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Dade Behrings (hsCRP) Tests and BNTM Series Analyzers

...de Behrings CRP test can be run using either whole blood or plasma and requires nephlometric systems (such ...ments: Dade Behringers hsCRP test requires 1 mL of blood or plasma serum (minimum of 0.5 mL) at room temperature when it is run. The sample can be refrigerat...

Monitoring Patient Glucose Levels: New Advances in software make it easier

...systems in recent years. Painless or near painless blood and fluid sampling systems such as Minimeds contin..., the Accu-Chek Complete and the Accu-check Active blood glucose monitors as well as hand-held PDAs. Roche has created Compass Diabetes Care Software, and a...

Point of Care Strep Tests Speed Treatment, Lower Costs

...he isolation and identification of the organism on blood agar plates. These methods usually require 18-24 hours of incubation at 37C. This delay in identifying group A streptococcus has often caused physicians to administer therapy without first knowing the etiological agent. Alternatively, the development...

Rapid Whole Blood Testing for Infectious Mononucleosis Antibodies

...ings include a normal to moderately elevated white blood cell count, an increased total number of lymphocyt...r both CLIA-moderate (using serum, plasma or whole blood specimens) and waived labs (using whole blood specimens only). The test uses color immunochromatogra...

PSA TestingHow Much is Too Much?

...Test designed to detect PSA concentration in whole blood or serum in concentrations as low as four ng/ml wi...ncer Test collection kit that includes a fingertip blood sample stylet, specimen card. The user sends the prepaid mailer to the companys laboratory where it ...

Bench-Top Centrifuges--Basic Tools for the Small Lab

...l choice for routine, low-volume centrifugation of blood and urine. Each Medilite comes complete with a 45-degree angle rotor and a full set of standard shields. The device is designed with an integral 30-minute timer and accepts a variety of tube sizes up to 15 mL. This centrifuge also features a mainten...

Monitoring Options Expand for Therapeutic Agents and Drugs of Abuse

...improved clinical outcomes derived from monitoring blood levels of drugs that were administered to control epileptic seizures. The determination of blood levels guided dosage adjustment until optimal drug levels were achieved. Today, therapeutic drug m...

Prothrombin Time Comes in Small (CLIA-Waived) Packages

... A single drop (10 l) of capillary or venous whole blood is applied to a test strip containing thromboplast...rocoagulation System, which uses fingerstick whole blood samples and displays test results as INR and PT interval in four to five minutes. It consists of a P...

Analyzers Offer Point-of-Care Lipid Panels

...o measure a range of lab values from a fingerstick blood sample. Result processing takes about five minutes...e of in-office tests on a single fingerstick whole blood sample. As with the Cholestech analyzer, the CardioChek product can perform a variety of tests, depe...

Hemoglobin Testing at the Point of Care

Since the level of blood oxygenation can be an essential element of patient...te collects the exact amount of arterial or venous blood necessary (10 l). The cuvette cavity contains reagents deposited on its inner walls and the blood sa...

Point of Care Cardiac Analyzers Yield Rapid Cardiac Marker Results

...int of care (POC) assays that directly assay whole blood provide an attractive alternative to central lab t...nation of CK-MB, myoglobin and troponin I in whole blood and plasma specimens using EDTA as the anticoagulant. To perform the test, a blood sample is added ...

West Nile Virus Screening and Diagnostics Technology Emerges In Step with North American Outbreak

...s explain the rationale for screening asymptomatic blood donors with nucleic acid-amplification tests (NAT)...toes, transmission has occurred through transfused blood products. Since 2003 donor mini-pools have been tested by NAT utilizing two test manufacturers appr...

Tight Glycemic Control in the ICU

...re is ongoing debate and research on what level of blood glucose is optimal, and whether the benefits to patients result solely from lower blood glucose, or from the broad physiological effects of insulin, or from both, glycemic control protocol...

The Past, Present and Future of HLA Typing

...us women, or individuals who had received multiple blood transfusions. In addition, polymorphisms in Class II proteins were analyzed by T-cell responses in the Mixed Lymphocyte Reaction (MLR). However, the advent of recombinant DNA technology, which paved the way to identifying genetic differences among ...

