History in Medical Technology

Value of Genetic Testing for Preventing Blood Clots Unproven, According to New AHRQ Study

... testing for two gene mutations in adults with a history of blood clots helps to prevent a condition known ... (FVL) and prothrombin G20210A -- as well as a history of deep-vein thrombosis. As many as ... Outcomes of Genetic Testing in Adults with a history of Venous Thromboembolism , is the fifth ...

RISPERDAL(R) CONSTA(R) (Risperidone) Long-Acting Treatment Delayed the Time to Relapse in Patients with Bipolar I Disorder

... risk factors such as being overweight or a family history of diabetes, blood sugar testing should be ... low white blood cell count (WBC) or a history of leukopenia/neutropenia should have frequent ... should be used cautiously in patients with a history of seizures or with conditions that potentially ...

ARVO, AOS: Large Study of Lacrisert(R) Dry Eye Insert;

... ease of use of Lacrisert in adult patients with a history of dry eye syndrome. It was hypothesized that ... a sample subset of 30 contact lens wearers with a history of dry eye. The 30 contact lens patients ... of dry eye in contact lens wearers with a history of dry eye," concluded the ORA investigators. ...

Schering-Plough Announces Results of the Early ACS Trial

... INTEGRILIN is contraindicated in patients with a history of bleeding diathesis, or evidence of active ... major surgery within the preceding six weeks; history of stroke within 30 days, or any history of hemorrhagic stroke; current or planned ...

Overweight Siblings of Children With Type 2 Diabetes Likely to Have Abnormal Blood Sugar Levels

... physical activity, race/ethnicity, family history and insulin resistance. Obesity decreases insulin ... puberty may be enough to unmask disease. Family history is also important; 74-100 percent of children ... Not all children with a family history of type 2 diabetes, insulin resistance or obesity ...

Continuous Treatment With Abbott's HUMIRA(R) Achieves Superior Long-Term Efficacy for Psoriasis Patients Compared to Interrupting Treatment

... arthritis (PsA), or if he or she has a recent history of systemic therapy, including biologic ... o 70 percent of patients with a medical history of PsA * Prior systemic treatment o 78 percent of patients with recent history of systemic biologic treatment ...

Head-to-Head Study Demonstrates Focalin(R) XR Offers Faster and Better Symptom Control than Concerta(R)1 in Early Part of ADHD Patients' Day

... in patients with motor tics or with a family history or diagnosis of Tourette's syndrome; and during ... treatment, patients should have careful history and physical exam to assess for presence ... XR should be given cautiously to patients with a history of drug dependence or alcoholism. Chronic abusive ...

AstraZeneca Submits sNDA for NEXIUM(R) I.V. for Peptic Ulcer Bleed Indication

... (up to 10 days) of GERD adult patients with a history of erosive esophagitis, as an alternative to oral ... (up to 10 days) of GERD adult patients with a history of erosive esophagitis as an alternative to oral ... Injection as a treatment of GERD patients with a history of erosive esophagitis for more than 10 days have ...

CNS Response, Inc. Provides Review of Poster Session Delivered at the American Psychiatric Association 161st Annual Meeting

... also that he had carefully documented treatment history on these patients for two years prior to rEEG ... improvements are challenging as unique patient history and symptom manifestation data is unavailable. ... The long term record of pre-rEEG treatment history compared to post-rEEG treatment makes this ...

Annual FIT Testing Detects Colorectal Cancer Two Years Earlier Than Colonoscopy Alone, Study of High-Risk Population Finds

... in which individuals with a family or personal history of colorectal cancer or adenoma were entered into ... every five years for patients with a family history of colorectal cancer and for patients with a personal history of colorectal cancer who have had a normal 3-year ...

FDA Approves MiddleBrook's Amoxicillin PULSYS for Pharyngitis/Tonsillitis in Adolescents and Adults

... are more likely to occur in individuals with a history of penicillin hypersensitivity and/or a history of sensitivity to multiple allergens. Before ... following antibiotic use. Careful medical history is necessary since CDAD has been reported to ...

AstraZeneca Submits sNDAs for SEROQUEL XR(TM) for the Treatment of Bipolar Mania and Bipolar Depression

... low white blood cell (WBC) count or a history of drug induced leukopenia/neutropenia should ... HS, Schettler PJ, et al. The Long-term Natural history of the Weekly Symptomatic Status of Bipolar I ... al. A Prospective Investigation of the Natural history of the Long-term Weekly Symptomatic Status of ...

European Commission Approves ATRIPLA(R) (efavirenz 600 mg/emtricitabine 200 mg/tenofovir disoproxil fumarate 300 mg), the First Once-Daily Single Tablet Regimen for Virologically Suppressed Adults With HIV-1 Infection

... increase in psychiatric symptoms included a history of injection drug use, psychiatric history, and ... DF. Use ATRIPLA with caution in patients with a history of seizures. Convulsions have been observed in ... generally in the presence of known medical history of seizures. Redistribution/accumulation of ...

