Chain in Medical Technology

Tourtellotte Solutions Blazes Trail with New Release of Clinical Trial Supply Chain Simulator

... leader in off-the-shelf and custom supply chain software for the biopharmaceutical, retail, and ... 3.0 release also expands modeling up the supply chain to include pharmaceutical ingredients and other ... tcVisualize(TM), a groundbreaking clinical supply chain modeling and forecasting application for the ...

Intellect Neurosciences, Inc. and Medical Research Council Technology (U.K.) Reach Important Milestone in Generating an Alzheimer's Therapeutic Antibody

... invented by Dr. Daniel Chain, the Company's Chairman and CEO. Dr. chain commented: "IN-N01 is designed to specifically block the neurotoxicity of ... patients, while minimizing the potential for adverse effects." Dr. chain added: "IN-N01 is similar to Bapineuzumab being developed independently by ...

Velos to Develop Key System Interface for Clinical Research

... in its current automated form is still an incomplete system supply chain as a result of work redundancies at the site that are, in effect, ... result from improved clinical trial timeliness that an integrated supply chain model creates. These gains in turn translate to better treatment options ...

Twelve DOXIL(R) Clinical Studies to be Presented at American Society of Hematology Annual Meeting

... (Poster Board #:930-II) -- Early Normalization of Serum Free Light chain Is Associated with Prolonged Time to Progression Following Bortezomib ... p.m., Hall B3 and B4 (Poster Board #: 925-II) -- Serum Free Light chain Analysis Improves Monitoring of Multiple Myeloma Patients Receiving ...

Microarray Sequence Capture Speeds Large-Scale Resequencing of Targeted Genomic Regions

... genomic regions for resequencing has primarily relied on PCR (polymerase chain reaction) to enrich for specific DNA fragments. However, PCR is limited in ... and highly accurate reads. "This new technology will replace polymerase chain reaction (PCR) for many purposes," said Gibbs. "If the aim is to sequence ...

Intellect Neurosciences, Inc. to Present Data on Alzheimer's Vaccine at 13th International Congress of Immunology Conference

... sponsored by major pharmaceutical companies," commented Professor Benjamin chain at the Department of Immunology and Molecular Pathology, Windeyer Institute of Medical Sciences, University College London. Professor chain added: "The major challenges are the need to: (i) mount a robust immune ...

University of Michigan Study Shows SEQUENOM's MassARRAY Technology Identifies HPV Infections Missed by Standard Hybridization Test

... by SEQUENOM and known as the AttoSense(TM) HPV assay). Utilizing SEQUENOM's proprietary MassARRAY((R)) system that couples standard polymerase chain reaction (PCR) techniques with mass spectrometry (PCR-MS), study samples were simultaneously screened, genotyped and quantified for each of 13 HPV ...

Alfacell Provides Shareholder Update

... Onconase to three mesothelioma cell lines at a dose which is achievable in humans, and then using molecular biology techniques including polymerase chain reaction, measured the levels of the MDR and nfkB genes after treatment with the drug. Striking decreases in all of these genes in the mesothelioma ...

Great Basin Scientific, Inc. Raises $3.6 Million in Bridge Funding to Prepare for Launch of First Product

... of which certain types can lead to cervical cancer. Great Basin Scientific's technology has several advantages over the traditional Polymerase chain Reaction (PCR) method that requires the skills of highly-trained technicians and often times multiple rooms to avoid cross contamination of tests. ...

MacroGenics and Lilly Achieve Targeted Patient Enrollment in PROTEGE, a Global Phase 2/3 Clinical Trial of Teplizumab in Type 1 Diabetes

... that mediate the destruction of the insulin-producing beta cells of the islets of the pancreas. Teplizumab binds to an epitope of the CD3-epsilon chain expressed on mature T cells and by doing so, may modulate the immunologic response that is a key component of the disease. If teplizumab is effective ...