New Assays to Detect Disseminated Fungal Infections

... Aspergillus lesion), a mainstay of diagnosis is blood cultures, which have suboptimal speed and sensitiv... Fungitell is prepared from lysed amebocytes (crab blood cells), which are treated to remove the factor C (lipopolysaccharide-dependent) pathway and restrict...

Gene Chips to Detect CYP Variations: A New Step Toward Customized Medical Therapy.

... a particular medication. In the former scenario, blood concentrations and the risk of side effects can ri...bed above, these patients are at risk for abnormal blood concentrations: poor metabolizers may develop serious side effects, and extensive or ultra-rapid met...

Appendicitis: Evolving Tools to Diagnose a Classic Disease

...of suspected appendicitis, where an elevated white blood cell count (WBC) is a classic but nonspecific feat...hils and some monocytes. When introduced into the blood stream, the antibody attaches to neutrophils, which then travel to the infected appendix. The antib...

New Point-of-Care Methods to Measure Coronary and Cerebrovascular Risk

...ually hypertension, which contributes to turbulent blood flow that traumatizes the intimal surface. Anothe...ime, narrow the lumen inside the artery, and limit blood flow to distal structures such as the myocardium and brain. A plaque may also break and liberate pi...

Managing Preanalytical Processes for Patient Safety

... We used to have two different procedures, one for blood bank specimens and one for other specimens. It hel...gle procedure. You can harm a patient with a wrong blood draw for a chemistry specimen just as you can for a blood bank specimen." To prevent these issues, a...

Low-Density Cholesterol Subfractions: Not all LDL-C Particles are Created Equal

...bution, by nuclear magnetic resonance spectroscopy blood test. The LipoProfile identifies the average size of LDL particles (in units of nanomoles of particles per liter), linking a greater distribution of small particles with the greatest risk for developing CHD and Type 2 Diabetes Mellitus. Patients with...

Diagnosing Diabetes: Immediate HbA1c Results Improve Glycemic Control

... Type 2, and gestational) marked by high levels of blood glucose resulting from defects in insulin producti...or HbA1c, as the best way to determine a patient's blood glucose control over the past 2-3 months. Specifically, the test measures the concentration of glyco...

Hematology Analyzers Simple, Sophisticated Technology Serving All Patients

...und at the center of most clinical laboratories. A blood cell count is usually the first screening test use...ical impedance to classify and count red and white blood cells based on their size. Improvements to the application of electrical impedance include pulse edi...

Blood Gas Analysis: The Pros and Cons of Point-Of-Care Testing

...tor Since the first system was invented in 1957, blood gas analysis has revolutionized clinical medicine and patient care. During the 1960s, blood gas analysis became almost universally available, and blood gases were considered "the most importan...

Rapid HIV Testing Increases Possibility of Treatment

...etect antibodies to HIV-1 using finger stick whole blood or venipuncture whole blood specimens. The updated OraQuick ADVANCE Rapid HIV-1/2 Antibody Test FDA approved in October 2004,...

Near-Patient Testing: The Advantages of C-Reactive Protein in Hematological Testing

...bsequent threat of infection and possible need for blood transfusion. Aplasia: Bone marrow aplasia is con...an observed drop in CRP levels and a rise in white blood cells (WBC) can allow an earlier patient discharge. The combination of CRP and CBC analyses can the...

Phase 3 Results for Dabigatran Etexilate, an Investigational Oral Anticoagulant, Presented Today at the XXIst Congress of the International Society on Thrombosis and Haemostasis

...nd reversibly inhibits thrombin, thekey enzyme for blood clot formation, and is currently in phase 3development. It is administered as a once daily oral dose that doesnot require titration or coagulation monitoring. Further studies investigating dabigatran etexilate Dabigatran etexilate is being investig...

Positive Aggrastat Results Featured in the Journal of the American College of Cardiology

...ted in patients with:severe hypertension (systolic blood pressure greater than 180 mmHgand/or diastolic blood pressure greater than 110 mmHg); concomitantuse of another parenteral GP IIb/IIIa inhibitor; or acut...

Clinical Data Suggest Decreased Bleeding Risk in People With Severe Hemophilia A While Maintaining Factor VIII Levels Above One Percent

...uate amounts offactor VIII, which is necessary for blood to effectively clot. Ifuntreated, patients with se... factor VIII in the blood,thus allowing the body's blood clotting process to properlyfunction. ADVATE is the only recombinant factor VIII therapyprocessed wi...

