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Esophageal in Medical Technology

Paclitaxel Poliglumex (OPAXIO(TM)) Added to Cisplatin and Radiation Produces 45% Pathologic Complete Remissions in Patients With Esophageal Cancer

... with potentially resectable, locally-advanced esophageal cancer. Although the addition of chemotherapy to radiation is beneficial, the cure rate for esophageal cancer is low. Standard neoadjuvant treatment for esophageal cancer uses a regimen of cisplatin, and ...

Study in the New England Journal of Medicine Shows Non-Surgical Treatment for Pre-Cancerous Condition of Esophagus is Effective and Reduces Risk for Cancer Development

... progression to more severe forms of dysplasia and esophageal cancer. This and data from other recent trials ... reflux disease (GERD), the normal esophageal lining is replaced with abnormal cells (Barrett's ... the presence of early Barrett's, dysplasia, and esophageal cancer. Comparison of the biopsy results at one ...

Torax Medical Launches Pivotal Clinical Study of New Acid Reflux Treatment

... therapy. GERD is caused by a defective lower esophageal sphincter, a ring-like muscular valve that ... numerous complications including ulcerations and esophageal cancer. The incidence of esophageal cancer is rising at a faster rate than any other ...

Early Esophageal Cancer and Pre-Cancer Eliminated With Non-Surgical Treatment Combination

... which report a 100% eradication rate for early esophageal cancer and pre-cancerous dysplasia ... (GERD) and is a known risk factor for esophageal cancer, the fastest growing cancer in the Western ... in each trial, all patients were cured of their esophageal disease. "This data confirms that early cancer ...

Definitive Outcomes of Radiofrequency Ablation for Barrett's Esophagus Using the HALO Ablation System Reported at the Digestive Disease Week Meeting for Gastroenterologists and Esophageal Surgeons

... ablation using the HALO ablation system for eradicating a pre-cancerous esophageal condition known as Barrett's esophagus. Among them, reports included ... esophagus places a patient at a significantly higher risk for developing esophageal adenocarcinoma," commented David S. Utley, M.D., chief medical officer for ...

Schering-Plough Highlights Hepatitis C Clinical Data Presentations at the European Association for the Study of the Liver (EASL) Annual Meeting

... of varices (43 control vs. 16 treatment). In patients with pre-existing esophageal varices (n=82) there were significantly more events (n=14) in the ... secondary analysis as well as in subjects with pre-existing esophageal varices. Extended Treatment Duration in Chronic Hepatitis C ...

It's Only Heartburn...or is it? Chronic Heartburn a Risk Factor for Precursor to Esophageal Cancer

... These abnormal cellular changes can lead to a type of cancer called esophageal adenocarcinoma, the fastest rising malignancy in the United States, ... must be removed. Dr. Korst specializes in the treatment and research of esophageal cancer and is highly experienced in using both laparoscopic and ...

Researchers Present Safety and Efficacy Results of 429 Patients Treated With Radiofrequency Ablation for Pre-Cancerous Barrett's Esophagus

... today reveal that endoscopic radiofrequency ablation performed in a community practice setting is safe and effective for eradicating a pre-cancerous esophageal condition known as Barrett's esophagus. The study is entitled, "Radiofrequency Ablation of Barrett Esophagus: Outcomes of 429 Patients from a ...

TNFerade(TM) Phase III Data Presented at ASCO

... pancreatic cancer. TNFerade has also been and is currently being evaluated for its potential use in the treatment of several other cancers, including esophageal cancer, rectal cancer, and head and neck cancer. GenVec also uses its proprietary adenovector technology to develop vaccines for infectious diseases ...

New Preliminary Data from Two Studies Show Clinical Activity of Neratinib in Combination with Trastuzumab and in Combination with Paclitaxel in Advanced HER-2 Positive Breast Cancer

... with IV paclitaxel 80 mg/m2, if tolerable, or 70 mg/m2 on days 1, 8 and 15. Patients with solid tumors (endometrial, cervical, colorectal and esophageal cancers) were entered in the phase 1 portion (part 1), and only patients with metastatic ErbB-2 positive breast cancer were enrolled in part 2. ...

Ascenta Therapeutics Announces Multiple Presentations on AT-101 at 2009 ASCO Annual Meeting

... B-cell malignancies (with Rituxan(R)), small cell lung cancer (with Hycamtin(R)), glioma (with Temodar(R), +/- chemoradiotherapy [XRT]) and esophageal cancer (with docetaxel, 5-fluorouracil and XRT). About Ascenta Therapeutics Ascenta Therapeutics, Inc. is a privately-held, clinical-stage ...

