Human Genome Sciences and GlaxoSmithKline Announce Positive Phase 3 Study Results for BENLYSTA(TM) in Systemic Lupus Erythematosus
... patients with serologically active systemic lupus
erythematosus (SLE). In the placebo-controlled BLISS-52 study, ... agreement.
About Systemic Lupus
erythematosus
Systemic lupus
erythematosus (SLE) is a chronic, life-threatening autoimmune ...
Study Results Show Epratuzumab Provided Clinically Meaningful Reduced Disease Activity in Patients With Lupus
... with active
moderate and severe systemic lupus
erythematosus (SLE). These findings were
presented at the ... investigation for
the treatment of systemic lupus
erythematosus (SLE). CD22 is a B-cell
specific surface protein ... Morris Plains,
NJ, USA.
About systemic lupus
erythematosus (SLE)
Systemic ...
Human Genome Sciences Completes Enrollment in Second Phase 3 LymphoStat-B(R) Trial
... in patients with
active systemic lupus
erythematosus (SLE). Belimumab is being developed by
HGS and ... Systemic Lupus Erythematosus
Systemic lupus
erythematosus (SLE) is a chronic, life-threatening
autoimmune ... at http://www.lupus.org or the European Lupus
erythematosus Federation at
http://www.elef.rheumanet.org .
...
Human Genome Sciences Completes Enrollment in First of Two Phase 3 Lymphostat-B(R) Trials
... in patients with active
systemic lupus
erythematosus (SLE). LymphoStat-B is being developed by HGS
and ... Systemic Lupus Erythematosus
Systemic lupus
erythematosus (SLE) is a chronic, life-threatening
autoimmune ... at http://www.lupus.org or the European Lupus
erythematosus Federation at
http://www.elef.rheumanet.org .
...
Human Genome Sciences Reports Positive Data from Long-Term Treatment with LymphoStat-B(R) in Patients with Active Systemic Lupus Erythematosus
... of care in
patients with active systemic lupus
erythematosus (SLE). The results will
be the subject of an oral ... under the
agreement. About Systemic Lupus
erythematosus Systemic lupus
erythematosus (SLE) is a chronic, life-threatening
disease. The ...
Human Genome Sciences Reports Substantial Progress Toward Commercialization and Announces 2009 Goals at JPMorgan Healthcare Conference
... the results of our two Phase 3 trials of LymphoStat-B in systemic lupus
erythematosus (SLE) in July and November, respectively, and expect to file marketing ... trials of LymphoStat-B (belimumab) in patients with active systemic lupus
erythematosus (SLE). The Company expects to report the first Phase 3 data for ...
Human Genome Sciences Reports Positive Long-Term Data for LymphoStat-B in Patients With Active Systemic Lupus Erythematosus
... with standard of care in
patients with serologically active systemic lupus
erythematosus (SLE). The
results are the subject of a number of oral and poster ... Foundation of America at
http://www.lupus.org or the European Lupus
erythematosus Federation at
http://www.elef.rheumanet.org . For more information about ...
Rigel's R788 Slows Progression of Murine Lupus in Preclinical Studies
... Lead drug candidate may help patients with Systemic Lupus
erythematosus (SLE)
SOUTH SAN FRANCISCO, Calif., April ... levels that decreased
following the onset drug treatment.
Systemic Lupus
erythematosus (SLE)
Lupus is an autoimmune disease, which affects nearly 2 ...
Steps Toward Stopping Autoimmune Disease: International Consortium Identifies Genes Linked to Lupus
... genetic study
has identified multiple genes linked to systemic lupus
erythematosus (SLE),
or lupus, a debilitating autoimmune disease that affects an ... Lupus Research (ALR) formed and supported the
International Systemic Lupus
erythematosus Genetics (SLEGEN) Consortium,
charging scientists with searching for ...
Coley Pharmaceutical Group Diversifies Pipeline with First-in-Class TLR Antagonist for the Treatment of Systemic Lupus Erythematosus
... November 10, 2007 from 8:00am to 4:30pm EST. About Systemic Lupus
erythematosus (SLE)(1) SLE is a chronic autoimmune disease that affects nearly ... safety and tolerability of CPG 52364 for the treatment
of Systemic Lupus
erythematosus (SLE); confirmation of TLR7/8/9 as a target
for SLE; ; Coley's ability to ...
Lupus Research Institute Highly Encouraged by Benlysta(TM) Trial Results
... lupus.
To learn more about lupus clinical trials, log on to www.LupusTrials.org .
About Lupus
Systemic lupus
erythematosus (SLE) or lupus, one of the nation's least recognized major diseases, is a chronic and potentially fatal autoimmune disorder that affects more than ...