Cepheid Receives Grant to Develop Ten-Color Real-Time PCR Detection Technology for Use in the GeneXpert(R) System

... with minimal risk of contamination. The GeneXpert System is the only system to combine on-board sample preparation with real-time PCR (polymerase chain reaction) amplification and detection functions for fully integrated and automated nucleic acid analysis. The system is designed to purify, ...

Dow AgroSciences, World Wide Wheat Agree to Collaborate on Wheat

... said Sheldon Richardson, chairman and CEO of W3. "With Dow AgroSciences as our partner, we can leverage customer relationships within the food chain and their marketing and commercialization expertise. Our four decades of plant breeding experience brings a wide diversity of germplasm offering of ...

Quest Diagnostics Introduces First Commercial Laboratory Test for Identifying the H1N1 Swine Flu Virus

... today announced that its Focus Diagnostics infectious disease reference laboratory has introduced a laboratory-developed real-time polymerase chain reaction (PCR) test to aid in identifying Influenza A H1N1 Swine-origin (H1N1) flu virus ("S-OIV" or "novel H1N1"), also known as the Swine Flu. The ...

HIV/AIDS Research Network Recommends Use of Abbott RealTime Viral Load Test for NIH-Sponsored Clinical Trials

... m 2000 Instrument System The Abbott RealTi m e HIV-1 test runs on the Abbott m 2000, an automated system that uses real-time polymerase chain reaction (PCR) to amplify, detect and measure minute levels of virus in blood samples as well as extremely high levels of these infectious agents. ...

Jubilant Enters Research Collaboration With AstraZeneca

... services (CRAMS) and drug discovery and development services companies out of India. The company has a presence across the pharmaceutical value chain for products and services such as proprietary products ,exclusive synthesis, active pharmaceutical ingredients, contract manufacturing of sterile ...

Perceptive Informatics Survey Results Reveal Top Barriers to Implementing Adaptive Trial Designs

... included understanding and implementing complex statistical methodologies as well as difficulties in medication supplies estimation and supply chain management. "Formal FDA guidance on adaptive trials implementation is expected later this year and should help to alleviate regulatory ...

The Villa Group Informs on Mexico Travel Plans in Wake of Swine Flu Outbreak

... it becomes available at: www.usembassy-mexico.gov . About The Villa Group Founded in 1984, The Villa Group has been awarded the 2008 TOP chain in Mexico from Expedia. The company's portfolio includes beachfront resorts and timeshare resorts located in Puerto Vallarta, Nuevo Vallarta/Riviera ...

Cepheid Announces European Release of First On-Demand Molecular Test for Simultaneous Detection of Mycobacterium tuberculosis (TB) and Resistance to Rifampicin

... with minimal risk of contamination. The GeneXpert System is the only system to combine on-board sample preparation with real-time PCR (polymerase chain reaction) amplification and detection functions for fully integrated and automated nucleic acid analysis. The system is designed to purify, ...

Genetic Source of Rare Childhood Cancer Found; Gene is Implicated in Other Cancers

... Pleuropulmonary Blastoma Registry at Children's Hospitals and Clinics of Minnesota and other collaborating institutions adds the final link to the chain connecting the gene DICER1 to cancer development -- something that had been suspected but until now not definitively demonstrated. The results ...

Trubion Pharmaceuticals, Inc. Announces Upcoming Presentation at the 2009 American Association of Cancer Research Annual Meeting

... presented at the AACR Annual Meeting on April 22, 2009. Trubion's SCORPION (TM) Therapeutics Like Trubion's SMIP(TM) therapeutics -- single chain polypeptides comprising one binding domain, one hinge domain and one effector domain -- SCORPION therapeutics are also novel, single-chain ...

Intellect Neurosciences, Inc. Announces Independent Studies on Copper Binding Properties of its Lead Candidate OXIGON(TM)

... Dr. Daniel Chain, Intellect's Chairman and CEO commented: "We were very interested to learn that OXIGON(TM) has metal binding properties." Dr. chain added: "These data fit perfectly with those previously reported by Professor Blas Frangione and his colleagues from New York University more than ...

