Debiopharm Group and Mercury Therapeutics, Inc. Sign an Exclusive License Agreement for the Development and Commercialisation of Debio 0930
... of AMPK has
been shown to lower fasting blood
glucose levels and improve
glucose disposal
following a
glucose challenge, two key goals in the management of ...
Exenatide Once Weekly Provided Superior Glucose Control Compared to Lantus(R) in Head-to-Head DURATION-3 Study
... weekly experienced a greater reduction in blood
glucose than those treated with Lantus, they also ... type 2 diabetes who were not achieving adequate
glucose control using metformin therapy alone or in ... in body weight along with other parameters of
glucose control, cardiovascular health, hypoglycemia and ...
Reliv International's GlucAffect(TM) Proven Effective in Clinical Study
... Study Shows GlucAffect Reduces Blood
glucose Levels and Promotes Weight Loss
... (Nasdaq: RELV ), significantly reduced blood
glucose levels and helped control weight in study ... 50 overweight individuals who had pre-diabetic
glucose levels prior to the study. Subjects taking ...
Number of Patients With Dementia on the Rise
... substances by the brain. Normally, the brain uses
glucose as a fuel. Using PET scans, doctors can image the amount of
glucose used by the brain to determine whether there's a ... medications that treat Alzheimer's. Studies with
glucose are being supplemented by PET scans that can ...
Spherix Announces Positive Phase 2 Study Results
... type 2 diabetes underwent separate 3-hour oral
glucose and tagatose tolerance tests. The subjects were ... (75 g) caused no increase in plasma insulin or
glucose concentrations in either healthy or diabetic ... potato load, and a 2 x 3 factorial design for a
glucose load in which each subject participated in 11 ...
FDA Advisory Committee Votes in Favor of Zyprexa for Two Adolescent Indications
... between atypical antipsychotics and increases in
glucose levels appears to fall on a continuum and Zyprexa ... mellitus, or having borderline increased blood
glucose level. Patients taking Zyprexa should be monitored regularly for worsening of
glucose control. Patients starting treatment with ...
Isis Highlights New Data on Antisense Drugs to Treat Type 2 Diabetes and Obesity at ADA Scientific Sessions
... and sustained reduction in sodium dependent
glucose co-transporter type 2 (SGLT2) levels that resulted in a significant reduction in blood
glucose levels in multiple animal species. Isis and its ... antisense drugs can significantly lower blood
glucose levels and increase the body's sensitivity to ...
Tolerx Presents Data at 69th Scientific Sessions of the American Diabetes Association
... the body has difficulty regulating its blood
glucose (sugar) level. There are two major types of ... insulin production, patients must monitor their
glucose levels frequently and administer insulin regularly to control their blood
glucose levels.
About Otelixizumab
...
Exenatide Once Weekly Provided Sustained Improvements in Glycemic Control With Weight Loss Over Two Years: DURATION-1 Interim Long-Term Data Presented at ADA 2009
... from the DURATION-1 study that showed sustained
glucose control with weight loss, as well as improvements ... in A1C of 1.7 percent and fasting plasma
glucose (FPG) of 40 mg/dL were maintained after two years ... A1C of less than 7 percent is the target for good
glucose control as recommended by the ADA. Body weight ...
Studies Show AFRESA(R) Controls Post-Meal Sugar Levels With Less Weight Gain and Hypoglycemia Risk for Diabetes Patients
... type 2 diabetes, as it controls post meal-time
glucose levels with the added benefits of less weight ... and treatment differences in postprandial plasma
glucose (PPG), fasting plasma
glucose (FPG), and weight.
A1C was reduced by -0.66% ...
New Study Showed Lantus(R) Plus One, Two or Three Shots of Apidra(R) Lowered Patients' Blood Sugar
... adjusted to achieve an A1C<7%, fasting plasma
glucose (FPG) and preprandial blood
glucose < 110 mg/dl, and bedtime blood
glucose < 130 mg/dl. FPG, Lantus(R) dose, and weight ...
