comparative

Digital vs. Analog Mammography

...ut the thinnest breasts. Another analysis of the comparative performance of 18 digital mammography systems and 38 screen-film mammography systems showed that digital systems generally improve image quality for equal or lower breast doses, and provide tighter control on exposures and image quality. To determin...

PSA TestingHow Much is Too Much?

...the test in a result window. The company says that comparative studies have demonstrated that relative sensitivity of InstaTest PSA is 100 percent, and its relative specificity is 98.5 percent. Beckman Coulter, Inc., Fullerton, Calif., produces the Hybritech PSA Test and, as a confirmatory follow-up, the Hybrite...

Velcade (bortezomib) for Injection Based Induction Therapy Delivered High Post-Transplant Complete Remission Rate, a Critical Marker for Increased Overall Survival

... today reported that new data werepresented on the comparative Phase III clinical trial evaluating aVELCADE based...amycin and dexamethasone (VAD), whichserved as the comparative therapy in the trial. The data showedthat the VELCADE based therapy, compared to VAD, nearly doubled...

AMIA Announces 2008 Summit on Translational Bioinformatics

...ains. Thiseffort, which complements initiatives in comparative medicinewithin the scientific community, will provide a platform to shareinnovative research processes that are transforming health care andwill strengthen the clinical research enterprise. "AMIA looks forward to sponsoring its inaugural research me...

Modigene Announces Successful Completion of Pharmacokinetic & Pharmacodynamic Pre-Clinical Experiments for Proprietary Long-Acting Human Growth Hormone, Long-acting Interferon Beta and Long-acting Erythropoietin

...ustry standard animal models and methods aswell as comparative studies to the commercially available versions.Hum...in hasdemonstrated, in a pre-clinical animal model comparative study,increased durability and biological effect over Amgen Inc.'sAranesp(R), a long-acting erythrop...

Prexige Study Shows Significantly Less Impact on Blood Pressure Than Ibuprofen in Osteoarthritis Patients with Controlled Hypertension

...rthritis, rheumatoid arthritis, andhypertension: a comparative study. Ann Rheum Dis. 2004Apr;63(4):395-401. 6. Johnson AG, et al. Do nonsteroidalanti-inflammatory drugs affect blood pressure? A meta-analysis. AnnIntern Med 1994;121:289-300. 7. Aw TJ, et al. Meta-analysis ofcyclooxygenase-2 inhibitors and their e...

Sunesis Pharmaceuticals Reports Positive Data From Studies of Two Anti-Cancer Agents, SNS-595 and SNS-032, at the 12th Congress of the European Hematology Association

...ested in the clinic. Data presented on SNS-032from comparative studies show this promising product candidate ishitting its molecular targets, including Mcl-1, in peripheralmononuclear cells taken from patients undergoing treatment in adose-dependent fashion," said Dr. Adelman. "Our observationsrelating to SNS-03...

Cipralex demonstrates superiority to duloxetine for acute treatment of depression in new study

... (acute treatment). The double-blind, fixed-dose, comparative study included 294patients with MDD from 35 centres in nine countries. Patients wererandomised to either Cipralex® (n=143) or duloxetine (n=151),at dosing regimens currently recommended in the package inserts inparticipating countries (Cipralex&r...

Newly Published Data Demonstrates Superiority of Cipralex Over Duloxetine for Acute Treatment of Depression

...ks(acute treatment). The double-blind, fixed-dose, comparative studyincluded 294 patients with MDD from 35 centres in nine countries.Patients were randomised to either Cipralex(R) (n=143) orduloxetine (n=151), at dosing regimens recommended in the packageinserts in participating countries (Cipralex(R) 20mg, dulo...

Baraclude (Entecavir) Treatment Demonstrated Greater Viral Load Reduction Compared to Adefovir at 48 Weeks in Study of Antiviral-Naive Chronic Hepatitis B E-Antigen Positive Patients

...Study Study ETV-079 was a randomized, open-label, comparative viralkinetics study of antiviral-naive chronic HBeAg-positive patientsevaluating antiviral activity as measured by mean reduction inviral load, or levels of hepatitis B virus (HBV DNA) in the blood.HBeAg or e-antigen, is a viral protein associated wi...

