Death in Medical Technology

New Therapy Found to Prevent Heart Failure

... a 29 percent reduction in heart failure or death in patients with heart disease who received an ... point - significant reduction in heart failure or death with CRT-D versus ICD-only. Cardiologist Arthur ... failure. "Now we can prevent sudden cardiac death and inhibit the development of heart failure, ...

Large, Long-Term Study Shows Avandia Has No Increased Overall Cardiovascular Risk Compared to Other Commonly Used Diabetes Medicines

... cardiovascular hospitalization and cardiovascular death are similar in patients taking Avandia ... cardiovascular hospitalization or cardiovascular death (which includes heart attack, congestive heart ... no increased risk of overall cardiovascular death or hospitalization compared to the most commonly ...

Results and Additional Analyses From Study Show That Corthera's Relaxin for Acute Heart Failure is the Strongest Predictor of Improved Longer-Term Outcomes Following Hospital Discharge When Compared to Other Variables

... two outcome measures: 60-day cardiovascular (CV) death or re-admission for heart failure and 180-day CV ... treatment was the strongest predictor of less CV death or heart failure re-admission (p<0.01). Blood ... and univariate analyses predicting CV death at 180 days. "These new analyses, when added ...

Boston Scientific Welcomes Results of Brain Aneurysm Clinical Trial

... Risk of death at five years is lower for aneurysm patients ... The latest ISAT data assessed the risk of death and re-bleeding after treatment in more than ... a 23 percent relative reduction in risk of death for coiled patients. The percentage of patients ...

RISPERDAL(R) CONSTA(R) (Risperidone) Long-Acting Treatment Delayed the Time to Relapse in Patients with Bipolar I Disorder

... antipsychotic drugs are at an increased risk of death compared to placebo. RISPERDAL(R) CONSTA(R) ... atypical antipsychotic drugs, revealed a risk of death in the drug-treated patients of between 1.6 to 1.7 times the risk of death in placebo-treated patients. Over the course of a ...

New MADIT II Clinical Data Analysis Shows Long-Term Survival Benefit for Implantable Defibrillator Therapy

... A 41 percent relative reduction in the risk of death for ICD patients at four years A 37 percent relative reduction in the risk of death for ICD patients at eight years ... that ICD therapy reduced the relative risk of death by 31 percent at 20 months follow-up. "ICD ...

Paloma Pharmaceuticals Presents at the Association for Research in Vision and Ophthalmology 2009 Meeting

... the Akt/mTOR Pathway Reduces Photoreceptor Cell death Following Experimental Retinal Detachment", today ... administered Palomid 529 slows photoreceptor cell death following retinal detachment in a seven day ... deficits may be permanent, and related to the death of photoreceptor cells, the cells responsible for ...

Video: Afinitor(R) Approved in US as First Treatment for Patients With Advanced Kidney Cancer After Failure of Either Sunitinib or Sorafenib

... and reduced the risk of disease progression or death by 67% compared with placebo - Only ... than doubled the time without tumor growth or death in patients with advanced kidney cancer (4.9 vs. ... and reduced the risk of disease progression or death by 67% (hazard ratio=0.33 with 95% confidence ...

Schering-Plough Announces Results of the Early ACS Trial

... through 96 hours. The secondary endpoint was death or (re)MI at 30 days. Safety endpoints included ... provisional group (p=0.23). At 30 days, the death or (re)MI rate for the study group was 11.2 ... The key secondary efficacy endpoint was 30-day death or (re)MI. Safety endpoints included rates of ...

Abbott's Market-Leading XIENCE V(R) Shows Increasing Clinical Advantages Over TAXUS(R) Express2(TM)/TAXUS(R) Liberte(TM) Between Two and Three Years

... an 88 Percent Reduction in the Risk of Cardiac death at Three Years ORLANDO, Fla., March 29 ... market-leading XIENCE V maintained a low cardiac death rate of 0.5 percent, while the observed cardiac death rate for TAXUS more than tripled during the same ...

