Exacerbate in Medical Technology

Prospective Clinical Advantages of Trabecular Metal(TM) Technology Highlighted in Comparative Study

... term success of the primary surgery and may increase the difficulty and expense of revision reconstruction. Acetabular stress-shielding can also exacerbate patients' osteolytic response to bearing surface particles, potentially further reducing the bony support for the implant. The authors of the study ...

Durezol(TM) in the Treatment of Uveitis and Ganciclovir in the Treatment of Herpetic Keratitis: Studies of Treatments for Leading Causes of Blindness to Be Presented

... infections of the eye or ocular structures. Prolonged use of corticosteroids may increase the hazard of secondary ocular bacterial infections, exacerbate the severity of ocular viral infections, and increase the development of fungal infections of the cornea. It is important to monitor intraocular ...

Sirion Therapeutics Announces Positive Pivotal Uveitis Data for Durezol(TM)

... infections of the eye or ocular structures. Prolonged use of corticosteroids may increase the hazard of secondary ocular bacterial infections, exacerbate the severity of ocular viral infections, and increase the development of fungal infections of the cornea. It is important to monitor intraocular ...

Video: Sirion Therapeutics Launches Durezol for Postoperative Ocular Inflammation and Pain

... or mycobacterial infections of the eye or ocular structures. Prolonged use of corticosteroids may increase the hazard of secondary ocular infections, exacerbate the severity of ocular viral infections, and increase the development of fungal infections of the cornea. It is important to monitor intraocular ...

Radius Selects First Preclinical Candidate From SARM Discovery Program for the Treatment of Muscle Loss and Other Musculoskeletal Conditions

... of 65 suffer from sarcopenia, and there are currently no FDA-approved treatment options available. This deterioration of skeletal strength can also exacerbate other age-related conditions such as osteoarthritis and osteoporosis. Additional chronic diseases that involve loss of muscle strength with a ...

Reduced Lung Capacity Accelerates With Diabetes

... function could add to diabetic morbidity and mortality, and raised concerns about the potential use of inhaled insulin, since it may "trigger or exacerbate pulmonary dysfunction." Recently, makers of inhaled insulin have pulled their products from the market because of poor sales or halted product ...

Recent Studies Suggest Popular 'Diet Pill' Relacore Reduces Acne Breakouts

... News Today, "Acne significantly affects physical and psychosocial well-being, so it is important to understand the interplay between the factors that exacerbate acne. Our study suggests a significant association between stress and severity of acne." This research also confirmed the results of a landmark ...

New England Journal of Medicine Study Shows ERBITUX(R) Improves Survival in Advanced Colorectal Cancer

... half, the event continued beyond 28 days. Monitor patients receiving ERBITUX for dermatologic toxicities and infectious sequelae. Sun exposure may exacerbate these effects In women of childbearing potential, appropriate contraceptive measures must be used during treatment with ERBITUX and for 6 months ...

Despite Serious Health Risks, One in Three Adults with Heart Disease Does Not Believe They Need a Flu Shot This Year

... The flu can worsen underlying medical conditions such as heart disease, as well as lead to co-infections with other viruses and bacteria. The flu can exacerbate heart disease conditions and can lead to conditions like viral or bacterial pneumonia that cause complications of heart disease. Recent studies have ...

Survival Data in FDA Approval for ERBITUX(R) (Cetuximab) Supports use as a Single Agent in Patients with Advanced Colorectal Cancer

... half, the event continued beyond 28 days. Monitor patients receiving ERBITUX for dermatologic toxicities and infectious sequelae. Sun exposure may exacerbate these effects In women of childbearing potential, appropriate contraceptive measures must be used during treatment with ERBITUX and for 6 months ...

Survival Data Available from Erbitux Study in First-Line Treatment of Advanced Head and Neck Cancer

... dermatologic toxicities, complications including S. aureus sepsis and abscesses requiring incision and drainage were reported. Sun exposure may exacerbate these effects. A related nail disorder, occurring in 12% (0.4% Grade 3) of patients, was characterized as a paronychial inflammation. The safety of ...