RISPERDAL(R) CONSTA(R) (Risperidone) Long-Acting Treatment Delayed the Time to Relapse in Patients with Bipolar I Disorder

... should be used cautiously in patients with a history of seizures or with conditions that potentially lower seizure threshold. Dysphagia: esophageal dysmotility and aspiration can occur. Use cautiously in patients at risk for aspiration pneumonia. Priapism has been reported. Severe priapism ...

CyberKnife Radiosurgery for Lung Cancer Sees Increased Interest and Continued Rapid Growth

... amongst this group of physicians. Discussions by leading thoracic surgeons, such as James Luketich, M.D., Chief of The Heart, Lung and esophageal Surgery Institute at the University of Pittsburgh Medical Center highlighted the efficacy and resulting increased demand for CyberKnife treatments ...

Ascenta Therapeutics Announces Positive Preliminary Results with AT-101 in Docetaxel Refractory Prostate Cancer

... [rituximab]), small cell lung cancer (with Hycamtin(R) [topotecan]), glioma (with Temodar(R) [temozolomide], +/- chemoradiotherapy [XRT]) and in esophageal cancer (with docetaxel, 5-fluorouracil and XRT). Recently, two double-blinded, randomized, controlled trials of the docetaxel + AT-101 combination ...

Sanvar(R) (Debio 8609) for Esophageal Variceal Bleeding

... or Debio 8609 (vapreotide acetate). The immediate release formulation of Sanvar(R), a somatostatin analogue, is used in the treatment of acute esophageal variceal bleeding (EVB). "This is an important step towards completing the U.S. registration of our drug. Sanvar(R) has demonstrated therapeutic ...

Multi-Centre European Clinical Trial Shows Advanced Dysplasia and Early Cancer of Esophagus Cured With Combined Endoscopic Resection and Radiofrequency Ablation With HALO Ablation System

... as in this study. Once dysplasia or cancer occurs, an esophagectomy (surgical removal of the entire esophagus) has been the first-line therapy. esophageal cancer of this type is the fastest growing cancer in industrialized countries. Jacques Bergman, M.D., Associate Professor, Department ...

Takeda's Investigational PPI TAK-390MR Demonstrated Higher Healing Rates Compared to Lansoprazole as the Severity of Erosive Esophagitis Grade Increased, a New Integrated Analysis Showed

... GERD is a chronic condition commonly known as acid reflux disease. GERD can occur when the valve at the lower end of the esophagus, called the lower esophageal sphincter (LES), does not close properly. This valve opens to allow food and liquids to enter the stomach and closes to keep acid and food in the ...

CryoCath Arctic Front(R) Results Published in JACC

... safety data reported in the article confirms the strong safety profile Arctic Front has demonstrated to date. There were no observed reports of atrio esophageal fistula, stroke, death or peri-interventional complications. Phrenic nerve palsies were reported in 7.5 percent of patients treated; in some ...

Ception Therapeutics Initiates Phase II/III Clinical Trial for Its Lead Product Reslizumab in Eosinophilic Esophagitis (EE) in Children

... dose groups or placebo, administered at monthly intervals for four months. The co-primary endpoints of the study are changes in clinical symptoms and esophageal eosinophil levels at the end of therapy. The clinical study is being conducted at multiple centers and will enroll approximately 172 patients. For ...

U.S. Food and Drug Administration Approves ABILIFY(R) (aripiprazole) for the Acute Treatment of Manic and Mixed Episodes Associated With Bipolar I Disorder in Pediatric Patients (10 to 17 Years of Age)

... may exercise strenuously, be exposed to extreme heat, receive concomitant medication with anticholinergic activity, or be subject to dehydration. esophageal dysmotility and aspiration have been associated with antipsychotic drug use, including ABILIFY; use caution in patients at risk for aspiration ...

Potential Breakthrough Cancer Treatment Emerges from MIPS-Funded Clinical Trial Teaming CSA Medical Inc. and University of Maryland Researchers

... reduce and often eliminate pre-cancerous and cancerous lesions in patients, including those with Barrett's esophagus, a precursor to cancer involving esophageal lesions created by chronic acid reflux. Trial results will be presented today at the American College of Gastroenterology's Annual Scientific ...

New Study Shows Once-Monthly Boniva(R) is as Clinically Effective as Once-Weekly Fosamax(R) at Increasing Bone Mineral Density in Postmenopausal Women With Osteoporosis

... of Boniva. Boniva, like other bisphosphonates administered orally, may cause upper gastrointestinal disorders such as dysphagia, esophagitis, and esophageal or gastric ulcer. Boniva is not recommended in patients with severe renal impairment. Adequate intake of calcium and Vitamin D is important in all ...

New Phase III Data Presented for Once Monthly Dosing Regimen of Risedronate to Treat Postmenopausal Osteoporosis

... with severe renal impairment (creatinine clearance Bisphosphonates may cause upper gastrointestinal disorders such as dysphagia, esophagitis and esophageal or gastric ulcer. Patients should pay particular attention to the dosing instructions, as failure to take the drug according to instructions may ...