Parkinson's Disease Foundation Awards $300,000 in Bridge Funding for Innovative Research Projects

... clumping is believed to contribute to the cell death that leads to Parkinson's. Their team will test ... by an immune response, plays in causing the death of neurons in Parkinson's. Scientists already ... share a common mechanism that contributes to the death of neurons. He hypothesizes that this mechanism ...

New England Journal of Medicine Publishes Results From the Landmark ATHENA Trial with Multaq(R) (dronedarone) in Atrial Fibrillation

... the risk of cardiovascular hospitalization or death by 24 percent in patients with atrial ... risk of first cardiovascular hospitalization or death by 24 percent (31.9% vs. 39.4%, p<0.001) in ... decrease in the risk of cardiovascular death by 29 per cent (p=0.03) in patients with AF. ...

Video: Zometa(R) Reduces Risk of Breast Cancer Recurrence in Premenopausal Women, Study in The New England Journal of Medicine Reports

... therapy reduced risk of breast cancer return or death by 36% more than hormone therapy alone - ... provided a reduction in risk of recurrence or death that was 36% beyond that achieved with hormone ... distant metastasis, secondary carcinoma and/or death from any cause. Recurrence-free survival was ...

ASGE Urges Patients to Seek a Qualified Endoscopist Before Undergoing a Colonoscopy for Colorectal Cancer

... finds that colonoscopy is associated with lower death rates, but raises concerns about detection of ... found that colonoscopy is associated with lower death rates from colorectal cancer, however, the ... in the recent decline in the incidence and death rates from colorectal cancer announced last month ...

Video: Femara(R) First Aromatase Inhibitor to Indicate Survival Benefit Versus Tamoxifen When Taken for Five Years After Breast Cancer Surgery

... - Femara showed reduced risk of death by 13% (P=0.08), despite inclusion of patients ... they crossed over to Femara, reduction in risk of death was 19% - Long-term follow-up from major ... In this analysis, a 19% reduction in risk of death (HR=0.81, 95% CI: 0.69-0.94) was observed in ...

Dronedarone (Multaq(R)) Reduced the Incidence and Duration of Hospitalization in Patients with Atrial Fibrillation

... of CV hospitalization or death was 26% lower for those receiving dronedarone ... endpoint of cardiovascular hospitalization or death even in patients with permanent AF, suggesting ... of cardiovascular hospitalization or death from any cause by a statistically significant 24 ...

Study Showed Prevention of Heart Attacks Within Three Months After Hospitalization Significantly Averted Future Heart Attacks and Death

... more likely to have an additional heart attack or death within four years. The increased rate of heart attack and death among patients who had a heart attack remained ... more likely to suffer a recurrent heart attack or death over a four-year period compared with those who ...

Atrial Fibrillation Found to be Common in Patients With Atherothrombosis, Increases Risk of Cardiovascular Death, Heart Attack and Stroke

... for atherothrombotic disease, the risk for death and non-fatal cardiovascular outcomes was greater ... including more than twice as high for CV death (3.2% vs 1.4%; p<0.0001), 87% higher for death from all causes (4.3% vs. 2.3%, p<0.0001), 50% ...

Taxus Atlas Studies Reinforce Safety and Efficacy of Boston Scientific's Next-Generation Taxus Liberte Stent

... data also showed comparable rates of cardiac death (3.4 percent for the TAXUS Liberte Stent vs. 2.3 ... Stent (p=0.76). The composite measure of cardiac death or MI showed a significant 63 percent reduction ... percent vs. 9.4 percent, p=0.0426). All cause death was reported as 2.8 percent for the TAXUS Liberte ...

NVA237 Phase II Results Presented at the European Respiratory Society Annual Meeting Show Promising Efficacy and Tolerability With Potentially Faster Onset Than Tiotropium

... and is projected to be the third leading cause of death by 2030. It is a progressive lung disease ... COPD is currently the fourth most common cause of death and by 2030 is predicted to become the third most common cause of death and the fourth most important disability ...

