PROTECT-1 Phase II/III Induction-Stage Results for ChemoCentryx's Traficet-EN(TM) Presented in Oral Session at DDW 2009 Conference
... receptor known as 'CCR9', which is selectively
expressed by inflammatory T cells to migrate to the ... In adults, CCR9 is a highly specific receptor
expressed by T cells that migrate selectively to the ... levels of activity, performance or achievements
expressed or implied by any forward-looking statement. Some ...
Micromet Presents Update on BiTE Antibody Pipeline and Reviews Key AACR Presentations at R&D Day
... is a target antigen that is highly and frequently
expressed on many types of solid tumors. MT110 currently ... historical results or from any future results
expressed or implied by such forward-looking statements. ... to differ materially from any future results
expressed or implied by any forward-looking statements ...
Medarex Announces Preclinical Data from Multiple Research Programs Demonstrating Anti-Tumor Activity in Cancer
... in the CXC chemokine receptor family that is
expressed on a variety of cancers including leukemias, ... a component of the cell plasma membrane, that is
expressed on most small cell lung cancers (SCLC). In in ... Glypican-3 is a protein that has been shown to be
expressed in liver cancer. A panel of fully human ...
Micromet Has Started a New Phase 2 Trial with Adecatumumab in Colorectal Cancer Patients
... EpCAM is a cancer target which is highly
expressed in colorectal cancer, and targeted therapies such ...
Apart from being the most highly and frequently
expressed target antigen on colorectal cancer cells, EpCAM ... been shown to drive tumor growth and to be
expressed on colorectal cancer stem cells (1). The ability ...
Vical Pandemic Influenza Vaccines Achieve T-Cell Responses and Cross-Clade Reactivity in Humans
... for infectious diseases or cancer, in which the
expressed protein is an immunogen; cancer immunotherapeutics, in which the
expressed protein is an immune system stimulant; and cardiovascular therapies, in which the
expressed protein is an angiogenic growth factor. The ...
SARS Vaccine Achieves Neutralizing Responses in First U.S. Human Trial
... for infectious diseases or cancer, in
which the
expressed protein is an immunogen; cancer immunotherapeutics, in
which the
expressed protein is an immune system stimulant; and cardiovascular
therapies, in which the
expressed protein is an angiogenic growth factor. ...
Vical Receives Milestone Payment from Merck & Co., Inc. Triggered by Planned Initiation of Investigational Cancer DNA Vaccine Trial
... for infectious diseases or cancer, in which the
expressed protein is an immunogen; cancer immunotherapeutics, in which the
expressed protein is an immune system stimulant; and cardiovascular therapies, in which the
expressed protein is an angiogenic growth factor. The ...
Vical Completes Enrollment and Reports Positive Interim Data in CMV Vaccine Phase 2 Trial
... for infectious
diseases or cancer, in which the
expressed protein is an immunogen; cancer
immunotherapeutics, in which the
expressed protein is an immune system
stimulant; and cardiovascular therapies, in which the
expressed protein is
an angiogenic growth factor. The ...
U.S. Navy and U.S. Army to Develop Dengue DNA Vaccine Formulated With Vical's Vaxfectin(R) Adjuvant
... for infectious
diseases or cancer, in which the
expressed protein is an immunogen; cancer
immunotherapeutics, in which the
expressed protein is an immune system
stimulant; and cardiovascular therapies, in which the
expressed protein is
an angiogenic growth factor. The ...
Vical Expands Applications of Vaxfectin(R) Adjuvant for Infectious Disease and Cancer Vaccines; 80% to 100% of High-Dose Responders in H5N1 Clinical Trials Still Responding at 6 Months
... for infectious
diseases or cancer, in which the
expressed protein is an immunogen; cancer
immunotherapeutics, in which the
expressed protein is an immune system
stimulant; and cardiovascular therapies, in which the
expressed protein is
an angiogenic growth factor. The ...
Karolinska Institutet to Test Vical's Vaxfectin(R) Adjuvant With Preventive Vaccine against HIV Under Sponsorship of Swedish Institute for Infectious Disease Control
... for infectious
diseases or cancer, in which the
expressed protein is an immunogen; cancer
immunotherapeutics, in which the
expressed protein is an immune system
stimulant; and cardiovascular therapies, in which the
expressed protein is
an angiogenic growth factor. The ...
Karolinska Institute to Test Vical's Vaxfectin(R) Adjuvant with Preventive Vaccine against HIV Under Sponsorship of Swedish Institute for Infectious Disease Control
... for infectious
diseases or cancer, in which the
expressed protein is an immunogen; cancer
immunotherapeutics, in which the
expressed protein is an immune system
stimulant; and cardiovascular therapies, in which the
expressed protein is
an angiogenic growth factor. The ...
Vical Announces Breakthrough for Pandemic Influenza DNA Vaccines With Preliminary Human Data
... for infectious
diseases or cancer, in which the
expressed protein is an immunogen; cancer
immunotherapeutics, in which the
expressed protein is an immune system
stimulant; and cardiovascular therapies, in which the
expressed protein is
an angiogenic growth factor. The ...
