Pixantrone Produces High Rates of Complete and Partial Remissions Even Among Aggressive NHL Patients With Extensive Prior Doxorubicin Treatment or Prior Rituximab Treatment
... fraction (LVEF) and only one patient developed
congestive heart failure (CHF). The total cumulative ... cardiac disorders included cardiac arrest,
congestive heart failure, myocardial infarction, cyanosis, ... cause cumulative heart damage that may result in
congestive heart failure many years later. As a result, ...
MitraClip(R) Therapy Data Demonstrate Clinical Benefit in High-Risk Patients With Mitral Regurgitation
... Function and Reduced rate of Hospitalization for
congestive Heart Failure in both Functional and Degenerative ... function and reduced hospitalization for
congestive heart failure for both MR groups at twelve ... for both groups. The rate of hospitalization for
congestive heart failure in the year after treatment with ...
Study Finds DOXIL(R) Combination Therapy Delays Disease Progression for Patients With Metastatic Breast Cancer
... Grade 2 cardiac
adverse events). Symptomatic
congestive heart failure was reported in 1% of
subjects in ... toxicity. Myocardial damage may
lead to
congestive heart failure and may occur as the total ... function should be carefully monitored
-
congestive heart failure or cardiomyopathy may occur after
...
Video: Answer to Curing a Failing Heart May Exist in Body's Own 'Do-It-Yourself' Repair Kit
... (AHI) is paving the way for how to treat
congestive heart
failure (CHF) patients.
To view the ... research studies in patients
suffering from
congestive heart failure (CHF), the first in 2002 ... a patient may be able to
heal their own heart."
congestive Heart Failure is a condition in which the heart ...
Bioheart Announces 35 Leading U.S. Heart Failure Centers Engaged in Phase II/III Marvel Trial of Myogenic Cells for Treating Advanced Heart Failure
... with no additional therapeutic
options.
ABOUT
congestive HEART FAILURE
congestive heart failure (CHF), or heart failure, is a ... Implantation by a Catheter Delivery
System in
congestive Heart Failure Patients Post-Myocardial ...
n-3 PUFAs Reduce Mortality and Hospital Admissions in Patients With Symptomatic Heart Failure
... 6% (p=0.049) Admission to hospital for
congestive 6% (p=0.147) heart failure ... we have seen a number of large outcome trials in
congestive heart
failure using a variety of approaches. ... this treatment to the established therapies of
congestive heart
failure."
References
1. GISSI-HF ...
TRANSCEND(TM) Trial Results Presented at European Society of Cardiology Congress and Published in The Lancet
... infarction, stroke and hospitalization for
congestive heart failure in ACE
inhibitor intolerant ... infarction, stroke and hospitalization for
congestive heart
failure. This reduction was not ... infarction, stroke
and hospitalization for
congestive heart failure, and resulted in ...
Bioheart Reports Promising Results From SDF-1 Modified MyoCell(R) Therapy in Heart Failure Study
... of using autologous myoblasts in the treatment of
congestive heart
failure and opens the possibility of ... in future
treatment for patients suffering from
congestive heart failure. Bioheart
obtained a worldwide ... MARVEL is currently enrolling NYHA Class II-IV
congestive heart
failure patients in approximately 25 of the ...
ATHENA Clinical Results for Dronedarone (Multaq(R)) Highlighted at the World Cardiology Congress
... and no excess of
hospitalisations for
congestive heart failure. There was a similar rate of
study ... and
cardiovascular complications, including
congestive heart failure.
ATHENA, was the largest double ... lead to serious complications, such as
stroke and
congestive heart failure.
AF is a condition in which the ...
Palatin Technologies Initiates Phase 2 Hypertension Clinical Study With PL-3994
... PL-3994 for the treatment of acute
decompensated
congestive heart failure and plans to initiate a ... treatment
in an acute care setting.
About
congestive Heart Failure (CHF)
Currently in the U.S., CHF ... over 1,100,000 hospitalizations for CHF in
2004.
congestive heart failure has tremendous human and financial ...
