Schering-Plough Announces U.S. Filing of Mometasone Furoate/Formoterol Fumarate Combination for the Maintenance Treatment of Asthma
...
Combination products containing inhaled
corticosteroids and long-acting beta2-agonists are the largest ... the growth of children and adolescents taking
corticosteroids by any route, and reduce each patient's dose to ... AEROLIZER is not a substitute for inhaled or oral
corticosteroids and, in the treatment of asthma, they should not ...
PARI Pharma's Nebulized DSCG Shows Results Similar to Inhaled Steroids in Asthma Studies Presented at ATS
... disodium cromoglycate (DSCG) solution, to inhaled
corticosteroids (ICS) in 28 children with atopic asthma. Results ... eFlow Nebulizer System, or inhaled
corticosteroids (ICS) without dose adjustments administered in ... the six-month treatment with either inhaled
corticosteroids or IsoCrom.
PARI's Comparative in-vitro ...
Emerging Therapies Could Help Ease The Chronic Symptoms of Atopic Dermatitis For Adults and Children
... for patients of all ages."
Topical
corticosteroids
Used to diminish the skin's inflammatory response, topical
corticosteroids are a mainstay in the treatment of atopic dermatitis. Now, newer formulations of topical
corticosteroids in gels, foams and oils, which have undergone ...
Study Results Show Epratuzumab Provided Clinically Meaningful Reduced Disease Activity in Patients With Lupus
... 720mg/m2 patients achieved tapering of
corticosteroids compared
to 57 percent of placebo. Epratuzumab ... 360mg/m2, n=14, 720mg/m2,
n=5, placebo, n=13).
corticosteroids were increased at baseline. Disease
activity ... in
immunosuppressives and/or anti-malarials or
corticosteroids above baseline
or tapering levels.
UCB has ...
AstraZeneca Submits an sNDA for SYMBICORT(R) for the Treatment of Asthma in Children as Young as Age Six
... is not adequately controlled with inhaled
corticosteroids alone."
The submission package is based on a ... controlled with medium
doses of inhaled
corticosteroids alone.(10) The annual direct healthcare
cost of ... Asthma Previously Treated with Inhaled
corticosteroids (ICSs) [poster]. American Thoracic ...
Steroids Provide No Survival Benefit for Children With Bacterial Meningitis
... PHILADELPHIA, May 6 /PRNewswire-USNewswire/ --
corticosteroids given to
children who are hospitalized for ... adults,
physicians have increasingly been using
corticosteroids in children with
bacterial meningitis," said ... discharge, between children who received
corticosteroids and those
who did not. Overall, unadjusted ...
Inhaled Steriods Used as Preventive Treatment Post 9/11
... CHICAGO, Oct. 24 /PRNewswire/ -- Inhaled
corticosteroids (ICS),
antiinflammatory treatments often ... data
suggest that combining prophylactic inhaled
corticosteroids with our best
attempts to provide proper ... of AstraZeneca, and the use of inhaled
corticosteroids may be
considered off- label use. The sponsors ...
New Study Suggests Cholesterol-Lowering Statins Reduce Severe Asthma Attacks that Result in Hospitalizations and Emergency Room Visits
... Patients on
corticosteroids are one-third less likely to need emergency room treatment or ... drug therapies for treating asthma include the long-term use of inhaled
corticosteroids to reduce airway inflammation and mucus production.
Statins are ...
AstraZeneca Responds to FDA Joint Advisory Committees' Recommendation on SYMBICORT(R)
... be used in patients whose asthma can be successfully managed by inhaled
corticosteroids along with occasional use of inhaled short-acting beta2-agonists. ... occurred in asthmatic patients during and after transfer from systemic
corticosteroids to less systemically available inhaled corticosteroids.
Patients ...
Pivotal Data Showed SYMBICORT(R) Improved Lung Function in Adults with COPD
... COPD.(1,2) After two weeks
of treatment based on previous therapy (inhaled
corticosteroids (ICS) and
short-acting bronchodilators were allowed), patients were then ... indicated in patients whose asthma can be successfully
managed by inhaled
corticosteroids along with occasional use of inhaled
short-acting beta2- agonists.(6) ...
