ... flashes, without the side effects associated with hormone therapy. We look forward to reporting the results ... markers of estrogen effect--follicle-stimulating hormone (FSH), ...

Ambrx and Merck Serono Expand Collaboration Through ARX424 Multiple Sclerosis Drug Development Alliance

... to develop ARX201, Ambrx's long-acting growth hormone product, currently in Phase II of clinical ... suited to harness the potential of our growth hormone and multiple sclerosis product candidates given ... candidate, ARX201, is a long-acting human growth hormone drug candidate partnered with Merck Serono that ...

Video: Zometa(R) Reduces Risk of Breast Cancer Recurrence in Premenopausal Women, Study in The New England Journal of Medicine Reports

... - Adding Zometa to post-surgery hormone therapy reduced risk of breast cancer return or death by 36% more than hormone therapy alone - First Phase III data to ... (zoledronic acid) along with post-surgery hormone therapy provided a reduction in risk of ...

Modigene Announces Positive Results of Pilot Toxicity Study of Its Long-Acting Human Growth Hormone hGH-CTP

... safety of hGH-CTP, its long-acting human growth hormone (hGH), as well as to provide preliminary ... that was 1,040 times the daily dose of growth hormone recommended for use in human patients. No ... indications for hGH in children are growth hormone deficiency, kidney disease, Prader-Willi Syndrome ...

New Study First to Confirm Sandostatin LAR(R) Depot Controls Tumor Growth in Patients With Rare Gastrointestinal Tumors

... life-threatening symptoms (syndromes) caused by hormone secretion and to extend patient survival by ... effects on the human body as the natural hormone somatostatin. However, octreotide is even more ... reduces and in many cases can normalize growth hormone and/or IGF-1 levels in patients with acromegaly, ...

Video: Femara(R) First Aromatase Inhibitor to Indicate Survival Benefit Versus Tamoxifen When Taken for Five Years After Breast Cancer Surgery

... study reports that postmenopausal woman with hormone receptor-positive early-stage breast cancer who ... (from randomization) revealed that sequencing hormone therapy following surgery is not superior to five ... surgery) treatment of postmenopausal women with hormone receptor-positive early stage breast cancer. The ...

VAI Finding Could Lead to New Drugs for Anxiety, Depression

... Van Andel Institute (VAI) have determined how the hormone corticotrophin releasing factor (CRF) ... necessary to develop an ideal drug." CRF is a hormone and neurotransmitter secreted by the hypothalamus ... that binds to the hormone, which allows the hormone to activate changes in the cell. Using a ...

BN ImmunoTherapeutics Announces Positive Mature Phase II Results From Newly Acquired Prostate Cancer Vaccine

... far in disseminated disease with some effect is hormone treatment. hormone therapy slows the tumor growth by stopping or ... factors. Thus, although initially effective, hormone therapy becomes ineffective after a period of ...

Bavarian Nordic Announces Positive Mature Phase II Results From Newly Acquired Prostate Cancer Vaccine

... far in disseminated disease with some effect is hormone treatment. hormone therapy slows the tumor growth by stopping or ... factors. Thus, although initially effective, hormone therapy becomes ineffective after a period of ...

Study Shows Benefits of a High Omega-3 Diet in Older Adults

... in Hormones and Metabolic Research. "As we age, hormone secretion and cell responsiveness ... have shown that omega-3 fatty acids may help hormone signals get into cells whose cell membrane has ... in omega-3 fatty acids on the loss of normal hormone balance that occurs during normal aging. KLRI ...

Modigene Platform Validated in Independent Phase III Trial of CTP Technology

... to extend the duration of action of human growth hormone and interferon beta, with the goal of reducing ... Phase III trial of its long-acting FSH fertility hormone marks a major milestone for the CTP ... Modigene's CTP-enhanced versions of human growth hormone and interferon beta that we intend to initiate ...

New Study Shows BENICAR(R) (olmesartan medoxomil) Reverses Blood Vessel Damage Independent of Blood Pressure Lowering

... BENICAR and BENICAR HCT Angiotensin II is a hormone that interacts with a receptor on arterial blood ... angiotensin II stimulates the release of another hormone that causes enhanced sodium and chloride (salt) ... blood vessels and antagonizing the release of the hormone which causes salt retention and increased blood ...

Video: Major Independent Trial Demonstrates Significant Anticancer Benefit of Zometa(R) in Women With Early-Stage Breast Cancer

... - Zometa when added to hormone therapy, following surgery, significantly ... beyond clinical benefits achieved with hormone therapy alone(1) - Findings may allow ... The study found that Zometa when added to hormone therapy, following surgery, significantly reduced ...

New Data Shows 45 Percent of Patients with Stage 1 Hypertension Reached Normotension with BENICAR(R) and BENICAR HCT(R)

... BENICAR and BENICAR HCT Angiotensin II is a hormone that interacts with a receptor on arterial blood ... angiotensin II stimulates the release of another hormone that causes enhanced sodium and chloride (salt) ... blood vessels and antagonizing the release of the hormone which causes salt retention and increased blood ...

Amylin Pharmaceuticals Initiates Phase 2B Dose-Ranging Clinical Study of Pramlintide/Metreleptin Combination Treatment in Obesity

... of pramlintide, an analog of the natural hormone amylin, and recombinant human leptin ... Studies." "Leptin is a fundamentally important hormone in energy metabolism with a unique role in ... scientific basis for the development of peptide hormone combinations, and provide renewed hope ...

NPS Reports Successful GATTEX(TM) Extension Study

... short bowel syndrome and NPSP558 (parathyroid hormone 1-84 [rDNA origin] injection) is in Phase 2 clinical development as a hormone therapy for hypoparathyroidism. NPS has also ... 3 osteoporosis study for PREOS(R) (parathyroid hormone 1-84 [rDNA origin] injection). NPS complements ...

