Digital vs. Analog Mammography
...e, multicenter trial to compare the two for breast cancer detection. The Digital Mammographic Imaging Screening Trial (DMIST) will involve 49,500 women in the United and Canada and cost $26.3 million. It is designed to test what smaller, earlier trials have suggested: that digital mammography may provide be...PSA TestingHow Much is Too Much?
...been widely used as the gold standard for prostate cancer screening. In one of the most dramatic reversals i...er a man should even use the PSA test for prostate cancer screening any more, Stamey said. The researchers opinion carries great influence, since it was Stame...Genetic Analysis Systems Enter the Clinical Mainstream
...nal marketplace. The uses of these kits range from cancer detection and staging to human growth factor analysis to diabetes typing. Some of these kits have been approved for use in the U.S. and inevitably many more will become available in the future. PerkinElmer Life and Analytical Sciences, Inc., Boston, ...Testing for Human Papillomavirus
...and intermediate risk types detected in anogenital cancer biopsy specimens. Worldwide, HPV has been associa...y of any one HPV infection progressing to cervical cancer is quite small. Nevertheless, cervical cancer represents the second most common cancer in women, wi...Breast Cancer and HER-2/neu: Diagnostic Tools for Targeted Therapy
...0,000 new cases and 40,000 deaths per year, breast cancer undoubtedly qualifies as one of Americas most seri...t comes the promise of similar solutions for other cancer patients....Low-Density Cholesterol Subfractions: Not all LDL-C Particles are Created Equal
...s of cold medicine and the gold standard in breast cancer treatment have been challenged. Standards in cholesterol testing are the latest casualty of medical innovation. For years, cholesterol has been measured by a simple panel of high-density lipoprotein cholesterol (HDL-C), and low-density lipoprotein ch...Hematology Analyzers Simple, Sophisticated Technology Serving All Patients
... health, rule out anemia or infection, and monitor cancer patients during the course of chemotherapy. It is difficult to imagine medical care without this workhorse device, and surprising to learn its origins. Early testing of sonar, developed to detect submarines during World War II, revealed odd underwate...Data Available From Erbitux Phase III Study in First-Line Treatment of Advanced Lung Cancer
...t-linetreatment for metastatic non-small cell lung cancer (NSCLC). Thestudy did not meet its primary endpoin...ategy, are not yet available. "We consider lung cancer to be a high priority and await theresults of other Phase II and Phase III evaluations of ERBITUX in...Antisoma Announces Further Data From ASA404 Ovarian Cancer Trial
...ated. Based on these data, development in ovarian cancer will not be apriority. Antisoma has been testing ASA404 in several cancer types andpreviously reported a 5-month increase in median survival when thedrug was added to chemoth......the treatment of moderate to severepain, including cancer pain. YM previously announced that thistrial had s...the treatmentof moderate to severe pain, including cancer pain. In contrast tofixed-dose approaches to opioid delivery, where a significanttitration period is......ated portfolio of oncologyproducts aimed at making cancer more treatable. For additionalinformation, please visit <a target="_blank" href="http://www.cticseattle.com/">http://www.cticseattle.com . This press release includes forward-looking statements thatinvolve a number of risks and uncertainties...Protox Announces Positive Clinical Data from Prostate Cancer Study
...X302 in patients with localizedrecurrent prostate cancer who show signs of diseaseprogression as evidenced ...ed in the diagnosis of prostate cancer, monitoring cancer progression and tracking patientresponses to itstreatment. A comparison of prostate biopsies...Molecular Target of Bradmer's Neuradiab Further Validated by Independent Findings
...dicated to thedevelopment and commercialization of cancer therapies, todayannounced that new research publis...osely relatedtechnologies. Approximately 200 brain cancer patients, includingover 160 with GBM, have been treated with the Neuradiab therapyregimen, and survi......redtherapy selectively embeds a gene in pancreatic cancer that shrinksor eradicates tumors, inhibits metasta...a promising approach to gene therapy forpancreatic cancer and we are working to bring it to a clinicaltrial," says James Abbruzzese, M.D., professor and chair...Sunesis Pharmaceuticals to Present at the C. E. Unterberg, Towbin Emerging Growth Conference