Boehringer Ingelheim Unveils Diabetes Pipeline
... Ingelheim is also investigating sodium-dependent
glucose co-transporter-2 inhibitors (SGLT-2 inhibitors), ... compounds that block tubular reabsorption of
glucose in the kidney.(4) Phase IIb clinical trials for ... HbA1c and fasting blood sugar or fasting plasma
glucose (FPG) levels (p-values of less than 0.05%):(1) ...
AFRESA(R) Phase 3 Pulmonary Function Safety Data in Patients with Diabetes Presented at ADA
... while accepted as an effective means to control
glucose levels, have several limitations," said Peter ... by the pancreas, normally regulates the body's
glucose levels, but in people with diabetes insufficient ... likelihood of weight gain, inadequate post-meal
glucose control, the need for complex titration of ...
Metabolic Solutions Development Company Announces Preliminary Results from Phase IIa Clinical Trial
... show improved insulin sensitivity and lower
glucose levels
without the side effects of current ... can improve insulin sensitivity and lower blood
glucose levels in humans without the side effects of ... (TZD) can improve insulin sensitivity and lower
glucose similar to a traditional TZD," said Dr. Jerry ...
Diabetes Experts Issue New Recommendations for Inpatient Glycemic Control - Call for Systemic Changes in Hospitals Nationwide
... treat hospitalized patients with high blood
glucose (sugar) levels. The authors recommend revised
glucose targets of 140-180 mg/dL in the ICU setting, and ... at a time when attempts to intensively manage
glucose targets in the ICU setting have shown ...
Joint Statement from the American Diabetes Association and American Association of Clinical Endocrinologists on the NICE-SUGAR Study on Intensive Versus Conventional Glucose Control in Critically Ill Patients
... of Medicine suggests that intensive blood
glucose (sugar) control for critical care patients with ... in Intensive Care Evaluation-Survival Using
glucose Algorithm Regulation (NICE-SUGAR) study should NOT lead to an abandonment of the concept of good
glucose management in the hospital setting. Uncontrolled ...
Genaera Presents Preliminary Phase 1b Data for Trodusquemine (MSI-1436)
...
A 9.5% decrease in fasting blood
glucose with a resulting 17% differential compared to ... in the area under the curve during the oral
glucose tolerance test;
An 11.3% decrease in ... early indicators of weight loss and improved
glucose control. These results confirm previous work in ...
Genaera Presents Promising Preclinical Data for Trodusquemine (MSI-1436) at Keystone Symposia
... in body weight, as well as marked improvements in
glucose tolerance and lipid profile.
"The DIO rat is ... early indicators of weight loss and improved
glucose control. These results confirm previous work in ... associated with obesity such as abnormal
glucose metabolism and cholesterol elevation.
...
FDA Issues a Complete Response Letter for Lilly's Olanzapine LAI for Treatment of Schizophrenia in Adults
... atypical antipsychotics and increases in
glucose levels appears to
fall on a continuum and ... mellitus, or having borderline increased blood
glucose level.
Patients taking olanzapine should be ... should be
monitored regularly for worsening of
glucose control; those with risk factors
for diabetes ...
Arena Pharmaceuticals Announces Initiation of Phase 1 Clinical Trial of Type 2 Diabetes Drug Candidate in Partnership with Ortho-McNeil-Janssen Pharmaceuticals
... by beta cells in response to elevated blood
glucose levels. In addition, the GDIR is expressed in ... play an important role in insulin regulation and
glucose homeostasis. GDIR stimulation has also been found ... or inadequate secretion of insulin as blood
glucose levels rise. Therapies for type 2 diabetes are ...
Overweight Siblings of Children With Type 2 Diabetes Likely to Have Abnormal Blood Sugar Levels
... are four times more likely to have abnormal
glucose levels compared to other overweight children. Because abnormal
glucose levels may indicate risk for diabetes or diabetes ... not specifically looked at the risk of abnormal
glucose tolerance among siblings of children diagnosed ...
