calcium

New Point-of-Care Methods to Measure Coronary and Cerebrovascular Risk

...ation, which combines with lipid, cholesterol, and calcium deposition to form plaques. These plaques accumulate over time, narrow the lumen inside the artery, and limit blood flow to distal structures such as the myocardium and brain. A plaque may also break and liberate pieces that block distal arterial b...

BioSante Pharmaceuticals Announces New Findings for Potential Bird Flu Vaccine

...nounced new positiveresults demonstrating that its calcium phosphate (CaP)nanoparticle-based vaccine adjuvant...ly $3.0 billion. The company also isdeveloping its calcium phosphate nanotechnology (CaP) for novelvaccines, including hepatitis B, avian flu and biodefense va...

TransPharma Medical Announces Positive Results of Phase I Clinical Trials for Transdermal Delivery of hPTH (1-34) for Osteoporosis Treatment

...taneous injection. All safety parameters(including calcium and phosphorous) of the different transdermaldoses were within the normal range. Furthermore, all ViaDerm-hPTH(1-34) doses were very well tolerated by participants. Pharmacokinetic profiles of hPTH (1-34) in the first and seventhday were similar, sh...

Cytochroma Reports Positive Phase I Clinical Data for CTA018 Injection

...urine calciumor in serum phosphorus. Serum ionized calcium levels also remainedunchanged. We believe that the PTH-lowering effect of CTA018 willbe even more pronounced in CKD patients with secondaryhyperparathyroidism." About CTA018 CTA018 is the first compound in a new class of active Vitamin Danalogs hav...

New Proof of Genistein's Efficacy and Safety for Osteopenia and Osteoporosis Published in Annals of Internal Medicine

...sity. -- Patients taking genistein in addition to calcium and vitaminD showed a gain in bone density of appr...hlypurified genistein isolated from soy along with calcium and vitaminD. Principle Investigator for the study, Francesco Squadrito, M.D.,Professor of Pharmacol...

Elixir Pharmaceuticals Presents Preclinical Data Highlighting Its Ghrelin Antagonist Program at the American Diabetes Association's Annual Meeting

...nd SouthAmerican rights to Glufast(R) (mitiglinide calcium hydrate), aninsulin secretagogue, which lowers post-meal glucose levels byimproving the body's own ability to produce insulin. Alreadymarketed in Japan, Glufast has undergone extensive clinicaldevelopment demonstrating the product's ability to safely...

New Analysis of WHI Data Shows Reduced Levels of Coronary Artery Calcification, a Predictor of Cardiovascular Events, in Women aged 50-59 taking Estrogen Therapy

...ly $3.0 billion. The company also isdeveloping its calcium phosphate nanotechnology (CaP) for novelvaccines, including hepatitis B, avian flu and biodefense vaccinesfor toxins such as anthrax, as well as a system for deliveringdrugs via alternative routes of administration. Additionalinformation is available...

New Data Presented on Micardis (Telmisartan) Tablets in Hypertensive Patients With Type 2 Diabetes

...other non-ARB treatments (hydrochlorothiazide or a calcium channelblocker) were added, if needed. No significant difference in blood pressure control or number ofadverse events was observed between the two treatmentgroups.(1) After treatment of one year, 24 hour protein excretion measuredby spot protein to...

New Study Shows That telmisartan has Greater Renoprotective Potential Thanlosartan in Hypertensive Patients With Type 2 Diabetes

...s other non- ARB treatments(hydrochlorothiazide or calcium channel blocker) were added,if needed. After one year's treatment, telmisartan was significantly moreeffective than losartan in reducing the amount of proteinexcreted in the urine. The primary end point of the study wasreduced by 29% with t...

Genzyme Announces Results of Clinical Trials Investigating Powder Form of Sevelamer Carbonate

...phate binder available thatdoes not contain either calcium or a metal. It has an establishedsafety profile, i...providesphosphorus control without the concerns of calcium or metalaccumulation. Renagel is used by more than 350,000 peopleworldwide. Renagel is indicated fo...

Genzyme Announces Results of Clinical Trials Investigating Powder Form of Sevelamer Carbonate

...phate binder available thatdoes not contain either calcium or a metal. It has an establishedsafety profile, i...providesphosphorus control without the concerns of calcium or metalaccumulation. Renagel is used by more than 350,000 peopleworldwide. Renagel is indicated fo...

Gabapentin Shown Effective for Fibromyalgia Pain

...f gabapentin to a specificsubunit of voltage-gated calcium channels on neurons. This bindingreduces calcium flow into the nerve cell, which reduces the releaseof some signaling molecules involved in pain proc...

Elixir Pharmaceuticals Presents Additional Preclinical Data Demonstrating the Potential of Ghrelin Antagonism to Regulate Metabolism, Body Weight and Glycemic Control

...nd SouthAmerican rights to Glufast(R) (mitiglinide calcium hydrate), aninsulin secretagogue, which lowers post-meal glucose levels byimproving the body's own ability to produce insulin. Alreadymarketed in Japan, Glufast has undergone extensive clinicaldevelopment demonstrating the product's ability to safely...