Landmark ATHENA Study Findings With Multaq(R) (dronedarone) Shows 24% Reduction In Cardiovascular Hospitalization or Death in Patients With Atrial Fibrillation
... and cardiovascular complications, including
congestive heart
failure. Furthermore atrial fibrillation ... to placebo and no excess
of hospitalizations for
congestive heart failure. There was a similar rate
of study ... lead to serious complications, such as
stroke and
congestive heart failure.
AF is a condition in which the ...
Wayne State University and Oakwood Partner in New Device to Combat Congestive Heart Failure
... implanted a new device designed to combat
congestive heart
failure in a 49-year-old patient. The ... man, was suffering from an advanced
stage of
congestive heart failure.
Surgeons said the patient is ... function of the heart, and
potentially preventing
congestive heart failure from advancing by reversing
the ...
Final Data From the Bioheart Seismic Trial Suggest Safety, Efficacy of Autologous Stem-Cell Therapy for Treating Congestive Heart Failure
... implanted cardiac devices who are
experiencing
congestive heart failure.
The findings from the SEISMIC(1) ... standard medical
therapy and who are experiencing
congestive heart failure. On admission to
the trial, ... autologous stem-cell therapy in
the treatment of
congestive heart failure delivered via a ...
Final Data From the SEISMIC Trial Suggest Safety, Efficacy of Autologous Stem- Cell Therapy for Treating Congestive Heart Failure
... implanted cardiac devices who are
experiencing
congestive heart failure.
The findings from the SEISMIC(1) ... standard medical
therapy and who are experiencing
congestive heart failure. On admission to
the trial, ... autologous stem-cell therapy in
the treatment of
congestive heart failure delivered via a ...
Twelve DOXIL(R) Clinical Studies to be Presented at American Society of Hematology Annual Meeting
... toxicity. Myocardial damage may lead to
congestive heart failure and may occur as the total ... function should be carefully monitored --
congestive heart failure or cardiomyopathy may occur after ... lymphoma. Acute development or exacerbation of
congestive heart
failure, and/or new onset of decreased left ...
Palatin Technologies, Inc. Reports Initiation of Human Trials for the Treatment of Congestive Heart Failure
... long
term administration in patients with chronic
congestive heart failure. The Phase 1 trial of PL-3994 is a ... tool for physicians to advance the treatment of
congestive heart
failure. CHF is the single most common ... the subcutaneous route of administration. About
congestive Heart Failure (CHF) Currently in the U.S., CHF ...
Study Shows VAPRISOL(R) is Effective in Increasing Serum Sodium Levels and Well-Tolerated in Patients With Euvolemic or Hypervolemic Hyponatremia
... "Hyponatremia is common in patients with
congestive heart failure and
in patients with the syndrome ... VAPRISOL is not indicated for the treatment of
congestive heart
failure. It should only be used for the ... VAPRISOL is not indicated for the
treatment of
congestive heart failure. It should only be used for ...
World's First Cardiac Adult Stem Cell Patient Receives Infusion
... become the world's first recipient of adult cardiac stem cells to treat
congestive heart failure. Jones' infusion on July 17 marks the world's first ... coronary artery bypass surgery on Jones on March 23. Jones suffered from
congestive heart failure due to multiple blocked arteries that had resulted in ...
Responses After Completion of Therapy Increase Pixantrone Complete Remission (CR)/Unconfirmed Complete Remission (CRu) Rate to 24% and Overall Response Rate (ORR) to 40% Compared to 7% and 14% for Comparator Agents in Phase III EXTEND Trial in 3rd Line Th
... vs. 4.5%). Events considered cardiac disorders included cardiac arrest,
congestive heart failure, myocardial infarction, cyanosis, pericardial effusion, and ... (initial) treatment, they cause cumulative heart damage that may result in
congestive heart failure many years later. As a result, there is a lifetime limit of ...
Large, Long-Term Study Shows Avandia Has No Increased Overall Cardiovascular Risk Compared to Other Commonly Used Diabetes Medicines
... hospitalization or cardiovascular death (which includes heart attack,
congestive heart failure, and stroke) was not statistically different between the two ... diabetes that can lead to amputations, kidney failure and eye damage.
congestive heart failure is a known effect of Avandia and other drugs in the ...
