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Vectibix(R) in Combination With Chemotherapy Significantly Improved Progression-Free Survival in First-Line Metastatic Colorectal Cancer

... indicate that KRAS plays an important role in cell growth regulation. In mCRC, EGFR transmits ... the nucleus, these signals instruct the cancer cell to reproduce and metastasize, leading to cancer ... sometimes, even adequately modeled by computer or cell culture systems or animal models. The length of ...

Juvenile Diabetes Research Foundation, The Genomics Institute of the Novartis Research Foundation Announce Innovative Diabetes Drug Discovery and Development Partnership

... The initial focus will be on pancreatic beta cell regeneration and survival, to restore beta cell function in diabetes. The program builds on ... at GNF that has resulted in the discovery of beta cell regeneration drug targets and candidates, and ...

Telik Announces Publication of Positive Phase 1 Results of a Multicenter Study of Ezatiostat Hydrochloride (TELINTRA(R), TLK199) Tablets In Patients With Myelodysplastic Syndrome

... MDS is a heterogeneous group of blood stem cell disorders of increasing incidence. MDS is characterized by ineffective blood cell production involving one or more of the red cell, white cell or platelet lineages and with MDS patients having ...

OPAXIO(TM) Combined with Alimta(R) Well Tolerated in Dose-Ranging Study of Patients with Advanced Non-Small Cell Lung Cancer

... SEATTLE, Aug. 3 /PRNewswire-FirstCall/ -- cell Therapeutics, Inc. (CTI) (Nasdaq and MTA: CTIC) ... that in patients with advanced non-small cell lung cancer (NSCLC), the combination of OPAXIO ... compared to standard therapies. About cell Therapeutics, Inc. Headquartered in Seattle, ...

Study Shows Cancer Vaccines Led to Long-Term Survival for Patients with Metastatic Melanoma and to Long Periods of Disease Control After Completion of Therapy

... from their peripheral blood and mixed with a cell culture of the patient's own melanoma cells that ... months, p=.016). Eight patients in the dendritic cell vaccine study experienced remarkable long-term, ... patient-specific biological treatments in its cell biology laboratory, and provides a wealth of ...

Cryo-Cell Announces C'elle(SM) Research and Development Collaboration with Cryopraxis Cryobiology Ltd.

... the largest and most established leaders in stem cell innovation today announced a research and ... global regenerative technology leader and stem cell research company. The partnership will allow ... a global leader in regenerative medicine and stem cell R&D, to explore the utilization and potential ...

Injection Reverses Heart-Attack Damage

... heart defects. In the July 24 issue of cell , they show that a growth factor called ... cells (cardiomyocytes) normally withdraw from the cell cycle - meaning they stop dividing and ... at Children's, were able to restart the cell cycle with NRG1, stimulating cardiomyocytes to ...

National Cancer Institute Research Identifies Unique Mechanism of Brostallicin's Anti-Tumor Effectiveness

... SEATTLE, July 21 /PRNewswire-FirstCall/ -- cell Therapeutics (CTI) (Nasdaq and MTA: CTIC) ... the NCI research indicates that the tumor cell DNA damaging effects of brostallicin are enhanced ... was active in a trabectedin-resistant cell line. "These preclinical data provide ...

Bionovo's Estrogen Receptor Beta Selective Drugs Have Unique Gene Expression and Cell Type Specificity

... that a study of the gene regulation in multiple cell lines by several of their estrogen receptor beta ... hormone therapy. The study also demonstrates the cell type selectivity of Menerba (MF101) and ... of Bionovo's ERb selective drugs, in different cell types. These compelling findings will serve as a ...

Oncolytics Biotech(R) Inc. Announces Publication of Research on Synergistic Activity of Reovirus and Chemotherapy in NSCLC

... reovirus and chemotherapy against human non-small cell lung cancer (NSCLC). The paper, entitled ... Reovirus and Chemotherapeutic Agents in Non-Small cell Lung Cancer Cells" appears online in the July 14, ... significant multiple drug resistance in certain cell lines," said Dr. Brad Thompson, President and CEO ...

Cystic Fibrosis - Liposomal Tobramycin Receives Second Orphan Drug Designation Within Weeks

... due to the impermeability of B. cepacia's cell envelope. In addition, B. cepacia - just like ... rescue mechanisms that pump tobramycin out of the cell are inhibited by the fusion process. The ... maximum release of tobramycin into the bacterial cell together with inhibition of the clearance ...

Keryx Biopharmaceuticals, Inc. Commences Phase 1 Study of KRX-0401 (Perifosine) in Recurrent Pediatric Solid Tumors at Memorial Sloan-Kettering Cancer Center

... which are pathways associated with programmed cell death, cell growth, cell differentiation ...