...hroughinternal discovery and in-licensing of novel cancer therapeutics.Sunesis is advancing its product candidates through in-houseresearch and development efforts and strategic collaborations withleading pharmaceutical and biopharmaceutical companies. Foradditional information on Sunesis Pharmaceuticals, p...Micromet, Inc. to Present at the 3rd Annual C.E. Unterberg, Towbin Emerging Growth Conference
...ase 2a clinical trials, onein patients with breast cancer and the other in patients withprostate cancer. In addition, a phase 1b trial evaluating thesafety and tolerability of MT201 in combination with docetaxel iscurrently ongoing in patients with metastatic breast cancer.Micromet has established collabora...Array BioPharma to Present at the C.E Unterbeg, Towbin Emerging Growth Conference
...development pipeline is focused on thetreatment of cancer and inflammatory disease and includes clinicalcandidates that are designed to regulate therapeutically importanttargets. In addition, leading pharmaceutical and biotechnologycompanies collaborate with Array to discover and develop drugcandidates acro...Alfacell Corporation to Present at C.E. Unterberg, Towbin Emerging Growth Opportunities Conference
...velopment of a new class of targeted therapies for cancer andother life-threatening diseases. In addition to...hase I/II trial of ONCONASE in non-small cell lung cancer (NSCLC)and other solid tumors. For more information, visit <a target="_blank" href="http://www.a...ZIOPHARM to Present at C.E. Unterberg, Towbin Emerging Growth Opportunities Conference
...nd safety limitations ofapproved and developmental cancer therapies and identifiesproprietary and related molecules for better patient treatment. Formore information, visit www.ziopharm.com. Forward-Looking Safe Harbor Statement: This press release contains forward-looking statements forZIOPHARM Oncology,......r surgery or with a severe medical illness such as cancer orcardiopulmonary disease, particularly when accompanied by prolongedbed rest, age over 60, or a previous history of VTE. About COR (Center for Outcomes Research) The Center for Outcomes Research (COR) serves as the scientificcoordinating center fo...... synergistic effect of nimotuzumab andradiation on cancer cells and inhibition of EGFr down-streamsignaling ...n toinitiate trials with nimotuzumab in colorectal cancer and glioma,for which it has received No Objection letters from Health Canada.YM also recently announ......ge > 75 years orhistory of VTE or diagnosis of cancer and predefined acute medicalillness were randomized to received enoxaparin 40 mg subcutaneouslyonce daily for 10 plus or minus 4 days and were then randomized toreceive the same enoxaparin regimen or placebo for an additional 28plus or minus 4 days. ...Cougar Biotechnology Announces Presentation of Positive CB7630 Clinical Data at ESMO Conference
...Phase I and PhaseII data on the Company's prostate cancer drug candidate CB7630(abiraterone acetate) were pr...as part of the session forgenitourinary (prostate) cancer that took place. The posterpresentations are further detailed below: Inhibition of androgen synthesi...Pro-Pharmaceuticals Updates Progress of Clinical Trials & Davanat 505 (b)(2) Filings
...ne treatment of metastatic, unresectablecolorectal cancer patients who are unable to tolerate irinotecanand/... clinical trial for first-linetreatment of biliary cancer patients. Treatment for bothindications may represent orphan drug status for DAVANAT(R), theCompany'...MediGene Announces Cancer-Fighting Virus Shows Promise in Early Clinical Trial
...cientists to be safe to normal tissue butdeadly to cancer is showing early promise in a preliminary study,re... ongoing clinicaltrial in patients with colorectal cancer metastatic to the liver atthe meeting. Dr. Mescheder's poster presentation described the case of ...Positive ZIO-201 Interim Phase II Sarcoma Data Presented at European Society for Medical Oncology
...h is a pro-drug, ZIO-201 isdirectly active against cancer cells. Also, unlike IFOS, ZIO-201 isnot metabolize... a diverse,risk-sensitive portfolio of in-licensed cancer drugs to addressunmet medical needs. The Company applies new insights frommolecular and cancer biolo......prospective biomarker trial in non-small cell lung cancer - LOS ANGELES, July 09, 2007 /PRNewswire-FirstCall... patient biopsieswith advanced non-small cell lung cancer (NSCLC) predicts forsensitivity to cisplatin-based chemotherapy. ERCC-1 is an enzymeinvolved in repa......livery of leuprolide for the treatment of prostate cancer andendometriosis. Through its Biodefense Division, DOR is developing biomedicalcountermeasures pursuant to the recently enacted Project BioShieldAct of 2004. DOR's biodefense products in development arerecombinant subunit vaccines designed to protec......uding three additional studies inmetastatic breast cancer and one in non-small cell lung cancer. "Drug re... and its potential in patients withadvanced breast cancer that is no longer responding to any of thecurrent U.S. approved chemotherapy treatments." The 126 p......ntial for a new approach to the treatment ofbreast cancer using Proellex. The article reviews the findings f...ve showed asmall but clearly higher risk of breast cancer in women takinghormone replacement therapy that included a progestin. In the past, anti-progestin...Rosetta Genomics and Weizmann Institute Scientists Identify Role of microRNA in Cancer Suppression