Bristol-Myers Squibb and Gilead Sciences Expand Their Alliance to Include Commercialization of ATRIPLA(R) (efavirenz 600 mg/emtricitabine 200 mg/tenofovir disoproxil fumarate 300 mg) in Europe

... increase in psychiatric symptoms included a history of injection drug use, psychiatric history, and ... DF. Use ATRIPLA with caution in patients with a history of seizures. Convulsions have been observed in ... generally in the presence of known medical history of seizures. Redistribution/accumulation of ...

European CHMP Issues Positive Opinion for ATRIPLA(R) (efavirenz 600 mg/ emtricitabine 200 mg/tenofovir disoproxil fumarate 300 mg)

... increase in psychiatric symptoms included a history of injection drug use, psychiatric history, and ... DF. Use ATRIPLA with caution in patients with a history of seizures. Convulsions have been observed in ... generally in the presence of known medical history of seizures. Redistribution/accumulation of body ...

Health Canada Approves ATRIPLA(R) (efavirenz 600 mg/emtricitabine 200 mg/ tenofovir disoproxil fumarate 300 mg), the First Once-Daily Single Tablet Regimen for HIV

... increase in psychiatric symptoms included a history of injection drug use, psychiatric history, and ... DF. Use ATRIPLA with caution in patients with a history of seizures. Convulsions have been observed in ... generally in the presence of known medical history of seizures. Redistribution/accumulation of body ...

New Analyses of Long-Term LIALDA(TM) (mesalamine) Data Presented at ACG

... Irrespective of Patient's Previous Relapse history Poster Presentation: Sunday, October 14, 2007, ... 303 was done to understand the effect of relapse history in patients with mild-to-moderate ulcerative ... in ulcerative colitis patients with a medical history of either a left-sided or extensive condition. Of ...

FDA Approves Lilly's Osteoporosis Drug EVISTA(R) (raloxifene HCl) to Reduce The Risk of Invasive Breast Cancer in Two Populations of Postmenopausal Women

... It emphasizes that women with an active or past history of venous thromboembolism should not take EVISTA ... due to stroke. If you have had a stroke or have a history of other significant risk factors for stroke, ... (TIA/transient ischemic attack), hypertension, history of cigarette smoking or a type of irregular ...

PNH Patients Treated with Soliris(TM) Experienced Dramatic Reduction in Blood Clots During Clinical Trials

... group of PNH patients, including those without a history of blood transfusion, found that 60 percent had ... SM, Bessler M, Luzzatto L, Dacie JV. Natural history of paroxysmal nocturnal hemoglobinuria. N ... VM, Mukhina GL, Garrett ES, Brodsky RA. Natural history of paroxysmal nocturnal haemoglobinuria ...

Video: FDA Approves INVEGA(R) SUSTENNA(TM) for the Acute and Maintenance Treatment of Schizophrenia

... have diabetes or have risk factors such as being overweight or a family history of diabetes, blood sugar testing should be done at the beginning and ... decreases in the counts of white cells in circulating blood. If you have a history of low white blood cell counts or have unexplained fever or infection, ...

Music & Medicine: Unique Collaboration Combines Performing Arts and Science

... problems. We've partnered to look at this. Hopefully we'll have a long history together." This dual-campus project has since grown, though, to ... what Dr. Chesky had to fit our needs," she said. "Because we both have history with him, we're rolling him into this project, and he will be included in ...

Study Reported Tadalafil Taken Once Daily Improved Erectile Function in Men with ED and Sexual Quality of Life in Couples

... multicenter, randomized study followed 342 men with a minimum three-month history of ED, as well as their female partners who had adequate sexual function ... a result of other primary sexual disorders or related surgeries; 3) had a history of other medical conditions or treatments that could negatively impact ...

Genetic Source of Rare Childhood Cancer Found; Gene is Implicated in Other Cancers

... expression of other genes. The children studied came from families with a history of PPB or related disorders. "PPB is the first malignancy found to be ... studies show around 40 percent of PPB cases occur in families with a history of the disease or certain other childhood cancers. In contrast, most ...

Heavy Marijuana Use May Damage Developing Brain in Teens, Young Adults

... Center. The 14 subjects from the drug treatment center all had a history of heavy cannabis use during adolescence. On average, they had smoked ... sample size, five of the 14 subjects with heavy cannabis use also had a history of alcohol abuse, which may have contributed an effect. Also, it is ...

AAOMS Updates BRONJ Position Paper

... the maxillofacial region for more than eight weeks; and 3. There is no history of radiation therapy to the jaws. While there is strong evidence ... that may increase the risk of developing BRONJ include: A history of inflammatory dental disease, such as periodontal disease and dental ...

Study Finds DOXIL(R) Combination Therapy Delays Disease Progression for Patients With Metastatic Breast Cancer

... HCl on a mg per mg basis Contraindications * Patients with a history of hypersensitivity reactions to a conventional doxorubicin ... discontinuation of anthracycline therapy - For patients with a history of cardiovascular disease, or if the results of cardiac ...

Video: Tasigna(R) Demonstrates Rapid Response as Initial Therapy in Life-Threatening Form of Leukemia

... Elevated serum lipase Caution is recommended in patients with history of pancreatitis. Check serum lipase periodically. Liver function ... and risk factors, including advanced age and previous medical history of cardiac disease. Patients with cardiac disease or risk factors for ...

