TWO NEW KLRI PEER-REVIEWED PUBLICATIONS: Hormone Therapy May Reduce Atherosclerosis in Women Close to Menopause; Growth Hormone May Increase Risk of Diabetes, Improve Lipid Profile in Men
... (KLRI) has published two new publications on
hormone therapies and their effects on reducing the risks ... that there are certain benefits to menopausal
hormone therapy (HT) in newly postmenopausal women, but ... DC VA Medical Center, tests the effects of growth
hormone (GH) therapy, both combined with sex steroids and ...
Estrogen Getting Cool Reception From Dermatologists for Mixed Results in Improving Appearance of Skin
... 29 /PRNewswire-USNewswire/ -- For many women,
hormone replacement therapy (HRT) can alleviate the ... and vaginal changes -- physicians often prescribe
hormone replacement therapy (HRT) to boost the body's ... For example, one study examined whether low-dose
hormone therapy improved aging skin in 485 women who were ...
Bionovo's Estrogen Receptor Beta Selective Drugs Have Unique Gene Expression and Cell Type Specificity
... ERb selective compounds compared to the natural
hormone estradiol, which non-selectively regulates both ... a number of genes differently than estradiol, a
hormone therapy commonly used to treat women's health ... might be safer than current estrogens used in
hormone therapy. The study also demonstrates the cell ...
Neurocrine Biosciences Presents Elagolix Data
... "An orally active gonadotropin releasing
hormone antagonist with no long-term bone risk would be a ... in the treatment of endometriosis and other
hormone dependent diseases. These safety results support ... to examine the impact of a gonadotropin releasing
hormone (GnRH) antagonist on prostate tissue. The animal ...
When It Comes to Natural Remedies for Hormonal Balance, the Proof Is in the Clinical Research
... Femmenessence: Proven to Regulate
hormone Levels in Women
SAN FRANCISCO, June 12 ... and exiting menopause are in a bind. As
hormone levels fluctuate and decline, they experience a ... limited. Researchers reported in 2002 that the
hormone replacement therapy Prempro(R), which introduces ...
Scientists at The Karmanos Cancer Institute in Detroit Identify Potential New Target for Breast Cancer Therapy
... a promising new therapeutic target for aggressive
hormone receptor negative breast cancer tumors.
...
Karmanos scientists tested 84 cases of
hormone receptor negative human breast carcinomas and ... EZH-2 was expressed in 74 percent of those cases.
hormone receptor negative breast carcinoma is considered ...
Genomic Health Study Shows Breast Cancers in Men Display Very Similar Gene Signatures to Those in Women
... cancer patients had higher mean expression of the
hormone receptor genes, likely due to the different ... of triple-negative breast cancer compared with
hormone receptor-positive disease, as well as the ... gene expression between the triple negative and
hormone receptor positive groups, including genes for ...
Ongoing Landmark ROADMAP Study Demonstrates Significant Improvement in Blood Pressure Control at One Year, According to Blinded Results
... Olmesartan Medoxomil
Angiotensin II is a
hormone that interacts with a receptor on arterial blood ... angiotensin II stimulates the release of another
hormone that causes enhanced sodium and chloride (salt) ... blood vessels and antagonizing the release of the
hormone which causes salt retention and increased blood ...
New Data Shows Blood Pressure Reduction Therapy with BENICAR(R) and BENICAR HCT(R) Effectively Reduces Blood Pressure in Elderly Patients to Target Blood Pressure
... (R) and BENICAR HCT (R)
Angiotensin II is a
hormone that interacts with a receptor on arterial blood ... angiotensin II stimulates the release of another
hormone that causes enhanced sodium and chloride (salt) ... blood vessels and antagonizing the release of the
hormone which causes salt retention and increased blood ...
Methadone Frequently Causes Menopausal Symptoms in Young Women
... estradiol, progesterone and testosterone
hormone levels to menopausal levels, even in women less ... with estradiol, progesterone or testosterone
hormone levels, in the post menopausal range."
A ... often decrease rapidly, with bioidentical
hormone replacement. Bone density increases exceeding ...
Ferring Pharmaceuticals Launches Phase IIIB Trial of Degarelix as Intermittent Therapy
... a new injectable gonadotropin-releasing
hormone (GnRH) receptor antagonist approved by the U.S. ... Drug Administration (FDA) for the treatment of
hormone sensitive advanced prostate cancer. The ... Degarelix is an injectable gonadotropin-releasing
hormone (GnRH) receptor antagonist approved by the U.S. ...
Radius Initiates Phase 2a Clinical Trial of RAD1901 in Menopausal Hot Flashes
... symptoms without side effects associated with
hormone therapy--
CAMBRIDGE, Mass., March 24 ... flashes, without the side effects associated with
hormone therapy. We look forward to reporting the results ... markers of estrogen effect--follicle-stimulating
hormone (FSH), ...
Ambrx and Merck Serono Expand Collaboration Through ARX424 Multiple Sclerosis Drug Development Alliance
... to develop ARX201, Ambrx's long-acting growth
hormone product, currently in Phase II of clinical ... suited to harness the potential of our growth
hormone and multiple sclerosis product candidates given ... candidate, ARX201, is a long-acting human growth
hormone drug candidate partnered with Merck Serono that ...