New Data Shows Blood Pressure Reduction Therapy with BENICAR(R) and BENICAR HCT(R) Effectively Reduces Blood Pressure in Elderly Patients to Target Blood Pressure
... occur in patients with or without a history of allergy or bronchial asthma, but are more likely in patients with such a history.
Systemic Lupus
erythematosus
Thiazide diuretics have been reported to cause exacerbation or activation of systemic lupus erythematosus.
Lithium Interaction
Lithium ...
Following Encouraging Results Anthera to Continue IMPACTS Trial for the Prevention of Acute Chest Syndrome in Patients With Sickle Cell Disease
... of diseases. The company has also acquired exclusive and worldwide rights to a peptide fusion protein, A-623, for the treatment of systemic lupus
erythematosus (SLE) and other autoimmune diseases from Amgen. For more information, please visit http://www.anthera.com .
MEDIA CONTACT:
Anne ...
Medarex Announces Initiation of Phase 2 Clinical Development Program for the Treatment of Lupus
... today that its partner MedImmune, Inc. has
initiated a Phase 2A multi-dose clinical trial of MEDI-545 for the
potential treatment of systemic lupus
erythematosus (SLE or lupus).
MEDI-545 is a fully human antibody generated by Medarex's UltiMAb Human
Antibody Development System(R). Under the terms of the ...
Human Genome Sciences Reports Progress With Late-Stage Products and New Initiatives
... LymphoStat-B(R) (belimumab), a human monoclonal antibody that
neutralizes BLyS(TM) (B-lymphocyte stimulator), for the treatment of
systemic lupus
erythematosus SLE
In November 2007, Phase 2 results were presented at the Annual
Scientific Meeting of the American College of Rheumatology, which
demonstrated ...
DSMB Supports Continuation of Anthera Phase II Impacts Trial for the Prevention of Acute Chest Syndrome in Patients With Sickle Cell Disease
... of diseases. The company has also acquired exclusive and
worldwide rights to a peptide fusion protein, A-623, for the treatment of
systemic lupus
erythematosus (SLE) and other autoimmune diseases from
Amgen. For more information, please visit http://www.anthera.com .
MEDIA CONTACT:
Anne Bowdidge (650) ...
Trubion Initiates Phase 1/2 Study of TRU-016 in CLL, Announces Next-Generation Product Candidate for RA and Provides Product Pipeline Update
... in autoimmune and inflammatory diseases."
TRU-015 and SBI-087 for SLE
Wyeth intends to pursue clinical evaluation of SBI-087 in Systemic
Lupus
erythematosus (SLE) and an investigational new drug filing is
expected by the end of the year. As a result, Wyeth no longer intends to
evaluate TRU-015 in a ...
Anthera Enters Into Manufacturing Agreements for Varespladib in Preparation for Pivotal Phase III Trials
... of diseases. The company has also acquired exclusive and
worldwide rights to a peptide fusion protein, A-623, for the treatment of
systemic lupus
erythematosus (SLE) and other autoimmune diseases from
Amgen. For more information, please visit http://www.anthera.com .
Contact: Anne Bowdidge (650) 218-6900
...
Tolerx Achieves Milestone with Completion of Phase Ib Clinical Study of TRX1 in Cutaneous Lupus Erythematosus
... completion of a Phase Ib clinical study of TRX1, a novel
humanized anti-CD4 monoclonal antibody (MAb), in subjects with refractory
cutaneous lupus
erythematosus (CLE). The Phase Ib study was designed to
assess the safety, tolerability, and pharmacokinetics of TRX1. Tolerx has
received a milestone payment from ...
Trubion Pharmaceuticals Announces Presentation of Positive Data From Phase IIb and Re-treatment Studies With TRU-015 in Patients With Rheumatoid Arthritis
... cells. In addition to the ongoing development of TRU-015 for
RA, investigational new drug applications have been filed for TRU-015 for
systemic lupus
erythematosus and non-Hodgkin's lymphoma. Trubion's SMIP
drug candidates represent a novel class of immunotherapeutics that the
company believes possess enhanced ...
Trubion Announces Preliminary Analysis of Phase IIb Results With TRU-015 in Rheumatoid Arthritis
... cells. In addition to the ongoing development of TRU-015 for
RA, investigational new drug applications have been filed for TRU-015 for
systemic lupus
erythematosus and non-Hodgkin's lymphoma. Trubion's SMIP
drug candidates represent a novel class of immunotherapeutics that the
company believes possess enhanced ...