Cell Therapeutics, Inc. (CTI) Supports Panel Discussion on Women and Lung Cancer on Capitol Hill

... Jill M. Siegfried, Ph.D., Professor and Vice Chair of Pharmacology at the University of Pittsburgh School of Medicine and co-Director of the Lung and esophageal Cancer Program at the University of Pittsburgh Cancer Institute (UPCI). Women and Lung Cancer Lung cancer is the number one cancer killer of women ...

Cell Therapeutics, Inc. (CTI) Sponsors Panel Discussion on Women and Lung Cancer on Capitol Hill

... Jill M. Siegfried, Ph.D., Professor and Vice Chair of Pharmacology at the University of Pittsburgh School of Medicine and co-Director of the Lung and esophageal Cancer Program at the University of Pittsburgh Cancer Institute (UPCI). Women and Lung Cancer Lung cancer is the number one cancer killer of women ...

Kosan's Motilin Receptor Agonist, Licensed to Pfizer, Enters Phase 1 Clinical Trial in Gastroesophageal Reflux Disease

... of disordered upper GI tract motility, resulting in increased ingress of gastric contents into the lower esophagus, together with impairments in esophageal clearance and protection mechanisms. Increased exposure to gastric contents, coupled with reduced ability to clear the bolus, appears to precipitate ...

Addex Achieves Statistically Significant Outcome in Phase IIa Clinical Trial With ADX10059 in Gastro-Esophageal Reflux Disease

... primary objective, the control of 24-hour esophageal pH, with statistical significance, and also ... duration of acid reflux episodes, determined by esophageal pH measurement, was significantly ... in sleep disturbance and increased risk of esophageal damage, was also significantly reduced by ...

DUSA Pharmaceuticals Receives Orphan Drug Desi gnation for Levulan PDT to Treat Esophage al Dysplasia

... Barrett's Esophagus, a Leading Cause of esophageal Cancer WILMINGTON, MASSACHUSETTS--(CCNMatthews - ... Photodynamic Therapy (PDT) for the treatment of esophageal dysplasia. This disease occurs in some patients ... cause of esophageal cancer. The incidence of esophageal cancer is one of the most rapidly growing in the ...

NCCN Updates Esophageal and Gastric Cancer Guidelines

... Practice Guidelines in Oncology(TM) -- esophageal Cancer and Gastric Cancer. The NCCN Guidelines ... (Xeloda(R), Roche) as an option for treatment of esophageal and gastric cancer. The REAL 2 study, the largest ... regimens used for the treatment of advanced esophageal and gastric cancer. A new page entitled ...

Dynogen's DDP733 Reduces Reflux in Phase 1b GERD Study

... - DDP733 reduces esophageal reflux - Waltham, Mass., June 7, 2007 – ... left untreated, complications of GERD can include esophageal erosions or ulcers and abnormal narrowing of the ... of chronic heartburn, left untreated, can lead to esophageal cancer, currently the fastest growing cancer in ...

Dynogen Reports Positive Results in Phase 1B GERD Study

... after the age of 40. If left untreated, complications of GERD can include esophageal erosions or ulcers and abnormal narrowing of the esophagus. Years of chronic heartburn, left untreated, can lead to esophageal cancer, currently the fastest growing cancer in the United States. NGERD ...

New Advances in Gastric Diagnostics: Smaller is Better

... containing a pH receiver and a small radio transmitter, is attached to the esophageal wall at 5 cm above the lower esophageal sphincter, using a proprietary endoscopic delivery system. Normally ...

FDA MedWatch: Avastin (bevacizumab) and Formation of Tracheoesophageal Fistula in a Recent Clinical Study in Patients with Limited-stage Small Cell Lung Cancer

... phase of the study in the context of persistent esophagitis. Additionally, six other cases of TE fistula have also been reported in other lung and esophageal cancer studies using Avastin and chemotherapy alone or with concurrent radiation treatment. Avastin is not approved for the treatment of SCLC. ...

Palatin Technologies and King Pharmaceuticals Report Data Showing Improvements in Sexual Relationship and Self-Esteem in Patients with Erectile Dysfunction Treated with Bremelanotide

... that was likely related to bremelanotide. There were two Serious Adverse Events in Study 17 that were considered likely related to bremelanotide; an esophageal tear, secondary to emesis, and an incident of prolonged erection. About Bremelanotide Bremelanotide is the first in a new class of drugs ...