Study Shows ACCU-CHEK(R) Blood Glucose Monitoring Systems and Lancing Devices Are Least Painful
... pain and
discomfort associated with blood
glucose testing showed ACCU-CHEK blood
glucose monitoring ... ACCU-CHEK Aviva and ACCU-CHEK Compact
Plus blood
glucose monitoring systems and the ACCU-CHEK Multiclix, ... and effective diabetes management-from
blood
glucose monitoring through information management to ...
FDA Approves Rapid-Acting Insulin Apidra(R) for Treatment of Children with Diabetes
... control, as assessed by the
self-monitored blood
glucose values and blood
glucose excursions, was
similar in both treatment groups ... other medicines and supplements you
are taking.
glucose monitoring is recommended for all patients ...
Genaera Corporation Reports Phase 1 Data for Trodusquemine (MSI-1436) at the North American Association for the Study of Obesity Annual Meeting
... both the leptin and insulin pathways to normalize
glucose and decrease
appetite. In the study, MSI-1436 was ... multiple dose PK and secondary
outcomes of oral
glucose tolerance and insulin sensitivity, satiety ... associated
with obesity such as abnormal
glucose metabolism and cholesterol elevation.
About ...
Mayo Clinic Discovery May Help Diabetic Gastric Problem
... becomes
unpredictable, maintaining a proper blood
glucose level -- critical for
controlling diabetes -- ... of nutrients. The abnormally high blood
glucose levels cause
chemical changes in nerves and in ... therefore improve a patient's quality of
life and
glucose control."
Science Behind the Findings
...
Takeda Submits a New Drug Application in the U.S. for Alogliptin (SYR-322) / ACTOS(R) (pioglitazone HCl) for the Treatment of Type 2 Diabetes
... incretins play
a major role in regulating blood
glucose levels and have the potential to
improve ... tract in response to food and regulate
glucose balance, primarily
by stimulating ... and subsequent liver glucose
production, enhances
glucose disposal, slows gastric emptying, and ...
MannKind Reports Positive Data from a Phase 3 Clinical Study of Technosphere Insulin in Type 1 Diabetes
... pre-defined A1C goals * Superior fasting blood
glucose levels * Better early post-prandial
glucose control * Fewer patients experiencing ... including its positive effects on fasting
glucose levels.
Technosphere Insulin promises to be an ...
Novo Nordisk New Data From a Phase 3 Study Confirms Clinical Benefits of Once-Daily Liraglutide in the Management of Type 2 Diabetes
... of type 2 diabetes, leads to improved blood
glucose lowering
(HbA1c), weight loss, blood pressure ... of 1.5% from baseline HbA1c.
Fasting blood
glucose levels decreased by 2.4 mmol/L within two weeks ... significant.
In addition to improved
glucose lowering, liraglutide treatment also
led to ...
Olanzapine Long-Acting Injection (LAI) Shown to Maintain Treatment Benefit in Schizophrenia for up to Six Months
... factors for diabetes mellitus for which regular
glucose control
is recommended.
Undesirable alterations ... of
therapy, the rate of increase in mean blood
glucose slowed after
approximately 4-6 months.
As with ... eosinophilia, elevated
prolactin, cholesterol,
glucose and triglyceride levels, glucosuria,
increased ...
Nature Publication Reports on Key Role of Bile Acids in Glucose Metabolism and Insulin Signaling
... acting as important mediators of
glucose metabolism and insulin
signaling. The featured ... gain.
-- Bile acids have broad effects on
glucose homeostasis, including a
decrease in ... Additionally, mice
that lack FXR have impaired
glucose tolerance and are insulin-resistant.
Dr. ...
Tolerx Initiates Dosing of Otelixizumab, a Novel Type 1 Diabetes Agent, in DEFEND, a Phase 3 Clinical Trial
... of
administered insulin required to control blood
glucose levels by inhibiting
the destruction of beta ... production means
that patients must monitor their
glucose levels frequently and take insulin
regularly to control their blood
glucose levels.