Pixantrone Combination Therapy for First-line Treatment of Aggressive Non-Hodgkin's Lymphoma Results in Reduction in Severe Toxicities Including Heart Damage When Compared to Doxorubicin-based Therapy

...ection while the patient'sinfection-fighting white blood cells are low due to neutropenia.The RAPID study is expected to complete enrollment in 2008. "We are excited by these results demonstrating that pixantroneis living up to the promise of preventing the severe cardiac damagethat accompanies the use ...

Protox Announces Positive Clinical Data from Prostate Cancer Study

...arkers in prostate cancerand levels of PSA in the blood are used in the diagnosis of prostate cancer, monitoring cancer progression and tracking patientresponses to itstreatment. A comparison of prostate biopsies taken at baseline and at 30days post-treatment shows that 18 of the 24 patients test...

ViaCell to Present at the C.E. Unterberg, Towbin Emerging Growth Opportunities Conference

...h families canpreserve their baby's umbilical cord blood at the time of birth forpossible future medical use in treating over 40 diseases includingcertain blood cancers and genetic diseases. ViaCell also conductsresearch and development primarily to investigate...

International ENDORSE Study Shows That the Majority of Hospitalized Patients Surveyed are at Risk for VTE and Many do not Receive Recommended VTE prophylaxis

... a general term used to describe theformation of a blood clot (thrombus) that blocks a vein. This mayoccur in any part of the venous system, but the most commonmanifestations are deep-vein thrombosis (DVT), usually in the leg,and pulmonary embolism (PE). VTE is a common complication among patients hospita...

AM-Pharma Announces Positive Results of Phase IIa Clinical Trial with Alkaline Phosphatase For Ulcerative Colitis

... composed of 6 variables:number of stools per day; blood in stools; temperature; pulse;haemoglobin; and erythrocyte sedimentation (ESR) rate. Response isdefined as a TLW score of less than 10 and by a decrease of 3points or more. Clinical remission was defined as a TLW score ofless than 3, which means 1 or...

Phase III Trial Results Show Superiority of Rivaroxaban over Enoxaparin for the Prevention of Venous Thromboembolism in Patients Undergoing Knee Replacement Surgery

...anticoagulant (a drug designed toprevent and treat blood clots) in advanced clinical development forthe pre...ic disease, which is causedby the obstruction of a blood vessel by a blood clot, is a leadingcause of global mortality and a concern for many patientpopulati...

New Study Shows That Extending Prophylaxis With Clexane / Lovenox (enoxaparin Sodium Injection) to 5 Weeks is More Effective Than 10 Days for Reducing the Risk of Venous Thromboembolism (VTE) in Acutely ill Medical Patients With Reduced Mobility

... a general term used to describe theformation of a blood clot (thrombus) that blocks a vein. This mayoccur in any part of the venous system, but the most commonmanifestations are deep-vein thrombosis (DVT), usually in the leg,and pulmonary embolism (PE). VTE is also a common complication among acutely-ill...

Phase III Trial Results Show Superiority of Rivaroxaban over Enoxaparin for the Prevention of Venous Thromboembolism in Patients Undergoing Knee Replacement Surgery

...nticoagulant - a drug designed toprevent and treat blood clots - in advanced clinical developmentfor the pr...icdisease, which is caused by the obstruction of a blood vessel by ablood clot, is a leading cause of global mortality and a concernfor many patient populati...

MediGene Announces Cancer-Fighting Virus Shows Promise in Early Clinical Trial

...irus treatment infour weekly infusions direct into blood stream, followed by twocycles of approved chemotherapy. Six months after treatment, scans showed the liver masses hadnearly disappeared. "The reduction in the tumor masses was reallyimpressive in this patient," Dr. Mescheder said. "The hepaticmasses...

Cobalis Reports Phase III Trial Results for PreHistin in Seasonal Allergic Rhinitis

...obalamin. A comparison of pre- and post-treatment blood levels ofcobalamin demonstrated for the first time...ngesresulted in significant increases in cobalamin blood levels. Cobalis' Chief Scientific Officer Ernest Armstrong commented:"Showing a meaningful reductio...

