Generalized in Medical Technology

Interleukin Genetics to Present Important New Findings at 2008 World Congress on Osteoarthritis

... titled "Genetic Markers Associated with generalized Osteoarthritis," will be presented during the ... more likely to develop OA in their hands, a more generalized form of the disease that adds further ... to compromised physical activity and more generalized disease affecting the hands. Severe structural ...

European CHMP Issues Positive Opinion on Cymbalta for the Treatment of Generalised Anxiety Disorder

... and remission. Patients report that episodes of generalized anxiety disorder are often brought on, or ... incontinence, Major Depressive Disorder and generalized Anxiety Disorder. Duloxetine is approved only for ... and Safety of Duloxetine in the Treatment of generalized Anxiety Disorder: A Flexible-Dose, ...

AstraZeneca Submits sNDA for SEROQUEL XR(TM) for the Treatment of Generalized Anxiety Disorder - a First for the Atypical Antipsychotic Class of Medicines

... Tablets to seek approval for the treatment of generalized anxiety disorder (GAD), including maintenance ... Boxed Warnings, for SEROQUEL XR. About generalized Anxiety Disorder (GAD) GAD is characterized by ... 3. Rickels K and Ryann M. Pharmacotherapy of generalized Anxiety Disorder. J Clin Psychiatry. 2002;63 ...

New Data on SEROQUEL XR(TM) in Treatment of Both Major Depressive Disorder and Generalized Anxiety Disorder Presented at APA Annual Meeting

... treatment of major depressive disorder (MDD) and generalized anxiety disorder (GAD) in adult patients. The ... "Given that many people suffering from generalized anxiety disorder do not achieve an adequate ... can lead to suicide.(6) About generalized Anxiety Disorder GAD is characterized by ...

Keppra XR(TM) Extended-Release Tablets Filed with the FDA

... with juvenile myoclonic epilepsy, and primary generalized tonic-clonic seizures in adults and children 6 years of age and older with idiopathic generalized epilepsy. Keppra(R) injection is indicated as ... 6 years of age and older with idiopathic generalized epilepsy, the most common adverse event ...

UCB Announces Positive Phase III Trial Results for Keppra XR(TM) (levetiracetam) Extended-Release Tablets

... with juvenile myoclonic epilepsy, and primary generalized tonic-clonic seizures in adults and children 6 years of age and older with idiopathic generalized epilepsy. Keppra(R) injection is indicated as ... 6 years of age and older with idiopathic generalized epilepsy, the most common adverse event ...

New Data Published in Neurology Show Once-Daily Lamictal XR Significantly Reduced Partial Seizures in Patients with Epilepsy

... a restricted area of the brain. Secondarily generalized seizures start out affecting only one side of the ... from baseline in weekly frequency of secondarily generalized seizures was also significantly higher in ... electrical disturbance that produces seizures. generalized seizures are seizures that involve the entire ...

March 2009 Mayo Clinic Health Letter Highlights Knee Repair Surgery, Anxiety Disorder and Preventing Blood Clots

... activities, it's time to see a doctor. Overwhelming worry is a symptom of generalized anxiety disorder (GAD). The March issue of Mayo Clinic Health Letter covers the symptoms of GAD and treatment options. With generalized anxiety disorder, shedding worries is difficult, even when the worry is ...

Forest Laboratories, Inc. Announces Positive Results of LEXAPRO(R) Phase III Study in Adolescents With Major Depression

... for the initial and maintenance treatment of major depressive disorder and generalized anxiety disorder (GAD) in adults. LEXAPRO is thought to work by helping to ... for the initial and maintenance treatment of major depressive disorder and generalized anxiety disorder; Namenda(R) (memantine HCl), an N-methyl D- aspartate ...

SCAI Statement on the BARI 2D Trial (Bypass Angioplasty Revascularization Investigation With Diabetes Trial) Presented at the American Diabetes Association (ADA) Annual Scientific Sessions and Published in The New England Journal of Medicine

... "healthier" patients as studied in BARI-2D. The trial's findings - while important - apply only to a narrow group of patients, and should not be generalized across broad groups of cardiovascular patients. As always, SCAI emphasizes each patient must be assessed individually based on his or her unique ...

VIVUS Initiates Open Label Safety Study of Avanafil for Erectile Dysfunction

... it has completed enrollment in REVIVE (TA-301), a randomized, double-blind, placebo-controlled phase 3 study of avanafil in men with a history of generalized ED and the first of several planned phase 3 studies of avanafil. Approximately 650 patients have been enrolled in the study. Top-line results of ...

Brain Training Improves Memory and Attention and the Effects Last

... Dr. Zelinski, PhD. "From a researcher's point of view, this was very impressive because people got better at the tasks trained, those improvements generalized to standardized measures of memory and people noticed improvements in their lives. What this means is that cognitive decline is no longer an ...

New Imaging Analysis Predicts Brain Tumor Survival

... the changes as an average. Results of the study appear in the advance online edition of Nature Medicine . "What we have potentially is a generalized analytical approach that we can use to quantify treatment intervention in patients," says study author Brian Ross, Ph.D., professor of radiology and ...