Medarex Highlights Strength in Antibody Development and Underlying Pipeline Strategy at R&D Day Event in New York City
... that targets CD30, a member of
the TNF family
expressed on CD30-positive lymphomas, including ... that selectively binds to CD19, a molecule
expressed on a broad
range of B-cell malignancies. MDX-1342 ... program.
-- MDX-1203 targets the CD70 molecule
expressed on multiple cancers and
is expected to be the ...
Vical Advances RapidResponse(TM) DNA Vaccine Platform Under $6 Million Grant from NIH
... for infectious
diseases or cancer, in which the
expressed protein is an immunogen; cancer
immunotherapeutics, in which the
expressed protein is an immune system
stimulant; and cardiovascular therapies, in which the
expressed protein is
an angiogenic growth factor. The ...
Patient's Own Infection-Fighting T Cells Put Late-Stage Melanoma Into Long-Term Remission - Without Chemotherapy or Radiation
... specific type of immune
system whose tumor cells
expressed a specific antigen. More studies are
needed to ... to 75 percent
of the patient's tumor cells
expressed the NY-ESO-1 antigen, the entire
tumor regressed ... immune response was broadened to other antigens
expressed by the
tumor cells. Follow-up tests showed T cell ...
Vical Receives $6.3 Million Payment for Continued Funding of Allovectin-7(R) Phase 3 Trial
... for infectious
diseases or cancer, in which the
expressed protein is an immunogen; cancer
immunotherapeutics, in which the
expressed protein is an immune system
stimulant; and cardiovascular therapies, in which the
expressed protein is
an angiogenic growth factor. The ...
Promise of Vical's CMV Vaccine Noted by Independent Experts
... for infectious
diseases or cancer, in which the
expressed protein is an immunogen; cancer
immunotherapeutics, in which the
expressed protein is an immune system
stimulant; and cardiovascular therapies, in which the
expressed protein is
an angiogenic growth factor. The ...
New England Journal of Medicine Publishes Results From a RELISTOR Phase 3 Clinical Study
... actual results to differ
materially from those
expressed or implied by such statements. In
particular, ... actual results to differ materially from
those
expressed or implied by forward-looking statements include, ... time means that actual
events are bearing out as
expressed or implied in such forward-looking
statements.
...
Wyeth and Progenics Announce Preliminary Clinical Trial Results for RELISTOR Oral and Intravenous Formulations
... actual results to differ
materially from those
expressed or implied by such statements. In
particular, ... actual results to differ materially from
those
expressed or implied by forward-looking statements include, ... time means that actual events are
bearing out as
expressed or implied in such forward-looking statements.
...
Micromet Enrolls First Patient in a Phase 1 Clinical Trial with MT110, the First BiTE Antibody for Treatment of Solid Tumors
... molecule (EpCAM or CD326),
which is highly
expressed on colon, lung, breast, prostate, ... historical results or from any future results
expressed or
implied by such forward-looking statements. ... to differ materially from any future results
expressed or implied
by any forward-looking statements ...
Vical Promotes Melanoma Awareness Month With Allovectin-7(R) Video Report
... DNA immunotherapeutics for
cancer, in which the
expressed protein is an immune system stimulant; DNA
vaccines for infectious diseases, in which the
expressed protein is an
immunogen; and cardiovascular therapies, in which the
expressed protein is
an angiogenic growth factor. The ...
Micromet Presents Safety and Efficacy Data from Primate Studies With Two New BiTE Antibodies Developed for Treatment of Leukaemia and Melanoma
... on normal cells, but is
exposed and highly
expressed on melanoma cells. Consistent with ... historical results or from any future results
expressed or
implied by such forward-looking statements. ... to differ materially from any future results
expressed or implied
by any forward-looking statements ...
Vical Receives NIH Grant for an Immunotherapeutic Herpes DNA Vaccine; Herpes Experts at University of Washington and University of Texas to Conduct Preclinical Development
... for infectious
diseases or cancer, in which the
expressed protein is an immunogen; cancer
immunotherapeutics, in which the
expressed protein is an immune system
stimulant; and cardiovascular therapies, in which the
expressed protein is
an angiogenic growth factor. The ...
Vical Receives Payment from AnGes MG for Allovectin-7(R) Phase 3 Pivotal Trial
... for infectious
diseases or cancer, in which the
expressed protein is an immunogen; cancer
immunotherapeutics, in which the
expressed protein is an immune system
stimulant; and cardiovascular therapies, in which the
expressed protein is
an angiogenic growth factor. The ...
Interim Safety Data Favorable for Vical's Phase 2 Trial of DNA Vaccine Against CMV
... for infectious
diseases or cancer, in which the
expressed protein is an immunogen; cancer
immunotherapeutics, in which the
expressed protein is an immune system
stimulant; and cardiovascular therapies, in which the
expressed protein is
an angiogenic growth factor. The ...
