effector

Opexa Therapeutics Reports Positive Top-line Data in Phase I/II Extension Trial with Tovaxin for Multiple Sclerosis

...ine. The induction ofanti-idiotypic cytotoxic CD8+ effector T-cells and anti-ergotypicCD4+CD25+FoxP3 positive Tregs is believed to provide atherapeutically effective dual mechanism of protection to patientstreated with Tovaxin(TM). The observed regulatory immune responseshave been shown to collectively correl...

Research Indicates Geron's Human Embryonic Stem Cell-Based Therapeutic for Spinal Cord Injury Evades Direct Attack by the Human Immune System

...cells were tested for susceptibility toboth immune effector cells and sera from normal healthyindividuals. GRNOPC1 cells stimulated very low levels of T cellproliferation. Allogenic T cell proliferation is a standard measureof immune recognition of foreign transplanted tissue. Even whenGRNOPC1 cells were expo...

Opexa Presents Tovaxin Research at Federation of Clinical Immunology Societies Annual Meeting

...ine. The induction ofanti-idiotypic cytotoxic CD8+ effector T-cells and anti-ergotypicCD4+CD25+FoxP3 positive Tregs is believed to provide atherapeutically effective dual mechanism of protection to patientstreated with Tovaxin(TM). The observed regulatory immune responseshave been shown to collectively correl...

MedImmune and Micromet Publish Data on Novel Anti-Cancer BiTE Molecule

...uction approached 100percent even at low ratios of effector T cells to target cells. Inanimal models, the BiTE compound redirected unstimulated human Tcells to inhibit outgrowth of transplanted human tumor cells.Time-lapsed videomicroscopy showed that bscEphA2xCD3 triggered Tcells to destruct tumor cells over...

Opexa Therapeutics Reports Positive Top-line Data in Phase I/II Dose Escalation Trial with Tovaxin for Multiple Sclerosis

...ine. The induction ofanti-idiotypic cytotoxic CD8+ effector T-cells and anti-ergotypicCD4+CD25+FoxP3 positive Tregs is believed to provide atherapeutically effective dual mechanism of protection to patientstreated with Tovaxin(TM). The observed regulatory immune responseshave been shown to collectively correl...