Cytology in Medical Technology

Hologic Releases the Results of the Cervista(TM) HPV Clinical Trials

... as a general screen, in combination with cervical cytology (pap test), to help guide patient management for ... years of age or older, and as a triage for ASC-US cytology results to determine the need for referral ... cellularity. -- Small volume of liquid-based cytology sample required for HPV testing. Hologic believes ...

University of Michigan Study Shows SEQUENOM's MassARRAY Technology Identifies HPV Infections Missed by Standard Hybridization Test

... research studies show that the test can measure and reproducibly detect as few as 50 DNA copies for each of the 15 HPV genotypes in liquid cytology samples from cervical smears and tissue biopsy samples. The AttoSense test is currently available for Research Use Only. SEQUENOM intends to seek ...

Study Finds QIAGEN's HPV Test Offers Greater Long-term Protection From Cervical Disease Than the Pap

... (HPV) DNA test are half as likely to develop moderate to severe cervical disease over the next six years as those who get only conventional cytology (the Pap "smear"). The research followed nearly 3,000 women age 35 years and older, and assessed their HPV status using QIAGEN's digene(R) HPV Test - ...

CERVARIX(R) Shown to Provide Longest Duration of Sustained Neutralizing Antibodies to Date

... In the extended follow-up study, women were evaluated for the presence of human papillomavirus DNA by PCR using cervical samples and annual cervical cytology evaluations were performed. Women were referred for colposcopy following protocol guidelines. Women were also assessed for long-term immunogenicity ...

GSK Cervical Cancer Candidate Vaccine CERVARIX (R) Demonstrates Long-Term Protection for More Than Six Years

... et al. Preferential risk of HPV16 for squamous cell carcinoma and of HPV18 for adenocarcinoma of the cervix compared to women with normal cytology in The Netherlands. Br J Cancer. 2006;94:171-175. (6) Liu S, Semenciw R, et al. Cervical cancer: the increasing incidence of ...

Helix BioPharma Corp. Announces Positive Phase II Clinical Results with its Topical Interferon Alpha-2b

... with resolution of their abnormal Pap smear LSIL cytology to normal during the 12 week study duration. Pap ... Of these women, one treated patient's LSIL cytology returned following the end of treatment, which ... to the North American definition of LSIL cytology (i.e., "The Bethesda Classification System"), the ...

Testing for Human Papillomavirus

... include standard Papanicolaou (Pap) test cytology in conjunction with newer HPV DNA diagnostic ... HPV-positive women with negative or borderline cytology can be monitored by repeat testing, thereby ... is not recommended; however, screening by anal cytology and anoscopy may be beneficial among the ...

DNA Therapeutics Reports a Novel Mechanism of Action and a Biomarker of its Lead Molecule Dbait That Open an Innovative Pathway-Targeting in Molecular Cancer Therapy

... lines treated by intra-tumoral injection of Dbait, in association with radiotherapy, is significantly increased in a dose-dependent manner. MRI and cytology analysis of tumors shows that Dbait strongly enhances irradiation-induced necrosis and apoptosis. New finding: The present study aims at ...

Cervarix, GSK Cervical Cancer Candidate Vaccine, Demonstrates 100 Percent Protection Against Precancerous Lesions Caused By Cancer-Causing Human Papillomavirus Types 16 & 18 for More Than Five Years

... In the extended follow up study, women were evaluated for the presence of human papillomavirus DNA by PCR using cervical samples and annual cervical cytology evaluations were performed. Women were referred for colposcopy following protocol guidelines. Women were also assessed for long-term immunogenicity ...

Largest Cervical Cancer Vaccine Efficacy Trial Shows Cervarix Provides Excellent Protection Against Lesions Caused by Most Common Cancer-Causing Virus Types

... of 15 months after first vaccination, in which a proportion of the women enrolled already had a human papillomavirus infection or abnormal cytology (abnormal Pap smears) at study entry. The primary objective of the interim analysis was to evaluate the vaccine efficacy against precancerous ...