Continuous Treatment With Abbott's HUMIRA(R) Achieves Superior Long-Term Efficacy for Psoriasis Patients Compared to Interrupting Treatment
... HUMIRA can be given as monotherapy in case of intolerance
to
corticosteroids or when continued treatment with
corticosteroids is
inappropriate.
HUMIRA is indicated for the treatment of moderate to ...
Study Analyzed SYMBICORT(R) in Children with Persistent Asthma
... (BUD/FM pMDI) in Children With Asthma Previously Treated With Inhaled
corticosteroids (ICSs) [poster]. American Thoracic Society, May 16-21, 2008, Toronto. ... (BUD/FM pMDI) in Children With Asthma Previously Treated With Inhaled
corticosteroids (ICSs) [poster]. American Thoracic Society, May 16-221, 2008, Toronto. ...
New Data Shows Veramyst Effectively Treats Symptoms of Perennial Allergic Rhinitis
... more about prescription Veramyst,
talk to your doctor. About Intranasal
corticosteroids The way intranasal
corticosteroids (INSs) work is not fully understood
but by acting early and throughout the ...
July 2009 Mayo Clinic Health Letter Highlights a Positive Outlook, Bell's Palsy and Heart Valve Repair
...
Treatment increases the likelihood of full recovery and may help shorten the recovery time. A doctor may prescribe a course of oral
corticosteroids to help reduce inflammation around the facial nerve.
Researchers have studied antiviral drugs as a way to speed recovery. There's some ...
ASMANEX(R) (Mometasone Furoate Dry Powder Inhaler) Now Approved in Japan for the Treatment of Bronchial Asthma in Adult Patients
... The long-term effect on final adult height is unknown. Health care providers should closely follow the growth of children and adolescents taking
corticosteroids by any route, and reduce each patient's dose to the lowest dose that effectively controls his/her symptoms.
ASMANEX may increase the risk of ...
DOR BioPharma Receives EMEA Agreement on the Design of its Confirmatory Phase 3 Clinical Trial of orBec(R) in GI GVHD
... ability to provide clinically meaningful outcomes when compared with the current standard of care, including a lowered exposure to systemic
corticosteroids following allogeneic transplantation. Currently, there are no approved products to treat GI GVHD. The first trial was a 60-patient Phase 2 ...
Video: Data on More Than 15 Novartis Oncology Compounds at ASCO Highlight Progress Toward Targeted Therapies for Diverse Tumor Types
... Several postmarketing reports describe patients able to tolerate the reintroduction of Gleevec at a lower dose with or without concomitant
corticosteroids or antihistamines following resolution or improvement of the bullous reaction.
Consider potential toxicities-specifically liver, kidney, and ...
Pivotal Data Show Bronchial Thermoplasty Can Improve Quality of Life and Reduce Asthma Attacks and Emergency Room Visits for Adults with Severe Asthma
... in adult patients with severe asthma who were symptomatic, despite being treated with high doses of standard of care medications (high dose inhaled
corticosteroids and long-acting bronchodilators). The study was a randomized, double-blind, sham-controlled trial and enrolled 297 patients at 30 sites in 6 ...
Video: Partnership Unites UCB with Consumer Product Innovator OXO(R)
... These adverse reactions occurred more frequently among patients with a baseline history of hypertension and among patients receiving concomitant
corticosteroids and non-steroidal anti-inflammatory drugs. Patients receiving CIMZIA 400mg as monotherapy every 4 weeks in RA controlled clinical trials had similar ...
ADVENTRX Announces Results From ANX-514 Bioequivalence Study
... On Day 1, patients were dosed with either ANX-514 or Taxotere and, on Day 22, were dosed with the other drug. Patients were premedicated with
corticosteroids prior to treatment on Day 1 and on Day 22. The FDA has indicated that this single bioequivalence study, should it demonstrate pharmacokinetic ...
American Lung Association Study to be Published in the 'New England Journal of Medicine' Finds Prescription Heartburn Medication Does Not Control Asthma Symptoms as Previously Thought
... without GER symptoms can substantially improve asthma control.