Human Genome Sciences Reports That a Phase 2 Study of LymphoStat-B
Showed Significant Reductions in Disease Activity in Patients with
Active Systemic Lupus Erythematosus
... of life in
patients with active systemic lupus
erythematosus (SLE). The
52-week and 76-week results of the ... under the agreement.
About Systemic Lupus
erythematosus
Systemic lupus
erythematosus (SLE) is a chronic,
life-threatening disease. The ...
La Jolla Pharmaceutical Announces Positive Interim Antibody Results
From Riquent Lupus Phase 3 Trial
... of Riquent(R) (abetimus sodium), its drug
candidate for systemic lupus
erythematosus ("lupus" or "SLE").
Analyses of interim antibody data indicate that ... known as LJP 394, our drug candidate for the treatment
of systemic lupus
erythematosus ("lupus"), and any other drug
candidate that we may develop, including the ...
Cellerant Therapeutics Reversed Autoimmune Disease in Lupus Mice
with Transplant of Purified Donor Blood Stem Cells
... (blood forming) stem cells (HSC) in a mouse study of
Systemic Lupus
erythematosus (SLE). Subjects that underwent this
procedure exhibited improved overall ... blood disorders and autoimmune disease.
About Lupus
Systemic lupus
erythematosus (SLE), also called lupus, is an
autoimmune disorder characterized by the ...
La Jolla Pharmaceutical Provides Update on Interim Antibody Results
From Riquent Lupus Phase 3 Trial
... similar expression. The analyses of clinical results of Riquent,
previously known as LJP 394, our drug candidate for the treatment
of systemic lupus
erythematosus ("lupus"), and any other drug
candidate that we may develop, including the results of any trials
or models that are ongoing or that we may initiate ...
Study: Identical Doses of BiDil Components Are Not Bioequivalent to
the Fixed Dose Combination-BiDil-Used in A-HeFT
... Levitra((R)), Cialis((R))) could result in
severe hypotension.
Treatment with hydralazine may produce a clinical picture
simulating systemic lupus
erythematosus (SLE) including
glomerulonephritis. If SLE-like symptoms occur, discontinuation of
BiDil should be considered. Residua have been detected many ...
Rituxan Phase II Data in Patients with Relapsing-Remitting Multiple
Sclerosis Presented at the American Academy of Neurology
... been reported
in Rituxan-treated patients including those with hematologic
malignancies or with certain autoimmune diseases such as systemic
lupus
erythematosus (SLE), an indication for which Rituxan has not
been approved.
About Rituxan
Rituxan is a therapeutic antibody being studied in ...
Rituxan Phase II Data in Patients with Relapsing-Remitting Multiple
Sclerosis Presented at the American Academy of Neurology
... been reported
in Rituxan-treated patients including those with hematologic
malignancies or with certain autoimmune diseases such as systemic
lupus
erythematosus (SLE), an indication for which Rituxan has not
been approved.
About Rituxan
Rituxan is a therapeutic antibody being studied in ...
ZymoGenetics Reports Results From Atacicept Phase 1b Clinical Trial
in B-Cell Chronic Lymphocytic Leukemia
... necrosis factor family that promote B-cell survival
and autoantibody production associated with certain autoimmune
diseases such as systemic lupus
erythematosus (SLE). Current data
indicates that levels of BLyS and APRIL are elevated in patients
with rheumatoid arthritis, SLE and B-cell malignancies. ...
Active Biotech presents new pre-clinical data for the 57-57 project
at the 8th World Congress on Inflammation
... of steroid.
Lund, June 18, 2007
Active Biotech AB (Publ)
Sven Andréasson President & CEO
About SLE and 57-57 Systematic Lupus
erythematosus (SLE) is a
disease of the connective tissues that can cause inflammation and
damage to the connective tissue in many different organs. The
disease, ...
Aspreva and Roche Announce Preliminary Results for Phase III Study
Evaluating CellCept in Lupus Nephritis
... will host a
conference call today at 9:30 a.m. ET (6:30 a.m. PT) to discuss
these preliminary results.
About Lupus Nephritis
Systemic lupus
erythematosus (SLE), commonly called lupus, is a
chronic autoimmune disease that causes the body to attack its own
tissues and joints. Lupus nephritis, considered ...
Corgenix Reports New Clinical Data Correlating AtherOx Technology
With Vascular Disease
... complex (anti-AtherOx) with vascular thrombosis
(particularly with arterial thrombosis) in patients with autoimmune
diseases such as systemic lupus
erythematosus (SLE) and
anti-phospholipid syndrome. The study looked at 113 SLE patients
(94 with secondary anti-phospholipid syndrome and 19 without) ...