DOR BioPharma Announces Issuance of European Patent for Its Oral Multivalent Botulinum Toxin Vaccine BT-VACC

...eis safe and stimulates antibodies in not only the blood but thoseantibodies that coat mucosal surfaces. It is thought thatantibodies that are present in lung and gastrointestinal secretionswill block the uptake of the toxin before entering the bloodstreamand reaching peripheral nerves. About Botulinum To...

Beike Biotechnology Study Suggests Adult Stem Cells Show Promise for Peripheral Vascular Disease

Adult stem cells cultivated from patients' own blood canpotentially improve the quality of life for pat...y, and feasibility of transplantation ofperipheral blood stem cells for patients with peripheral vasculardisease of the lower extremities. Beike is best kno...

DOR BioPharma Announces Publication Describing Results of Its Multivalent Botulinum Toxin Vaccine BT-VACC

...e is safeand stimulates antibodies in not only the blood but thoseantibodies that coat mucosal surfaces. It is thought thatantibodies that are present in lung and gastrointestinal secretionswill block the uptake of the toxin before entering the bloodstreamand reaching peripheral nerves. BT-VACC™ orig...

Chi-Med Announces Positive Phase II Proof-of-Concept Data for HMPL-004 in Ulcerative Colitis

...rface withconsequential pain, loss of function and blood loss. Thedisease can require surgical removal of sections of the gut and, inextreme cases, it may cause death. Crohn’s Disease displayssimilar but more severe laceration of the lining of the smallintestine. Current firstline treatments have...

Common Preterm Labor Drug Has More Side Effects Than Alternative, Finds Study from Packard Children's Hospital and Stanford

...eadaches. Nifedipine iscommonly used to treat high blood pressure and heart disease. "The take-home message is that we saw no differences in relevantoutcomes between the two groups," said Lyell, "but there was asignificant difference in the side effects experienced by thewomen, and some of these were very...

Based on Up to 6 Years of Follow-Up, Biovest Announces Favorable Interim Blinded Data for Fast-Tracked Pivotal Phase 3 Clinical Trial of BiovaxID Anti-Cancer Vaccine for Non-Hodgkin's Lymphoma

...immunotherapies for life-threateningcancers of the blood system. Biovest is a majority-owned subsidiaryof Accentia Biopharmaceuticals, Inc., (NASDAQ:ABPI) with itsremaining shares publicly traded. Biovest has a foundation in themanufacture of biologics for research and clinical trials. Inaddition, Biovest ...

Cytogen Presents Phase 1 Data Showing Promising Antitumor Activity and Safety Profile of Quadramet at International Myeloma Workshop

... bone marrow suppression. In clinical trials,white blood cell counts and platelet counts decreased to a nad...causes decreased productionof normal red and white blood cells, and of normal disease-fightingantibodies, as well as the growth of tumors that spread to mult...

Cytochroma Reports Positive Phase I Clinical Data for CTA018 Injection

...events werereported. Significant reduction in the blood levels of parathyroid hormone(PTH) was observed in this trial, suggesting that CTA018 haspotential as a treatment for secondary hyperparathyroidism inchronic kidney disease (CKD). Blood samples collected before andafter repeated CTA018 administration...

Speedel Reports Successful SPP635 Phase IIa Trial in Hypertension

...s in laboratory safety parameters.Sitting systolic blood pressure was significantly reduced by 17.9mmHg fro...8.9 mmHg; baseline vs. end oftreatment). Diastolic blood pressure was also significantly reducedby 9.8 mmHg from 91.3±7.8 to 81.5±8.2 mmHg(p...

A 4-Week Therapy with Transition Therapeutics' E1-I.N.T. Leads to Sustained Reductions in Blood Glucose Levels for 6 Months Post-treatment in Type 2 Diabetes Patients

...rapy, E1-I.N.T.(TM), showedsustained reductions in blood glucose control parameters, includinghaemoglobinA1...uctions, the data demonstrated decreasesin fasting blood glucose levels as well as improvements in glucosetolerance over a six month period following treatme...

Opexa Advances Monocyte Derived Islet Technology to Proof of Principle in stz-induced NOD/SCID Mice

...ate a prolonged reduction(greater than 60 days) in blood glucose levels when MDIs weretransplanted under the kidney capsule of stz-induced NOD/SCIDmice. The second presentation, also made by Dr. Winnier, was presentedat the ISCT Annual Meeting in Sydney, Australia. The Company'srecent adult stem cell re...