FDA Submission of B-R-A-H-M-S MR-proANP Kryptor
... prospective, multi-marker trial called BACH (Biomarkers in
Acute
congestive Heart Failure). Enrolling 1641 patients presenting with
shortness of ... study demonstrated
MR-proANP to be a highly useful marker for diagnosing
congestive heart
failure. Furthermore it provides additional information especially ...
Two DOXIL(R) Studies to be Presented at American Society of Clinical Oncology (ASCO) Annual Meeting
... of DOXIL may lead to cardiac toxicity. Myocardial damage may lead to
congestive heart failure and may occur as the total cumulative dose of ... -- Cardiac function should be carefully monitored --
congestive heart failure or cardiomyopathy may occur after discontinuation ...
ATHENA Clinical Results with Dronedarone (Multaq(R)) Highlighted at the World Cardiology Congress
... an increased risk of stroke and
cardiovascular complications, including
congestive heart failure.
About Atrial Fibrillation / Flutter
Atrial fibrillation ... atrial fibrillation can lead to serious complications, such as
stroke and
congestive heart failure.
AF is a condition in which the upper chambers of the ...
Texas Heart(R) Institute at St. Luke's Episcopal Hospital Initiates First Clinical Trial in the World to Treat a Heart Attack Patient with a Special Stem Cell Type
... with a special type of stem cell to promote better healing and to
prevent
congestive heart failure, which many patients develop following a
heart attack.
Almost six million Americans have
congestive heart failure, a
progressive form of cardiovascular disease that inhibits ...
New Data Showed ACTOS(R) (pioglitazone HCl) Prevented Progression of Atherosclerotic Plaque Volume in Patients With Type 2 Diabetes
... data was collected by looking at macrovascular
events and episodes of
congestive heart failure (CHF). The number of
episodes of a common cardiovascular ... heart failure should
not start taking ACTOS. ACTOS can cause or worsen
congestive heart failure.
Talk to your doctor immediately if you experience rapid ...
Landmark ONTARGET(TM) Trial Demonstrates Micardis(R) is Equally Effective as Ramipril, with Fewer Discontinuations, in a Broad High-Risk Cardiovascular Population
... death, myocardial infarction,
stroke and hospitalization for
congestive heart failure (CHF) in patients
at risk. The study also compared the ... non-fatal myocardial infarction, non-fatal stroke and
hospitalization for
congestive heart failure. In addition, a broad variety
of secondary and tertiary ...
Study Shows Vasopressin Receptor Antagonist VAPRISOL(R) (Conivaptan Hydrochloride Injection) Significantly Increased Serum Sodium Concentration in Patients with Euvolemic & Hypervolemic Hyponatremia
... in hospitalized
patients. VAPRISOL is not indicated for the treatment of
congestive heart
failure. It should only be used for the treatment of hyponatremia ... in hospitalized patients. VAPRISOL is not indicated for the
treatment of
congestive heart failure. It should only be used for the
treatment of hyponatremia in ...
Leading Experts Endorse Bioheart's Muscle Stem Cell MyoCell Therapy
... Dr. Nabil Dib, Director, Cardiovascular Research, Mercy Gilbert & Chandler Medical Centers, added that "Myoblast transplantation to patients with
congestive heart failure and specifically to scar tissue (not living tissue) has shown that the cells survive, engraft and form new muscle and they do excrete ...
SIMPONI(TM) (golimumab) Receives Positive Opinion From CHMP for Once-Monthly Subcutaneous Treatment of Rheumatoid Arthritis, Psoriatic Arthritis and Ankylosing Spondylitis
... using any TNF-blocking therapy in COPD patients, as well as in patients with an increased risk for malignancy due to heavy smoking.
Worsening
congestive heart failure (CHF) and increased mortality due to CHF have been reported with another TNF blocker. SIMPONI has not been studied in patients with ....
West Wireless Health Institute Teams with Corventis for its First Multicenter, Randomized Clinical Trial
... detection, prevention and treatment of cardiovascular conditions.