CSL Behring Receives Orphan-Drug Exclusivity for RiaSTAP(TM), First and Only Approved Treatment of Acute Bleeding Episodes in Patients with Congenital Fibrinogen Deficiency

... reactions that have been reported in clinical studies or through postmarketing surveillance following RiaSTAP treatment are allergic reactions and generalized reactions such as chills, fever, nausea and vomiting. For more information, visit www.riastap.com . About CSL Behring CSL Behring is a ...

Evidence Lacking in Multivitamin Study of Women's Risk of Cancer, Heart Disease or Death, Says Natural Products Association

... factors such as nutrients gained through diet." Fabricant said it is "unprincipled" that the authors arbitrarily lumped supplement types into generalized categories that do not represent nutrient intake accurately. And when coupled with the fact that nutrient intake through the diet was not accounted ...

Retigabine Significantly Reduces the Number of Seizures in Adults With Inadequately Controlled Partial-Onset Epilepsy

... disturbance in the brain. The kind of seizure a person has depends on which part and how much of the brain is affected by the disturbance. Primary generalized seizures involve the entire brain from the outset, while partial-onset seizures begin in a focal area of the cerebral cortex. In most cases, however, ...

Stress-Related Disorders Affect Brain's Processing of Memory

... cortex to the hippocampus, while study participants performed a memory task. Participants included 11 patients with major depression, 13 with generalized anxiety disorder, nine with panic attack disorders, five with borderline personality disorder and 21 healthy individuals. All patients reported ...

Enobia Initiates Infantile Enzyme Replacement Trial for Rare Bone Disease

... in the first six months of life. These can include failure to thrive, respiratory failure, fractures, and seizures. Radiographic findings include generalized hypomineralization and rickets. Mortality in these patients may be as high as 50%. In the childhood form, patients have varying degrees of ...

Lilly Withdraws Application for Additional U.S. Indication for Cymbalta(R) for Chronic Pain

... chronic osteoarthritis pain of the knee. The decision does not affect duloxetine's FDA-approved indications for major depressive disorder, generalized anxiety disorder, management of diabetic peripheral neuropathic pain and management of fibromyalgia. Lilly submitted the chronic pain ...

FDA Approves Rapid-Acting Insulin Apidra(R) for Treatment of Children with Diabetes

... fat tissue at the injection site; and allergic reactions, such as itching and rash. Less common, but potentially more serious or life-threatening, is generalized allergy to insulin, including anaphylactic reactions. When used in a pump, do not mix Apidra(R) with any other insulin or liquid. If the pump or ...

Indevus Announces Agreement With Teva to Develop Pagoclone for the Treatment of Stuttering

... selective GABA-A receptor agonist. In clinical studies in anxiety disorders, it has been shown to reduce the symptoms of panic disorder and generalized anxiety disorder without causing the sedation or withdrawal effects seen with benzodiazepine agents. Pagoclone trials have enrolled over 1,500 ...

Enobia Pharma Appoints Industry Veterans with Commercial and Manufacturing Expertise to Expand Senior Management Team

... in the first six months of life. These can include failure to thrive, respiratory failure, fractures, and seizures. Radiographic findings include generalized hypomineralization and rickets. Mortality in these patients may be as high as 50%. In the childhood form, patients have varying degrees of ...

Enobia Pharma Receives FDA Orphan Drug Designation for Hypophosphatasia Product Candidate ENB-0040

... in the first six months of life. These can include failure to thrive, respiratory failure, fractures, and seizures. Radiographic findings include generalized hypomineralization and rickets. Mortality in these patients may be as high as 50%. In the childhood form, patients have varying degrees of ...

F.D.A. Approves SANCUSO(R), the First and Only Patch for Preventing Nausea and Vomiting in Cancer Patients Undergoing Chemotherapy

... and/or gastric distention caused by the underlying condition. Mild application site reactions have occurred; remove patch if severe reactions or a generalized skin reaction occur. Patients should avoid direct exposure of application site to natural or artificial sunlight by covering with clothing while ...

Enobia Pharma Initiates Clinical Testing of Enzyme Replacement Therapy to Treat Hypophosphatasia

... in the first six months of life. These can include failure to thrive, respiratory failure, fractures, and seizures. Radiographic findings include generalized hypomineralization and rickets. Mortality in these patients may be as high as 50%. In the childhood form, patients have varying degrees of ...

MonoSol Rx Completes Thin Film Escitalopram Oxalate Pilot Product Development

... for its thin film formulation of escitalopram oxalate, a selective serotonin reuptake inhibitor. Escitalopram oxalate is indicated for depression and generalized anxiety disorders and is marketed under the brand name Lexapro(R). Lexapro generated sales of $2.1 billion in 2007. Based on product development ...

New AVAC Report on Pre-Exposure Prophylaxis Calls for Immediate Planning to Anticipate Study Results of Potential New HIV Prevention Option

... settings and populations for PrEP use, determining what level of efficacy would warrant widespread delivery and determining where targeted vs. more generalized delivery would be more appropriate. 4. Prepare for global procurement and delivery of PrEP: Plans for PrEP delivery must include a well-planned and ...