Outcomes Vary for Prostate Cancer Patients Choosing Surgery; Overall, No Treatment Proven Superior

... radical prostatectomy); testicle removal or hormone therapy (androgen deprivation therapy); ... ultrasound or radiation therapy. -- Adding hormone therapy prior to prostate removal does not ... events. -- Combining radiation with hormone therapy may decrease mortality. But compared with ...

Multiple Studies Presented at San Antonio Breast Cancer Symposium Reinforce Clinical Utility of Oncotype DX(R)

... postmenopausal patients with node positive, hormone receptor-positive breast cancer who were treated ... DX may be clinically useful in some patients with hormone receptor positive, node-positive breast ... of chemotherapy use among node-negative, hormone receptor-positive patients treated in 2003 ...

Indevus Pharmaceuticals Reports Positive Results of Phase II Octreotide Implant Trial

... characterized by excessive blood levels of growth hormone (GH) and insulin- like growth factor 1 (IGF-1). ... implants and evaluated the suppression of growth hormone (GH) and insulin-like growth factor 1 (IGF-1). ... hormone somatostatin to block release of growth hormone (GH), over a six month period. About Indevus ...

Medivation's MDV3100 Demonstrates Substantial PSA Reductions in First Patient Groups Treated in Phase 1-2 Hormone Refractory Prostate Cancer Trial

... cancers can still be sensitive to alternative hormone therapies like MDV3100," said the study's ... PSA declines experienced to date by our first six hormone refractory prostate cancer patients treated with ... to enter pivotal Phase 3 registration studies in hormone refractory prostate cancer. ...

Genomic Health Announces Preliminary Results From a Study of Oncotype DX(TM) in Node-Positive Breast Cancer Patients

... DX in postmenopausal women with node-positive, hormone receptor positive breast cancer conducted by the ... patients with node-positive, hormone receptor positive breast cancer who were treated ... be clinically useful in some patients with hormone receptor positive, node-positive breast cancer. ...

Norditropin(R) Approved for Treatment of Children with Short Stature Associated with Turner Syndrome

... due to inadequate secretion of endogenous growth hormone and for replacement of endogenous growth hormone in adults with growth hormone deficiency (GHD) who meet either of the following ...

Norditropin(R) Approved for Treatment of Children with Short Stature Associated with Turner Syndrome

... due to inadequate secretion of endogenous growth hormone and for replacement of endogenous growth hormone in adults with growth hormone deficiency (GHD) who meet either of the following ...

New Data Supports Significant Economic and Clinical Value of MENOPUR(R) in IVF

... offered considerable cost-savings over recombinant follicle stimulating hormone (rFSH).[1] The cost-effectiveness of HP-hMG compared with rFSH suggested ... of highly purified menotropin versus recombinant follicle-stimulating hormone in in vitro fertilization/intracytoplasmic sperm injection cycles: a ...

The Lancet Publishes Direct Comparison Study Between Liraglutide and Exenatide

... has a leading position within areas such as hemostasis management, growth hormone therapy and hormone replacement therapy. Novo Nordisk manufactures and markets pharmaceutical ...

Two-Year Data Show Investigational Drug Liraglutide More Effective at Lowering Blood Sugar Than Glimepiride: Oral 162

... has a leading position within areas such as hemostasis management, growth hormone therapy and hormone replacement therapy. Novo Nordisk manufactures and markets pharmaceutical ...

Video: Data on More Than 15 Novartis Oncology Compounds at ASCO Highlight Progress Toward Targeted Therapies for Diverse Tumor Types

... [letrozole tablets] vs. tamoxifen) found that postmenopausal women with hormone receptor-positive early breast cancer taking adjuvant Femara had better ... octreotide substantially reduces and in many cases can control growth hormone and/or normalize IGF-1 levels in patients with acromegaly, a disease ...

Melanoma and Pregnancy: What Every Woman Needs to Know About the Risks, Prognosis

... observed the effect of hormones received from external sources -- such as hormone replacement therapy (HRT) or oral contraceptive pills (OCPs) -- have found ... Cancer followed 206 women diagnosed with localized melanoma who received hormone replacement therapy within five years of being diagnosed with melanoma. ...

First Candidate from Esperance's Targeted Anti-cancer Platform, EP-100, Establishes Preclinical Proof of Concept

... peptide and is designed to selectively target luteinizing hormone releasing hormone (LHRH) receptors, which are overexpressed in a wide range of cancers. ...
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(Date:11/26/2009)...are the bare essentials of life, the indispensable...urvive on its own? Can we describe the molecular a...anism functions as a system? These are just some o...etween the European Molecular Biology Laboratory (...gulacio Genmica (CRG) in Barcelona, Spain, set out...
(Date:11/25/2009)...fficers and ambulance workers faced a terrifying r...ey battled to save people from the collapsing Twin... evacuated as many people as they could in an area...aking their jobs even harder was the problem of po...latives jammed mobile networks with calls and the ...
(Date:11/25/2009)...as vital to your health as what you eat, found res...ies. Their experiments in mice revealed that the d...e liverthe body,s metabolic clearinghouseis mostly...ircadian clock as conventional wisdom had it. , ...ge number of genes completely independent of the c...
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(Date:11/25/2009)...Newswire-FirstCall/ -- Onyx Pharmaceuticals, Inc...y will host two investor events in December: ,,... a.m. CT/10:00 a.m. ET ,, Principal investiga...arfilzomib in relapsed and/or refractory multiple ...of Hematology (ASH) Annual Meeting and Exposition ...
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