About Otelixizumab
Otelixizumab is a ...
Echo Therapeutics Announces Positive Results of a Clinical Study of its Symphony(TM) Transdermal Continuous Glucose Monitoring System in Patients with Type 1 and Type 2 Diabetes
... of its Symphony(TM) Transdermal Continuous
glucose Monitoring (tCGM)
System in patients with Type 1 ... and easy-to-use,
needle-free continuous
glucose monitoring device.
"This study represents ... is safe, accurate and reliable at monitoring
glucose levels.
We look forward to continuing progress ...
Newly Published Study Results Showed That Two Mealtime Insulin Dosing Algorithms Were Effective for Patients with Type 2 Diabetes
... significant reductions
in postprandial blood
glucose and A1C using two different dosing
algorithms.
... based on the previous week's self-monitored
blood
glucose (SMBG) results. One group, the "Simplified ... bolus insulin may be needed to achieve
optimal
glucose control in type 2 diabetes patients," explained ...
'Snapshots' of Eyes Could Serve as Early Warning of Diabetes or Diabetic Eye Disease, U-M Researchers Report
... potentially significant advantages over blood
glucose testing, the
"gold standard" for diabetes ... Petty also observes that unlike
glucose monitoring, elevation of FA
levels reflects ... abnormally high FA would be
prompted to undergo
glucose tolerance testing," says Elner. "If the
findings ...
Echo Therapeutics Announces Publication of Positive Clinical Data for its Symphony Transdermal Continuous Glucose Monitoring System in Journal of Diabetes Science and Technology
... for reliable, non-invasive, real-time continuous
glucose monitoring,
and its most recently developed skin ... "Tight glycemic control through continuous
glucose monitoring is
essential for patients in diverse ... Study Design
Transdermal continuous
glucose monitors were applied to patients with
diabetes ...
Echo Therapeutics Initiates Clinical Study of Its Symphony(TM) Transdermal Continuous Glucose Monitoring System in Patients with Type 1 and Type 2 Diabetes
... affordable and
comfortable-to-wear continuous
glucose monitoring device.
"Building on the momentum ... to generate painless, needle-free, continuous
glucose measurements.
The primary purpose of this new ... System with both the "gold standard" YSI
glucose Analyzer and a
widely-used, commercially ...
Olanzapine Long-Acting Injection (LAI) Data Presented at First Annual Schizophrenia International Research Society Conference
... The percentage of patients with a fasting
glucose increase from normal
to high at any time was 4.7 ... between atypical antipsychotics
and increases in
glucose levels appears to fall on a continuum ... mellitus, or who have borderline increased blood
glucose level.
Patients taking olanzapine should be ...
Video: Clinical Study Shows Liraglutide Reduced Blood Sugar, Weight, and Blood Pressure in Patients with Type 2 Diabetes
... and systolic blood pressure, but sustained
blood
glucose reductions for the duration of the study in ... liraglutide provided
substantial improvement in
glucose control from baseline and statistically
significantly better
glucose control than glimepiride. Patients ...
Isis Highlights Robust Drug Portfolio for Diabetes and Obesity at ADA Conference
... - Oral presentation on the potent blood
glucose lowering effect of SGLT2 antisense ... drugs potently reduce levels
of sodium dependent
glucose transporter type 2 (SGLT2), a key component in
controlling
glucose re-absorption in the kidney and the target of ...
After One Year, Type 2 Diabetes Patients Taking Exenatide Once Weekly Sustained Improvements in Glycemic Control and Weight; DURATION-1 Presented at ADA 2008
... Investigational Diabetes Therapy Also Improved
glucose Control in Patients Switching from Exenatide ... control [A1C: -2.0%+/-0.08; fasting plasma
glucose (FPG) -47+/-3
mg/dL] compared to those receiving ... that requires constant management of
blood
glucose or blood sugar as well as weight. In DURATION-1 ...