Methods: 402 asthmatics with inadequate asthma control despite inhaled
corticosteroids and absent or minimal GER symptoms were randomly assigned to either esomeprazole 40 mg b.i.d. or matching placebo in a parallel-group double-masked ...
Aerovance Initiates Phase IIb Clinical Trial with Aerovant(TM) for the Treatment of Uncontrolled Asthma
... approximately 500 patients with moderate to severe asthma, in the United States and Europe, who are poorly controlled by the combination of inhaled
corticosteroids (ICS) and long-acting beta agonists (LABA). Patients will be randomly assigned to receive one of three Aerovant doses (1 mg, 3 mg or 10 mg) or ...
Nplate(R) Approved in the European Union for the Treatment of Chronic Immune (Idiopathic) Thrombocytopenic Purpura (ITP)
... groups when treated with Nplate. Additionally, patients treated with Nplate were able to reduce or discontinue concomitant medications such as
corticosteroids which are often not well tolerated. Nplate patients also used far less "emergency" medications such as IVIG and Win-Rho, whose effects are transient. ...
Cephalon Signs Option Agreement to Acquire Ception Therapeutics
... as vomiting, epigastric or chest pain, dysphagia, and food impaction. There are no approved pharmacologic therapies specifically for EE, although
corticosteroids sometimes are administered to patients.
About Cephalon, Inc.
Founded in 1987, Cephalon, Inc. is an international biopharmaceutical ...
Video: Tasigna(R) Demonstrates Rapid Response as Initial Therapy in Life-Threatening Form of Leukemia
... Several post marketing reports describe patients able to tolerate the reintroduction of Gleevec at a lower dose with or without concomitant
corticosteroids or antihistamines following resolution or improvement of the bullous reaction.
Consider potential toxicities-specifically liver, kidney, and ...
First Clinical Experience With Soliris(R) in Treating Patients With Two Rare Complement-Mediated Diseases Presented at ASH Annual Meeting
... by the production of circulatory cold agglutinins, a type of
monoclonal antibody that lead to hemolysis. Conventional treatments for CAD,
including
corticosteroids and immunosuppressive drugs, are ineffective in many
patients.
"We currently lack effective treatment options for patients with CAD,"
noted ...
More Than 200 Abstracts at ASH and SABCS Reveal Potential Compelling Patient Benefits From Novartis Oncology Current and Pipeline Therapies
... Several post-marketing reports describe patients able to tolerate the reintroduction of Gleevec at a lower dose with or without concomitant
corticosteroids or antihistamines following resolution or improvement of the bullous reaction.
Consider potential toxicities--specifically liver, kidney and ...
Study Found That Long Term Use of Advair Diskus(R) 250/50 Did Not Adversely Affect Bone Loss in Patients with COPD
... bone loss," said Richard ZuWallack, MD of St. Francis
Hospital and Medical Center, Hartford CT. "These data inform on the
long-term impact of inhaled
corticosteroids on bone mineral density."
About the Study
Effects of treatment with Advair Diskus 250/50 or salmeterol 50 mcg on
BMD were evaluated in 186 ...
CIMZIA(R) (Certolizumab Pegol) Provides Rapid and Sustained Relief from Signs and Symptoms of Rheumatoid Arthritis for Two Years
... function of the
affected joints to prevent disability.
Traditional treatments for RA include nonsteroidal anti-inflammatory
drugs (NSAIDs),
corticosteroids and disease-modifying antirheumatic drugs
(DMARDs), with biological therapies a more recent addition. Anti-TNF
(TNF-alpha; Tumor Necrosis Factor) ...
Early Data Show Potential for Imatinib Mesylate Tablets to Treat Life-Threatening Form of Pulmonary Artery Disease
... Several postmarketing reports describe
patients able to tolerate the reintroduction of Gleevec at a lower dose
with or without concomitant
corticosteroids or antihistamines following
resolution or improvement of the bullous reaction.
Consider potential toxicities--specifically liver, kidney and ...
CIMZIA(R) (Certolizumab Pegol) Provides Long-Term Benefit Without Dose Escalation in Crohn's Disease Patients
... and scores of >450 indicate severe illness along the
600 point scale.