White Paper Explains Aspects of Testing From Purified Bulk Drug Substance to Sterile Liquid Final Drug Product

... USA, the company's expertise and flexible processes enhance product safety and security, accelerate time to market, and minimize supply chain disruption. For more information, visit www.microtestlabs.com or call 1-413-786-1680 or toll-free 1-800-631-1680. Available Topic Expert(s): ...

The Quigley Corporation Licenses Naturally Derived Compound For Scar Improvement; License Requires Payments Totaling $1.1 Million To The Quigley Corporation Over A Five Year Period For Exclusive Ownership

... proven to cut the common cold nearly in half. COLD-EEZE customers include leading national wholesalers and distributors, as well as independent and chain food, drug and mass merchandise stores and pharmacies. The Quigley Corporation has wholly owned subsidiaries; Quigley Manufacturing Inc. consists of ...

Data from Phase 2 Study of Peramivir in Patients Hospitalized with Influenza Presented at the XI International Symposium on Respiratory Viral Infections

... or severity of illness requiring supportive care. Of the 137 patients randomized, 122 age 19 to 101 years had influenza confirmed by polymerase chain reaction (PCR) testing and were included in the intent-to-treat infected (ITTI) patient population; 41 patients received oseltamivir 75 mg orally ...

Quark Pharmaceuticals Announces Dosing of the First Patient in Phase I/II Clinical Trial for Systemically Delivered siRNA Drug Candidate for Delayed Graft Function

... results most often from ischemia-reperfusion injury that occurs when the blood flow is re-established to the transplanted kidney initiating a chain of events that can lead to severe renal damage upon transplantation. Post-kidney transplant DGF is associated with longer hospital stays and higher ...

WaferGen and University of Texas Southwestern Medical Center Establish Biomarker Research Collaboration for SmartChip(TM) Real-Time PCR System

... gene expression and genotyping markets. SmartChip is being developed as the first whole genome, high throughput gene expression real-time polymerase chain reaction (PCR) platform. This innovative system, combined with next-generation chemistry and optimized assays being developed by WaferGen, promises ...

Diagenic Announces Launch of First Breast Cancer Gene-Expression Blood Test

... The DiaGenic BCtect(TM) breast cancer test will be marketed in India through Religare SRL (formerly known as SRL Ranbaxy), the largest laboratory chain in South East Asia. Sanjeev K. Chaudhry, M.D, CEO of SRL predicts high demand for the DiaGenic test. "We believe that BCtect(TM) will provide the ...

Quigley Anti-Viral Compound QR448(a) Successfully Prevents Transmission of Infectious Bronchitis in Chickens

... proven to cut the common cold nearly in half. COLD-EEZE customers include leading national wholesalers and distributors, as well as independent and chain food, drug and mass merchandise stores and pharmacies. The Quigley Corporation has wholly owned subsidiaries; Quigley Manufacturing Inc. consists of ...

Genomic Health Announces Data Supporting Use of Oncotype DX(R) to Accurately Assess HER2 Gene Expression in Breast Cancer Patients

... patient-specific information and insight into each patient's individual tumor biology." Oncotype DX uses reverse transcription-polymerase chain reaction (RT-PCR) technology to quantify gene expression of 21 genes, one of which is HER2. The two studies found high concordance for testing with ...

Diakron Licenses Anticoagulant Drug Candidate from Merck & Co., Inc.

... has research and manufacturing facilities aimed at global markets, thus emerging as a world-class pharmaceutical company covering the entire value chain from "Discovery to Delivery." Contacts: Diakron: Robert A. Anderson Chief Marketing Officer randerson@diakron.com ...