Phase 2 Clinical Results of Ganite Plus Standard Therapy in Patients with Relapsed/Refractory Lymphoma Presented at ASCO

...s showed that the drug markedlyreduced the loss of calcium from bone - an observation that suggested the drug may be useful inhypercalcemia, as well as other conditions associated with loss of bone mass. Ganite isapproved in the U.S. for treatment of symptomatic patients with cancer related hypercalcemia tha...

Amlodipine and Olmesartan Study Results Released;Late Breaker Presented at American Society of Hypertension Twenty-Second Annual Scientific Meeting (ASH 2007)

... PARSIPPANY, NJ(May 21, 2007) -- Combining the calcium channel blockeramlodipine besylate with the angiot...ntary mechanisms of action to lower bloodpressure: calcium channel blockade with amlodipine and angiotensinreceptor blockade with olmesartan. <p style="M...

New Data Highlights Potential of SPP100 (Tekturna) as Gold Standard Therapy in Treatment of Hypertension

...iren alone or in combination witha diuretic and/or calcium channel blocker in Japanese patients withhypertension is well tolerated and provides effective bloodpressure reductions that are maintained over 52 weeks oftreatment. Aliskiren in combination with hydrochlorothiazide is effectiveand well tolerated d...

SkyePharma and Sciele Pharma Announce Successful Completion of New Sular Formulation Clinical Trial Programme

...trial programmefor the new formulation of Sular, a calcium channel blocking agent for the treatment of high b...pportunity for better treatments. Nisoldipine is a calcium channel blocker thatprevents calcium from entering certain types of muscle cells.Because muscle cell...

Once-yearly Reclast Significantly Reduced Bone Fractures in Women with Postmenopausal Osteoporosis

...nts with Paget's diseaseshould receive 1,500 mg of calcium in divided doses and 800 IU ofvitamin D daily, particularly in the two weeks following Reclastadministration. Reclast is not recommended for use in patients withsevere renal impairment (creatinine clearance <35mL/min). Themost common side effects...

Genzyme Announces Successful Completion of Study Investigating Sevelamer Carbonate in Patients With Chronic Kidney Disease

...phate binder available thatdoes not contain either calcium or a metal. It has an establishedsafety profile, i...providesphosphorus control without the concerns of calcium or metalaccumulation. Renagel is used by more than 350,000 peopleworldwide. Product Information Re...

New Analysis of Data from WHI Provides Reassurance With Respect to Coronary Heart Disease For Newly Menopausal Women Considering Hormone Therapy

... toevaluate hormone therapy, dietary modification, calcium and vitaminD as preventive therapies for menopausal women. The hormone therapyarms were designed to assess select long-term risks and benefits ofhormone therapy. The WHI studied conjugated estrogens (0.625 mg)(PREMARIN(R) [conjugated estrogens tablet...

Calcium Channel Blocker Adalat GITS Offer Additional Benefits

...defurther evidence that the use of the long-acting calcium channelblocker (CCB) nifedipine GITS (Adalat? GITS) has additionalbenefits beyond its blood pressure lowing effect. A firstpublication from Lubsen et al. (Journal of Clinical Epidemiology2007; first published online) demonstrates that while the blood...

Pivotal Phase III Findings With Investigational Drug Cleviprex (Clevidipine) Demonstrate Perioperative Blood Pressure Control In Cardiac Surgery

...t. It is the first third-generationdihydropyridine calcium channel blocker that acts rapidly andreliably, is vascular- and arterial-selective, and has anultrashort half-life. Cleviprex recently completed Phase IIIclinical trials. MDCO-G About The Medicines Company The Medicines Company is committed to del...

Landmark Findings From ECLIPSE Program Show Improved Control of Perioperative Hypertension Reduces Risk of Death In Cardiac Surgery

...t. It is the first third-generationdihydropyridine calcium channel blocker that acts rapidly andreliably, is vascular- and arterial- selective, and has anultrashort half-life. Cleviprex recently completed Phase IIIclinical trials. MDCO-G About The Medicines Company The Medicines Company is committed to de...

Calcium Plaque Build-up in the Arteries Leads to Coronary Heart Disease in Multi-Ethnic Groups

...s studies have shown thatincreased coronary artery calcium is linked to greater risk ofheart disease events a...anicsand Chinese — even though the amount of calcium build-up inthese populations is low relative to Caucasians. MESA evaluated 6,814 men and women with...

REACH Registry Demonstrates That Multiple Arterial Disease Locations Sharply Increase the Risk of Major CV Events in Outpatients With Atherothrombosis

...el. Plaquesconsist of fatty acids and cholesterol, calcium and othermaterials. The rupture of plaques and the subsequent development of a clotcan cause partial or complete blockage of an artery in variousparts of the body. When a vessel in the heart is partially orcompletely blocked by a clot the result can...