Bioniche Life Sciences Inc. and Endo Pharmaceuticals Sign Licensing Agreement for Urocidin(TM)

... is a patented formulation of Mycobacterial cell Wall-DNA Complex (MCC) developed by Bioniche for ... is a formulation of MCC, a sterile mycobacterial cell wall-DNA complex composition that has a dual mode ... to the development of Bioniche's mycobacterial cell wall technologies by means of a C$9.6 million ...

CEL-SCI to Present Data from Multikine Clinical Trials at National Institutes of Health (NIH), National Cancer Institute (NCI) Seminar Series

... (treatment naive) patients with Squamous cell Carcinoma of the Head and Neck. Early ... primary Head and Neck cancer (Oral Squamous cell Carcinoma) during the impending Multikine Pivotal ... to utilize to launch aseptic filling for stem cell produced therapies and other biological products. ...

Leading Experts Endorse Bioheart's Muscle Stem Cell MyoCell Therapy

... clinical trials (MARVEL) to advance muscle stem cell (myoblast) therapy for treating heart failure to ... of Medicine, discussed the difficulties of stem cell therapy in scar tissue. "Cells of the myoblast ... therapy is at this time point the only stem cell therapy that is making the claim to actually ...

Sangamo BioSciences Announces Achievement of Key Milestone in Cell Engineering Agreement With Genentech

... member of the Roche Group, for the generation of cell lines with novel characteristics for ... genes in a Chinese hamster ovary (CHO) cell line. The milestone achievement triggered a ... protein production to streamline the process of cell line production, increase the yield and improve ...

Alfacell Provides Shareholder Update

... genes, we added Onconase to three mesothelioma cell lines at a dose which is achievable in humans, ... in all of these genes in the mesothelioma cell lines were seen after treatment with Onconase ... to chemotherapy. Moreover, these data in cell lines are complemented by most recent animal ...

Families of Spinal Muscular Atrophy Announces Latest Developments on Three SMA Drug Discovery Programs

... neuron replacement program at California Stem cell and UCI. These three programs represent an ... Neuron Replacement Program: California Stem cell (CSC) is preparing for a final FDA pre-IND ... for the use of these cells in development of a cell replacement therapy for SMA Type I. Numerous ...

HEALTHPOINT-Sponsored Venous Leg Ulcer Clinical Trial Enrolls First Subject for Second Phase II Study

... of the trial protocol. "This is the largest cell therapy dose ranging trial ever undertaken in the ... promising results over a four-fold range of cell concentrations administered weekly. This ... both keratinocytes and fibroblasts, the two major cell types found in human skin. Using a unique ...

UPCI Joins ExCell Research Study Using Stem Cells for Leukemia and Lymphoma Patients

... Cancer Institute (UPCI) and the Gamida cell - Teva Joint Venture announced today that the ... clinical director of UPCI's Hematopoietic Stem cell Transplant Program. "Using umbilical cord blood ... 10th in funding from the NCI. About Gamida cell ...

Two-Year Data Show Patients Receiving SIMPONI(TM) (golimumab) Experienced Sustained Improvement in Signs and Symptoms of Psoriatic Arthritis and Ankylosing Spondylitis

... reported through week 104 included basal cell skin cancer (one patient), colon cancer (one patient) and small cell lung cancer (one patient) in patients receiving SIMPONI 50 mg, and basal cell skin cancer (three patients), prostate cancer ...

ThermoGenesis Announces National Institute of Health Grant

... FIRST-EVER NIH GRANT WILL BE USED TO DEVELOP cell DELIVERY TECHNOLOGIES FOR REGENERATIVE MEDICINE ... The study will be conducted at the Company's stem cell research laboratory and through a collaboration ... Officer of ThermoGenesis. "We will be using stem cell concentrates prepared by our AXP(TM) AutoXpress ...

DOR BioPharma Receives EMEA Agreement on the Design of its Confirmatory Phase 3 Clinical Trial of orBec(R) in GI GVHD

... orBec(R) conducted at 16 leading bone marrow/stem cell transplantation centers in the US and France. ... cancer patients after receiving hematopoietic cell transplantation. Unlike organ transplants where ... life-threatening complication of hematopoietic cell transplantation. DOR expects to begin a ...

Tolerx Presents Data at 69th Scientific Sessions of the American Diabetes Association

... of autoimmune type 1 diabetes, will preserve beta cell function as measured by c-peptide, a surrogate measure of beta cell function. The primary endpoint will be a measurement of C-peptide, a surrogate measure of beta cell function. For information about DEFEND, please ...

