chain

Rapid Flu Tests May Prove Especially Helpful This Season

...lture, serology, rapid antigen testing, polymerase chain reaction (PCR) and immunofluorescence testing. All are time-consuming, however, in a year when time is especially important. Fortunately, three medical firms produce quick-results kits that have been CLIA-waived by the CDC for point-of-care use. Wit...

The Past, Present and Future of HLA Typing

...ide probes to HLA loci amplified by the polymerase chain reaction (PCR), or by using PCR to amplify the HLA DNA directly through differential primer extension. One of the most commonly employed strategies in HLA DNA typing is to first amplify a given HLA locus, then hybridize it with a labeled, sequence sp...

DOR BioPharma Announces Issuance of European Patent for Its Oral Multivalent Botulinum Toxin Vaccine BT-VACC

...mposed of acomponent of what is known as the heavy chain of each of the A, B,and E serotypes of botulinum toxin. The heavy chain component lacksthe region of the toxin that is responsible for blockingneurotransmitter functions. T...

DOR BioPharma Announces Publication Describing Results of Its Multivalent Botulinum Toxin Vaccine BT-VACC

...mposed of a component of what is known asthe heavy chain of each of the A, B, and E serotypes. Thesecomponents lack the region of the toxin that are responsible forblocking neurotransmitter functions. The subunits can bind avidlyto receptors on the surface of mucosal cells and traverse lung andgastrointest...

Researchers Discover Gene For Rare Skin Disorder

...other proteinswithin the cell to begin the complex chain of events leading to thedevelopment and differentiation of organ systems in early life. This discovery may lead to greater understanding of the functionof Wnt proteins in humans, said Dr. Van den Veyver. By identifying the genetic defect which caus...

Second Successful Quigley QR-443 Study Suggests Method of Action Relevant to Broad Range of Chronic Inflammatory Diseases - Human Study to Follow -

...salers anddistributors, as well as independent and chain food, drug and massmerchandise stores and pharmacies. The Quigley Corporation has four(4) wholly owned subsidiaries. Darius International markets healthand wellness products through its wholly owned subsidiary,InnerLight Inc. Quigley Manufacturing In...

Geron's Telomerase Inhibitor Cancer Drug Demonstrates Good Pharmacokinetics and Tolerability in Phase I/II Trial

... in most normal adult tissues. GRN163L is a short chain oligonucleotide that is unique in itsresistance to nuclease digestion in blood and tissues and its veryhigh affinity and specificity for telomerase. The molecule hassuperior cellular and tissue penetration properties due to itsproprietary manufacturi...

CEL-SCI'S CEL-1000 Shown to Significantly Enhance Immune Response Against Avian Flu Antigen in Animals

...nfectious agents. CEL-1000, derived from the beta chain of human MHC-II, is amodified version of a human immune-based protein known to bind toboth human and mouse immune cells and appears to act by enhancingthe host's protective immune response. More information on CEL-1000is available at <a target="_...

Baraclude (Entecavir) Treatment Demonstrated Greater Viral Load Reduction Compared to Adefovir at 48 Weeks in Study of Antiviral-Naive Chronic Hepatitis B E-Antigen Positive Patients

...DNA measured by a common assay --polymerase chain reaction, or PCR) Week 24 * BARACLUDE-treated patients achieved a meanchange in viral load of -6.97 log(10) copies/mL, andadefovir-treated patients achieved a mean change of -4.84 log(10) copies/mL (95percent Confidence Interval...

Genelabs Technologies Announces Presentation of Data on Non-Nucleoside HCV Polymerase Inhibitor at 20th International Conference on Antiviral Research Meeting

... of HCVantiviral compounds, including a nucleoside chain terminator, aprotease inhibitor and interferon alp... other likely therapeuticdrugs, such as nucleoside chain terminators or protease inhibitors,may be feasible." About Genelabs Technologies Genelabs Technolo...

CEL-SCI's Cel-1000 Shown to Significantly Enhance Immune Response Against Hepatitis B Antigen in Animals

...nfectious agents. CEL-1000, derived from the beta chain of human MHC-II, is amodified version of a human immune-based protein known to bind toboth human and mouse immune cells and appears to act by enhancingthe host's protective immune response. More information on CEL-1000is available at <a target="_...

Gentium's Defibrotide Highlighted in Two Poster Presentations at American Association for Cancer Research Annual Meeting

...pression was evaluated through real timepolymerase chain reaction (RT-PCR) of cDNA prepared from the twolines of MM cells treated with Defibrotide or saline. Heparanaseactivity was measured in MM cells treated with Defibrotide (at 50,100 and 150 (mu)g/ml) or saline for 24 hours by using aheparan-degrading ...

Baraclude (entecavir) Therapy Resulted in Undetectable Levels of Hepatitis B Virus in Cohort of Patients Who Re-Started Treatment

... copies/mL, measured by acommon assay - polymerase chain reaction or PCR) and 83 percentachieved liver enzyme normalization (ALT less than or equal to1xULN) after 48 weeks of therapy. "This study showed that when treated again with BARACLUDE for 48weeks, patients achieved responses similar to those seen...