AGI Dermatics Presents Comparative Data That Indicates OCTN-1 Skin Cells Have the Ability to Recognize, Transport and Utilize L-ergothioneine (EGT) As A Protector Against Oxidative Damage

...PRNewswire/ -- AGI Dermaticsrecently announced new comparative clinical data that indicatesthat OCTN-1 skin cells have the ability to recognize, transport andutilize L-ergothioneine (EGT) as a protector against oxidativedamage, and importantly, that (EGT) acts as a more powerful andefficient antioxidant than ide...

Bema Fentanyl Demonstrates Substantial Transmucosal Delivery In Absolute Bioavailability Study

...Although the studyannounced today was not a direct comparative study, our absoluteand buccal bioavailability results are greater than thosepreviously reported with Actiq(R) (47% and 22%), and similar tothose previously reported with Fentora(TM) (65% and 48%) inseparate studies. Given the linear increase in plasm...

Genzyme and Bayer HealthCare Announce Detailed Interim Two-Year Alemtuzumab in Multiple Sclerosis Data Presented at AAN

Interim analysis of Phase 2 comparative study showed significantresults in favor of alemtuzumab versus Rebif CAMBRIDGE, Mass. and WAYNE, N.J., May 02, 2007/PRNewswire-FirstCall/ -- Genzyme Corporation and Bayer HealthCarePharmaceutical today announced detailed interim results from theCAMMS...

First Controlled Large-Scale Intervention Angiotensin Receptor Blocker (ARB) Trial in a Japanese Population, JIKEI HEART Study Demonstrates Significant Reduction in Blood Pressure and Protection of Organs with Valsartan

...RT Study The JIKEI HEART Study was a multi-center comparative study witha prospective randomized open-label blinded endpoint (PROBE) designconducted by physicians. The study involved 3,081 Japanese patientsaged 20 to 79 with hypertension, ischemic heart disease orcongestive heart failure. The primary endpoint w...

Antares Pharma Announces Positive Results from Application Site Study for Anturol

...t skin sitelocations. The study was an open-label, comparative three-way crossover,application site pharmacokinetic study. The trial enrolled 25healthy subjects (80% women), aged 18 to 42, who received one doseof ANTUROL(R) applied topically on three skin sites: abdomen,thighs or shoulders alternatively with 10 ...

EntreMed Presents Mechanism Data for Its Three Lead Oncology Compounds

...atory diseases,today announced the presentation of comparative mechanism of actiondata for its three lead clinical stage compounds Panzem(R), MKC-1and ENMD-1198. These data were presented by Dr. Theresa M.LaVallee, EntreMed's Senior Director, Cell Biology in an oralpodium session during the Apoptosis in Drug Dis...

First Study To Show Positive Benefit On Atherosclerosis For People With Early Signs Of Diseased Arteries

...dicatedfor statin therapy to permit inclusion of a comparative placeboarm. Currently, CRESTOR is indicated for the treatment of lipiddisorders. The results from the METEOR study, supported by datafrom the ASTEROID study and including the ORION trial, formed thebasis of the atherosclerosis regulatory submissions...

Hospitalization Rates for Coronary Artery Disease Decline in the U.S.

...nhancing healthcare information, Solucientprovides comparative measurements of cost, quality and marketperformance. Solucient's expertise and proven solutions enableproviders and pharmaceutical companies to drive business growth,manage costs and deliver high quality care. For more information,visit <a target...

Tapestry Pharmaceuticals to Present Data on TPI 287 at the 2007 AACR Annual Meeting

...nimalxenograft models when tested against standard comparative agents.The in vitro activity was seen across multiple cell lines includingcell lines known to be sensitive to taxanes and cell lines known tobe resistant to taxanes. Taxane sensitive cell lines in which TPI287 has shown activity include cell lines de...