Vical Demonstrates Dose-sparing of Protein-based H5N1 Influenza Vaccine With Vaxfectin(TM) Adjuvant
... for infectious
diseases or cancer, in which the
expressed protein is an immunogen; cancer
immunotherapeutics, in which the
expressed protein is an immune system
stimulant; and cardiovascular therapies, in which the
expressed protein is
an angiogenic growth factor. The ...
Vical Licensee Sanofi-aventis Initiates Phase 3 Trial to Reduce Amputations
... for infectious
diseases or cancer, in which the
expressed protein is an immunogen; cancer
immunotherapeutics, in which the
expressed protein is an immune system
stimulant; and cardiovascular therapies, in which the
expressed protein is
an angiogenic growth factor. The ...
Vical Begins Phase 1 Trial of DNA Vaccine Against H5N1 Pandemic Influenza
... for infectious
diseases or cancer, in which the
expressed protein is an immunogen; cancer
immunotherapeutics, in which the
expressed protein is an immune system
stimulant; and cardiovascular therapies, in which the
expressed protein is
an angiogenic growth factor. The ...
Multiple NIH Phase 2 HIV Vaccine Trials Using Vical's Technology Produce Encouraging Results
... for infectious
diseases or cancer, in which the
expressed protein is an immunogen; cancer
immunotherapeutics, in which the
expressed protein is an immune system
stimulant; and cardiovascular therapies, in which the
expressed protein is
an angiogenic growth factor. The ...
Vical Reports Second Quarter 2007 Financial Results, Allowance of Pandemic Influenza IND and Other Advances in Product Development Programs
... for infectious
diseases or cancer, in which the
expressed protein is an immunogen; cancer
immunotherapeutics, in which the
expressed protein is an immune system
stimulant; and cardiovascular therapies, in which the
expressed protein is
an angiogenic growth factor. The ...
Wyeth Reports Publication of Phase 3 Data for Bazedoxifene/Conjugated Estrogens, an Investigational Compound Being Studied for the Treatment of Menopausal Symptoms
... that could cause actual results to differ materially from those
expressed or implied by such statements. In particular, clinical trial data are ... medical and scientific experts and others may differ from ours or those
expressed in the referenced publication. The Phase 3 clinical trial data presented ...
Idenix Pharmaceuticals Successfully Completes Proof-of-Concept Study of IDX184 for the Treatment of Hepatitis C Virus (HCV)
... in hepatitis C, or any potential pipeline candidates, including any
expressed or implied statements regarding the efficacy and safety of IDX184, the ... materially different from any future results, performance or achievements
expressed or implied by such statements. There can be no guarantees that the company ...
MADIT-CRT Trial Meets Primary Endpoint
... actual results could vary materially from the expectations and projections
expressed or implied by our forward-looking statements. These factors, in some ... results to differ materially from those contemplated by the statements
expressed in this press release. As a result, readers are cautioned not to place ...
Micromet's Blinatumomab Achieves Primary Endpoint in Phase 2 Study with Acute Lymphoblastic Leukemia Patients
... be materially different from historical results or from any future results
expressed or implied by such forward-looking statements. These forward-looking ... that may cause actual results to differ materially from any future results
expressed or implied by any forward-looking statements include the risk that product ...
Micromet Presents Update on Blinatumomab's Response Rate and Duration in a Phase 1 Study in Non-Hodgkin's Lymphoma Patients
... be materially different from historical results or from any future results
expressed or implied by such forward-looking statements. These forward-looking ... that may cause actual results to differ materially from any future results
expressed or implied by any forward-looking statements include the risk that product ...
Scientists at The Karmanos Cancer Institute in Detroit Identify Potential New Target for Breast Cancer Therapy
... negative human breast carcinomas and discovered that the protein EZH-2 was
expressed in 74 percent of those cases. Hormone receptor negative breast carcinoma ... of the protein was present. We were surprised that 74 percent of tumors
expressed that EZH-2 protein."
Sixty-one samples that researchers used were ...
FDA Advisory Panel Makes Favorable Recommendation for GlaxoSmithKline and Genmab's ARZERRA(TM) (ofatumumab)
... The CD20 molecule is a key target in CLL therapy because it is highly
expressed in most B-cell malignancies.
Ofatumumab is being developed under a ... performance may differ materially from any future results or performance
expressed or implied by such statements. The important factors that could cause our ...
New Preliminary Data from Two Studies Show Clinical Activity of Neratinib in Combination with Trastuzumab and in Combination with Paclitaxel in Advanced HER-2 Positive Breast Cancer
... that could cause actual results to differ materially from those
expressed or implied by such statements. In particular, clinical trial data are ... that could cause actual results to differ materially from those
expressed or implied by forward-looking statements include, among others, risks ...
Scientific Data Relating to Cinryze(TM) Presented at 6th Annual C1 Inhibitor Deficiency Workshop
... infusion. Our actual results could differ materially from those results
expressed in, or implied by, these forward-looking statements. The development and ... could cause future results to differ materially from the expectations
expressed in this press release. The forward-looking statements contained in this ...