Response to CIMZIA was similar when used as a monotherapy or with
concomitant
corticosteroids or immunosuppressants. There were also no
differences in clinical responses to CIMZIA among those patients who had
previously lost response to ...
Video: Sirion Therapeutics Launches Durezol for Postoperative Ocular Inflammation and Pain
... diseases of the cornea and conjunctiva, and also in fungal
infections or mycobacterial infections of the eye or ocular structures.
Prolonged use of
corticosteroids may increase the hazard of secondary
ocular infections, exacerbate the severity of ocular viral infections, and
increase the development of fungal ...
CellCept(R) and a Reduced Level of CNI Shows Trend Towards Preservation of Kidney Function Versus a Standard-Dose CNI
... CellCept and the standard level of CNI, or a
fixed-dose of CellCept and the standard level CNI.
Antibody induction and/or
corticosteroids were administered according
to center practice. Primary endpoints were the proportion of patients with
treatment failure (BPAR, graft loss, and ...
New Data Show TORISEL Improves Progression-Free Survival for Patients With Relapsed/Refractory Mantle Cell Lymphoma
... Some patients were asymptomatic and others presented with
symptoms. Some patients required discontinuation of TORISEL and/or
treatment with
corticosteroids and/or antibiotics.
Cases of fatal bowel perforation occurred with TORISEL. These patients
presented with fever, abdominal pain, metabolic ...
New Analyses Presented at ASCO Reaffirmed Efficacy and Safety of TORISEL in Patients With Advanced Kidney Cancer
... Some patients were asymptomatic and others presented with
symptoms. Some patients required discontinuation of TORISEL and/or
treatment with
corticosteroids and/or antibiotics.
Cases of fatal bowel perforation occurred with TORISEL. These patients
presented with fever, abdominal pain, metabolic ...
Wyeth Initiates INTORACT -- A New Clinical Trial to Examine TORISEL Plus Avastin for First-Line Treatment of Advanced Kidney Cancer
... occurred. Some patients were asymptomatic and
others presented with symptoms. Some patients required discontinuation of
TORISEL and/or treatment with
corticosteroids and/or antibiotics. Cases of
fatal bowel perforation occurred with TORISEL. These patients presented
with fever, abdominal pain, metabolic acidosis, ...
Novagali Pharma Successfully Enrolls First Patient in U.S. Phase I Clinical Study with CORTIJECT(R) for Diabetic Macular Edema
... Martinez, Pharm.D., Novagali Pharma Chief Executive Officer. "Thanks
to EYEJECT(R) technology, CORTIJECT(R) is a major move with the optimized
use of
corticosteroids for the back of the eye expected to combine ease of
use, sustained release and ocular safety. Administering this emulsion
through a single injection ...
New Trial Presented at AAAAI Reports that the Growth of Children 2-5 Years Old with Year-Round Allergic Rhinitis Continued According to Normal Age-Adjusted Distribution Over a 6-Month Treatment with Nasacort AQ
... treatment effect
on stature-for age distribution among children aged 2-5 years old with
year-round allergic rhinitis.
"Continuous use of intranasal
corticosteroids in the treatment of very
young children with allergic rhinitis has in the past raised concerns
regarding potential effects on growth," said study ...
Ception Therapeutics Initiates Phase II/III Clinical Trial for Its Lead Product Reslizumab in Eosinophilic Esophagitis (EE) in Children
... elemental formula diet typically administered by nasogastric
or gastrostomy tube.(2) There are no approved pharmacologic therapies for
EE, although
corticosteroids are sometimes administered to patients.
About Ception Therapeutics, Inc.
Ception Therapeutics is a biopharmaceutical company focused on ...
Osteoarthritis: Which Treatments Work and Which Don't?
... and selective oral nonsteroidal anti-inflammatory drugs (NSAIDs) (93%); topical NSAIDs and capsaicin (85%); intraarticular injections of
corticosteroids (78%); intraarticular injections of hyaluronans (64%); glucosamine and/or chondroitin sulphate for symptom relief (63%); glucosamine ...