Afinitor(R) Phase II Data Show Positive Results for Patients With Multiple Types of Lymphoma, Leading to Phase III Trial

... the immune system, such as DLBCL, mantle cell lymphoma and follicular lymphoma(2). Up to 60% of ... Hodgkin's disease, follicular lymphoma, mantle cell lymphoma, DLBCL and small lymphocytic lymphoma; ... (53% ORR), follicular lymphoma (50% ORR), mantle cell lymphoma (32% ORR), DLBCL (30% ORR) and small ...

Three Surgeons in East Texas Are Successfully Integrating a Novel Stem Cell Procedure for Spine Surgeries

... Stem cell Technologies for Surgery TEXARKANA, Texas, ... /PRNewswire/ -- A new breakthrough in adult stem cell technology has three Texarkana neurosurgeons ... adoption to benefit all patients in need of cell therapy. "As a neurosurgeon, I pride myself ...

Paclitaxel Poliglumex (OPAXIO(TM)) Added to Cisplatin and Radiation Produces 45% Pathologic Complete Remissions in Patients With Esophageal Cancer

... ORLANDO, Fla., June 3 /PRNewswire-FirstCall/ -- cell Therapeutics, Inc. ("CTI") (Nasdaq and MTA: CTIC) ... to 2.0, OPAXIO increases tumor specific radiation cell kill by a factor of 7.2 to 8.4 -fold (Milas Luka ... locally advanced adenocarcinoma or squamous cell carcinoma of the esophagus or gastro-esophageal ...

Proteolix Presents Positive Clinical Data for Carfilzomib in Multiple Myeloma at the 2009 ASCO Annual Meeting

... Myeloma Program, Bone Marrow and Blood Stem cell Transplantation at St. Vincent's Comprehensive ... and dexamethasone during the "Lymphoma and Plasma cell Disorders" poster session. "In spite of ... prior treatment with all approved agents and stem cell transplant." Sustained Clinical Benefit in ...

Keryx Biopharmaceuticals Announces Positive Data from a Randomized, Multi-Center, Placebo-Controlled, Phase 2 Combination Study of KRX-0401 (Perifosine) in the Treatment of Advanced Metastatic Colon Cancer

... which are pathways associated with programmed cell death, cell growth, cell differentiation ...

Study Showed Lilly's GEMZAR(R) (gemcitabine HCl for injection) Improved Progression-Free Survival in Cervical Cancer Patients

... were hematologic, including anemia (low red blood cell count), neutropenia (low white blood cell count) and thrombocytopenia (low blood platelet ... (Stage IV or cancer that has spread) non-small cell lung cancer for whom surgery is not possible. ...

Keryx Biopharmaceuticals Reports Positive Data from a Randomized, Multi-Center, Placebo-Controlled, Phase 2 Combination Study of KRX-0401 (Perifosine) in the Treatment of Advanced Metastatic Colon Cancer

... which are pathways associated with programmed cell death, cell growth, cell differentiation ...

Proteolix Presents Phase 1b/2 Clinical Data for Carfilzomib in Advanced Solid Tumor Patients at the 2009 ASCO Annual Meeting

... according to disease type, including non-small cell lung cancer, small cell lung cancer, ovarian cancer and renal cancer. ... responses observed in renal cancer and small cell lung cancer patients. A total of 55 patients ...

Video: Phase III Study Data With Vandetanib (Zactima(TM)) in Patients With Advanced Non-Small Cell Lung Cancer (NSCLC) Presented at American Society of Clinical Oncology

... the Phase III ZODIAC study in advanced non-small cell lung cancer patients, with the investigational ... rash, diarrhea and neutropenia (low white blood cell count) (ZODIAC). Incidence of protocol-defined ... prostate cancer combined(4). Non-small cell lung cancer accounts for around 85% of all lung ...

Semafore's SF1126, a Vascular Targeted Pan-PI3K/mTOR Inhibitor, Is Well Tolerated and Demonstrates Activity in Phase I Solid Tumor Patients

... is designed to inhibit both angiogenesis and cell proliferation by targeting and binding to ... transduction and are important in controlling cell growth/angiogenesis, differentiation, ... AKT and mTOR is also known to promote tumor cell survival, proliferation, and growth. ...

Bayer Announces New Data on Novel Anti-cancer Compound BAY 73-4506

... data from the Phase II, open-label study in renal cell carcinoma (RCC) demonstrated a 27 percent partial ... untreated patients with predominantly clear cell RCC. BAY 73-4506 (160 mg) was administered once ... studies to prevent the proliferation of tumor cell lines while promoting apoptosis (cell death) by ...

