Degenerative in Medical Technology

Back to Normal: Surgery Improves Outcomes for Spine Patients

... -- People with the spine disease called degenerative spondylolisthesis * -- who choose surgical ... of surgeries completed each year to address degenerative spine conditions, yet, there has never been a ... spinal stenosis; and spinal stenosis with degenerative spondylolisthesis. To be ...

MitraClip(R) Therapy Data Demonstrate Clinical Benefit in High-Risk Patients With Mitral Regurgitation

... Congestive Heart Failure in both Functional and degenerative MR Patient Populations BARCELONA, Spain, May ... either functional mitral regurgitation (FMR) or degenerative mitral regurgitation (DMR) improves patient ... patients suffering from significant functional or degenerative MR," said Dr. Kar. "Patients otherwise unable to ...

Aching Back? Cholesterol Medication Might Help

... that using statins may be useful in treatment for degenerative disc disease LAS VEGAS, Feb. 22 /PRNewswire-USNewswire/ -- Back pain, a hallmark of degenerative disc disease, sends millions of people to their ... their quest to discover ways to stop or reverse degenerative disc disease, orthopaedic researchers have been ...

Gene Therapy Provides Vision to People who Were Nearly Blind

... blindness in people with a variety of retinal degenerative diseases," says Jean Bennett, M.D., Ph.D., who is ... across the United States are affected by retinal degenerative diseases which include: macular ... source of non-governmental funding for retinal degenerative disease research in the world. The urgent mission ...

First Human Implant of New Archus Orthopedics Facet Replacement System

... company's product line for treating spinal stenosis, a condition in which degenerative changes in the facet joints result in compression of spinal nerves ... implants to treat a variety of spine disorders resulting from degenerative changes in the facet joints. Archus has received venture capital funding ...

MitraClip Device Preliminary Data Suggests Improved Heart Function and Relief from Heart Failure Symptoms in Functional Mitral Regurgitation Patients

... a new, less-invasive method of valve repair for both functional MR and degenerative MR patients." About Mitral Regurgitation MR is the most common type of ... in the study is open to several patient groups: -- Patients with either degenerative or functional MR -- Patients who are good surgical candidates and are ...

The Pittsburgh Life Sciences Greenhouse Relocates Therapeutics Company to Pittsburgh

... cause the cognitive decline associated with Alzheimer's disease and other degenerative diseases of the human brain. The societal costs of neurodegenerative ... cause the cognitive decline associated with Alzheimer's disease and other degenerative diseases of the human brain. Toxic proteins play a crucial role in a large ...

Cognition Therapeutics Closes Series A Financing to Advance Drug Candidates for Alzheimer's Disease

... of small molecule therapeutics targeting the toxic proteins that cause the cognitive decline associated with Alzheimer's disease and other degenerative diseases of the human brain. Toxic proteins play a crucial role in a large class of diseases, and there are currently no therapeutics available to ...

Neuroscience Researcher Has Positive Message for International Alzheimer's Awareness Week, July 6 - 12: 'Even Though World Economy is Declining, Alzheimer's Research is Advancing'

... economic news and rising global tensions, an American neuroscience researcher has a message of hope: The answer for Alzheimer's disease and other degenerative diseases of the brain that cause memory loss may be much closer than we realize. Mark Underwood, president of the Madison, Wisconsin-based ...

Three Surgeons in East Texas Are Successfully Integrating a Novel Stem Cell Procedure for Spine Surgeries

... spinal degeneration will likely continue to increase. The potential of stem cells and regenerative medicine is virtually limitless for treatments of degenerative diseases since adult stem cells have the remarkable potential to differentiate and become new tissues such as bone, tendon, cartilage and heart ...

Fate Therapeutics Announces First Patient Treated in Phase 1b Clinical Trial of FT1050 for Hematopoietic Stem Cell Support

... approach has broad therapeutic potential in areas such as regenerative medicine, hematological diseases, metastatic cancer, traumatic injury and degenerative diseases. In addition, Fate Therapeutics and Stemgent have formed an alliance - Catalyst - a collaborative program to provide its partners with ...

Sirion Therapeutics Announces Clinical Data Presentations at the 2009 Association for Research in Vision and Ophthalmology (ARVO) Annual Meeting

... Number: 4919 Sirion Therapeutics Poster Presentations Featuring Retinal Research Accumulation of Toxic Retinal Fluorophores in Various degenerative Retinal Diseases Session Date/Start Time: Wednesday May 6, 8:30-10:15 am Posterboard Number: A444 - Program Number: 4188 ...

Processed Tomato Products May Protect Against Inflammation, According to a Study Presented at the Experimental Biology Meeting

... cardiovascular disease, cancer, obesity, metabolic syndrome, type 2 diabetes, osteoporosis, periodontal disease, rheumatoid arthritis, neurological degenerative disorders, and inflammatory bowel disorders. There is growing interest in the role that diet may play in reducing inflammation in order to protect ...