Alzheimer's Foundation of America Survey: Americans With Memory Concerns Fall Short of Talking to Doctors

... Day, which will be held on November 18. Free confidential screenings will be available nationwide at various community sites, including the entire chain of 1,100 Kmart pharmacies, local Alzheimer's agencies, senior and community centers, assisted living facilities, adult day centers, and doctor's ...

CB1400, Patented by Canopus BioPharma, Enters Phase II Clinical Trials for the Prevention of Mucositis in Patients With Cancer of the Head and Neck

... of progress and improvement in assay methods and monitoring capabilities for physicians, patients and researchers, particularly for food chain protection applications. Canopus maintains staff in Australia, South Africa, Ireland, Panama and the USA. Additional information on the Company is ...

Trubion Announces Presentation of Positive TRU-016 Data at ASCO

... safety, efficacy, and convenience that it believes may offer improved patient experiences. Trubion's current product candidates are novel single- chain protein, or SMIP(TM), therapeutics, and are designed using its custom drug assembly technology. Trubion's product pipeline includes CD20-directed ...

Magellan Biosciences Companies to Feature Automated Products and New Tests for MRSA at the American Society for Microbiology Meeting, Booth 743

... easily processes two 96-well microplates and up to 12 different assays simultaneously and features the most user-friendly control system available, chain of custody, and instrument diagnostics. "MRSA is a growing concern in healthcare," said Magellan President and CEO, Robert J. Rosenthal, Ph.D. ...

ViroPharma Announces Completion of Enrollment in Phase 3 Study of Maribavir in Stem Cell Transplant Patients

... includes weekly testing at a central laboratory for the presence of CMV pp65 antigenemia and for the presence of CMV DNA in plasma using a polymerase chain reaction (PCR). If CMV infection is detected during the study drug administration period (or if CMV organ disease is diagnosed), study drug will be ...

Omega 3 Fatty Acids Bound to Phospholipids has Potential Benefit for Attention-Deficit Hyperactivity Disorder (ADHD)

... at a temperature lower than 60 degrees C. The omega 3 fatty acids, EPA and DHA can be extracted maintaining their position on the triglyceride chain using this patented process and keeping their natural proportions and composition. This patented innovation, called vectorization, uses a gentle, ...

Quigley Announces Successful Poultry Study of Chickens With Infectious Bronchitis; Plans to Approach the Poultry Industry for Potential Commercialization

... proven to cut the common cold nearly in half. COLD-EEZE customers include leading national wholesalers and distributors, as well as independent and chain food, drug and mass merchandise stores and pharmacies. The Quigley Corporation has wholly owned subsidiaries; Quigley Manufacturing Inc. consists of ...

BARACLUDE(R) (Entecavir) Treatment Resulted In Greater Viral Load Suppression Compared to Adefovir at 96 Weeks In Antiviral-Naive Adult Chronic Hepatitis B E-Antigen Positive Patients

... 50 percent (n=10/20) of adefovir-treated patients had undetectable viral load (HBV DNA less than 300 copies/mL, measured by the polymerase chain reaction or PCR assay). -- No BARACLUDE-treated patient (n=0/29) and 35 percent (n=7/20) of adefovir-treated patients had viral load greater ...

Trubion Announces Initiation of Phase 1 Study of SBI-087 for the Treatment of Rheumatoid Arthritis

... safety, efficacy, and convenience that it believes may offer improved patient experiences. Trubion's current product candidates are novel single- chain protein, or SMIP(TM), therapeutics, and are designed using its custom drug assembly technology. Trubion's product pipeline includes CD20-directed ...

Treximet(TM) (Sumatriptan and Naproxen Sodium) Tablets Approved by FDA for Acute Treatment of Migraine

... was a vascular condition, induced by blood vessel dilation alone. Today, new insight suggests that migraine is much more complex, involving a chain of events that are both neurovascular and inflammatory. Treximet contains sumatriptan that mediates vasoconstriction, which correlates with the ...