Keryx Biopharmaceuticals Reports Single Agent Phase 2 Data of KRX-0401 (Perifosine) Further Demonstrating KRX-0401's Activity in the Treatment of Advanced Metastatic Renal Cell Cancer

... for cancer, as a treatment for advanced renal cell carcinoma. Abstract #5034, entitled, "Phase II study of perifosine in metastatic renal cell carcinoma (RCC) progressing after prior therapy ... to patients with 2nd or 3rd line metastatic renal cell cancer. We are grateful to Dr. Vogelzang, Dr. ...

Video: Data on More Than 15 Novartis Oncology Compounds at ASCO Highlight Progress Toward Targeted Therapies for Diverse Tumor Types

... TKI258 (dovitinib lactate) in metastatic renal cell carcinoma (mRCC) patients refractory to approved ... study of heavily pre-treated metastatic renal cell carcinoma patients demonstrated that TKI258 500 ... of HSP90, a key target that regulates tumor cell survival and division, through the use of AUY922, ...

Fate Therapeutics Announces First Patient Treated in Phase 1b Clinical Trial of FT1050 for Hematopoietic Stem Cell Support

... Small Molecule Stem cell Modulator Administered in Dual Cord Blood ... clinical trial of FT1050, a small molecule Stem cell Modulator (SCM) designed to increase hematopoietic stem cell (HSC) number and function through its activation ...

Theranostics Health Announces Involvement with Major Academic Medical Center in Study Funded by Susan G. Komen for the Cure(R)

... fixatives are developed to both preserve cell morphology and fix the state of cellular ... analysis. LCM is used to isolate specific cell populations from many different types of cells ... subsequent molecular assays is specific to that cell population. RPMA enables sensitive, quantitative, ...

Ascenta Therapeutics Announces Multiple Presentations on AT-101 at 2009 ASCO Annual Meeting

... (T) in patients with relapsed or refractory small cell lung cancer (SCLC) after prior platinum ... #8582; Poster Board #S11; Lymphoma and Plasma cell Disorders, May 30, 8:00 a.m.-12:00 p.m. ... advanced solid tumors and extensive-stage small cell lung cancer (ES-SCLC). Abstract #e13502; ...
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(Date:10/29/2014)... is open for the Society of Interventional ... 2015 is the one place where interventional ... health care professionals can come together to ... technologies being presented, discussed and tested. ... invasive, image-guided medicine, SIR 2015 will feature ...
(Date:10/29/2014)... chemicals from household and industrial products are in the ... for most of them, scientists have yet to determine ... first step toward doing that by estimating which substances ... is published in the ACS journal Environmental Science ... note that the risks to human health of any ...
(Date:10/29/2014)... LANSING, Mich. – As bodies decompose, their types ... the clues they provide could mean the difference ... , Michigan State University is using a more ... help Detroit death-scene investigators examine these changing populations. ... as geographical location of death, gender, race, socioeconomic ...
Breaking Biology News(10 mins):SIR 2015: Interventional radiology shapes tomorrow's medicine 2MSU partners with Detroit to investigate death scenes 2
(Date:10/30/2014)... October 30, 2014 Paramount Rx, a ... is increasing efforts to help people save money through ... to increase for prescription drugs in the new health ... and resources to bridge the relationship between consumers, businesses ... the biggest challenges people face today with medical costs ...
(Date:10/30/2014)... HealthDay Reporter , WEDNESDAY, Oct. 29, ... prostate cancer who also have certain heart problems may increase ... study suggests. , , The therapy in question is called androgen ... levels of male hormones to prevent the growth of cancer ... this hormone therapy was linked to triple the risk of ...
(Date:10/30/2014)... Dennis Thompson HealthDay Reporter ... in Liberia -- one of three West African nations ravaged ... officials said Wednesday. Dr. Bruce Aylward, WHO,s assistant director ... burials in Liberia and no increase in laboratory-confirmed cases. He ... tame the epidemic may be making some progress, The ...
(Date:10/30/2014)... IL (PRWEB) October 30, 2014 Dr. Joseph ... a new website for his practices; OB GYN in ... IL . This website contains important information about each ... as well as downloadable patient forms in English and Spanish. ... and the service pages on the website provide Dr. Furlin’s ...
(Date:10/30/2014)... Francisco, California (PRWEB) October 30, 2014 ... billion by 2020, according to a new study by ... coupled with surging demand for sugar and fat free ... to augment the demand for prebiotics over the forecast ... http://www.grandviewresearch.com/industry-analysis/prebiotics-market , Food & beverage was the ...
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