Pfizer and Medivation Initiate Phase 3 Trial of Dimebon Added to Donepezil in Patients with Alzheimer's Disease

... CONCERT study, please visit www.concertstudy.com or call 877-888-6386. About Alzheimer's Disease Alzheimer's disease is a progressive degenerative brain disorder that gradually destroys a person's memory and ability to learn, reason, make judgments, communicate and carry out daily activities. ...

First Swiss Patients Treated with the Percutaneous MitraClip(R) System

... available in the European Union which provides a non-surgical mitral valve repair option for patients suffering from the effects of functional and degenerative mitral regurgitation (MR). Mitral regurgitation is the most common type of heart valve insufficiency in Europe and the United States, affecting ...

TissueGene Announces Regulatory Allowance to Initiate Phase IIa Study of TG-C in South Korea for Osteoarthritis of the Knee

... IIa clinical trial is designed as a randomized, multi-center study in order to evaluate the safety and efficacy of TG-C in patients with Grade IV degenerative Joint Disease (DJD) of the knee, who have been unresponsive to existing therapies. The patients will receive an intra-articular injection to the ...

Applying Clinical Findings to the Practice of Medicine

... Underlying Bone and Cartilage Disorders." This research outlines mouse genetics studies on the molecular backgrounds of representative degenerative skeletal disorders, like debilitating conditions such as osteoporosis and osteoarthritis, which are suffered by millions of people. The molecular ...

Merck Serono's Safinamide Significantly Improved Motor Function in Patients With Advanced Parkinson's Disease in a Phase III Pivotal Trial

... and reduction of glutamatergic activity by inhibiting glutamate release. About Parkinson's disease Parkinson's disease is a degenerative disorder of the central nervous system that often impairs the patient's motor skills and speech. Parkinson's disease belongs to a group of conditions ...

ESBATech's Antibody Fragment Enters Phase I/IIa Clinical Development in Osteoarthritis with the Potential for Disease-Modifying Activity

... cartilage degeneration. Blocking TNF alpha offers the opportunity to attack both aspects, managing pain and structure modification. Because of the degenerative nature of OA, every year more than 130,000 knee replacement surgeries are performed in the U.S. alone. Similar numbers are seen in Europe and other ...

AFFiRiS Begins Development of a Parkinson's Vaccine

... of a Parkinson's vaccine. The vaccine, known as PD01, can be used to target a specific protein that is closely associated with the causes of this degenerative neurological disease. Excellent product candidates from discovery studies have prompted the company to file a patent application and proceed ...

Two-Year Follow-Up Data Demonstrates Preservation of Adequate Mitral Valve Area in Patients Treated with the MitraClip(R) System

... devices (31 percent). Patients with functional MR had a slightly smaller mean MVA, both at baseline and at discharge, but did not differ from degenerative MR patients at later follow- up. These hemodynamic results are consistent with reports of surgical edge-to- edge repair which also have shown that ...

Schering-Plough Reports Preladenant Meets Primary Endpoint in Phase II Dose-Finding Trial for Parkinson's Disease

... disorders without some of the complications of standard dopaminergic treatments. Parkinson's disease is an age-related, progressive, degenerative brain disease that currently affects one out of 100 people over the age of 60 (approximately 500,000 people in the U.S. alone). It is believed to be ...

Aiming at Multiple Alzheimer's Proteins May be Key to Success

... Alzheimer's disease, macular degeneration and glaucoma by funding the best research worldwide, and to informing the public about these age-related, degenerative diseases. Available Topic Expert(s): For information on the listed expert(s), click appropriate link. Dr. Donald Weaver ...

Interleukin Genetics to Present Important New Findings at 2008 World Congress on Osteoarthritis

... form of the disease that adds further complications to the patient's daily activities. About Osteoarthritis Osteoarthritis is a debilitating, degenerative joint disease and the leading cause of physical disability in modern societies. According to data on the American College of Rheumatology website, ...

Sangamo BioSciences Initiates Phase 2 Clinical Trial of Treatment for Amyotrophic Lateral Sclerosis (ALS)

... SGMO ) announced today that it has opened a Phase 2 clinical trial (SB-509-801) to evaluate its drug, SB-509, in subjects with ALS, a progressive, degenerative motor-neuron disease for which there are limited treatment options and no cure. Sangamo's drug, SB-509, is an injectable formulation of a ...

The University of Nottingham in the British Midlands Announces Breakthrough in Parkinson's Disease Research

... of brain degeneration, or nerve cell loss, seen in Lewy body disease and Parkinson's disease, which could lead to more targeted drugs to treat the degenerative conditions. The study has been carried out by Professor John Mayer and Dr Lynn Bedford in the University's School of Biomedical Sciences, in ...

First Ever Study on Alzheimer's Disease Treatment in Hispanics Presented at Major Medical Meeting

... There is an established association between the loss of acetylcholine, a brain chemical involved in memory and thinking, and AD. In a progressively degenerative disease such as Alzheimer's, improvement, stabilization or a less-than-expected decline over time is considered a positive response to treatment. ...