...icroRNA (miR-34a) to be used as a drug candidatein cancer therapy to increase programmed cell-death (apoptos...or inhibitor thatcan prevent or slow the spread of cancer cells by facilitatingapoptosis. In this study, activation of p53 in-vivo in mice as wellas in cultur......izationof novel drugs for acute cardiovascular and cancer therapy.Nuvelo's development pipeline includes thr... which is in Phase 2 testing forpotential use as a cancer therapy, as well as NU206 for thepotential treatment of chemotherapy/radiation therapy-inducedmucosi...From Clinical Cancer Research: Rethinking Therapeutic Cancer Vaccine Trials
PHILADELPHIA, July 3, 2007-- Ongoing therapeutic cancer vaccinetrials have yet to show evidence of vaccine...hers asks afundamental question: are we looking at cancer vaccine trials thewrong way? “Cancer Vaccines: Moving Beyond CurrentParadigms,” Jeffrey...Skin Rash Actually Signifies Better Outcomes for Pancreatic and Lung Cancer Patients
... July 3, 2007-- – The appearance of arash in cancer patients treated with erlotinib (Tarceva) isstrong... more severe therash, the longer a patient’s cancer was held in check,researchers found. This rash, which often looks like acne, can be unpleasant ...Researchers Discover Method for Identifying How Cancer Evades the Immune System
...e such analysis could become a standardpractice in cancer diagnosis and treatment. “The implication ...l variations. Their differencesvary widely between cancer types, even between subcategories withina particular type of cancer. However, while the genetic vari...Fat Kills Cancer: Turning Stem Cells from Fat Tissue into Personalized, Cancer-Targeted Therapeutics
...lso found in the mass of normalcells that mix with cancer cells to make up a solid tumor.Researchers believe...nst Cancer, and support from theSlovakian national cancer genomics program. # # # The mission of the American Association for CancerResearch is to preve......with atypia have a higher absolute risk for breast cancer thanpreviously estimated. This risk is 25 percent ...age 45) more than twice as likely todevelop breast cancer compared to women diagnosed with atypia after55. The number of areas of atypical hyperplasia was sig...... novel drugs inthe therapeutic areas of infection, cancer and inflammation. TheCompany's lead candidate, cethromycin, is a novel once-a-dayantibiotic in late-stage clinical development for the treatment ofrespiratory tract infections including CAP. For more information,please visit us on the web at <a t......gnancy and although the disease is predominantly a cancer ofthe elderly (the average age of onset is 65 to 70 years of age),recent statistics indicate both increasing incidence and youngerage of onset. In the U.S., more than 50,000 individuals have MM and20,000 new cases are diagnosed each year. Worldwide t......livery of leuprolide for the treatment of prostate cancer andendometriosis. Through its Biodefense Division, DOR is developing biomedicalcountermeasures pursuant to the recently enacted Project BioShieldAct of 2004. DOR's biodefense products in development arerecombinant subunit vaccines designed to protec...... novel drugs inthe therapeutic areas of infection, cancer and inflammation. TheCompany's lead candidate, cethromycin, is a novel once-a-dayantibiotic in late-stage clinical development for the treatment ofrespiratory tract infections including CAP. For more information,please visit us on the web at <a t...Vaccine Can Prevent Cervical Cancer and Precancerous Lesions
LONDON, June 28, 2007--A cervical cancer vaccine has shown 90%efficacy for prevention of cervical cancer and precancerous lesionsassociated with the human papillomavirus (HPV) types targeted bythe vaccine,...RTA 402 Shown to Protect Animals Against Toxicities of Standard Cancer Treatments
...ing againstcommon toxicities caused by traditional cancer treatments. Thisdata was presented at the annual m...n with radiation therapy to ratsbearing human lung cancer tumors, the drug protected non-canceroustissue from radiation damage while simultaneously enhancing ...Cytokinetics Reports Additional Clinical Trials Data for Ispinesib
