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Gene Therapy Eradicates Pancreatic Cancer in Preclinical Trial Targeting System's Success in Mouse Model Reported in Cancer Cell

... known to kill cancercells. It's all packaged in a fatty ball called a liposome anddelivered intravenously. Researchers are working with M. D. Anderson clinicians to movethe system, developed and tested in mouse models of pancreaticcancer, to a Phase I clinical trial. "This looks like a promising appro...

Phosphagenics Announces Positive Proof of Concept Results from Studies Utilizing Company's Dermal Drug Delivery Technology

...compounds, such as coenzyme Q10 (CoQ10)and omega-3 fatty acids. About Phosphagenics Limited Phosphagenics is a Melbourne-based, globally drivenbiotechnology company focused on the discovery of new and costeffective ways to enhance the bioavailability, activity, safety anddelivery of proven pharmaceutical...

Phase IIIb Clinical Data Validate the Overall and Cardiovascular Safety Profile of Cycloset (A Quick Release Formulation of Bromocriptine Mesylate) in Patients with Type 2 Diabetes

...orincreased plasma glucose, triglyceride, and free fatty acid levelsin fasting and postprandial states in insulin resistant subjects.Results of published clinical studies suggest that treatment withCycloset(TM) may improve hyperglycemia, glucose intolerance,hyperlipidemia, or aspects of insulin resistance,...

Elixir Pharmaceuticals Presents Preclinical Data Highlighting Its Ghrelin Antagonist Program at the American Diabetes Association's Annual Meeting

...lood glucose and insulin levels, and reductions in fatty liver.The data were presented in poster sessions on Sunday, June 24th,during the American Diabetes Association's 67th Annual ScientificSessions meeting, being held in Chicago, IL. Elixir is focused onthe development of drugs to treat and prevent meta...

Orchestra Therapeutics Announces New Phase II Clinical Data on NeuroVax Demonstrating Marked Expansion of Regulatory T Cell Populations in Patients With Multiple Sclerosis

...e blood cells,pathogenic T cells, attack myelin, a fatty tissue in the centralnervous system, which surrounds and protects nerve fibers. Thispathologic process creates multiple areas of inflammation thatultimately lead to scarring (sclerosis) and that interfere withnormal transmission of nerve impulses. Th...

Acorda Therapeutics Presents Fampridine-SR Data at ACTRIMS Meeting

...butthe smallest axons have a special covering of a fatty substancecalled myelin that acts as insulation to preserve and speed thesenerve signals, much like the insulating cover of an electrical cordhelps preserve the transmission of electricity. In MS, the myelin becomes damaged and the axon cannoteffecti...

New Study Demonstrates that Lubiprostone May Improve Symptom Relief Rates in Adults with Irritable Bowel Syndrome with Constipation (IBS-C)

...tones, a class of compoundsderived from functional fatty acids that occur naturally in thehuman body. The therapeutic potential of prostones was firstidentified by Dr. Ueno. In January 2006, Sucampo Pharmaceuticalsreceived marketing approval from the FDA for its first product,AMITIZA, for the treatment of ...

Acorda Therapeutics Presents Data from its Phase 3 Study of Fampridine-SR in Multiple Sclerosis at the American Academy of Neurology Meeting

...butthe smallest axons have a special covering of a fatty substancecalled myelin that acts as insulation to preserve and speed thesenerve signals, much like the insulating cover of an electrical cordhelps preserve the transmission of electricity. In MS, the myelin becomes damaged and the axon cannoteffecti...

Rituxan Phase II Data in Patients with Relapsing-Remitting Multiple Sclerosis Presented at the American Academy of Neurology

...ystem is thought to attack the body'sown myelin, a fatty substance that surrounds and protects the nervefibers of the brain, spinal cord and optic nerves. There are fourtypes of MS with a wide variety of symptoms and different coursesof disease progression. RRMS is the most common form of MS,accounting for...

Rituxan Phase II Data in Patients with Relapsing-Remitting Multiple Sclerosis Presented at the American Academy of Neurology

...ystem is thought to attack the body'sown myelin, a fatty substance that surrounds and protects the nervefibers of the brain, spinal cord and optic nerves. There are fourtypes of MS with a wide variety of symptoms and different coursesof disease progression. RRMS is the most common form of MS,accounting for...

First Study To Show Positive Benefit On Atherosclerosis For People With Early Signs Of Diseased Arteries

...Atherosclerosis occurs when there is a build-up of fatty orfibrous deposits, to form areas called plaques, in the artery wall.The build-up of plaques causes the artery to narrow and this canreduce the blood supply to vital organs such as the heart andbrain, resulting in symptoms such as angina or transient...

REACH Registry Demonstrates That Multiple Arterial Disease Locations Sharply Increase the Risk of Major CV Events in Outpatients With Atherothrombosis

...) in the wall of a blood vessel. Plaquesconsist of fatty acids and cholesterol, calcium and othermaterials. The rupture of plaques and the subsequent development of a clotcan cause partial or complete blockage of an artery in variousparts of the body. When a vessel in the heart is partially orcompletely b...

British Journal of Cancer Reports Preclinical Evidence of Positive Effect of Rice Bran on Intestinal Cancer

...do concur with the researchers that the shortchain fatty acids and butyrates formed in the colon from thebreakdown of the rice bran are most likely the mechanism that makesthe addition of stabilized rice bran to our daily diet a promisingtreatment for the prevention of colon cancer," said Adelman. About N...