Bio-Matrix Scientific's Dr. O'Neill Sees University of Pittsburgh's Published Study on Culture Blood-Forming Stem Cells from Human Fat Tissue as Supporting Near Term Benefits of Banking Adipose (Fat) Derived Stem Cells

...patientsundergoing intensive radiation therapy for blood cancers." "This recent announcement by Researchers...ttsburgh School of Medicine that hematopoietic, or blood formingstem cells, can be isolated from fat, or adipose tissue, could havea major impact on the acce...

Columbia Laboratories Reports Positive Results from Multi-dose Pharmacokinetic Study of Vaginally-administered Lidocaine

...tion over four consecutive days wasassociated with blood levels that are well within an acceptedrange," sta...search and development. "At the highestdose, those blood levels are what we anticipated based onextrapolation of data from the prior, single-administrationph...

Genetics Journal Thimerosal/Autism Study the 'Best Science Drug Company Money Can Buy'

...ried to clearthimerosal as harmful by conducting a blood mercury evaluationafter infant vaccination which missed peak blood levels, had asample size too small to detect susceptible subgroups, and failedto address implication...

Data Demonstrated Saxagliptin Added to Metformin Improved Glycemic Control in Subjects with Type 2 Diabetes Compared to Metformin Alone

...plications,including heart disease or stroke, high blood pressure, amputation(particularly legs), blindness...e. The goal ofthose with diabetes is to keep their blood glucose levels as closeto normal as possible. This helps to minimize the complicationscaused by chro...

Insmed Inc. Welcomes Studies Linking IGFBP-3 to Prevention of Blindness in Premature Infants

...each year. ROP impedesthe development of the small blood vessels in the back of the eye,leading to blindness in severe cases. A Phase I clinical studyinvestigating IPLEX(TM) as a treatment for ROP is underway at theUniversity of Goteborg, in collaboration with scientists at theHarvard Medical School. Ten p...

Data Demonstrated Saxagliptin Added to Metformin Improved Glycemic Control in Subjects with Type 2 Diabetes Compared to Metformin Alone

...plications,including heart disease or stroke, high blood pressure, amputation(particularly legs), blindness...e. The goal ofthose with diabetes is to keep their blood glucose levels as closeto normal as possible. This helps to minimize the complicationscaused by chro...

An Investigational Study Released at ADA Showed that Initial Combination Therapy with Januvia (sitagliptin) and Metformin Led to Improvement in Markers of Beta Cell Function in Patients with Type 2 Diabetes

..., another hormone that is animportant regulator of blood sugar levels. This aspect of themechanism of actio...Across clinical studies, a small increase in white blood cellcount (approximately 200 cells/microL difference in WBC vs placebo;mean baseline WBC approximate...

First Phase II Short-Term Study on Dapagliflozin Shows Results on Safety, Tolerability and Glycemic Markers in Subjects With Type 2 Diabetes

...plications,including heart disease or stroke, high blood pressure, amputation(particularly legs), blindness...e. The goal ofthose with diabetes is to keep their blood glucose levels as closeto normal as possible. This helps to minimize the complicationscaused by chro...

Neuroblastoma Expert Reviews Progress and Challenges in Fighting Difficult Pediatric Cancer

...lls,angiogenesis inhibitors that cut off a tumor's blood supply, andtyrosine kinase inhibitors that interrupt a critical step in thetumor's growth process. "These approaches are targeted therapies -- aimed in highlyselective ways at cancer cells, but sparing healthy cells," saidMaris. "But in order to bes...

Lipitor Reduced the Risk of Coronary Events by Half and Stroke by Nearly One-Third in High-Risk Patients with Type 2 Diabetes Who Experienced a Recent Stroke

...tors for heart disease such as familyhistory, high blood pressure, age, low HDL ("good" cholesterol) orsmok... avoid serious druginteractions. Doctors should do blood tests to check liver functionbefore and during treatment and may adjust the dose. The mostcommon sid...