Alexion Reports Positive Results from AEGIS Registration Study of Soliris in Japanese Patients With PNH

... or equal to 30x10(9)/L). Forty-five percent of the AEGIS patients had a history of aplastic anemia or myelodysplastic syndromes. Patients were dosed in ... Hillmen P, Lewis SM, Bessler M, Luzzatto L, Dacie JV. Natural history of paroxysmal nocturnal hemoglobinuria. N Engl J Med. 1995; ...

Observational Study Finds Changes in Medicare Reimbursement for Erythropoiesis-Stimulating Agents Associated With Increased Need for Blood Transfusion

... of PROCRIT therapy have not been established in patients with a known history of a seizure disorder or underlying hematologic disease (e.g., sickle cell ... and aggressively managed, particularly in patients with an underlying history of hypertension or cardiovascular disease. In studies, the most ...

More Than 200 Abstracts at ASH and SABCS Reveal Potential Compelling Patient Benefits From Novartis Oncology Current and Pipeline Therapies

... and risk factors, including advanced age and previous medical history of cardiac disease. Patients with cardiac disease or risk factors for ... Elevated serum lipase Caution is recommended in patients with history of pancreatitis. Check serum lipase periodically. Liver function ...

American Lung Association Celebrates 101st Annual Christmas Seals Campaign

... this concept for over one hundred years. "While we have a rich history with our Christmas Seals and the fight against tuberculosis, the Lung ... urges people to visit www.christmasseals.org to learn more about the history of Christmas Seals, to view past Christmas Seals, to make a donation or to ...

Study Showed Prevention of Heart Attacks Within Three Months After Hospitalization Significantly Averted Future Heart Attacks and Death

... in age (median of 62 vs. 63), female sex (36 percent vs. 33 percent), history of hypertension (69 percent vs. 68 percent), history of diabetes (36 percent vs. 30 percent) and multi-vessel coronary artery ...

Data From Investigational Use of PROCRIT(R) (Epoetin alfa) Presented at American Society of Nephrology Annual Meeting

... of PROCRIT therapy have not been established in patients with a known history of a seizure disorder or underlying hematologic disease (e.g., sickle ... aggressively managed, particularly in patients with an underlying history of hypertension or cardiovascular disease. -- In studies, the most ...

Bavarian Nordic Reports Successful Safety Data From Phase II Study With IMVAMUNE(R)

... from over 300 HIV infected and 86 healthy subjects, all of whom had no history of prior smallpox vaccination. The low number of adverse events confirmed ... study arm funded by the NIH under RFP-2 (HIV infected subjects with a history of previous exposure to a conventional smallpox vaccine). This ...

CIMZIA(R) (Certolizumab Pegol) Provides Rapid and Sustained Relief from Signs and Symptoms of Rheumatoid Arthritis for Two Years

... therapy prior to initiation of CIMZIA in patients with a past history of latent or active tuberculosis in whom an adequate course of treatment ... Exercise caution when considering the use of CIMZIA in patients with a history of recurrent infection, concomitant immunosuppressive therapy, or ...

CIMZIA(R) (Certolizumab Pegol) Provides Long-Term Benefit Without Dose Escalation in Crohn's Disease Patients

... therapy prior to initiation of CIMZIA in patients with a past history of latent or active tuberculosis in whom an adequate course of treatment ... Exercise caution when considering the use of CIMZIA in patients with a history of recurrent infection, concomitant immunosuppressive therapy, or ...

New Findings Show Efficacy of REMICADE(R) Compared With Azathioprine in Treatment of Crohn's Disease According to First-of-its Kind Study

... enrolled in SONIC had extra-intestinal manifestations, 18 percent had a history of fistulas, 21 percent had bowel resections, 27 percent had been ... lower your ability to fight infections, so if you are prone to or have a history of infections, or develop any signs of an infection such as fever, ...

CIMZIA(R) (certolizumab pegol) Reduces Intestinal Lesions and Induces Endoscopic Improvement in Crohn's Patients

... therapy prior to initiation of CIMZIA in patients with a past history of latent or active tuberculosis in whom an adequate course of treatment ... Exercise caution when considering the use of CIMZIA in patients with a history of recurrent infection, concomitant immunosuppressive therapy, or ...

New Analyses Indicate that Divigel(R) (estradiol gel) 0.1% Is a Valuable Option for Certain Postmenopausal Women With Hot Flashes

... in women with undiagnosed abnormal vaginal bleeding; known, suspected, or history of breast cancer; known or suspected estrogen-dependent neoplasia; active or history of deep vein thrombosis (DVT) or pulmonary embolism; active or recent ...

Merck Serono Announces Initiation of the ORACLE MS Trial to Evaluate Cladribine Tablets in Patients at Risk of Developing Multiple Sclerosis

... micrograms). Rebif(R) should be used with caution in patients with a history of depression, liver disease and seizures. Most commonly reported side ... and chemical company with total revenues of EUR 7.1 billion in 2007, a history that began in 1668, and a future shaped by 31,946 employees in 60 ...