Video: Zometa(R) Reduces Risk of Breast Cancer Recurrence in Premenopausal Women, Study in The New England Journal of Medicine Reports
... - Adding Zometa to post-surgery
hormone therapy reduced risk of breast cancer return or death by 36% more than
hormone therapy alone
- First Phase III data to ... (zoledronic acid) along with post-surgery
hormone therapy provided a reduction in risk of ...
Modigene Announces Positive Results of Pilot Toxicity Study of Its Long-Acting Human Growth Hormone hGH-CTP
... safety of hGH-CTP, its long-acting human growth
hormone (hGH), as well as to provide preliminary ... that was 1,040 times the daily dose of growth
hormone recommended for use in human patients. No ... indications for hGH in children are growth
hormone deficiency, kidney disease, Prader-Willi Syndrome ...
New Study First to Confirm Sandostatin LAR(R) Depot Controls Tumor Growth in Patients With Rare Gastrointestinal Tumors
... life-threatening symptoms (syndromes) caused by
hormone secretion and to extend patient survival by ... effects on the human body as the natural
hormone somatostatin. However, octreotide is even more ... reduces and in many cases can normalize growth
hormone and/or IGF-1 levels in patients with acromegaly, ...
Video: Femara(R) First Aromatase Inhibitor to Indicate Survival Benefit Versus Tamoxifen When Taken for Five Years After Breast Cancer Surgery
... study reports that postmenopausal woman with
hormone receptor-positive early-stage breast cancer who ... (from randomization) revealed that sequencing
hormone therapy following surgery is not superior to five ... surgery) treatment of postmenopausal women with
hormone receptor-positive early stage breast cancer. The ...
VAI Finding Could Lead to New Drugs for Anxiety, Depression
... Van Andel Institute (VAI) have
determined how the
hormone corticotrophin releasing factor (CRF) ... necessary to develop an ideal drug."
CRF is a
hormone and neurotransmitter secreted by the hypothalamus ... that binds to the
hormone, which allows the
hormone to activate changes in the cell.
Using a ...
BN ImmunoTherapeutics Announces Positive Mature Phase II Results From Newly Acquired Prostate Cancer Vaccine
... far in disseminated disease with some
effect is
hormone treatment.
hormone therapy slows the tumor growth by
stopping or ... factors. Thus, although initially effective,
hormone therapy becomes
ineffective after a period of ...
Bavarian Nordic Announces Positive Mature Phase II Results From Newly Acquired Prostate Cancer Vaccine
... far in disseminated disease with some
effect is
hormone treatment.
hormone therapy slows the tumor growth by
stopping or ... factors. Thus, although initially effective,
hormone therapy becomes
ineffective after a period of ...
Study Shows Benefits of a High Omega-3 Diet in Older Adults
... in Hormones and Metabolic Research.
"As we age,
hormone secretion and cell responsiveness ... have shown that
omega-3 fatty acids may help
hormone signals get into cells whose cell
membrane has ... in omega-3 fatty acids on the loss of normal
hormone balance that
occurs during normal aging. KLRI ...
Modigene Platform Validated in Independent Phase III Trial of CTP Technology
... to extend the duration of action
of human growth
hormone and interferon beta, with the goal of reducing ... Phase III trial of its long-acting
FSH fertility
hormone marks a major milestone for the CTP ... Modigene's
CTP-enhanced versions of human growth
hormone and interferon beta that we
intend to initiate ...
New Study Shows BENICAR(R) (olmesartan medoxomil) Reverses Blood Vessel Damage Independent of Blood Pressure Lowering
... BENICAR and BENICAR HCT
Angiotensin II is a
hormone that interacts with a receptor on arterial
blood ... angiotensin II stimulates the release of another
hormone that
causes enhanced sodium and chloride (salt) ... blood vessels and antagonizing the release
of the
hormone which causes salt retention and increased blood ...
Video: Major Independent Trial Demonstrates Significant Anticancer Benefit of Zometa(R) in Women With Early-Stage Breast Cancer
... - Zometa when added to
hormone therapy, following surgery, significantly ... beyond clinical benefits achieved with
hormone therapy alone(1) - Findings may allow ... The study found that Zometa when added to
hormone therapy,
following surgery, significantly reduced ...
New Data Shows 45 Percent of Patients with Stage 1 Hypertension Reached Normotension with BENICAR(R) and BENICAR HCT(R)
... BENICAR and BENICAR HCT
Angiotensin II is a
hormone that interacts with a receptor on arterial
blood ... angiotensin II stimulates the release of another
hormone that
causes enhanced sodium and chloride (salt) ... blood vessels and antagonizing the release
of the
hormone which causes salt retention and increased blood ...
Amylin Pharmaceuticals Initiates Phase 2B Dose-Ranging Clinical Study of Pramlintide/Metreleptin Combination Treatment in Obesity
... of pramlintide, an analog of the
natural
hormone amylin, and recombinant human leptin ... Studies."