FDA Grants Pediatric Exclusivity for TOPAMAX(R), Extending the Marketing Exclusivity by Six Months

... patients aged 1 to 24 months. TOPAMAX(R) is indicated as initial monotherapy in patients 10 years of age and older with partial onset seizures or generalized tonic-clonic seizures. It also is indicated as adjunctive therapy for adults and children (aged two and above) with partial onset seizures or ...

Long-Term Followup in Phase 3 CLL Trial Shows Genasense(R) is Associated with Significantly Increased Survival in All Responders

... and serves important immune functions. Patients with CLL typically develop symptoms that may progress over a period of years, ultimately producing a generalized depression of immunity, marked increases in the size of spleen, liver and lymph nodes, and impaired production of other normal blood cells. ...

Data Show Rufinamide, an Investigational Adjunctive Treatment for Lennox- Gastaut Syndrome, Reduced Drop Attacks by More Than 40%

... placebo (increase of 1.4%). The differences between rufinamide and placebo were observed as early as week two of the study. LGS is a severe form of generalized epilepsy that develops in early childhood and is characterized by multiple types of treatment-resistant seizures and high rates of seizure-related ...

CryoLife Announces First Implant of Combination Aortic-Mitral Allograft Heart Valve at the Cleveland Clinic

... the structures of the heart, particularly the heart valves, contain some type of infection. This infection can be localized within the heart, or generalized throughout the body. Blood clots can form as a result of this infection. Valve dysfunction is common and can involve the aortic, mitral or tricuspid ...

Study Demonstrates Lexapro(R) Significantly Improves Depression Symptoms in Adolescents

... studied as a treatment for adolescents with MDD. Lexapro is indicated for the initial and maintenance treatment of major depressive disorder and generalized anxiety disorder (GAD) in adults. Lexapro is thought to work by helping to restore the brain's chemical balance. It is believed to increase the ...

Elite Team of Cyclists with Type 1 Diabetes Powers Forward in 2008 Sponsored by Rapid-Acting Insulin Apidra(R)

... fat tissue at the injection site; and allergic reactions, such as itching and rash. Less common, but potentially more serious or life-threatening, is generalized allergy to insulin, including anaphylactic reactions. When used in a pump, do not mix Apidra(R) with any other insulin or liquid. If the pump or ...

FDA Indicates That Genasense(R) Approval in Chronic Lymphocytic Leukemia Will Require Additional Confirmatory Data

... and serves important immune functions. Patients with CLL typically develop symptoms that may progress over a period of years, ultimately producing a generalized depression of immunity, marked increases in the size of spleen, liver and lymph nodes, and impaired production of other normal blood cells. ...

Microbia and Forest Laboratories Announce Preliminary Results of Linaclotide Phase 2b Studies

... includes Lexapro(R) (escitalopram oxalate), an SSRI indicated for adults for the initial and maintenance treatment of major depressive disorder and generalized anxiety disorder; Namenda(R) (memantine HCl), an N-methyl D-aspartate (NMDA)-receptor antagonist indicated for the treatment of moderate to severe ...

Neuroscientists Offer Hope for Breast Cancer Patients Suffering From 'Chemobrain'

... had statistically significant improvements in cognitive function, stress levels and health-related quality of life, suggesting that the benefits generalized into every day life. "When I began the training, I couldn't remember appointments, where I put things and I had trouble finding the right word," ...

Genasense Plus Chemotherapy Is Associated With Prolonged Survival in Patients With Relapsed/Refractory CLL Who Achieve Complete Remission

... and serves important immune functions. Patients with CLL typically develop symptoms that may progress over a period of years, ultimately producing a generalized depression of immunity, marked increases in the size of spleen, liver and lymph nodes, and impaired production of other normal blood cells. ...

Milnacipran Demonstrated Significant Improvement in Pain and the Core Symptoms of Fibromyalgia Syndrome, Data Show

... includes Lexapro(R) (escitalopram oxalate), an SSRI indicated for adults for the initial and maintenance treatment of major depressive disorder and generalized anxiety disorder; Namenda(R) (memantine HCl), an N-methyl D- aspartate (NMDA)-receptor antagonist indicated for the treatment of moderate to severe ...

Forest Laboratories, Inc. and Gedeon Richter Announce Results of Phase II-B Study for RGH-188 as a Treatment for Schizophrenia

... includes Lexapro(R) (escitalopram oxalate), an SSRI indicated for adults for the initial and maintenance treatment of major depressive disorder and generalized anxiety disorder; Namenda(R) (memantine HCl), an N-methyl D-aspartate (NMDA)-receptor antagonist indicated for the treatment of moderate to severe ...

Daiichi Sankyo and Forest Laboratories Finalize Contract for Co-Promotion of AZOR(TM)

... includes Lexapro(R) (escitalopram oxalate), an SSRI indicated for adults for the initial and maintenance treatment of major depressive disorder and generalized anxiety disorder; Namenda(R) (memantine HCl), an N-methyl D-aspartate (NMDA)-receptor antagonist indicated for the treatment of moderate to severe ...