NCI Researchers Discover Genes That Are Turned on at High Levels in Tumor-associated Blood Vessels of Mice and Humans

... cells derived from cancer patients. They found that the CD276 protein was overexpressed in tumor-associated blood vessels from colon, lung, breast, esophageal and bladder cancers. In addition, the protein was also found to be frequently overexpressed by the tumor cells themselves, indicating that a ...
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(Date:11/23/2009)...TINew research presents strong evidence that the "... outdoor traffic-related pollution and indoor endo...e or the other exposure alone. , Environmental... (UC) College of Medicine have shown that children...rticles and indoor endotoxin during early life are...
(Date:11/23/2009)...O, November 23, 2009 - The time of day matters to ...new paper produced by a research team led by Profe...orough,s vice-principal for research and colleague... the St. George campus. , Capitalizing on thei... tree, the research team examined how poplar trees...
(Date:11/23/2009)...on, CT Current research suggests that a common or...he related report by Nichols et al, "Unique Lipids...ss of TLR2 Ligands Capable of Enhancing Autoimmuni...erican Journal of Pathology . , Multiple scleros... the brain and spinal cord, affects nearly 1 in 70...
Breaking Biology News(10 mins):Exposure to both traffic, indoor pollutants puts some kids at higher risk for asthma later 2Time of day matters to thirsty trees, U of T researcher discovers 2Factors from common human bacteria may trigger multiple sclerosis 2Cardium Completes Initial Patient Evaluation Period for MATRIX Phase 2b Excellarate Clinical Study 4896 1Cardium Completes Initial Patient Evaluation Period for MATRIX Phase 2b Excellarate Clinical Study 4896 2Cardium Completes Initial Patient Evaluation Period for MATRIX Phase 2b Excellarate Clinical Study 4896 3Cardium Completes Initial Patient Evaluation Period for MATRIX Phase 2b Excellarate Clinical Study 4896 4Cardium Completes Initial Patient Evaluation Period for MATRIX Phase 2b Excellarate Clinical Study 4896 5Cardium Completes Initial Patient Evaluation Period for MATRIX Phase 2b Excellarate Clinical Study 4896 6Cardium Completes Initial Patient Evaluation Period for MATRIX Phase 2b Excellarate Clinical Study 4896 7Cardium Completes Initial Patient Evaluation Period for MATRIX Phase 2b Excellarate Clinical Study 4896 8Tamoxifen May Up Risk of Second More Aggressive Breast Cancer 55316 1Tamoxifen May Up Risk of Second More Aggressive Breast Cancer 55316 2SuperSonic Imagine Receives FDA Approval for Aixplorer Ultrasound System 13688 1SuperSonic Imagine Receives FDA Approval for Aixplorer Ultrasound System 13688 2SuperSonic Imagine Receives FDA Approval for Aixplorer Ultrasound System 13688 3SuperSonic Imagine Receives FDA Approval for Aixplorer Ultrasound System 13688 4
(Date:11/25/2009)...aliforniaMakesLittleProgresstoImproveOverallOutcom...re-USNewswire/-- Today,LungCancerAlliance-Califor...er .The2009ReportCardisanassessmentofprogressbeing....LCA-CAisachapterofLungCancerAlliance(LCA),theonly...upportandadvocacyforpeoplelivingwithoratriskforlun...
(Date:11/25/2009)...ES (Nov. 25, 2009) Melvin R. Kaplan, MD, FACP, a ...research institute that became Los Angeles Biomedi...er (LA BioMed), will be honored by the American Co...he care of patients. , At its April 22, 2010 mee...s will present Dr. Kaplan with the Ralph O. Claypo...
(Date:11/25/2009)...n fruit fly study may lead to new drugs for people... (HealthDay News) -- Sphingadienes, natural lipid ...ent in treatments for colon cancer, California res...inary, but the study authors pointed out that they...ction against colon cancer. , In the study, Dr....
(Date:11/25/2009)... Citing support for recent enforceme...s, the National Association of Chain Drug Stores (...inistration (FDA). The letter expresses the Assoc... both domestic and foreign, that are engaged in a ...ing and dispensing of prescription medications. ,...
(Date:11/25/2009)...HINGTON,Nov.25/PRNewswire-USNewswire/--/EINNews/EI...sssyndication,introducesitsnewesthealth-relatedpub...wsToday( http://h1n1.einnews.com ). ,, H1N1News...micfromgovernments,newsoutletsandresearchcentersth...latestnewsontheglobaloutbreakwithreportsfromeverys...
Breaking Medicine News(10 mins):Health News:Lung Cancer Alliance-California Releases 2nd Annual State-Specific Report Card On Lung Cancer 2Health News:1 of LA BioMed's founders to be honored 2Health News:Natural Soy Component May Help Treat Colon Cancer 2Health News:NACDS Supports FDA Enforcement Against Rogue Internet Pharmacy Websites 2Health News:H1N1 News Today Examines the Swine Flu Virus From a Global Perspective; Read the Latest H1N1 Virus Vaccine & Prevention News From EIN News 2
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