Survival Data Available From Erbitux Study in First-Line Treatment of Advanced Head and Neck Cancer

... dermatologic toxicities, complications including S. aureus sepsis and abscesses requiring incision and drainage were reported. Sun exposure may exacerbate these effects. A related nail disorder, occurring in 12% (0.4% Grade 3) of patients, was characterized as a paronychial inflammation. The safety of ...

Data Available from Erbitux Phase III Study in First-Line Treatment of Advanced Pancreatic Cancer

... dermatologic toxicities, complications including S. aureus sepsis and abscesses requiring incision and drainage were reported. Sun exposure may exacerbate these effects. A related nail disorder, occurring in 12% (0.4% Grade 3) of patients, was characterized as a paronychial inflammation. The safety of ...

Schering-Plough Addresses Major Milestones and Challenges in Treatment of Patients With Chronic Hepatitis C

... all cases these disorders resolve after stopping PEGINTRON therapy. Ribavirin causes hemolytic anemia. Anemia associated with REBETOL therapy may exacerbate cardiac disease that has led to fatal and nonfatal myocardial infarctions. Patients with a history of significant or unstable cardiac disease should ...

Randomized Phase III Trial Showed Erbitux Significantly Improved Secondary Endpoints of Progression-Free Survival and Disease Control in Metastatic Colorectal Cancer Patients

... dermatologic toxicities, complications including S. aureus sepsis and abscesses requiring incision and drainage were reported. Sun exposure may exacerbate these effects. A related nail disorder, occurring in 12% (0.4% Grade 3) of patients, was characterized as a paronychial inflammation. The safety of ...

Insmed Releases Positive Results from Iplex Phase II HIV-Associated Adipose Redistribution Syndrome Clinical Study

... ability to improve glucose homeostasis. Competitor products such as TH9507 and growth hormone reportedly either do not alter glucose homeostasis or exacerbate it, respectively. When considering that up to 40% of this population has impaired glucose homeostasis, then this property of IPLEX becomes even ...

Schering-Plough Announces Hepatitis C Data Presentations at Digestive Disease Week (DDW) 2007 Annual Meeting

... all cases these disorders resolve after stopping PEGINTRON therapy. Ribavirin causes hemolytic anemia. Anemia associated with REBETOL therapy may exacerbate cardiac disease that has led to fatal and nonfatal myocardial infarctions. Patients with a history of significant or unstable cardiac disease should ...

MedImmune Highlights Advances in Inflammatory Disease Pipeline With Series of Data Presentations

... poster session titled, "Inflammation and Host Defense," on Sunday, May 20 at 8:15 a.m.) -- "Proinflammatory Effects of Type 1 Interferon exacerbate Primary RSV Disease in Susceptible NAB Mice" (Publication Page A210, Poster Board #C56, presented in a poster session titled, ...

Extensive Clinical Data on Erbitux Presented at the 2007 ASCO Annual Meeting

... dermatologic toxicities, complications including S. aureus sepsis and abscesses requiring incision and drainage were reported. Sun exposure may exacerbate these effects. A related nail disorder, occurring in 12% (0.4% Grade 3) of patients, was characterized as a paronychial inflammation. The safety of ...

Faust Pharmaceuticals' Phase IIa Results for Parkinson's Disease Presented at International Congress of Parkinson's Disease and Movement Disorders

... duration of the anti-Parkinsonian action of L-dopa. "Unlike other drugs on the market that increase the duration of L-dopa action, FP0011 did not exacerbate the problem of dyskinesia," said Dr. Brotchie. "If these effects were seen in patients, then over the course of a day such an action ...

Cytos Biotechnology Reports Results from Phase IIa Study with CYT003-QbG10 in Patients Suffering from Atopic Dermatitis

... in the skin that causes chronic inflammation and renders the skin dry, itchy and scaly. Irritants (e.g. wool, soap), allergens and emotional stress exacerbate disease symptoms and further trigger the overactive immune system. There is no cure available. Current medications such as immunomodulators, ...

Data Available From Erbitux Phase III Study in First-Line Treatment of Advanced Lung Cancer

... dermatologic toxicities, complications including S. aureus sepsis and abscesses requiring incision and drainage were reported. Sun exposure may exacerbate these effects. A related nail disorder, occurring in 12% (0.4% Grade 3) of patients, was characterized as a paronychial inflammation. The safety of ...