"Leptin is a fundamentally important
hormone in energy metabolism with
a unique role in ... scientific basis for the
development of peptide
hormone combinations, and provide renewed hope ...
NPS Reports Successful GATTEX(TM) Extension Study
... short bowel
syndrome and NPSP558 (parathyroid
hormone 1-84 [rDNA origin] injection) is
in Phase 2 clinical development as a
hormone therapy for
hypoparathyroidism. NPS has also ... 3 osteoporosis study for
PREOS(R) (parathyroid
hormone 1-84 [rDNA origin] injection). NPS
complements ...
Outcomes Vary for Prostate Cancer Patients Choosing Surgery; Overall, No Treatment Proven Superior
... radical prostatectomy); testicle
removal or
hormone therapy (androgen deprivation therapy); ... ultrasound or radiation therapy.
-- Adding
hormone therapy prior to prostate removal does not ... events.
-- Combining radiation with
hormone therapy may decrease mortality. But
compared with ...
Multiple Studies Presented at San Antonio Breast Cancer Symposium Reinforce Clinical Utility of Oncotype DX(R)
... postmenopausal patients with node positive,
hormone receptor-positive breast cancer who were treated ... DX may be clinically useful in some patients with
hormone receptor positive, node-positive breast ... of chemotherapy use among node-negative,
hormone receptor-positive patients treated in 2003 ...
Indevus Pharmaceuticals Reports Positive Results of Phase II Octreotide Implant Trial
... characterized by excessive blood levels of growth
hormone (GH) and
insulin- like growth factor 1 (IGF-1). ... implants and evaluated the
suppression of growth
hormone (GH) and insulin-like growth factor 1
(IGF-1). ... hormone
somatostatin to block release of growth
hormone (GH), over a six month
period.
About Indevus
...
Medivation's MDV3100 Demonstrates Substantial PSA Reductions in First Patient Groups Treated in Phase 1-2 Hormone Refractory Prostate Cancer Trial
... cancers can still be sensitive to
alternative
hormone therapies like MDV3100," said the study's ... PSA declines experienced to date by our
first six
hormone refractory prostate cancer patients treated with ... to enter
pivotal Phase 3 registration studies in
hormone refractory prostate cancer. ...
Genomic Health Announces Preliminary Results From a Study of Oncotype DX(TM) in Node-Positive Breast Cancer Patients
... DX in postmenopausal women with node-positive,
hormone receptor
positive breast cancer conducted by the ... patients with node-positive,
hormone receptor positive
breast cancer who were treated ... be clinically useful in some patients with
hormone receptor positive,
node-positive breast cancer. ...
Norditropin(R) Approved for Treatment of Children with Short Stature Associated with Turner Syndrome
... due to
inadequate secretion of endogenous growth
hormone and for replacement of
endogenous growth
hormone in adults with growth
hormone deficiency (GHD)
who meet either of the following ...
Norditropin(R) Approved for Treatment of Children with Short Stature Associated with Turner Syndrome
... due to
inadequate secretion of endogenous growth
hormone and for replacement of
endogenous growth
hormone in adults with growth
hormone deficiency (GHD)
who meet either of the following ...
New Data Supports Significant Economic and Clinical Value of MENOPUR(R) in IVF
... offered considerable cost-savings over recombinant
follicle stimulating
hormone (rFSH).[1] The cost-effectiveness of HP-hMG
compared with rFSH suggested ... of highly
purified menotropin versus recombinant follicle-stimulating
hormone in in
vitro fertilization/intracytoplasmic sperm injection cycles: a ...
The Lancet Publishes Direct Comparison Study Between Liraglutide and Exenatide
... has a leading position within areas such as hemostasis management, growth
hormone therapy and
hormone replacement therapy. Novo Nordisk manufactures and markets pharmaceutical ...
Two-Year Data Show Investigational Drug Liraglutide More Effective at Lowering Blood Sugar Than Glimepiride: Oral 162
... has a leading position within areas such as hemostasis management, growth
hormone therapy and
hormone replacement therapy. Novo Nordisk manufactures and markets pharmaceutical ...
Video: Data on More Than 15 Novartis Oncology Compounds at ASCO Highlight Progress Toward Targeted Therapies for Diverse Tumor Types
... [letrozole tablets] vs. tamoxifen) found that postmenopausal women with
hormone receptor-positive early breast cancer taking adjuvant Femara had better ... octreotide substantially reduces and in many cases can control growth
hormone and/or normalize IGF-1 levels in patients with acromegaly, a disease ...
Melanoma and Pregnancy: What Every Woman Needs to Know About the Risks, Prognosis
... observed the effect of hormones received from external sources -- such as
hormone replacement therapy (HRT) or oral contraceptive pills (OCPs) -- have found ... Cancer followed 206 women diagnosed with localized melanoma who received
hormone replacement therapy within five years of being diagnosed with melanoma. ...
First Candidate from Esperance's Targeted Anti-cancer Platform, EP-100, Establishes Preclinical Proof of Concept
... peptide and is designed to selectively target luteinizing
hormone releasing
hormone (LHRH) receptors, which are overexpressed in a wide range of cancers. ...