(Logo: http://www.newscom.com/cgi-bin/prnh/20090624/DC137665LOGO )
congestive heart failure is the leading reason for hospital admission in the United States, and recently it was shown that 26.9% of patients in the Medicare ...
VivoMetrics(R) Introduces Next Generation LifeShirt Prototype, a Smart Garment That Delivers Real-time Vital Signs Remotely to Healthcare Providers
... using LifeShirt at nearly 300 leading research and academic institutions across a wide range of disease states, including sleep disordered breathing,
congestive heart failure, chronic obstructive pulmonary disease and cystic fibrosis. For more information, visit www.lifeshirt.com .
Forward-looking ...
Meta-Analysis of Clinical Data Showed No Increased Risk of Cardiovascular Events Associated With Exenatide Use: Data Presented at ADA 2009
... 0.53-1.21). CV events included stroke, myocardial ischemia, myocardial infarction, cardiac mortality, arrhythmia, revascularization procedures and
congestive heart failure.
About Diabetes
Diabetes affects more than 23 million people in the U.S. and an estimated 246 million adults worldwide.(i,ii) ...
Pixantrone in Combination with Chemotherapy Regimens Produces Overall Response Rates of 58-74% with Complete Remission Rates of 37-57% in Relapsed/Refractory Aggressive or Indolent NHL
... cancer. Although they are sufficiently effective to be used as first-line (initial) treatment, they cause cumulative heart damage that may result in
congestive heart failure many years later. As a result, there is a lifetime limit of anthracycline doses and most patients who previously have been treated with ...
Video: Data on More Than 15 Novartis Oncology Compounds at ASCO Highlight Progress Toward Targeted Therapies for Diverse Tumor Types
... pain (11%; 4%), nausea (6%; 4%), diarrhea (3%; 7%), and musculoskeletal pain (6%; 1%) were reported among patients receiving Gleevec.
Severe
congestive heart failure and left ventricular dysfunction have occasionally been reported. Most of the patients with reported cardiac events have had other ...
Celladon Corporation Announces Presentation of First-in-Human Gene Transfer to Treat Heart Failure at the 12th Annual Meeting of the American Society of Gene Therapy
... to enhance vector uptake in humans with numerous applications."
While conventional drug therapies have improved survival of patients with
congestive heart failure, the disease progresses relentlessly, resulting in more than 300,000 deaths each year, 6.5 million annual hospital days and an ...
Pixantrone Phase 3 Data to be Presented at the 2009 American Society of Clinical Oncology (ASCO) Annual Meeting
... cancer. Although they are sufficiently effective to be used as first-line (initial) treatment, they cause cumulative heart damage that may result in
congestive heart failure many years later. As a result, there is a lifetime limit of anthracycline doses and most patients who previously have been treated with ...
Metabolic Solutions Development Company Announces Preliminary Results from Phase IIa Clinical Trial
... increase in body weight.
Complications from the leading type 2 diabetic therapies include weight gain and edema as well as the potential for
congestive heart failure and bone loss.
"Our drug development program focuses on a different molecular target," said Colca. "We believe that selective ...
Video: Partnership Unites UCB with Consumer Product Innovator OXO(R)
... for the development of lymphoma. The potential role of TNF blocker therapy in the development of malignancies is not known.
Cases of worsening
congestive heart failure (CHF) and new onset CHF have been reported with TNF blockers. CIMZIA has not been formally studied in patients with CHF. Exercise ...
New Data Shows AZOR(R) (amlodipine and olmesartan medoxomil) Significantly Improves 24-Hour Ambulatory Blood Pressure
... duration, or severity of angina or acute myocardial infarction on starting calcium channel blocker therapy or at the time of dosage increase.
congestive Heart Failure
In general, calcium channel blockers should be used with caution in patients with heart failure.
Impaired Renal Function
In ...
Hyperion Therapeutics Receives Orphan Drug Designation for HPN-100 for the Treatment of Urea Cycle Disorders
... been reported to increase blood ammonia levels, and probenecid may affect the kidneys' excretion. Use with great care, if at all, in patients with
congestive heart failure or severe renal insufficiency, and in clinical states where there is sodium retention with edema. Use caution when administering to ...