Quark Pharmaceuticals Announces First RNAi Drug Candidate Having a Novel, Proprietary Structure Covered by Quark Intellectual Property

... in a model of retinal ganglion cell (RGC) death by optic nerve crush (ONC). In a second study of ... its effectiveness was examined in a model of RGC death induced by axotomy of the optic nerve. QPI-1007 ... degeneration and reduced injury induced RGC death in vivo, the hallmarks of glaucoma and acute ...

Further Analysis From ATHENA Study Showed That Multaq(R) (dronedarone) Reduced the Risk of Stroke in Patients With Atrial Fibrillation

... of the risk of cardiovascular hospitalizations or death from any cause by a statistically significant 24% ... of atrial fibrillation, and a major cause of death and long-term disability, these new results ... The pre-specified secondary endpoints were death from any cause, cardiovascular death and ...

Further Analysis From ATHENA Study Showed That Multaq(R)(Dronedarone) Reduced the Risk of Stroke in Patients With Atrial Fibrillation

... of atrial fibrillation, and a major cause of death and long-term disability, these new results ... The pre-specified secondary endpoints were death from any cause, cardiovascular death and ... cause of cardiovascular hospitalizations or death in this patient population. About Multaq(R) ...

SCAI: SYNTAX Data Show PCI Is a Good Option for Patients With Complex Coronary Artery Disease

... drug-eluting stents had rates of heart attack and death no different from bypass surgery after one year. ... are just as safe for them as surgery in terms of death or heart attack," says Dr. Ted Feldman, SCAI Past ... statistically significant difference in risk of death (4.3% vs. 3.5%, respectively; p=0.37) or heart ...

Intercell Announces Initiation of Further Phase II Clinical Trial of V710 an Investigational Vaccine to Prevent S. aureus Infection

... caused by bacteria are one of the major causes of death and serious illness. Intercell has embarked on a ... are leading to serious health complications, death and economic burden. Today, approximately 50% of ... infections are one of the major causes of death and serious illness worldwide, resulting in an ...

Head-to-Head Study Showed Prasugrel Statistically Superior to Clopidogrel in Reducing Recurrent Cardiovascular Events

... recurrent heart attack, stroke or cardiovascular death after first event than those taking clopidogrel ... taking clopidogrel.(1) The risk of cardiovascular death overall in the study was not statistically ... group. -- The risk of cardiovascular death after a heart attack while on therapy was ...

Wyeth Applauds Six Countries Across Europe, and the Middle East, That Recently Announced the Inclusion of the 7-Valent Pneumococcal Conjugate Vaccine (PCV7) in Their Immunization Schedules

... Against the Leading Vaccine-Preventable Cause of death in Young Children Wyeth applauds the countries ... is the leading vaccine-preventable cause of death in children younger than five years of age ... and adults and is a leading cause of illness and death worldwide(6). Pneumococcal disease is caused ...

The Largest Ever Study of Diabetes Shows Intensive Glucose Control Reduces Serious Complications

... disabling consequences of diabetes, leading to death in one in five people with diabetes." ... evidence whatsoever of any increased risk of death among those receiving intensive treatment in ... reduction in the risk of cardiovascular death (12%), although not statistically significant. ...

Heart Patients More Likely to Adopt Healthy Habits in 3-Year Program Led by Cardiac Rehabilitation Experts, Mayo Clinic Research Shows

... model of care versus traditional care had a lower death rate. While larger studies will need to ... died, (25 men and four women), an annual death rate of 1.9 percent. This compares to the Centers ... Disease Control and Prevention's expected annual death rate of 1.6 percent for Americans of comparable ...

Video: Major Independent Trial Demonstrates Significant Anticancer Benefit of Zometa(R) in Women With Early-Stage Breast Cancer

... reduced the risk of cancer returning or death by 36% beyond clinical benefits ... of disease-free survival events (which include death from any cause) fell by 36% (P=0.01), compared to ... distant metastasis, secondary carcinoma, and/or death from any cause. Recurrence-free survival was ...