New Poll Shows Men, Women Incorrectly Blame Symptoms of Low Testosterone on Normal Aging

...doctor determine if the patienthas hypogonadism. A blood test can confirm hypogonadism bymeasuring testosterone levels. The doctor will then determine ifthe patient is a candidate for testosterone replacement therapyand, if so, which treatment options are right for him. About the Survey Methodology This ...
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(Date:5/15/2008)... , May 15, 2008 (BRONX, NY) Contrary to long-he...he risk of death, according to investigators from ... University. They reached their conclusion after e...ntative sample of adults in the U.S. The Einstein ...eased risk of death from cardiovascular disease (C...
(Date:5/15/2008)... , CAMBRIDGE, Mass.--MIT engineers have improved ...than 50 percent through technology that could help...ices find a much broader market, particularly in p...he work is also considerably less expensive than i...r advantages. , Our goal is to replace tradition...
(Date:5/15/2008)... , Stowers Institute researchers Karen Staehling-...logy, and Olivier Pourqui, Ph.D., Investigator, co...o show that genes known to cause spinal mutations ...rtant role in human patients with congenital verte...ed today on the Web site of the American Journal o...
(Date:5/15/2008)... , An acclaimed Nottingham scientist and his cele...e degrees at the same graduation ceremony. Last y...and both received the CBE. , The University of N...Poliakoff CBE FRS, and his brother, the acclaimed ... now to be recognised together for their remarkabl...
Breaking Biology News(10 mins):New study casts further doubt on risk of death from higher salt intake 2MIT creates new material for fuel cells 2MIT creates new material for fuel cells 3Stowers Institute researchers identify gene linked to vertebral defects in patient populations 2Boffinry and Baftas: Brothers' double doctorates 2Daniel Magilavy M D Joins Rigel as Vice President of Clinical Research 12699 1Daniel Magilavy M D Joins Rigel as Vice President of Clinical Research 12699 2Daniel Magilavy M D Joins Rigel as Vice President of Clinical Research 12699 3Galichia Heart Hospital Lowers Cost of Bypass to 2410K 12697 1Three Expert Opinion Journals now Publishing Original Research 3508 1Three Expert Opinion Journals now Publishing Original Research 3508 2Lotus Pharmaceuticals Raises 245 Million in Private Placement 12696 1Lotus Pharmaceuticals Raises 245 Million in Private Placement 12696 2Lotus Pharmaceuticals Raises 245 Million in Private Placement 12696 3
(Date:5/16/2008)...ntry needs is more unemployed politicians - and ec...tCall/ -- Although nearly all,voters place health ...ist,a looming federal budgetary crunch means none...urrent presidential candidates is likely to become...y Leader Bill Frist., Jousting with Princeton Uni...
(Date:5/16/2008)...year-old Chinese students learn the lesson of help...uan earthquake, NANJING, China, May 16 /PRNewswir...earthquake, even the youngest members of China are...ef efforts. All around the,country, schools are ru...Led by the school,s principal, Ms. Zhang Lijun, th...
(Date:5/16/2008)...May 16 /PRNewswire-FirstCall/ -- CryoCor, Inc. (Na...he treatment of cardiac,arrhythmias, announced tod...oCor common stock filed a complaint in the Superio...Diego, naming as defendants each member of the,Boa...entific Corporation.,The complaint is styled Secon...
(Date:5/16/2008)...Y., May 16 /PRNewswire-USNewswire/ -- Karin Weisbu...he nonprofit publisher of,Consumer Reports magazin...of the Year at CU,s Yonkers headquarters today., ...d. She bundles up in,the winter and rides in shirt...akes her along Quaker Ridge in New Rochelle, down ...
Breaking Medicine News(10 mins):Health News:Former Senate Majority Leader, Princeton Economist Joust on Future of Health Care 2Health News:Former Senate Majority Leader, Princeton Economist Joust on Future of Health Care 3Health News:Chinese Preschoolers Participate in Fund Drive to Help the Victims of Sichuan Quake 2Health News:CryoCor, Inc. Subject of Lawsuit Relating to Tender Offer and Merger 2Health News:CryoCor, Inc. Subject of Lawsuit Relating to Tender Offer and Merger 3Health News:CryoCor, Inc. Subject of Lawsuit Relating to Tender Offer and Merger 4Health News:Westchester Cycle Club Awards Consumers Union Staffer Karin Weisburgh Commuter of the Year 2Health News:Westchester Cycle Club Awards Consumers Union Staffer Karin Weisburgh Commuter of the Year 3
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