...totic kinesins for applications inthe treatment of cancer and other diseases. All threeclinical trials were...lyadvanced, recurrent or metastatic hepatocellular cancer wasrecently completed. In Stage 1 of this two-stage clinicaltrial, 15 patients received ispinesib a......port from the ongoing clinical trial of MediGene's cancer killingvirus will be presented in a press conferen...for the treatment of livermetastases of colorectal cancer is being conducted at seven leadingcancer centers in the US. In September 2006, MediGene announcedpo......ted Akt (pAkt) are seen frequently in manytypes of cancer and have been correlated with poor prognosis inpat...ul in combination to reducethe resistance to other cancer treatments. To date, over 1,500 patients have been treated with perifosinein trials conducted both ...Biotec Pharmacon Announces Preliminary Results from the Sloan-Kettering Clinical Study
...2007-Preliminary results fromthe immunotherapeutic cancer study at Memorial Sloan-KetteringCancer Center sho...file for SBG. Furthermore,encouraging responses on cancer development have been observedamong several patients that have been treated with SBG incombination w......eting in Kos." Multiple myeloma is a rare form of cancer of plasma cells. It isthe second most common cancer of the blood, affecting over 80,000people in Europe and an estimated 750,000 worldwide at any onetim......any is focused on the areas of infectiousdiseases, cancer and inflammatory diseases. With more than 2,500employees worldwide, MedImmune is headquartered in Maryland. Formore information, visit the company's Web site at <a target="_blank" href="http://www.medimmune.com/">http://www.medimmune.com . A......gress we've begun inmyeloma is encouraging for all cancer patients around theworld." Myeloma, also called multiple myeloma, is a cancer of cells inthe bone marrow that affects production of red cells, white cellsand stem cells. It affec......gnancy and although the disease is predominantly a cancer ofthe elderly (the average age of onset is 65 to 70 years of age),recent statistics indicate both increasing incidence and youngerage of onset. In the U.S., more than 50,000 individuals have MM and20,000 new cases are diagnosed each year. Worldwide t......gnancy and although the disease is predominantly a cancer ofthe elderly (the average age of onset is 65 to 70 years of age),recent statistics indicate both increasing incidence and youngerage of onset. In the U.S., more than 50,000 individuals have MM and20,000 new cases are diagnosed each year. Worldwide t......show thatCERVARIX(R), the GlaxoSmithKline cervical cancer candidate vaccine,provides up to 100 percent prote...rth America, making it the single largest cervical cancer vaccineefficacy trial to date. Cross protection In this clinical trial, the vaccine showed signifi...... ofdarinaparsin for the treatment of primary liver cancer and diversehematological cancers. Phase I trials w... a diverse,risk-sensitive portfolio of in-licensed cancer drugs to addressunmet medical needs. The Company applies new insights frommolecular and cancer biolo......rcializing innovative products, likeQUADRAMET, for cancer patients, and these results support ourongoing dev...on. About Multiple Myeloma Multiple myeloma is a cancer of the bone marrow in which whiteblood cells called plasma cells, normally responsible for theproduc...... (PSMA), a protein found on thesurface of prostate cancer cells. Progenics also is developingvaccines design... clinical testing. The Companyalso is developing a cancer vaccine, GMK, in phase 3 clinicaltrials for the treatment of malignant melanoma. PROGENICS DISCLOSU...Cytochroma Reports Positive Phase I Clinical Data for CTA018 Injection
...pies to treathyperproliferative disorders, such as cancer and psoriasis, andhyperphosphatemia CONTACT: Eric J. Messner, Vice President, Commercial Operations,(905)479-5306 ext. 338, <a target="_blank" href="mailto:eric.messner@cytochroma.com">eric.messner@cytochroma.com Terms and conditions of u......iety of vascular diseases andconditions related to cancer and cancer treatments. Defibrotide,the Company's lead product candidate, is an investigational drugthat has bee......on treatments involve theoff-label use of existing cancer drugs such as cyclophosphamide,steroids, and immun...r in diagnostics, the leading supplierof drugs for cancer and transplantation and a market leader invirology. In 2006, sales by the Pharmaceuticals Division t......ential application for ONCONASEin various types of cancer other than the gateway indication formesothelioma,...tance in various tumor types." Neuroblastoma is a cancer that forms in the nerve tissue. It isthe most common cancer in infants, and the fourth most common t...