New Eloxatin(R) (oxaliplatin injection) Prescribing Information in the U.S. Includes Six-Year Overall Survival Data

... Results Showing a 20% Reduction in the Risk of death at Six Years and a 22% Improvement of Disease ... regimen significantly lowered the risk of death and recurrence," said principal investigator ... is the third leading cause of cancer-related death in the U.S., accounting for about 10% of all ...

ATHENA Clinical Results with Dronedarone (Multaq(R)) Highlighted at the World Cardiology Congress

... death, as well as a 45% reduction in arrhythmic death or 30% cardiovascular death, dronedarone may ... by preventing cardiovascular hospitalizations or death from any cause. The study included 4,628 ... The pre-specified secondary endpoints were death from any cause, cardiovascular death and ...

ATHENA Clinical Results for Dronedarone (Multaq(R)) Highlighted at the World Cardiology Congress

... death, as well as a 45% reduction in arrhythmic death or 30% cardiovascular death, dronedarone may ... by preventing cardiovascular hospitalisations or death from any cause. The study included 4,628 ... The pre-specified secondary endpoints were death from any cause, cardiovascular death and ...

New Roche Data to be Presented at ASCO Offers Further Hope for Cancer Patients

... inhibit cancer cell growth and ultimately lead to death of cancer cells. Colorectal cancer -- ... of breast cancer are diagnosed(2) with a death rate of over 500,000 people per year.(3) -- ... and the second most common cause of death from cancer across all cancer types in men ...

Landmark ATHENA Study Findings With Multaq(R) (dronedarone) Shows 24% Reduction In Cardiovascular Hospitalization or Death in Patients With Atrial Fibrillation

... the risk of cardiovascular hospitalizations or death from any cause by a statistically significant 24% ... in the risk of cardiovascular death by 30% (p=0.03) on top of standard therapy, ... decreased the risk for arrhythmic death by 45% (p=0.01), and there were numerically less ...

Report on 750 New Medicines in Development for Cancer Released in Baton Rouge

... Control and Prevention, Louisiana has the highest death rate from cancer in the United States. In fact, ... men in Louisiana have the highest death rate and shortest survival rate in the country ... a new treatment that brought me from the brink of death back to life." Cancer medicines being ...

Cardium's Innercool Therapies Unit Announces Publication of Positive Effects of Early and Rapid Hypothermia Following Heart Attack

... myocardial reperfusion injury can result in the death of cardiac tissue that was viable immediately ... intended to cool patients in order to reduce cell death and damage caused by ischemic events in which ... to protect endangered cells, prevent tissue death and preserve organ function following acute ...

Bionovo Announces Publication of the Paper Detailing the Mechanism of Action of Its Cancer Drug BZL101

... advanced breast cancer. "BZL101 induces cell death in breast cancer cells but not in normal breast ... is a key factor in the energetic collapse and death that occurs selectively in breast cancer cells, ... glycolysis. This leads to DNA damage and cell death in cancer cells while normal cells remain ...

Landmark ONTARGET(TM) Trial Demonstrates Micardis(R) is Equally Effective as Ramipril, with Fewer Discontinuations, in a Broad High-Risk Cardiovascular Population

... disease (CVD) is the number one cause of death and disability globally(4) and is responsible for ... diseases to become the largest cause of death and disability worldwide.(7) It is ... cardiovascular disease -- the number one cause of death worldwide. Boehringer Ingelheim has introduced ...

Universite de Montreal Researchers Simulate World's Largest Heart Model Using SGI Technology

... With heart disease one of the leading causes of death in the Western world, discovering the electrical ... and "Long-QT syndrome" which can cause sudden death in young, otherwise healthy people, and there are ... the typical ECG and the risk of sudden cardiac death that are linked with Brugada syndrome. However, ...