New Data Highlight Positive Results of Namenda(R) (memantine HCl) Once-Daily Extended-Release Formulation

... dizziness (4.7% vs 1.5%), diarrhea (5.0% vs 3.9%), and headache (5.6% vs 5.1%). About Alzheimer's Disease Alzheimer's disease is a progressive, degenerative disease of the brain and the most common type of dementia. Dementia is used to describe the progressive loss of cognitive, intellectual, or ...

Impliant Launches Less-Invasive Version of Patented TOPS(TM) Spine System

... device, is designed to stabilize but not fuse the L3-4 or L4-5 vertebral level to alleviate pain stemming from spinal stenosis with or without degenerative facet arthrosis and spondylolisthesis. Following a laminectomy and medial facetectomy, the device is affixed to the spine via four pedicle screws ...

Kiwifruit: Antioxidant Power in Quantity and Quality

... C content of kiwifruit. While one cannot necessarily translate increased antioxidants in the bloodstream into a potential decreased risk of chronic degenerative disease without further long- term clinical studies, kiwifruit appears to be a strong antioxidant performer. Beyond antioxidants, kiwifruit play an ...

Pharmaxis Long-Term Safety Study of Bronchitol Completes

... that of patients without the disorder; and an increased overall cost to the US health system of US$630 million. Bronchiectasis is an incurable, degenerative and chronic lung condition that makes breathing difficult through excessive mucus build up in the lungs. Forward-Looking Statements The ...

Radius Selects First Preclinical Candidate From SARM Discovery Program for the Treatment of Muscle Loss and Other Musculoskeletal Conditions

... other diseases. About Sarcopenia About 17% of men and 24% of women under the age of 70 suffer from age-related muscle wasting, or sarcopenia. The degenerative loss of skeletal muscle mass and strength contributes to frailty, immobility, and the loss of independence in older adults, with prevalence rising to ...

Impliant Restarts Pivotal Clinical Trial for Patented TOPS(TM) Spine System

... device, is designed to stabilize but not fuse the L3-4 or L4-5 vertebral level to alleviate pain stemming from spinal stenosis with or without degenerative facet arthrosis and spondylolisthesis. Following a laminectomy and medial facetectomy, the device is affixed to the spine via four pedicle screws ...

Phreesia Announces Clinical Initiative to Better Manage Symptoms of Parkinson's Disease

... http://www.newscom.com/cgi-bin/prnh/20080220/NYW106LOGO ) Affecting about one million people in the United States, Parkinson's disease is a degenerative disorder that impairs nerve cells causing patients to experience tremors, slowness of movement, muscle rigidity, and difficulty with balance. Drug ...

NPS Reports Successful GATTEX(TM) Extension Study

... PN. Long-term complications of the condition may include an increased risk of systemic infections due to the presence of an intravenous feeding line, degenerative changes in the bones and nerves due to vitamin and mineral deficiencies, and liver failure. Potential benefits derived from reduced dependence on ...

Alseres Pharmaceuticals Concludes Enrollment in the Cethrin(R) Phase I/IIa Clinical Trial in Acute Spinal Cord Injury

... Inc. (Nasdaq: ALSE ) is a biotechnology company engaged in developing breakthrough regenerative therapeutics to treat traumatic injuries and degenerative diseases. The Company maintains a world- class intellectual property position in the field of regenerative therapeutics. The Company's energy and ...

Alseres Pharmaceuticals Initiates the ALTROPANE(R) POET-2 Phase III Clinical Trial Program

... Inc. (Nasdaq: ALSE ) is a biotechnology company engaged in developing breakthrough regenerative therapeutics to treat traumatic injuries and degenerative diseases. The Company maintains a world- class intellectual property position in the field of regenerative therapeutics. The Company's energy and ...

Raydiance Collaborates With Rutgers University and Nation's Largest Tissue Bank to Develop Innovative Tissue Processing Approaches

... be able to disrupt and reinvent dermal tissue processing as we know it. This is great news for burn victims as well as those suffering from cancer, degenerative joint disease, arthritis and other skin trauma." Bruce Stroever, President and CEO of MTF, said "Over 900,000 Americans receive tissue transplants ...

NeoVista, Inc. Presents New Data on Its Novel Wet AMD Therapy at AAO

... data provides important evidence that this novel concomitant treatment approach may provide more sustainable options for those suffering from this degenerative condition," said Dr. Heier. "NeoVista's targeted beta radiation in this study demonstrated its differences from previous attempts by the medical ...

New Data Shows Ongoing Benefits of Percutaneous MitraClip(R) Device for Patients With Mitral Regurgitation

... physicians to refer such patients to EVEREST investigators." Enrollment in the study is open to a range of patients: -- Patients with either degenerative or functional MR. -- Patients who are good surgical candidates and are open to the option of a less invasive approach. -- High risk patients ...